LOCUS       NM_080397               2631 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus carbohydrate sulfotransferase 10 (Chst10), mRNA.
ACCESSION   NM_080397
VERSION     NM_080397.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Nakagawa,N., Takematsu,H. and Oka,S.
  TITLE     HNK-1 sulfotransferase-dependent sulfation regulating
            laminin-binding glycans occurs in the post-phosphoryl moiety on
            alpha-dystroglycan
  JOURNAL   Glycobiology 23 (9), 1066-1074 (2013)
   PUBMED   23723439
REFERENCE   2  (bases 1 to 2631)
  AUTHORS   Kizuka,Y., Matsui,T., Takematsu,H., Kozutsumi,Y., Kawasaki,T. and
            Oka,S.
  TITLE     Physical and functional association of glucuronyltransferases and
            sulfotransferase involved in HNK-1 biosynthesis
  JOURNAL   J Biol Chem 281 (19), 13644-13651 (2006)
   PUBMED   16543228
  REMARK    GeneRIF: The function of glucuronyltransfease is relevant to the
            efficient sequential biosynthesis of the HNK-1 carbohydrate.
REFERENCE   3  (bases 1 to 2631)
  AUTHORS   Senn,C., Kutsche,M., Saghatelyan,A., Bosl,M.R., Lohler,J.,
            Bartsch,U., Morellini,F. and Schachner,M.
  TITLE     Mice deficient for the HNK-1 sulfotransferase show alterations in
            synaptic efficacy and spatial learning and memory
  JOURNAL   Mol Cell Neurosci 20 (4), 712-729 (2002)
   PUBMED   12213450
REFERENCE   4  (bases 1 to 2631)
  AUTHORS   Nagase,T., Shimoda,Y., Sanai,Y., Nakamura,S., Harii,K. and Osumi,N.
  TITLE     Differential expression of two glucuronyltransferases synthesizing
            HNK-1 carbohydrate epitope in the sublineages of the rat myogenic
            progenitors
  JOURNAL   Mech Dev 98 (1-2), 145-149 (2000)
   PUBMED   11044619
REFERENCE   5  (bases 1 to 2631)
  AUTHORS   Bakker,H., Friedmann,I., Oka,S., Kawasaki,T., Nifant'ev,N.,
            Schachner,M. and Mantei,N.
  TITLE     Expression cloning of a cDNA encoding a sulfotransferase involved
            in the biosynthesis of the HNK-1 carbohydrate epitope
  JOURNAL   J Biol Chem 272 (47), 29942-29946 (1997)
   PUBMED   9368071
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            [WARNING] On Jul 23, 2024 this sequence was replaced by
            NM_080397.3.
            
            On Nov 26, 2020 this sequence version replaced NM_080397.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF022729.1, SRR26360176.960783.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               JAXUCZ010000009.1  48618219-48618442   c
            225-356             JAXUCZ010000009.1  48606042-48606173   c
            357-448             JAXUCZ010000009.1  48597863-48597954   c
            449-683             JAXUCZ010000009.1  48595702-48595936   c
            684-789             JAXUCZ010000009.1  48591976-48592081   c
            790-2631            JAXUCZ010000009.1  48588575-48590416   c
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q22"
     gene            1..2631
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /note="carbohydrate sulfotransferase 10"
                     /db_xref="GeneID:140568"
                     /db_xref="RGD:621216"
     exon            1..224
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
     exon            225..356
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..1327
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /EC_number="2.8.2.-"
                     /note="sul-T; HNK1ST; raHNK-1ST; HNK-1 sulfotransferase"
                     /codon_start=1
                     /product="carbohydrate sulfotransferase 10"
                     /protein_id="NP_536322.1"
                     /db_xref="GeneID:140568"
                     /db_xref="RGD:621216"
                     /translation="MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFL
                     TAMPEAEKLRGEKHFSEVMKPTGKMLSESHPDQPPVYLERLELIRNACKEEALRNLSH
                     TEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHE
                     KNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIA
                     PGIIRKYRKNRTETRGIQFEDFVRYLGDPNRRWLDLQFGDHIIHWVTYVKLCAPCEIK
                     YSVIGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRR
                     LYARFEGDFKLFGYQKPDFLLN"
     exon            357..448
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
     exon            449..683
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
     exon            684..789
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
     exon            790..2631
                     /gene="Chst10"
                     /gene_synonym="Hnk-1st"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgggctgc ggtgggcggc ggtcttgcac cccggagctc gcacgtaccc agtttcctcc
       61 ttccggagtg gctgcactca ggcacccagc gggccggcgg gcgggtagcg gcgcggaggt
      121 ctgggcgggg cgggcctccc gggctccggg gacgcccaca ggccctgcga ggccagagca
      181 gagcgccggc ggcggggaag agcgcgagcg ccggggcacg gagggaagga tcatcggatg
      241 gaccctgttt gacaacatgc accaccagtg gctcctgctg gctgcatgct tttgggtgat
      301 tttcatgttc atggtggcca gcaagttcat cacgttgacc ttcaaagacc cggatgggta
      361 tagtgccaaa caggagtttg tgttcctgac ggccatgcca gaagcagaga agctaagagg
      421 agagaagcat ttttctgaag tcatgaagcc aactgggaag atgctttcgg agagccatcc
      481 tgatcagccc ccggtttatc tggagcggct ggagctcatc agaaacgctt gcaaggagga
      541 ggctctgcgg aacctctccc acaccgaggt ctctaagttt gtcctggatc gaatctttgt
      601 ctgtgacaag cacaagattc ttttctgtca gacccccaaa gtgggcaaca cccagtggaa
      661 gaaagtgctg atcgtcttaa atggagcatt ttcttctatt gaagagatcc cagaaaacgt
      721 ggttcatgac catgagaaaa atggccttcc acgtctctct tccttcagca aaataggaat
      781 tcagaagcga ttgaaaacat acttcaagtt ttttattgtg agggatccct ttgaaagact
      841 gatctctgcc tttaaggata agtttgttca caatcctcga tttgaacctt ggtacaggca
      901 cgagatagcc ccgggcatta ttaggaaata ccggaagaac cggacagaga cccggggtat
      961 ccagtttgaa gattttgtgc gctacctggg tgatccaaac cgcaggtggt tagaccttca
     1021 gtttggggac catatcatcc actgggtgac ctacgtaaaa ctctgtgcac cctgtgagat
     1081 aaagtacagt gtgattggac accacgagac cctggaggca gatgccccgt acatcctaaa
     1141 agaagctggc attgaccacc tggtgtcgta ccccactatc cctcccggca tcaccatgta
     1201 caacaggacc aaggtggagc agtacttcct gggcatcagc aaacgagaca tccggcgtct
     1261 ctatgcacgt tttgaagggg acttcaagct ctttgggtat cagaaaccag attttttgct
     1321 aaattaaggc atcagactcc tgaatattgc tagttccggg gatggctagg tggagatgtg
     1381 agaacatggg acctctaccc tgtcccatgg ttccgtgcat ggatgatgtt gggcgctgat
     1441 tacctgcttc actcgggtga caaatgctct gatgactccc ctccccagcc tgtgtcaccc
     1501 ccacgaaagg ttaggaaaga ctggacgtgt gcagacaggt agacagaccc agaggagcct
     1561 gcttccttca actgtcacat tgtccttggt gctgtgtcag cttgcctgta gtcgggtggt
     1621 gtcacccatg acctgtggac tgcacagacc cagcgctttc aagagagatg gggatactga
     1681 acggctgcaa aggttactgg ggcccatgca gagtcgaatc taagccagaa tgatacctct
     1741 tccttccatt ttgacactag ccacagatca gtcacttctt gagcttgagg ccctgtgaca
     1801 ctgggtggtg gtaatcacag aacaatctgg aagctctgat ctttcgggac ccaggctagc
     1861 tcttttttcc ggacctctga ccccacaagt acctgcttaa ttctgcagaa gagatccctt
     1921 ctggaaagtg agggcattat cagaacatct ctgacgacct agaacttggc atgggcaagg
     1981 aggaaccagc cggtcctggg aactctgggt gcaccgttgt ctctgacacc tgcttttgtc
     2041 ttcgacggcc ccaagggagc gagcagcagg ggcgtttcca cctctctcct gaacgcacct
     2101 ccctgtcctg agaggggaga gaagacaaag catttccggt ggacagagac gagcgcatgc
     2161 cgacgtgccg tgatgacgca caggcgtgca gtgcctgcat tgcggagtcc agtgctgtct
     2221 gcagactgtc aagtccgttc atgtcggcag acgggatcct acggtcctga atctaatagt
     2281 gccactgtcc tcgactgaaa gacccgcaag ttggataatc agattcgtca gcaataaaat
     2341 cctgggtgag gccgcctccg gtgatgtcgc cccaggtgac aagtcaccta acgtggcact
     2401 gaggccagcc ccagcaagaa agccacagca gctgtcacag ctgccaacca gcagcaaagg
     2461 gctattaaag atggagggac agtttctctg agtaagtccc tggcacatgc atctgcctgg
     2521 ggttgagagg aattgtgcca gtttttccta gaggtgacag ccctactctc aaaaagcctt
     2581 tcctgaactt gtaaatgtga aagtaaaata aaatttaaaa tgtgtgccaa a
//
