LOCUS       NM_001108872            2774 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus charged multivesicular body protein 7 (Chmp7),
            mRNA.
ACCESSION   NM_001108872 XM_001069293 XM_344430
VERSION     NM_001108872.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2774)
  AUTHORS   Gu,M., LaJoie,D., Chen,O.S., von Appen,A., Ladinsky,M.S.,
            Redd,M.J., Nikolova,L., Bjorkman,P.J., Sundquist,W.I., Ullman,K.S.
            and Frost,A.
  TITLE     LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in
            fission yeast and human cells
  JOURNAL   Proc Natl Acad Sci U S A 114 (11), E2166-E2175 (2017)
   PUBMED   28242692
REFERENCE   2  (bases 1 to 2774)
  AUTHORS   Vietri,M., Schink,K.O., Campsteijn,C., Wegner,C.S., Schultz,S.W.,
            Christ,L., Thoresen,S.B., Brech,A., Raiborg,C. and Stenmark,H.
  TITLE     Spastin and ESCRT-III coordinate mitotic spindle disassembly and
            nuclear envelope sealing
  JOURNAL   Nature 522 (7555), 231-235 (2015)
   PUBMED   26040712
REFERENCE   3  (bases 1 to 2774)
  AUTHORS   Morita,E., Colf,L.A., Karren,M.A., Sandrin,V., Rodesch,C.K. and
            Sundquist,W.I.
  TITLE     Human ESCRT-III and VPS4 proteins are required for centrosome and
            spindle maintenance
  JOURNAL   Proc Natl Acad Sci U S A 107 (29), 12889-12894 (2010)
   PUBMED   20616062
REFERENCE   4  (bases 1 to 2774)
  AUTHORS   Horii,M., Shibata,H., Kobayashi,R., Katoh,K., Yorikawa,C.,
            Yasuda,J. and Maki,M.
  TITLE     CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b
            and functions in the endosomal sorting pathway
  JOURNAL   Biochem J 400 (1), 23-32 (2006)
   PUBMED   16856878
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473951.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_344430.3, XM_001069293.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2774
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p11"
     gene            1..2774
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /note="charged multivesicular body protein 7"
                     /db_xref="GeneID:364419"
                     /db_xref="RGD:1308779"
     exon            1..394
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1448
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /note="CHMP family, member 7"
                     /codon_start=1
                     /product="charged multivesicular body protein 7"
                     /protein_id="NP_001102342.1"
                     /db_xref="GeneID:364419"
                     /db_xref="RGD:1308779"
                     /translation="MWSPEREAQAPTGGDPAGLLPPEWEEDEERMSFLFSAFKRSREV
                     NSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRG
                     ELQRESDFMASVDSSWISWGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKA
                     EEVYRLYQNSPLSSHPVVALSELSALCANSCPDERTFYLVLLQLQKEKRVTVLEQNGE
                     KIVKFARGPHAKVSPVNDVDVGVYQLMQSEQLLSQKVESLSQESERCKEEARRACRAG
                     KKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKL
                     SMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTT
                     KEPLDLLENPHETLYTNSVPKPRILDAELEAELEKLSLSEGGLVPSSKSPKRQLEPTL
                     "
     exon            395..566
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            567..752
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            753..886
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            887..935
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1055
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1154
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1215
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1395
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..2774
                     /gene="Chmp7"
                     /gene_synonym="RGD1308779"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcgtgaag gaaggacgga agccgagagg gacctggggc ggaaggggac ccgggccagg
       61 cttgtgttcg gttccttggc ggggctgggg ttccgatgtg gtccccggag cgggaggccc
      121 aggccccgac cgggggagac ccggcgggcc tcctgccgcc cgagtgggag gaggatgagg
      181 agcgcatgtc ttttctgttc tccgctttta agaggagtcg cgaggtgaac agcaccgact
      241 gggacagcaa gatgggcttc tgggctccgt tggtgctgag ccacagccgc cgccaagggg
      301 ttgtgcgctt gcgactgcgg gacttgcagg aggccttcca gcgcaaaggc agtgttccgt
      361 tggggctggc taccgtgctg caggacctgc tgcgtcgagg tgagctgcag cgagaatcag
      421 acttcatggc cagtgtggac agcagctgga tttcctgggg ggttggagtc tttctgctga
      481 agcccctcaa gtggactctt tctaacatgc tgggggataa caaagttcca gcggaggagg
      541 tgctggtggc tgtggagctg cttaaggaaa aggctgagga ggtgtatcgc ctgtaccaga
      601 actcacccct ctcctcccac cctgtggtgg ctctgtcaga actgagtgct ctgtgcgcca
      661 actcctgccc agatgagaga accttctacc tcgtgctgct gcagctacag aaggagaaga
      721 gagtcactgt cttagagcag aatggagaga agattgtgaa gtttgccagg ggaccacatg
      781 ccaaggtgtc tcctgtcaac gacgtggatg ttggggtcta ccagctgatg cagagtgaac
      841 agctcctctc tcaaaaggtt gagtcgttat cccaagagtc tgagaggtgc aaagaggaag
      901 cccgccgggc atgccgagca gggaagaagc agctggcact gaggtctctc aaggccaagc
      961 agaggacaga gaaacgcatt gaggcgctgc acgccaagct ggacactgtt caaggcatcc
     1021 tggatcgcat ctatgcctcg cagacagacc agatggtttt taatgcctac caagctggtg
     1081 tgggagcctt gaaactctcc atgaaggatg tcacagtgga gaaggcagag agccttgtgg
     1141 atcagatcca ggagctgtgt gacacgcagg atgaagtttc tcagactcta gctggtgggg
     1201 taaccaatgg tttagatttt gacagtgagg aactggagaa ggagttggac atcctccttc
     1261 aggacaccac caaagaacct ttggacctgc tcgaaaaccc ccatgagacg ctttatacca
     1321 acagtgtgcc taagcctagg atcttggatg ctgaacttga agctgaactt gagaaactat
     1381 ccttatcaga aggaggtttg gtcccaagca gtaaatctcc aaaaaggcaa ttggagccaa
     1441 ctctctaaag ccattgcagg aattcaagca aaggaccctc atgtattaga gatgcagctt
     1501 tgtgcgtgta catagttatt taatgaaaaa cactgagaag ttgtcagaag aggaggaaag
     1561 aaccacctgg atatatctgg atgctgccgc tcataccagg acagatccaa cttctggaag
     1621 ccatgctatg gaggcgtgct ctggtgatgt catggaccta ccttctcgtc tttatagtgc
     1681 cacaatttat acagttctgt gtttgaccca tcgtcttcat agcctgcagt tcttgccatt
     1741 ggctctgtta ggtttgtctt cacccaccaa cttcattcca gccagtgaag gtgaaaggtt
     1801 tgcagcttgg cccatcaaag ccagccctcc cttccactcc caaggttttt aaaccactca
     1861 ctcccctagc ctgtgcttta ttggaatggg agtcaaacga gttttattca gagagaccaa
     1921 cagccgggtg tctggagaaa cgctgtccac aagacgtttc tctacatgct tcctcagtct
     1981 ctgggcattc gtggctctga atgttggggt catggcggtt tccggggggc ttatgtgatt
     2041 gggggccacg gccacttcca tcttaggcag aagcaggtct gttgatgagg ttggggaagg
     2101 atcaatctgt cttttgaact tgagcaggag aaacacaaat aaactccagg ccccagggtg
     2161 tgaaagaagc tgggttctca atttggcccc attataaatg atgtgttttc tggagcaagc
     2221 cacacagcga gcaccacatt tacctgtttc ttgagcctga cactcaactg gcaggctccc
     2281 tgttaggatc tggaagcgtc ttaccatgta tccaccactc agggcagggg gcctgagcca
     2341 ggatgtgcaa taggaggagg tggcactcgc ctgctgcatc tgctgcatct gctgcatctg
     2401 ctgcatctgc tgtgtgctgc cttgggcctg ccctgccctg ccctgcccct gcctcctgca
     2461 ggcagctctg tgcttcggtg gactgcagaa caggcaggag atgtagatct gaatgctatg
     2521 ttggcagcgt ggagaagaaa catgacagcc acactgccag tctgctgccc agggacggtg
     2581 actgcctgga cctctttgca ctgcccctcc tgcttgtggt aacatggagc agaagggaga
     2641 actttgcctc gggccaggag cacgaatcac tgtctcccac ttggctttgg caaatggaat
     2701 actgggggtg aagaaaaaca atcactattt tttctttttt aatctggtaa ataattaaaa
     2761 gagaaaaaca ccag
//
