LOCUS       NM_001025410            1355 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus charged multivesicular body protein 5 (Chmp5),
            mRNA.
ACCESSION   NM_001025410 XM_216371
VERSION     NM_001025410.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Thiebaut,R., Esmiol,S., Lecine,P., Mahfouz,B., Hermant,A.,
            Nicoletti,C., Parnis,S., Perroy,J., Borg,J.P., Pascoe,L.,
            Hugot,J.P. and Ollendorff,V.
  TITLE     Characterization and Genetic Analyses of New Genes Coding for NOD2
            Interacting Proteins
  JOURNAL   PLoS One 11 (11), e0165420 (2016)
   PUBMED   27812135
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1355)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1355)
  AUTHORS   Morita,E., Colf,L.A., Karren,M.A., Sandrin,V., Rodesch,C.K. and
            Sundquist,W.I.
  TITLE     Human ESCRT-III and VPS4 proteins are required for centrosome and
            spindle maintenance
  JOURNAL   Proc Natl Acad Sci U S A 107 (29), 12889-12894 (2010)
   PUBMED   20616062
REFERENCE   5  (bases 1 to 1355)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 1355)
  AUTHORS   Shim,J.H., Xiao,C., Hayden,M.S., Lee,K.Y., Trombetta,E.S.,
            Pypaert,M., Nara,A., Yoshimori,T., Wilm,B., Erdjument-Bromage,H.,
            Tempst,P., Hogan,B.L., Mellman,I. and Ghosh,S.
  TITLE     CHMP5 is essential for late endosome function and down-regulation
            of receptor signaling during mouse embryogenesis
  JOURNAL   J Cell Biol 172 (7), 1045-1056 (2006)
   PUBMED   16567502
REFERENCE   7  (bases 1 to 1355)
  AUTHORS   Ward,D.M., Vaughn,M.B., Shiflett,S.L., White,P.L., Pollock,A.L.,
            Hill,J., Schnegelberger,R., Sundquist,W.I. and Kaplan,J.
  TITLE     The role of LIP5 and CHMP5 in multivesicular body formation and
            HIV-1 budding in mammalian cells
  JOURNAL   J Biol Chem 280 (11), 10548-10555 (2005)
   PUBMED   15644320
REFERENCE   8  (bases 1 to 1355)
  AUTHORS   Sutherland,H.G., Mumford,G.K., Newton,K., Ford,L.V., Farrall,R.,
            Dellaire,G., Caceres,J.F. and Bickmore,W.A.
  TITLE     Large-scale identification of mammalian proteins localized to
            nuclear sub-compartments
  JOURNAL   Hum Mol Genet 10 (18), 1995-2011 (2001)
   PUBMED   11555636
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097963.1.
            
            On Jul 18, 2005 this sequence version replaced XM_216371.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097963.1, EV770753.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..1355
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /note="charged multivesicular body protein 5"
                     /db_xref="GeneID:297995"
                     /db_xref="RGD:1305968"
     exon            1..110
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..701
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /note="chromatin-modifying protein 5"
                     /codon_start=1
                     /product="charged multivesicular body protein 5"
                     /protein_id="NP_001020581.1"
                     /db_xref="GeneID:297995"
                     /db_xref="RGD:1305968"
                     /translation="MNRFFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVK
                     YKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDT
                     KTTVDAMKLGVKEMKKAYKEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGTPELDE
                     DDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPA
                     S"
     exon            111..215
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            216..262
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            263..356
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            357..428
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            429..537
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            538..650
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
     exon            651..1327
                     /gene="Chmp5"
                     /gene_synonym="RGD1305968"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtatttctc cagtgtttgg gtttcctcgc cgccggccga gatgaaccga ttcttcggaa
       61 aagcgaaacc caaggctccg ccacctagcc tgactgactg cattgggacg gtggatagca
      121 gggcagaatc cattgacaaa aagatttccc ggttggatgc tgaactggtg aaatataagg
      181 accaaatcaa gaagatgaga gagggtcctg ctaagaacat ggtcaaacag aaagccctga
      241 gggttttaaa gcaaaaacgg atgtatgagc agcagcgaga caaccttgcc caacagtcct
      301 ttaacatgga gcaagctaat tacaccatcc agtcactgaa ggataccaaa accacggttg
      361 atgcaatgaa attgggagta aaggaaatga agaaggctta caaggaagta aaaattgacc
      421 agattgagga tttacaagac cagttggaag acatgatgga agatgcaaat gagatccagg
      481 aggccctggg ccgcagctac ggcaccccag aactggatga ggacgacctg gaagcagagt
      541 tggatgcgct gggcgatgag cttctggctg atgaggacag ctcttacttg gacgaagcag
      601 cttctgcacc ggcaattcca gagggcgttc ccactgacac aaaaaacaag gatggagtgc
      661 tggtggatga atttggactg ccacagattc cagcttcgta gacttggaac attccagtgt
      721 gtgatgtaaa aaaaaaaaaa aagtattctg ggactaggaa gtatctccca atttgccaaa
      781 cagatttacg tttctttcct ttctttggag gaaaagctaa ttacactgct cctgtatttt
      841 tatttttttc cattaaggaa ttcattgctt gggggaagct gtctttacta aaatttgatt
      901 cttttttttc cttaggaaag actaactgaa aagtaccttt gactttgtat gacttgtttt
      961 cattcattaa caataatctg aaattaaacc aaggagatga gactctaaat tctatatggt
     1021 agtatgatga tgtattaata agataaagat tattgatggg gttgatagta ttttcagaac
     1081 cattgtctat tgtggtactg tagatggctt taagtgatgg cctcctttga taggtttcgt
     1141 tgtgtcatgt gagcaagtca ttactctgtc tactgttgga atgaactgtc actactgcat
     1201 catgagttac tactttgatc ccatggttcc ctcggtaaat agcctgactt gtaatgaata
     1261 atgaatattt cttgatattt aatgtatagg acatttattt atactcaata aatatttttc
     1321 aaaaggaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
