LOCUS       NM_001108128            2564 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus cysteine and histidine rich domain containing 1
            (Chordc1), mRNA.
ACCESSION   NM_001108128 XM_001075005 XM_235878
VERSION     NM_001108128.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2564)
  AUTHORS   Hong,T.J., Kim,S., Wi,A.R., Lee,P., Kang,M., Jeong,J.H. and
            Hahn,J.S.
  TITLE     Dynamic nucleotide-dependent interactions of cysteine- and
            histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1
            and melusin with cochaperones PP5 and Sgt1
  JOURNAL   J Biol Chem 288 (1), 215-222 (2013)
   PUBMED   23184943
REFERENCE   2  (bases 1 to 2564)
  AUTHORS   Michowski,W., Ferretti,R., Wisniewska,M.B., Ambrozkiewicz,M.,
            Beresewicz,M., Fusella,F., Skibinska-Kijek,A., Zablocka,B.,
            Brancaccio,M., Tarone,G. and Kuznicki,J.
  TITLE     Morgana/CHP-1 is a novel chaperone able to protect cells from
            stress
  JOURNAL   Biochim Biophys Acta 1803 (9), 1043-1049 (2010)
   PUBMED   20493909
REFERENCE   3  (bases 1 to 2564)
  AUTHORS   Ferretti,R., Palumbo,V., Di Savino,A., Velasco,S., Sbroggio,M.,
            Sportoletti,P., Micale,L., Turco,E., Silengo,L., Palumbo,G.,
            Hirsch,E., Teruya-Feldstein,J., Bonaccorsi,S., Pandolfi,P.P.,
            Gatti,M., Tarone,G. and Brancaccio,M.
  TITLE     Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication
            and tumorigenesis
  JOURNAL   Dev Cell 18 (3), 486-495 (2010)
   PUBMED   20230755
REFERENCE   4  (bases 1 to 2564)
  AUTHORS   Gano,J.J. and Simon,J.A.
  TITLE     A proteomic investigation of ligand-dependent HSP90 complexes
            reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein
  JOURNAL   Mol Cell Proteomics 9 (2), 255-270 (2010)
   PUBMED   19875381
REFERENCE   5  (bases 1 to 2564)
  AUTHORS   Brancaccio,M., Menini,N., Bongioanni,D., Ferretti,R., De Acetis,M.,
            Silengo,L. and Tarone,G.
  TITLE     Chp-1 and melusin, two CHORD containing proteins in vertebrates
  JOURNAL   FEBS Lett 551 (1-3), 47-52 (2003)
   PUBMED   12965203
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473993.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_235878.4, XM_001075005.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2564
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..2564
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /note="cysteine and histidine rich domain containing 1"
                     /db_xref="GeneID:315447"
                     /db_xref="RGD:1304679"
     exon            1..213
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1145
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /note="morgana; CHORD domain-containing protein 1;
                     cysteine and histidine-rich domain (CHORD)-containing,
                     zinc-binding protein 1; cysteine and histidine-rich domain
                     (CHORD)-containing 1"
                     /codon_start=1
                     /product="cysteine and histidine-rich domain-containing
                     protein 1"
                     /protein_id="NP_001101598.1"
                     /db_xref="GeneID:315447"
                     /db_xref="RGD:1304679"
                     /translation="MALLCYNRGCGQRFDPEANADDACTYHPGVPVFHDALKGWSCCK
                     RRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKP
                     VEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEEDKKEEDSDEIKIGTSCKNG
                     GCSKTYQGLQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTRGKHVW
                     TKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVEANSTLLNVHIVFEGEKEF
                     HQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPTTKKQEKQKDIAD"
     exon            214..263
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            264..320
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            321..478
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            479..582
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            583..641
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            642..712
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..818
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            819..938
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1001
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..2564
                     /gene="Chordc1"
                     /gene_synonym="CHP-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgcaaccg gaacgttcgg gaagattcct gaagcagtac cggcggcttc cggaagctag
       61 ctgcggcctg aacagtagtg ccggtgaggt gattgccgtg gtgattcact tctactcctg
      121 ggtggtgtgt gtttcgccgg gaaaacggaa tggcgctcct gtgctacaac cgcggctgtg
      181 gccagcgttt cgaccccgag gccaatgcgg atgatgcttg cacataccac ccaggcgttc
      241 ctgtctttca tgatgcccta aagggttggt cttgctgtaa gagaagaaca acggattttt
      301 ctgacttctt aagtattgta ggatgtacaa aaggtaggca taatagtgag aagccaccgg
      361 aaccagtcaa gcccgaagtc aagactactg agaagaagga actatctgaa ttaaaaccca
      421 aatttcagga gcacatcatt caagccccta aaccagtaga agcaataaaa aggccaagcc
      481 cagatgagcc aatgacaaac ttggaattaa aaatatctgc ttccctaaaa caagcacttg
      541 ataaacttaa actgtcatct gggaatgaag aagataaaaa agaagaagac agtgatgaaa
      601 ttaagattgg gacttcttgt aaaaatggag ggtgttcaaa gacataccaa ggtctacaga
      661 gtctagaaga agtttgtgta tatcattctg gagtacccat tttccacgag gggatgaaat
      721 attggagctg ctgtagaaga aaaacttcag attttaatac attcttagcc caagagggat
      781 gtacaagagg gaaacatgta tggactaaaa aagatgctgg gaaaaaagtt gttccatgta
      841 gacacgactg gcatcagact gggggtgaag ttaccatctc agtgtatgct aaaaattctc
      901 tgccagaact cagtcaagta gaagcaaata gtacattgtt aaatgtacac attgtatttg
      961 aaggagagaa agaatttcat caaaatgtga aactatgggg tgtgattgat gttaaacgaa
     1021 gttacgtaac tatgactgca acgaagattg agatcactat gagaaaggca gagcccatgc
     1081 agtgggcaag tcttgaacta cctacaacca aaaagcagga gaaacaaaaa gatatagctg
     1141 attgattaga agagaaatag aaaccttgtc taacttagag ttcttaatgt gtgtggtgat
     1201 gtagttgctt gctgctgcaa tcgttttgtt gtttttaatc tgccatttta gggttatcat
     1261 gaggttcttc aaagccaaag tctgttaaat ttttgtgcct ctatcttctt ttgagttgca
     1321 taatatgatt attcaagtct cttcactaga actatagttg ttgcccttac acttgaaggg
     1381 agggaaagga cccataagta taactgcagt acagtatatt ttggtataaa ttattatgaa
     1441 caggaaatga cagaggattt ttttttttaa attctgataa ctcctttttc ccttaaatgg
     1501 gaaagcaaag tggtatatag aaaaaattgg attggccttt ccatgaacat ttgttactat
     1561 aattcttgaa aatttttaag gaaagacttt tctttgtttt tccctataca gtggttactt
     1621 tttatagtac tacttctgaa gcagtggagt caaaatgtgt gtgctggcta agtttataat
     1681 ttgtttgcag ttcaattaat ttcagaaagt tgcatcaata cttgcattac ctggcaagca
     1741 gtataattta agtctataga aaataaacta agattataga attatcaatt tggttaaaat
     1801 tcataagagt aagcaataat gttaaaatct ctttcctgat tacttaaagt actctttatg
     1861 gtattttgac taaattgtat ctgatttgta gtctaaacac tcttatgaat tatatctgtc
     1921 tccctgatga aaaactgtat ttaaattgtg aatgtgtagc ttcgttgaaa tatattaagg
     1981 tgtgtgttga ggcttgaatc tgaaatgtac ctggaggctt gttttgagct gttggtcttt
     2041 caacttaagg ctctattttg aaggctgtga aaccttaagg atatcgatgg gtgaggatta
     2101 tatactcctg ctggtcttat ccagtcagga tgtatgaatt acctctgtcc catacttcca
     2161 ctgctgcctc ctcagccatt atagattgta tcctctggaa ccgtgagcca aaataataaa
     2221 ccttaccttc cttgagttgt ttctgtcatg tgctttggtc aagacaagaa aagttatata
     2281 ctacataaaa attatagact gtattttaga tcagctgaat attatgttaa gttactatag
     2341 tataattctt tggagttatt ttaagggttt catgaagagt tttacacata taatggttat
     2401 atgttctact ttattttcat taattgtaga tgacacagat aaacttagat cgaaataaaa
     2461 cttgaaggtc tttatttgcc acactctttg gtgttaatgg aatcctcaca aagtttcatt
     2521 atagtcaaaa tactgtttta gttaatagag aatctgtatg gggg
//
