LOCUS       NM_001005906            2946 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus chondroitin polymerizing factor (Chpf), mRNA.
ACCESSION   NM_001005906 XM_237306
VERSION     NM_001005906.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2946)
  AUTHORS   Dorval V, Smith PY, Delay C, Calvo E, Planel E, Zommer N, Buee L
            and Hebert SS.
  TITLE     Gene network and pathway analysis of mice with conditional ablation
            of Dicer in post-mitotic neurons
  JOURNAL   PLoS One 7 (8), e44060 (2012)
   PUBMED   22952873
REFERENCE   2  (bases 1 to 2946)
  AUTHORS   Ogawa H, Hatano S, Sugiura N, Nagai N, Sato T, Shimizu K, Kimata K,
            Narimatsu H and Watanabe H.
  TITLE     Chondroitin sulfate synthase-2 is necessary for chain extension of
            chondroitin sulfate but not critical for skeletal development
  JOURNAL   PLoS One 7 (8), e43806 (2012)
   PUBMED   22952769
REFERENCE   3  (bases 1 to 2946)
  AUTHORS   Yada T, Gotoh M, Sato T, Shionyu M, Go M, Kaseyama H, Iwasaki H,
            Kikuchi N, Kwon YD, Togayachi A, Kudo T, Watanabe H, Narimatsu H
            and Kimata K.
  TITLE     Chondroitin sulfate synthase-2. Molecular cloning and
            characterization of a novel human glycosyltransferase homologous to
            chondroitin sulfate glucuronyltransferase, which has dual enzymatic
            activities
  JOURNAL   J Biol Chem 278 (32), 30235-30247 (2003)
   PUBMED   12761225
REFERENCE   4  (bases 1 to 2946)
  AUTHORS   Kitagawa H, Izumikawa T, Uyama T and Sugahara K.
  TITLE     Molecular cloning of a chondroitin polymerizing factor that
            cooperates with chondroitin synthase for chondroitin polymerization
  JOURNAL   J Biol Chem 278 (26), 23666-23671 (2003)
   PUBMED   12716890
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083617.1.
            
            On Oct 23, 2004 this sequence version replaced XM_237306.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083617.1, SRR8487227.305526.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093045, SAMN16093049
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2946
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..2946
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /note="chondroitin polymerizing factor"
                     /db_xref="GeneID:316533"
                     /db_xref="RGD:1359458"
     exon            1..508
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..2519
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /EC_number="2.4.1.175"
                     /codon_start=1
                     /product="chondroitin sulfate synthase 2"
                     /protein_id="NP_001005906.1"
                     /db_xref="GeneID:316533"
                     /db_xref="RGD:1359458"
                     /translation="MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQ
                     PGDSELPPRGNTNAARRPNSVQPGAERERPGADESWEPRVLPYHPAQPGQATKKAVRT
                     RYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMA
                     VVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLTGHLSLASAT
                     HLYLGRPQDFIGGETTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLG
                     RCILDATGIGCTGHHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVHDPVHMYQLHK
                     AFARAELDRTYQEIQELQWEIQNTSRLAADGERASTWPVGIPAPSRPASRFEVLRWDY
                     FTEQHTFSCADGSPRCLLRGADQADVADVLGTALEELNRRYQPALRLQKQQLVNGYRR
                     FDPARGMEYTLDLQLEALTPQGGRWPLTHRVQLLRPLSRVEILPVPYVTEASRVTVLL
                     PLAAAECDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHADVFAPVKAHVA
                     ELERRFPGARVPWLSVQTSAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCR
                     MHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAA
                     RGRLVAVSEQEEELLESLDVYELFLRFSSLHVLRAVEPALLQRYRAQPCSARLSEDLY
                     HRCRQSVLEGLGSRTQLAMLLFEQEQGNST"
     exon            509..1082
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1262
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..2917
                     /gene="Chpf"
                     /gene_synonym="D1bwg1363e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgggagg ccccggcgcg cagtgctgct ctaagggcta cagacctacc cgggggttcc
       61 gggcttgagc tactatctct gctccgcggg gagggagcgg gcccgcctgc tgggctcggg
      121 ccctccggat ccgccccctc cccggtcccg ccccctcgga gccgcctggg gctgcgcggg
      181 ggcccgggac ccgctgtcgg gacgccatgc gggcgtcgct gctgctgtcc gtgctgcggc
      241 ctgcggggcc ggtggccgtg ggcatctctc tgggcttcac cctgagctta ctcagcgtca
      301 cctgggtgga ggagccttgc ggacccggac caccccaacc cggcgactct gaactaccgc
      361 cgcgcggcaa caccaacgcg gcgcgccggc ccaactcggt gcagcccgga gcggagcgcg
      421 agaggcccgg ggccgacgaa agctgggagc ctcgtgtctt gccctaccat cccgcccagc
      481 caggccaggc taccaagaag gccgtcagaa ctcggtatat cagcacggaa ctgggcatca
      541 ggcagaagct gctagtggca gtgctgacct cacaggccac gttgcctaca ctgggtgtgg
      601 ctgtaaaccg aactctggga caccgattgg agcatgtagt gttcctgacc ggtgcgaggg
      661 gccgccggac accatcaggc atggcggtgg tggcactggg cgaagagcgg cccatcggac
      721 acctgcacct ggcgctgcgc cacctgctgg agcaacacgg cgatgacttt gactggtttt
      781 tcctagtgcc tgatgccacc tacactgagg cgcatggact ggaccgccta actggccacc
      841 tcagccttgc ttcagcaacc cacctctatc ttggccgacc ccaggacttc atcggtggag
      901 agactacccc aggccgttac tgccacgggg gctttggagt gttgctgtct cgcacactac
      961 tacagcaact gcgcccccac ctggaaagct gccgtaatga catcgtcagt gctcgcccag
     1021 atgagtggtt gggccggtgc atccttgatg ccacaggcat tggctgtact ggtcaccatg
     1081 agggaatgca ctacaactat ctggaactga gccctgggga acctgtgcag gagggggacc
     1141 ctcgtttccg cagcgccttg acagcccacc ctgtgcatga ccctgtgcac atgtaccagc
     1201 tgcacaaagc ttttgcccgg gctgagctgg accgcacata ccaggagatt caagaactgc
     1261 agtgggagat ccagaatacc agcagactgg ctgctgatgg ggagagggct tctacctggc
     1321 cagtgggcat tccagcgccg tctcgccctg cctcgcgctt tgaggttctg cgctgggact
     1381 acttcacgga acagcacact ttctcctgtg ctgacggctc accccgctgc ctgctgcgtg
     1441 gggccgacca ggccgatgtg gctgatgtcc taggaacagc cttagaggag ctcaaccgcc
     1501 gttaccagcc agcactgcgg ctccagaagc aacagctggt gaatggctac cggcgttttg
     1561 atccagcccg aggtatggag tacacactag acttgcagct ggaagcgctg acgccccagg
     1621 gtggccgctg gcccctcacc cacagggtac agctccttcg gcccttgagc cgagtggaga
     1681 tcttgcctgt gccctatgtc accgaggctt ctcgggtcac tgtgctgctg cctctggctg
     1741 cagcagagtg tgacctggca tctggcttcc tagaagcctt tgccactgca gcactggaac
     1801 ctggcgatgc cgcagccttg accctgctgc tgctgtatga gccacgccag gcccagcggg
     1861 cagcccacgc agatgtcttc gcacccgtca aagcccacgt ggccgagcta gagcggcgtt
     1921 tccctggtgc ccgagtgccc tggctcagtg tacagacatc cgcgccctct ccgctgcgcc
     1981 tcatggatct actctccaag aagcacccgc tggacactct gttcctgctg gccgggccag
     2041 acacagtgct cacacccgac ttcctgaacc gctgccgcat gcacgccatc tcgggctggc
     2101 aagccttctt tcccatgcac ttccaggcct tccaccctgc tgtggctcca cctcagggcc
     2161 ctgggccacc agaactgggc cgtgacaccg gccactttga tcgtcaggct gccagcgagg
     2221 catgcttcta caactccgac tatgtggcgg cccgtggacg gctggtggca gtctccgagc
     2281 aggaggagga gctgctggag agcctggatg tgtatgagtt gtttctacgc ttctctagct
     2341 tgcatgtgct gagggcagtg gaaccagcct tgctgcagcg ctaccgggcc cagccatgca
     2401 gcgctcggct cagcgaggac ctttatcacc gctgtcgcca gagcgtgctt gagggccttg
     2461 gctcccgcac ccagcttgcc atgctgctct ttgaacagga acagggtaac agcacctaag
     2521 gcctgcacct gtccctgctc ttccgcagta acctggagct gcatgccagc ctcgctggac
     2581 agggccggct gtagcctcag accctagggc agcccactgg tcctttgtct cttgctttgt
     2641 tggacccatg ggctcaggac aagccctgag acaggtgccc tagagccatc ctttcttgtc
     2701 cagtgtccct gcccccttga cgctgctgat tcaggctgtg gcctcttgtg tttatgccta
     2761 acgccagcca tgcttccggg gctcttgtcc tgggggctgg gctgtagatg agttgttgga
     2821 gaaggtgaga gctgagaaag gagggttacg ggatctactg ccttctccct tctggatcca
     2881 cggtgaagcc ctggcttaat aaactggcta agagtgtaaa aaaaaaaaaa aaaaaaaaaa
     2941 aaaaaa
//
