LOCUS       NM_032084               3111 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus chimerin 2 (Chn2), mRNA.
ACCESSION   NM_032084 XM_346700
VERSION     NM_032084.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3111)
  AUTHORS   Leung,T., How,B.E., Manser,E. and Lim,L.
  TITLE     Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21
            ras-related rac is specifically expressed in granule cells and has
            a unique N-terminal SH2 domain
  JOURNAL   J Biol Chem 269 (17), 12888-12892 (1994)
   PUBMED   8175705
REFERENCE   2  (bases 1 to 3111)
  AUTHORS   Leung,T., How,B.E., Manser,E. and Lim,L.
  TITLE     Germ cell beta-chimaerin, a new GTPase-activating protein for
            p21rac, is specifically expressed during the acrosomal assembly
            stage in rat testis
  JOURNAL   J Biol Chem 268 (6), 3813-3816 (1993)
   PUBMED   8440677
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 1, 2020 this sequence version replaced NM_032084.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.16482.1,
                                           SRR26643297.16122.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-184               JAXUCZ010000004.1  84478989-84479172
            185-223             JAXUCZ010000004.1  84616794-84616832
            224-279             JAXUCZ010000004.1  84633698-84633753
            280-311             JAXUCZ010000004.1  84654905-84654936
            312-425             JAXUCZ010000004.1  84657956-84658069
            426-711             JAXUCZ010000004.1  84659806-84660091
            712-789             JAXUCZ010000004.1  84708364-84708441
            790-874             JAXUCZ010000004.1  84723297-84723381
            875-1048            JAXUCZ010000004.1  84727123-84727296
            1049-1126           JAXUCZ010000004.1  84729906-84729983
            1127-1264           JAXUCZ010000004.1  84732632-84732769
            1265-1370           JAXUCZ010000004.1  84734481-84734586
            1371-3111           JAXUCZ010000004.1  84736328-84738068
FEATURES             Location/Qualifiers
     source          1..3111
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..3111
                     /gene="Chn2"
                     /note="chimerin 2"
                     /db_xref="GeneID:84031"
                     /db_xref="RGD:620140"
     exon            1..184
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..1542
                     /gene="Chn2"
                     /note="beta-chimerin; chimerin (chimaerin) 2; rho
                     GTPase-activating protein 3"
                     /codon_start=1
                     /product="beta-chimaerin"
                     /protein_id="NP_114473.2"
                     /db_xref="GeneID:84031"
                     /db_xref="RGD:620140"
                     /translation="MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRII
                     CPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQT
                     LNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTTNPIYEHIGYAT
                     LLREKVSRRLSRSKNESRKAGVTHEEHTPVEKISSLVRRAALTHNDNHFNYEKTHNFK
                     VHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYC
                     CDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEK
                     ADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADERLEAVHEVL
                     MLLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTLHDM
                     RYQKLIVQILIENEDVLF"
     exon            185..223
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            224..279
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            280..311
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            312..425
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            426..711
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            712..789
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            790..874
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1048
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1126
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1264
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1370
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..3111
                     /gene="Chn2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggccggt gcttcccgcg cgtccccagg actttgccat gggctggggg ccgcgcgggc
       61 tgcgagcggc cggccgaggg cagcggcgac gccgcccgca ccgggactga gcaagcagcg
      121 acgcgcggcg ccgagatggc agcgtccagc aactctagtc tgtccggctc ctccgtgtcc
      181 tctgatgctg aggaatacca gcctccaata tggaaatcat acttgtatca gctccagcaa
      241 gaggcacctc gtcccaagag gatcatttgt ccccgggagg tggaaaacag accaaaatat
      301 tatggaagag agtttcatgg gatcatctcc cgggagcagg ctgatgagct tctaggcgga
      361 gtagagggtg cctacatcct tcgagagagc caacggcagc cgggatgcta cacgctggca
      421 ctgaggtttg gaaaccagac cttaaactac cggctcttcc atgatgggaa gcattttgtg
      481 ggtgagaaga ggttcgaatc cattcacgac ctggtgacag atggcttgat cacgctctac
      541 atagagacca aggctgctga gtacattgca aaaatgacca caaatcccat ctacgagcac
      601 atcggatacg ccactctcct cagagaaaaa gtgtccagaa ggctgagcag gtctaaaaat
      661 gagtcaagaa aggctggtgt cacccacgag gaacacacac cagtggagaa gatctcttca
      721 ctggtccgaa gagctgccct cacacacaat gacaaccact tcaactatga gaagacacac
      781 aacttcaagg tgcacacatt tcggggccca cactggtgtg aatactgtgc caattttatg
      841 tgggggctca tcgcccaggg agtccggtgt tcagattgtg ggttaaacgt acacaaacaa
      901 tgttccaagc acgtccccaa cgactgccag cccgatctca agaggatcaa gaaagtatac
      961 tgttgtgatc tcaccacact tgtaaaagct cacaacactc agagacccat ggtggtggac
     1021 atatgtattc gggaaattga agcaagagga ttaaaatcag aagggcttta cagagtctct
     1081 gggttcacag aacacattga agatgtcaag atggcgttcg acagagatgg tgaaaaggcg
     1141 gatatctctg ctaacatcta cccagacata aacatcatca ccggagccct gaaactgtac
     1201 ttcagagact tacccatccc catcatcaca tatgacacct attccaagtt tatagaggca
     1261 gcaaaaatct ccaatgcaga tgagaggctt gaagctgtcc atgaggtcct gatgctgctg
     1321 cctcctgccc actatgagac cctgcgctac ctgatgatcc atctcaaaaa ggttaccatg
     1381 aatgaaaagg acaatttaat gaacgcagaa aatctgggga tcgtgtttgg gcccaccctg
     1441 atgagacccc ctgaagacag caccctcacc accctccatg acatgcggta ccaaaagctg
     1501 atcgtgcaga ttttaataga aaacgaagat gttctgtttt agtccatcag ggaagtgagc
     1561 tgatagagct agtggaataa aaacgtttct cacacttggt ttgtcttttc aaacaagtgg
     1621 cagaatttcc tggaccacag tggattgcag agttggggac tgtgtctccc gcctccacat
     1681 gagagcaagg gtgaggggag gaaacccctt accttgggtc ttttgccgtg cctcgtatgt
     1741 atgtctgttt cgctggaaga gtgattaata aatctttctt taacttatta aaaaaatgta
     1801 gacttttaag cttcagtctt aacagtaata aaagggaact taattgataa aggtacttgg
     1861 taaagtatgc attttccacc ttcaacaaaa cataaaaaga agacaattct atatgttaaa
     1921 tgttaaatga aacctatatt gtaagatgta ttttatttta gctgcaagaa tgttatttta
     1981 ttttagcaaa tagaatccaa tgcagtgcat tggttattgc cctgtacctt gtccctcttc
     2041 ctgctgtgat gcctggtaaa cgttgaccgt gaatgcagta tcaccttgac atacctctgt
     2101 cctgatgagt tcttccatga aagttcaccc ctccccctat ccctgcttct cagtttccgc
     2161 tcctcagcac tggctttctg ccgtgagaca gtgtatgtgc atagcgtctc ttggatggtc
     2221 tgaagcattt accagtctcc tttctgtaag catttggtga cttcccaagg gatgttatag
     2281 aattagtcat ggcctctcca tatctcccgt gcacatccta gaacatgccg agtatgctct
     2341 gctacaaaat gacttgagga cactggatgc cgctggaccg tgtcacagaa ttagcacttt
     2401 tcctcttctc agccaggacc tgcagatgga tgtcaatggc aagttgaaac tctttgccac
     2461 atttccatat ggacgaatca tgaaccttta ggatcattgt tgaatcttgt tccttacttt
     2521 cattttataa acctattatt aagttatgaa taaataaggt tgtttttaat caaatgtttt
     2581 cccttcataa aggttgctct gaagataatt taacatgatt ttattactag agacacacct
     2641 gttggttata tttatcttag catgagattt ccacaccaag atctctatat tttgtaacat
     2701 aggtgaaata tttaaaacag caaaaactgt acatttagat ttttaaagcc agtcacagtg
     2761 tctttccttt gattgtctaa gacaacctac gcactgacaa gacttgctta gagtgcccag
     2821 aagagaactg ccctgctaag gtgggagaga ctgcagagat gattgattgt cagccccccc
     2881 aggccctgca ggaagaatcg tggcatccgg gactcagttc ggcttactct ctgctgtcac
     2941 cgtccctccc gactgtacag atgtgtttgt tgtggcttct gtacttcttg atactgtcag
     3001 taataatctg gaaatggttt tattttgtga agtgagcaat actttgtaat ttatgacagt
     3061 gtaatggaag gaaaaccatt ctgtgtatta aatactctgt ctatcatttt g
//
