LOCUS       NM_001108079            1989 bp    mRNA    linear   ROD 06-DEC-2024
DEFINITION  Rattus norvegicus carbohydrate sulfotransferase 11 (Chst11), mRNA.
ACCESSION   NM_001108079 XM_001079715 XM_235007
VERSION     NM_001108079.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1989)
  AUTHORS   Izumikawa,T., Okuura,Y., Koike,T., Sakoda,N. and Kitagawa,H.
  TITLE     Chondroitin 4-O-sulfotransferase-1 regulates the chain length of
            chondroitin sulfate in co-operation with chondroitin
            N-acetylgalactosaminyltransferase-2
  JOURNAL   Biochem J 434 (2), 321-331 (2011)
   PUBMED   21138417
REFERENCE   3  (bases 1 to 1989)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 1989)
  AUTHORS   Kluppel,M., Wight,T.N., Chan,C., Hinek,A. and Wrana,J.L.
  TITLE     Maintenance of chondroitin sulfation balance by
            chondroitin-4-sulfotransferase 1 is required for chondrocyte
            development and growth factor signaling during cartilage
            morphogenesis
  JOURNAL   Development 132 (17), 3989-4003 (2005)
   PUBMED   16079159
REFERENCE   5  (bases 1 to 1989)
  AUTHORS   Okuda,T., Mita,S., Yamauchi,S., Matsubara,T., Yagi,F., Yamamori,D.,
            Fukuta,M., Kuroiwa,A., Matsuda,Y. and Habuchi,O.
  TITLE     Molecular cloning, expression, and chromosomal mapping of human
            chondroitin 4-sulfotransferase, whose expression pattern in human
            tissues is different from that of chondroitin 6-sulfotransferase
  JOURNAL   J Biochem 128 (5), 763-770 (2000)
   PUBMED   11056388
REFERENCE   6  (bases 1 to 1989)
  AUTHORS   Yamauchi,S., Mita,S., Matsubara,T., Fukuta,M., Habuchi,H.,
            Kimata,K. and Habuchi,O.
  TITLE     Molecular cloning and expression of chondroitin 4-sulfotransferase
  JOURNAL   J Biol Chem 275 (12), 8975-8981 (2000)
   PUBMED   10722746
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079715.1, XM_235007.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN06680432, SAMN12840116
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..1989
                     /gene="Chst11"
                     /gene_synonym="C4ST1"
                     /note="carbohydrate sulfotransferase 11"
                     /db_xref="GeneID:314694"
                     /db_xref="RGD:1308400"
     exon            1..485
                     /gene="Chst11"
                     /gene_synonym="C4ST1"
                     /inference="alignment:Splign:2.1.0"
     CDS             368..1426
                     /gene="Chst11"
                     /gene_synonym="C4ST1"
                     /EC_number="2.8.2.5"
                     /note="C4ST; C4S-1; C4ST-1; chondroitin 4-sulfotransferase
                     1; chondroitin 4-O-sulfotransferase 1; carbohydrate
                     (chondroitin 4) sulfotransferase 11"
                     /codon_start=1
                     /product="carbohydrate sulfotransferase 11"
                     /protein_id="NP_001101549.1"
                     /db_xref="GeneID:314694"
                     /db_xref="RGD:1308400"
                     /translation="MKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSMLHPVMRRN
                     PFGVDICCRKGSRSPLQELYNPIQLELSNTAILHQMRRDQVTDTCRANSAMSRKRRVL
                     TPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLSGRGKYSDPMEIPANEAHVSAN
                     LKTLNQYSIPEINHRLKSYMKFLFVREPFERLVSAYRNKFTQKYNTSFHKRYGTKIIR
                     RQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEPFNEHWQTVYSLCHPCHIHYDLV
                     GKYETLEEDSNYVLRLAGVSGYLKFPTYAKSTRTTDEMTTEFFQNISAEHQTQLYEVY
                     KLDFLMFNYSVPNYLKLD"
     exon            486..571
                     /gene="Chst11"
                     /gene_synonym="C4ST1"
                     /inference="alignment:Splign:2.1.0"
     exon            572..1989
                     /gene="Chst11"
                     /gene_synonym="C4ST1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagggcaccg cggcggcggc accttccttc tcgcatcccg gtcgcccggc ccgcgaggag
       61 gcagcggcgg ccgcaggcgc cagcagagga ggcggcggag catcgagcag aggcgaggcg
      121 gaccggcagg agcgcgcggc cggggccacg catccccaca cttgcacacc aactcccgcg
      181 ccttgcaccc ccgagaccgg aatcgggggc tcggagagcc tcggtgaagc tagcgggagc
      241 cagctccgga gcccggccag ctccgttctg aacctcccgg gcgctggtcc ccccgcggcg
      301 gggtccccgc ttctgcgctc cggacgcgcc tcccggacag ccgggtcccc gcggccagga
      361 caaagccatg aagccggcgc tgctggaagt gatgaggatg aacagaattt gccggatggt
      421 gctggccact tgcttgggat cctttatctt ggtcatcttc tatttccaaa gtatgttgca
      481 cccagtcatg cggaggaatc cctttggcgt ggacatctgc tgccggaagg ggtctcggag
      541 tccactgcag gagctctaca atcccatcca gctggagctc tccaacactg ccatcctgca
      601 ccagatgaga cgggaccagg tgacagacac ctgccgggcc aacagcgcca tgagccgcaa
      661 gcgcagggtg ctgaccccca acgacctgaa gcacctggtg gtggatgagg accacgaact
      721 catctactgc tatgtaccca aggtggcgtg caccaactgg aagaggctca tgatggtcct
      781 gagcggccgg ggcaagtaca gcgaccccat ggagatccca gccaacgagg cccacgtgtc
      841 ggccaacctg aagaccctta accagtacag catcccagag atcaaccacc gcttgaaaag
      901 ctacatgaag ttcctgttcg tgcgggagcc cttcgagagg ctggtgtctg cctaccgcaa
      961 caagttcacg cagaagtaca acacctcctt ccacaagcgc tacggcacga agatcatccg
     1021 gcgccagcgg aagaacgcca cgcaggaggc cctgcgcaag ggggacgatg tcaagttcga
     1081 ggagttcgtg gcctacctca tcgaccccca cacccagcgc gaggagccct tcaacgagca
     1141 ctggcagacg gtctactccc tctgccaccc atgccacatc cactacgacc tcgtgggcaa
     1201 gtacgagacg ctggaggagg actccaatta cgtactgcgg ctggccgggg tgagcggcta
     1261 cctgaagttc cccacctatg caaagtccac ccgaactacc gacgagatga ccacggagtt
     1321 cttccagaac atcagcgccg agcaccagac acagctgtac gaagtctaca aactggactt
     1381 tttaatgttc aactactcag tgccaaacta cctgaagttg gattagaggg ctgcgggggg
     1441 cggggggggc ggttggggag agggagagaa tcctgctttt taatttaaga tttttatttg
     1501 tcaaaagaat tctatggata ccgggttatt ttgtaagtta atatgccttt cgggggagat
     1561 gctgcgagcg gcatggtaag aattatttaa aaaaaaaatc ctctgtgggg aaggacagct
     1621 gtctttgcag gggagcggcg tggattggcc ctgtttttag aagcggaccc ggcaacactg
     1681 tccgcagggt gtccttgtgt tctggtgaat cccacaaact gtgcgtccca taaagtctaa
     1741 tgagtcttat ttatggttat ttaaacgtgg tctctgtata ggcttctcac tgtgtcagca
     1801 gcctgctcct gtctttctgg aggaaaggac agtctgtgcc ttgctggcta tgtctggttt
     1861 ggggggcgtg gttacctccc cactgtcccg tgcggaatcc cacggtgaca gctgatggat
     1921 taccaccgtt caagaaacac tgctagaaat aagtacattg tccttgcggt aagaaacagg
     1981 gatgagact
//
