LOCUS       NM_001109533            2531 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus charged multivesicular body protein 1B (Chmp1b),
            mRNA.
ACCESSION   NM_001109533 XM_001067633
VERSION     NM_001109533.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2531)
  AUTHORS   Kipper S, Hamad S, Caly L, Avrahami D, Bacharach E, Jans DA, Gerber
            D and Bajorek M.
  TITLE     New host factors important for respiratory syncytial virus (RSV)
            replication revealed by a novel microfluidics screen for
            interactors of matrix (M) protein
  JOURNAL   Mol Cell Proteomics 14 (3), 532-543 (2015)
   PUBMED   25556234
REFERENCE   2  (bases 1 to 2531)
  AUTHORS   Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE and Hanson PI.
  TITLE     Structure of cellular ESCRT-III spirals and their relationship to
            HIV budding
  JOURNAL   Elife 3, e02184 (2014)
   PUBMED   24878737
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2531)
  AUTHORS   Lee S, Chang J, Renvoise B, Tipirneni A, Yang S and Blackstone C.
  TITLE     MITD1 is recruited to midbodies by ESCRT-III and participates in
            cytokinesis
  JOURNAL   Mol Biol Cell 23 (22), 4347-4361 (2012)
   PUBMED   23015756
REFERENCE   4  (bases 1 to 2531)
  AUTHORS   Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M and
            Stoorvogel W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 2531)
  AUTHORS   Morita E, Colf LA, Karren MA, Sandrin V, Rodesch CK and Sundquist
            WI.
  TITLE     Human ESCRT-III and VPS4 proteins are required for centrosome and
            spindle maintenance
  JOURNAL   Proc Natl Acad Sci U S A 107 (29), 12889-12894 (2010)
   PUBMED   20616062
REFERENCE   6  (bases 1 to 2531)
  AUTHORS   Bajorek M, Schubert HL, McCullough J, Langelier C, Eckert DM,
            Stubblefield WM, Uter NT, Myszka DG, Hill CP and Sundquist WI.
  TITLE     Structural basis for ESCRT-III protein autoinhibition
  JOURNAL   Nat Struct Mol Biol 16 (7), 754-762 (2009)
   PUBMED   19525971
REFERENCE   7  (bases 1 to 2531)
  AUTHORS   Bajorek M, Morita E, Skalicky JJ, Morham SG, Babst M and Sundquist
            WI.
  TITLE     Biochemical analyses of human IST1 and its function in cytokinesis
  JOURNAL   Mol Biol Cell 20 (5), 1360-1373 (2009)
   PUBMED   19129479
REFERENCE   8  (bases 1 to 2531)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   9  (bases 1 to 2531)
  AUTHORS   Stuchell-Brereton MD, Skalicky JJ, Kieffer C, Karren MA, Ghaffarian
            S and Sundquist WI.
  TITLE     ESCRT-III recognition by VPS4 ATPases
  JOURNAL   Nature 449 (7163), 740-744 (2007)
   PUBMED   17928862
REFERENCE   10 (bases 1 to 2531)
  AUTHORS   Tsang HT, Connell JW, Brown SE, Thompson A, Reid E and Sanderson
            CM.
  TITLE     A systematic analysis of human CHMP protein interactions:
            additional MIT domain-containing proteins bind to multiple
            components of the human ESCRT III complex
  JOURNAL   Genomics 88 (3), 333-346 (2006)
   PUBMED   16730941
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473971.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001067633.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2531
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..2531
                     /gene="Chmp1b"
                     /note="charged multivesicular body protein 1B"
                     /db_xref="GeneID:689364"
                     /db_xref="RGD:1593500"
     exon            1..2531
                     /gene="Chmp1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..732
                     /gene="Chmp1b"
                     /note="chromatin modifying protein 1B"
                     /codon_start=1
                     /product="charged multivesicular body protein 1b"
                     /protein_id="NP_001103003.1"
                     /db_xref="GeneID:689364"
                     /db_xref="RGD:1593500"
                     /translation="MEKHLFNLKFAAKELNRSAKKCDKEEKAEKAKIKKAIQKGNMEV
                     ARIHAENAIRQKNQAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKT
                     MNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLD
                     LNMELPQGQTGSVGTSVASAEQDELSQRLARLRDQV"
ORIGIN      
        1 agagtttgac gtcactgtct gcgccgcata gcgtagatac aggaagtgag accaaaacaa
       61 agaagcgccg gccgggagtg gacctccttg cgccggtgta cctgctgctt cgctccggcc
      121 caccccgcga ccttgtccaa catggagaaa catctgttca acctgaaatt cgcggccaaa
      181 gaactgaaca ggagtgccaa aaaatgcgac aaggaagaaa aggccgaaaa ggccaaaatt
      241 aaaaaggcca ttcagaaggg caacatggaa gttgcgagga tacacgccga aaatgccatc
      301 cgccagaaga atcaagcggt aaacttcttg agaatgagtg cacgagtgga tgcggtcgct
      361 gccagagtcc agactgcagt gacgatgggc aaagtgacca agtccatggc gggtgtggtt
      421 aagtcgatgg acgcgacgtt gaaaactatg aatctggaaa agatctcagc tttgatggac
      481 aaattcgaac accagtttga gaccctggac gtccagactc agcaaatgga agacacgatg
      541 agcagcacga cgacgttgac cactccccag aaccaagtgg atatgctgct ccaggaaatg
      601 gcagatgagg cgggcctcga tctcaacatg gagctgcctc agggccagac cggttccgtg
      661 ggaacgagcg tagcttcggc tgagcaagat gaactgtccc agagattggc ccgccttcgg
      721 gatcaagtct gaccgccgaa cgagtccgag atttcctttg gacgtgctct ctgtgtttta
      781 tagagagatg tcctagaatt gtgccagaat gccgaacagt cttctaagaa cctacagccc
      841 cctccagata acgctaagaa attccagttt ttctccactt ctaactggat tttaaaactc
      901 tttatagctt atgatgatgt gtatttttat agctgccttt taacagaact ggttcatttg
      961 ctctacataa atctagaaaa aaaatcagca gaactctagc tctcgtgtat tccgttttca
     1021 cttaaaatta tcagactgaa gtttagtgtg gttgatggta catagactga caagaagcgc
     1081 ataaaaatga aaggaggaat cggtacttag tttagtaaca aatgtgtaaa cacttcaact
     1141 tactcggtgg gaaatacttt ctgtatatca tttggttttc tttgtttttg ctgtcaaaga
     1201 acgactgcaa ttgacttaat ttattctcat aacttatact aaagttatct tagaagatta
     1261 ttgcagaata ctctttacat tctgttagtt catgtattaa tggagtttgt gtaactggga
     1321 aaaaatgcca agtaacttcg tttattatca ggaaaaatta aatgtttttg tttatattct
     1381 ttaactctag ccaagagttc tgaagacttc agcttaagat agtttctaat taaaataatc
     1441 tctagttgtt ttctaatgaa agtcaacctt taatagtttc ctgatcaaaa tcatgttcat
     1501 caacatgaca gtcctattac atgccaaaca ttgccaaaga actgctgatt tggtctggct
     1561 aagccctggg actgtaatta taggttttgt ttttatttaa taaccaaaca tataaataaa
     1621 attagaacag cattttttaa gttctatttg tattattttg tcttaaaaca acaactcttt
     1681 taaagcctca aaaagcacaa cttaatgcta tagatatata aaacttaaat gtacatttag
     1741 ccagctagaa gtctagaaga aaggaattga gatgggatta gaaggaaaga gagaggctga
     1801 aagccaccag ccgcatctgc cttcctttat agcctcgggt gtgaagcaaa gcaactccca
     1861 cttttcttcc tgtcctcaaa tcacagagaa caacctgtgt ttgcttggca tatatattaa
     1921 cctaagttaa gtacttacaa agttcccttt tatccagttt ccccttttcc tgagtttcat
     1981 tttgtttcgt tttttccgtt aagagtattg caatgtttca gacaaagagc ctctgtaaaa
     2041 ctctgaaaaa ttcattacta gagtatggtt tcccaggtaa atagtgttta atgaaaaaag
     2101 tataagagtc cactgatgag tattggttct cagagttaag gagtgtgtgt gatgtatgtg
     2161 tgtatgtgtg tacatgaaca tgcatatata cacatttttt catgtctgcc ctaagggaca
     2221 tctaactgcc ccatgtcctc tctcagtggt cctttagcag acatgtgact tcttatatac
     2281 acagttatgc taactcgggt gtgtaatgaa tacagtatgc cttaatcctt tttcctggaa
     2341 aaccttggtt aattacagct ttaaaaaaaa tagctcagga ttgactcctt ggtaaatttt
     2401 atactgcaag taactccatc acattatatt ttgtgagatt gaagtatgca atatatgctt
     2461 aagctttctt gaagtatgtt catttcatac cacatgaatg tacatttata tgatccataa
     2521 acattatttt c
//
