LOCUS       NM_001011955            2385 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus carbohydrate sulfotransferase 1 (Chst1), mRNA.
ACCESSION   NM_001011955 XM_230293
VERSION     NM_001011955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   2  (bases 1 to 2385)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   3  (bases 1 to 2385)
  AUTHORS   Bistrup,A., Bhakta,S., Lee,J.K., Belov,Y.Y., Gunn,M.D., Zuo,F.R.,
            Huang,C.C., Kannagi,R., Rosen,S.D. and Hemmerich,S.
  TITLE     Sulfotransferases of two specificities function in the
            reconstitution of high endothelial cell ligands for L-selectin
  JOURNAL   J Cell Biol 145 (4), 899-910 (1999)
   PUBMED   10330415
REFERENCE   4  (bases 1 to 2385)
  AUTHORS   Fukuta,M., Inazawa,J., Torii,T., Tsuzuki,K., Shimada,E. and
            Habuchi,O.
  TITLE     Molecular cloning and characterization of human keratan sulfate
            Gal-6-sulfotransferase
  JOURNAL   J Biol Chem 272 (51), 32321-32328 (1997)
   PUBMED   9405439
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Apr 22, 2021 this sequence version replaced NM_001011955.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086551.1, FQ211655.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000003.1  99015406-99015533
            129-258             JAXUCZ010000003.1  99026769-99026898
            259-2385            JAXUCZ010000003.1  99028088-99030214
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     gene            1..2385
                     /gene="Chst1"
                     /note="carbohydrate sulfotransferase 1"
                     /db_xref="GeneID:295934"
                     /db_xref="RGD:1308142"
     exon            1..128
                     /gene="Chst1"
                     /inference="alignment:Splign:2.1.0"
     exon            129..258
                     /gene="Chst1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..2385
                     /gene="Chst1"
                     /inference="alignment:Splign:2.1.0"
     CDS             301..1536
                     /gene="Chst1"
                     /EC_number="2.8.2.21"
                     /note="KSST; GST-1; KS6ST; KSGal6ST; keratan sulfate Gal-6
                     sulfotransferase;
                     galactose/N-acetylglucosamine/N-acetylglucosamine
                     6-O-sulfotransferase 1; carbohydrate (keratan sulfate
                     Gal-6) sulfotransferase 1"
                     /codon_start=1
                     /product="carbohydrate sulfotransferase 1"
                     /protein_id="NP_001011955.1"
                     /db_xref="GeneID:295934"
                     /db_xref="RGD:1308142"
                     /translation="MQCSWKAVLLLALASIAIQYTAIRTFTAKSFHTCPGLTETGLAE
                     RLCEEGPTFSYNLSRKTHVLILATTRSGSSFVGQLFNQHMDVFYLFEPLYHVQNTLIP
                     RFTQGKSPADRRVMLGASRDLLRSLYDCDLYFLENYIKPPPVNHTTDRVFRRGASRVL
                     CSRPVCDPPGASDLILEEGDCVRKCGLLNLTLAAEACRERSHVAIKTVRVPEVNDLRA
                     LVEDPRLNLKVIQLVRDPRGILASRSETFRDTYRLWRLWYGTGRKPYNLDVTQLTTVC
                     EDFSSSVSTGLMRPSWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIPLDSHVARWIQN
                     NTRGDPTLGKHKYGTVRNSAATAEKWRFRLSYDIVAFAQNACQHVLAQLGYKMATSEE
                     ELKNPAISLVEERDFRPFL"
ORIGIN      
        1 ggaggaggag gaggaggatg cctccgccac cgccaccacc acccgcgggc ccccggcgag
       61 cctgactcca gaccgaggat ggagccgacg ctgggcgctg cagcggctcc gggcgcgcag
      121 gccaccaggt aactgctgtg tgtgctgcat gtggttggaa gaagacccct gtccccagct
      181 gttcctttgg agcgaccttc tctacctgaa ggcctggggt gagccacctc catcccagga
      241 ccagctgagt tccagaagac cccgtgcctt ggagcagcag ccccatgacg gtgcccagcc
      301 atgcaatgtt cctggaaggc tgtcctcctc ctcgccctgg cctccattgc catccagtac
      361 acagccatcc gcacattcac tgccaagtct ttccacactt gccctgggct gacagaaact
      421 gggctggcag agcggctgtg tgaggagggc cccaccttct cctataacct ctccagaaag
      481 acccacgtcc tcatcttggc caccacacgc agtggttcat cctttgtggg ccagctcttc
      541 aaccagcaca tggatgtctt ctacctgttt gagcctctct accacgtcca gaacacgctc
      601 atcccccgct tcacccaggg caagagcccc gccgaccgca gggtcatgct aggtgccagc
      661 cgggacctgc tgaggagcct ttatgattgt gatctctact ttctggagaa ttacatcaag
      721 ccacctccgg tcaaccacac caccgaccgg gtcttccgcc gaggggccag cagggtcctc
      781 tgttcccgtc ctgtgtgtga ccctcctggg gcctctgacc tgatcctgga ggagggggac
      841 tgtgtgcgta agtgcggctt gctgaacctg accttggcag ctgaggcttg tcgtgagcgc
      901 agccatgtgg ccatcaagac tgtgcgggtg cctgaggtga atgacttgcg ggccctagtg
      961 gaagacccca ggttgaatct caaggtcatc cagctggtgc gagaccctcg tggtatctta
     1021 gcttctcgga gtgagacttt ccgggacaca taccgactct ggcggctttg gtacggcaca
     1081 gggaggaagc cctacaacct ggacgtgacc cagctgacca cagtgtgtga ggatttctct
     1141 agctctgtgt ctactggcct catgcggccc tcctggctca agggcaagta catgttggta
     1201 cgttatgagg acctggccag gaatccaatg aagaagacag aggagatcta cgaattcctg
     1261 ggtatccccc tggacagtca cgtggcacgc tggatccaga acaatacgag gggtgacccc
     1321 actttgggca agcacaaata cggcacagtg cgcaactctg cagccacagc tgagaagtgg
     1381 cgcttccgcc tctcctatga catcgtggcc tttgctcaga acgcctgcca gcatgtgctg
     1441 gcacagctgg gctacaagat ggccacctcg gaggaggagc tgaagaaccc agccatcagc
     1501 ctagtggagg agcgcgactt ccgccctttt ttgtgacctg ggtgtggtgg gggtgggagg
     1561 caggtggctc tggttttgct gatgtggacc tactacgggc cgttttttaa ctgttgcctt
     1621 atctctctcc tccctctccc accctgtttg tgtgtccttt ccacacaatc ccccaccccg
     1681 ggtctactcc tctcccacgc catctgcgca tccttcttgc ccttgtccac tccctttcct
     1741 cctgcctctt tctgcccctg aaatttgcac tatgtctctg gaggggaaca ctgggcagag
     1801 ggcgtgtgat gtggggttac agccccccac cccatttaga cacaaggctg ctgggtctct
     1861 atgcggatgg ggacaatgtt tacaggcacc cagtcacaca ttcacgtgtg cacacaggca
     1921 cacgacgaga ggcaccccag cacatagctt gtagtttttg caattgtctt ctccaggtaa
     1981 taggatggac acaaaggggc cacacccccc agtttaagaa aagagtccat cccaaccccc
     2041 tccctgctcc tcccctggag cagggcaccc atccctcctg cacacccttg cctggtggtg
     2101 agcagggttt tactgtgagg tgaattggga ttactttctt tctatttggt ttgtggtgag
     2161 cttgtctgtc tgagtcttgt gtctacccct agaccagtaa tggctaatga atcttagaaa
     2221 tttctgattg atcttggggt ccctctgtga tatttctttg tgccaaaaag atataaaaaa
     2281 agacaaaaat atgtgaatca gtttgctaaa tgaaaattga aatgctttat ttgtgttttc
     2341 tgtaaataaa aatgtgcagc actgcctgcg tgtgatttgg agaaa
//
