LOCUS       NP_001011955             411 aa            linear   ROD 31-MAR-2024
DEFINITION  carbohydrate sulfotransferase 1 [Rattus norvegicus].
ACCESSION   NP_001011955 XP_230293
VERSION     NP_001011955.1
DBSOURCE    REFSEQ: accession NM_001011955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 411)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   2  (residues 1 to 411)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   3  (residues 1 to 411)
  AUTHORS   Bistrup,A., Bhakta,S., Lee,J.K., Belov,Y.Y., Gunn,M.D., Zuo,F.R.,
            Huang,C.C., Kannagi,R., Rosen,S.D. and Hemmerich,S.
  TITLE     Sulfotransferases of two specificities function in the
            reconstitution of high endothelial cell ligands for L-selectin
  JOURNAL   J Cell Biol 145 (4), 899-910 (1999)
   PUBMED   10330415
REFERENCE   4  (residues 1 to 411)
  AUTHORS   Fukuta,M., Inazawa,J., Torii,T., Tsuzuki,K., Shimada,E. and
            Habuchi,O.
  TITLE     Molecular cloning and characterization of human keratan sulfate
            Gal-6-sulfotransferase
  JOURNAL   J Biol Chem 272 (51), 32321-32328 (1997)
   PUBMED   9405439
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 11, 2005 this sequence version replaced XP_230293.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086551.1, FQ211655.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     Protein         1..411
                     /product="carbohydrate sulfotransferase 1"
                     /EC_number="2.8.2.21"
                     /note="KSST; GST-1; KS6ST; KSGal6ST; keratan sulfate Gal-6
                     sulfotransferase;
                     galactose/N-acetylglucosamine/N-acetylglucosamine
                     6-O-sulfotransferase 1; carbohydrate (keratan sulfate
                     Gal-6) sulfotransferase 1"
                     /calculated_mol_wt=46754
     Site            2..23
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     Site            56
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     Site            145
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     Site            189
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     Region          <200..384
                     /region_name="Sulfotransfer_1"
                     /note="Sulfotransferase domain; cl21551"
                     /db_xref="CDD:473908"
     Site            334
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     Region          337..339
                     /region_name="Cell attachment site. /evidence=ECO:0000255"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RJQ0.1)"
     CDS             1..411
                     /gene="Chst1"
                     /coded_by="NM_001011955.2:301..1536"
                     /db_xref="GeneID:295934"
                     /db_xref="RGD:1308142"
ORIGIN      
        1 mqcswkavll lalasiaiqy tairtftaks fhtcpgltet glaerlceeg ptfsynlsrk
       61 thvlilattr sgssfvgqlf nqhmdvfylf eplyhvqntl iprftqgksp adrrvmlgas
      121 rdllrslydc dlyflenyik pppvnhttdr vfrrgasrvl csrpvcdppg asdlileegd
      181 cvrkcgllnl tlaaeacrer shvaiktvrv pevndlralv edprlnlkvi qlvrdprgil
      241 asrsetfrdt yrlwrlwygt grkpynldvt qlttvcedfs ssvstglmrp swlkgkymlv
      301 ryedlarnpm kkteeiyefl gipldshvar wiqnntrgdp tlgkhkygtv rnsaataekw
      361 rfrlsydiva faqnacqhvl aqlgykmats eeelknpais lveerdfrpf l
//
