LOCUS       NM_001107797           10472 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chromodomain helicase DNA binding protein 6
            (Chd6), mRNA.
ACCESSION   NM_001107797 XM_001068943 XM_230814
VERSION     NM_001107797.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10472)
  AUTHORS   Hayes,J.D. and Dinkova-Kostova,A.T.
  TITLE     The Nrf2 regulatory network provides an interface between redox and
            intermediary metabolism
  JOURNAL   Trends Biochem Sci 39 (4), 199-218 (2014)
   PUBMED   24647116
  REMARK    Review article
REFERENCE   2  (bases 1 to 10472)
  AUTHORS   Lutz,T., Stoger,R. and Nieto,A.
  TITLE     CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of
            mRNA synthesis
  JOURNAL   FEBS Lett 580 (25), 5851-5857 (2006)
   PUBMED   17027977
REFERENCE   3  (bases 1 to 10472)
  AUTHORS   Nioi,P., Nguyen,T., Sherratt,P.J. and Pickett,C.B.
  TITLE     The carboxy-terminal Neh3 domain of Nrf2 is required for
            transcriptional activation
  JOURNAL   Mol Cell Biol 25 (24), 10895-10906 (2005)
   PUBMED   16314513
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474005.2.
            
            [WARNING] On Oct 22, 2024 this sequence was replaced by
            NM_001107797.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001068943.1, XM_230814.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760389, SAMEA5760433
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..10472
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..10472
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /note="chromodomain helicase DNA binding protein 6"
                     /db_xref="GeneID:311607"
                     /db_xref="RGD:1310465"
     exon            1..88
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            89..143
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..8207
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /EC_number="3.6.4.12"
                     /note="ATP-dependent helicase CHD6"
                     /codon_start=1
                     /product="chromodomain-helicase-DNA-binding protein 6"
                     /protein_id="NP_001101267.1"
                     /db_xref="GeneID:311607"
                     /db_xref="RGD:1310465"
                     /translation="MKMKIQKKEKQLSKLRALNHSPMSDASVNFDYKSPSPFDCSPDQ
                     GENIEEAANHCLPQKDFYTTEEEADTLFSRKLMSHNGMEDNGGRGTGVKKKRKKKEPG
                     EQEGTKASKDREPKPKRKREPKEPKEPRRAKEPKRAKEPKEAKQKDGVKKPRKPREAS
                     GTKEGKEKRSCTDCGPRTKPKKASKDQGPTPVERKKKGKRKNETTVESLELDQSLPNP
                     SLQSPEEPSESADSQKRRSGRQVKRRKYNEDLDFKVVDDDGETIAVLGAGRTSALSAS
                     TLAWQAEEPPEDDANIIEKILASKTVQEVHPGEPPFDLELFYVKYRNFSYLHCKWATM
                     EELEKDPRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIEIDRILEVAHTKDAETGE
                     EVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQILPEVKPVERPASDAWQKLET
                     SREYKNSNRLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIAFLSEIFVRGIH
                     GPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGV
                     FKFHVVITTFEMILADCPELKKIHWSCVVIDEAHRLKNRNCKLLEGLKLMALEHKVLL
                     TGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRL
                     KDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMEL
                     RKCCNHPYLINGAEEKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIAGG
                     HKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLL
                     CTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYER
                     EMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSK
                     FCEEDIDQILQRRTHTITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAE
                     LDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSELDSDSDERPTRSRRLSDKA
                     RRYLRAECFRVEKNLLTFGWGRWKDILTHGRFKWPLNEKDMEVICRALLVYCVKHYKG
                     DEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTKNQLLLPELKTADWLA
                     TCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYYLKAEILGEAADKAFEGTPARELDVL
                     LPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKVGMPDEKSLS
                     AEQGVTDGTSDIPERGNIDKEDSAEDKVDGLQKQTASPSDGSDGIFGEKKDDSQAVSS
                     ALTARLRRLVTIYQRCNRKELCRPEILGPGNQGYWVQEEVFRRTSDMDLINKEAQKRW
                     TRREQADFYRTVSSFGVVYDQEKEAFDWTQFRAISRLDKKSDENLEHYFHSFVAMCRN
                     VCRLPTWKDDGPPDASIYVEPITEERAAKTLYRIELLRKVREQVLTCPQLHERLQLCR
                     PSLYLPVWWECGKHDRDLLIGTAKHGLNRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQ
                     APGSLCCLYQGNSKLYESLTYTPMSRTSESLESEPENLVKMDSRDDHLCLPEAGLPDI
                     TCENFVSKVQEVISLDHDESLLPESLENMMYGKTGLSQEPRSFQEAPSTNMQSRKKTV
                     TVSASRDESCQLPGIEAEITSASSLMSSLEAGVAKMNIKNGKHLLVSISEEGEPCCSE
                     TGRSPESRGRLEARCLASPTLDTGHESGFVDLCSLSVYDSKRNFSSDQQLIDLLENKS
                     LENKLILNQSDEEEEENEKETLAIVASTTEKPAVLDFTQPTASIPRGKNLSFHQDEAK
                     KGRLEVGSKTPGPQRAFPPSANQCHCKHIERWAHGLGSEESEGEKPKAYEPDPYRSKA
                     NNTTVEGEPAIIPTEPFKLKHELLKEPWKESSEGGKSFSMYVPEGSEPKSEEMDFENK
                     DDYEKDGACHSQDYPGKYSEEESKSSASGIAGDLGEEAQEVRAPTIAQLLQEKTLYSF
                     SEWPKDRVIINRLDNICHVVLKGKWPCSHQYEPSGALPTPVLSSSAGSRSSLSEPEAT
                     EHSFSNGAALAAQIQKESFLAPVFTKDEQKHRRPYEFEVERDAKARSLEEYSASHGRP
                     PIVLNGWHGESAIDLSCSSEGSPGATSPFPVSASTPKIGAISSLQGALGMDLSGILQA
                     GLIHPVTGQIVNGSLRRDDAAMRRRRGRRKHIEGGMDLIFLKEQTLQAGILEVHEDAG
                     QTTLNTTHPEGPGAASSASEPTAAASSQAEKAVPSKSLLDWLRQQADYSLDVPGFGAS
                     FSDKPKQRRPRCKEPGKLDIGSLGGEERVSAVPKEPGLRGFLPESKFNHTLAEPVLRD
                     AGPRRRGRRPRNELLKAPAIVADSPSGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTG
                     LVGFPAGFATMPTGEDVKNTLSMLPMMLPGMATVPQMFGVGGLLNTPMATTCTTTASA
                     SLASTKSGASATEKTTEDELSGRDVKADSLVEDKPGPSPFSDQSEPTITTSSPVAFNP
                     FLIPGVSPGLIYPSMFLSPGMGMALPAMQQGRHSEMAGLETQKRKKKKTKGDNPTPEP
                     ASVCEREPGSDQNCTESSVTVSPEREHVAQAREEGLKDSNDDTN"
     exon            144..661
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            662..809
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            810..959
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1022
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1081
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1199
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1286
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1421
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1543
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1787
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1964
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2108
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2109..2364
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2575
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2771
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2936
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2937..3116
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3117..3227
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3228..3430
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3431..3630
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3631..3790
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3791..3880
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3881..3984
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3985..4114
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            4115..4175
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            4176..4236
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            4237..4414
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            4415..4623
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            4624..6195
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            6196..6347
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            6348..6554
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            6555..7007
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            7008..7199
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            7200..7319
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
     exon            7320..10472
                     /gene="Chd6"
                     /gene_synonym="CHD-6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggttaggg tgtccttgca gggtgtctga gctaaacttc accaaataat agctgtttgt
       61 attttggctg ctgcaggagc cattttagaa ataaatattt ccctaagttg atgaaaatga
      121 aaatacagaa gaaagagaag cagttgtcca agttaagagc tttgaatcac tccccaatgt
      181 cggatgcctc cgttaacttt gactacaaat caccatcacc attcgattgc agtcctgatc
      241 agggagagaa cattgaagaa gctgccaatc attgtctgcc ccagaaggac ttctatacta
      301 ctgaagagga agctgacacc cttttttcta ggaagttgat gtcccataat gggatggagg
      361 ataatggagg cagaggcact ggagtaaaga agaaacggaa gaaaaaggag ccaggggagc
      421 aagaggggac aaaggctagc aaggacaggg agcctaagcc aaagaggaaa cgagaaccta
      481 aagagccaaa agaacccaga agggccaagg agcctaagag agccaaggag cccaaggagg
      541 caaagcagaa agacggcgtg aagaagcccc ggaagccccg ggaggcctcc ggtaccaagg
      601 agggtaaaga gaagaggagc tgcactgact gtggacccag gacaaagccc aagaaggcca
      661 gcaaggatca aggaccaacc ccagtggaga gaaagaagaa aggaaaaagg aaaaatgaaa
      721 ccaccgtgga gagtttagag ctggaccaga gtcttccaaa cccatctctg cagagtcctg
      781 aggagcccag tgagtctgca gacagccaga aacggcgctc aggacggcaa gtaaagcgta
      841 gaaaatataa tgaggacctg gacttcaagg tcgtggacga tgatggggaa acaatcgctg
      901 ttctgggagc aggccggaca tctgcactct ctgcttccac cctggcctgg caggctgagg
      961 agcctccaga agatgatgca aacatcattg agaaaatcct ggcatccaag actgtccagg
     1021 aggttcaccc aggagaacct ccattcgacc tagagctttt ctacgttaag tatagaaatt
     1081 tctcctattt acattgtaag tgggccacaa tggaagagct ggaaaaggat ccccgcatcg
     1141 ctcagaagat caagcgcttt aggaacaaac aggcccagat gaagcatatt tttactgagc
     1201 ctgatgaaga cttgttcaat ccagattata tagaaattga tcgtatcttg gaggtggccc
     1261 acaccaagga tgcagaaaca ggggaggaag tgacccatta cctggtaaaa tggtgctctc
     1321 tgccgtatga agaaagcaca tgggagctag aggaagatgt ggatcctgca aaagtgaaag
     1381 aatttgaatc tctacaaatt ctccctgaag ttaagcctgt ggaacgacct gcctctgatg
     1441 catggcagaa actggagacc tctcgtgagt ataagaacag taaccggctg cgggagtacc
     1501 agctcgaggg catgaactgg ctgcttttca actggtacaa cagaaaaaac tgtattttgg
     1561 ctgatgaaat gggcctaggg aaaaccatcc agtccatcgc attcctttca gaaatctttg
     1621 tcaggggaat ccatggcccc tttctcatca ttgcccctct ttccaccatc actaactggg
     1681 agcgagaatt ccggacatgg acagagatga atgctattgt gtaccacggc agccagatca
     1741 gcaggcagat gatccagcag tacgaaatgg tatacagaga tgcacagggg aacccccttt
     1801 caggagtttt caagttccat gtcgtcatca caacattcga gatgatcctg gcagattgcc
     1861 cagagctgaa gaagattcac tggagctgtg tggtaattga tgaggcccac agattgaaga
     1921 ataggaactg taaacttctg gaagggttaa agctcatggc cctggaacac aaggtgctac
     1981 tcacaggaac gcccttgcag aactcagtgg aagagctctt cagtttgctt aactttctgg
     2041 agccctcaca gtttccttca gagactgctt tcttagagga gtttggtgat ctcaaaacag
     2101 aagaacaggt aaagaaattg cagtctatcc taaaaccaat gatgcttcgg cgcctgaaag
     2161 atgatgtgga gaagaacctt gctcccaagc aggagaccat cattgaagta gaactgacca
     2221 atatccagaa aaagtactac cgtgctatcc tagagaaaaa cttctccttc ctgaccaaag
     2281 gtgcaaatca gcacaacatg cccaacctta tcaatactat gatggagctg agaaaatgct
     2341 gcaaccaccc ctacctgatc aatggggcag aggaaaagat tctggaagat ttcaggaaag
     2401 cccacagctc tgaagcctct gacttccagc tacaggccat gatccaggcg gcggggaagc
     2461 tggtgctcat tgacaagctt ctccccaagc tcattgctgg cggccacaaa gtgctcatct
     2521 tctctcagat ggtgcgctgt ctcgacatcc tggaggacta tctcatccag agacgataca
     2581 cctatgagcg aattgatggg cgagtacggg gaaacctgcg ccaggcagcc atcgaccggt
     2641 tctgtaagcc agactcagac cgctttgtct ttcttctgtg caccagagcg ggaggcctgg
     2701 gaatcaatct cacagctgct gatacctgca tcatatttga ttctgactgg aacccacaaa
     2761 atgacttgca ggctcaggcc cggtgtcatc gtataggcca gagcaaagcc gtaaaggtat
     2821 atcgcctaat cactcgaaac tcctatgagc gggaaatgtt tgacaaggcc agcctgaagc
     2881 tgggcctgga caaggctatt cttcaggaca tcaacagaaa gggcagcacc aatggagtgc
     2941 agcagctctc aaaaatggaa gtagaagatt tgctccggaa aggtgcttat ggagctttaa
     3001 tggacgagga ggatgaaggc tccaagttct gtgaagagga catagaccag attctgcaga
     3061 gacggaccca caccatcacc atccagtcag aagggaaggg ctccactttt gccaaggcta
     3121 gttttgtggc ttcaggaaac agaacagata tttccttgga tgatcccaat ttttggcaga
     3181 aatgggctaa aatagctgag ttagacactg aagcaaataa tgaaaaggaa agcttagtga
     3241 ttgaccggcc acgggtgagg aaacagacca aacactacaa ctcatttgag gaggatgagc
     3301 ttatggagtt ctcagagtta gacagtgact cggatgaaag gcccacacgg tccaggcgcc
     3361 tcagtgacaa agccaggcgc tacctccgcg ctgagtgctt ccgagtagag aagaacctgc
     3421 tcacctttgg ctggggccgc tggaaggaca tcctgactca cggacgattc aagtggcccc
     3481 tgaatgagaa ggatatggag gtgatttgcc gggctctgct agtatactgc gtgaagcatt
     3541 acaaaggaga tgagaaaatc aagagtttta tttgggaact aatcacacct tccaaagacg
     3601 gacaggttca gaccctccag aaccactcag gcttgtctgc cccagtcccc agagggagga
     3661 aaggaaaaaa gacgaaaaac cagctgttgc tcccagaact gaagactgca gactggttgg
     3721 ccacttgcaa tcccgaggtg gtcttacatg atgatgggta caaaaaacac ctcaagcagc
     3781 actgtaacaa ggtgcttttg agagtccgga tgctgtacta cctaaaagct gaaatattag
     3841 gagaagcagc tgataaagcc tttgagggaa ctcctgccag agagctggat gtccttctgc
     3901 ccgacattga ctatgtggag atcccagtag attggtggga tgctgaagct gataagtccc
     3961 ttctcattgg tgtgttcaag cacggttatg agaggtacaa tgccatgcgg gctgacccag
     4021 cactctgttt cctggagaaa gtcggcatgc ctgatgagaa gtccctttct gcagagcagg
     4081 gtgttacaga tggaacctca gacattcctg aaagaggcaa catagataaa gaagacagtg
     4141 ctgaggacaa ggtagatggt ctccagaagc aaacggcgag tcccagtgat ggaagtgatg
     4201 gcatttttgg tgaaaagaag gatgacagcc aggcagtttc ctctgccctc actgctcgac
     4261 taaggcgtct ggtcactatt taccagcgct gcaaccgcaa ggagctgtgc agacctgaaa
     4321 tcctaggccc aggtaaccaa ggatactggg ttcaggagga ggtgttcagg agaacttcag
     4381 acatggacct catcaacaag gaagcccaaa aaaggtggac tagaagagaa caagccgact
     4441 tctatagaac cgtgtcttcc ttcggtgttg tgtatgacca ggaaaaggaa gcctttgact
     4501 ggacgcagtt ccgcgccatt tctcgcttgg acaagaagtc agatgagaac ctggagcact
     4561 attttcatag ttttgtagcc atgtgtcgga atgtgtgtcg tcttcccaca tggaaagatg
     4621 atggtccccc tgatgccagc atctatgttg agcccatcac cgaggaacgg gcagcaaaga
     4681 ctctgtaccg cattgaacta ctgaggaaag tccgtgagca ggtgctcacg tgtcctcaac
     4741 tgcatgagcg cctccagctt tgcagaccca gcctctacct cccagtctgg tgggaatgtg
     4801 ggaaacatga tcgagacctg cttattggca ccgccaaaca tgggctcaac cgcactgact
     4861 attacatcat gaatgacccc cagctgtcct tcctagatgc ctatagaaac tatgcccaac
     4921 acaaaagaac tgacacccag gctcctggaa gtctctgttg cctttaccag ggcaattcta
     4981 aactatatga gtctcttact tatacgccaa tgagtaggac ttcagagtct cttgaaagtg
     5041 agccagagaa tctggtaaaa atggacagca gggacgatca tctctgcctg cctgaggctg
     5101 gtctgcctga cataacctgt gaaaactttg tttccaaagt tcaggaagtc atttctctgg
     5161 accatgatga aagcttgctg ccggagtctt tggagaacat gatgtatggc aagacaggac
     5221 tcagccagga gccacgatct tttcaggagg ccccaagtac caacatgcag tccaggaaaa
     5281 agactgtcac cgtctcagcc agcagagacg agagctgcca gcttcctggt attgaggcag
     5341 aaattacttc agcttcctct ctcatgagca gcttagaagc aggagtggcc aagatgaata
     5401 ttaaaaatgg aaagcatttg ttggtatcga tctcagaaga aggggagccc tgctgcagcg
     5461 agacagggcg gagccctgaa agcagaggcc gcctggaggc cagatgctta gcttccccta
     5521 ccttagatac agggcacgaa agtgggtttg tagatctgtg cagccttagt gtctatgact
     5581 ccaaaagaaa cttctcatca gatcagcaat taattgattt attagaaaac aagagtttag
     5641 aaaataagtt gattttgaat cagagtgatg aggaagagga agaaaatgag aaggaaacct
     5701 tagccatagt agccagcacc acagaaaagc cagcggtctt agatttcacc cagcccactg
     5761 caagcatccc aaggggaaag aacctcagct tccaccaaga tgaagccaag aaaggaaggc
     5821 tggaggtggg aagcaagact cctggaccac agagggcctt tcctccctca gccaatcagt
     5881 gccactgcaa acacattgaa aggtgggcac atggcctggg gagtgaggaa tctgaaggag
     5941 agaaacccaa ggcttacgag ccagacccgt acagaagcaa agccaataat accacagtgg
     6001 aaggtgagcc tgctattatt ccaacagagc catttaaact gaagcatgag cttttaaaag
     6061 aaccgtggaa agaaagttca gaggggggga agagtttctc catgtatgtt cccgagggaa
     6121 gtgaacccaa atcagaagaa atggattttg agaataaaga tgattatgag aaggatggag
     6181 cctgccacag tcaagactac ccaggcaaat actctgagga ggagagtaag agttcggcat
     6241 caggcattgc aggagacctt ggggaagagg cacaggaagt gcgggctccc accattgctc
     6301 agctcctgca ggaaaaaacc ctctattcct tctcagagtg gccaaaggac cgtgtgataa
     6361 ttaaccgcct agataatatt tgccatgtgg tgttaaaggg gaagtggccc tgcagccacc
     6421 agtatgagcc ctcaggtgca ctgcccacgc cagtgttatc cagcagtgca ggttctcgaa
     6481 gcagcctctc agagccagaa gcaaccgaac acagcttcag caatggtgca gcattggcag
     6541 cccagatcca aaaggagagc ttcttagccc cagtattcac aaaagatgaa caaaagcaca
     6601 gacgtcccta tgagtttgag gtggaaaggg atgccaaagc tcggagccta gaagaatact
     6661 ctgccagcca tgggcgtccc cccattgtcc tcaatggctg gcatggggag tcagctatag
     6721 acctctcctg ctcatcagag gggtctccag gagccacatc tcctttccca gtaagtgcca
     6781 gcacccctaa gattggtgct atcagctcac ttcaaggagc cctcggtatg gacttgtctg
     6841 gaattctgca agctggccta atccacccag taactggaca gatcgtcaat ggaagcctca
     6901 ggagggatga tgctgccatg agaaggcgaa gagggagacg aaaacatatt gaaggaggga
     6961 tggacctcat ctttctgaag gagcaaacac ttcaggctgg aatcttggaa gtccatgaag
     7021 atgcaggaca gactaccctg aacaccacac accctgaagg gccaggagct gcttcctcag
     7081 cttctgagcc aacagcagca gccagcagcc aggctgagaa agctgttccc agcaagagcc
     7141 tacttgactg gctgcggcag caggctgact actccttgga tgttcctggc tttggggcaa
     7201 gtttttcaga caaacccaag cagaggagac cacgctgcaa agaacctgga aaattagaca
     7261 tcggctctct aggtggagaa gagagggttt ctgctgtccc caaggagcca ggactaaggg
     7321 ggtttctccc agaaagcaaa ttcaatcaca ccctagccga acctgtgctt cgagatgcag
     7381 gcccccgcag gagggggagg cggcctcgga atgagctcct aaaagctcca gccattgtag
     7441 cagactctcc ttctggaatg ggaccactgt tcatgaatgg gctgattgca gggatggacc
     7501 tggtaggatt gcagaatgtg agaaatattc caggcattcc tctcactggg ctggtgggct
     7561 tcccagctgg ttttgccacc atgcctactg gtgaagacgt caaaaacacc ctgagcatgc
     7621 tgcccatgat gctgccaggc atggccacag tgccccagat gtttggtgtt ggcggactcc
     7681 tcaacacacc catggcaacc acctgcacga ccactgcatc agcgtctctc gcaagcacaa
     7741 aaagtggtgc ctcagccact gaaaaaacta cagaggacga gctgagtggc cgtgatgtga
     7801 aagcagacag tctggtcgaa gataagcctg gccctagtcc attttctgat cagtctgaac
     7861 ccacaataac tacaagtagt cctgtggctt tcaacccatt tctcatccca ggagtatctc
     7921 ctggactcat ctacccctcc atgtttctct cccctggcat gggcatggct ctgccagcca
     7981 tgcagcaggg tagacactca gagatggccg gtctagagac ccagaagagg aaaaagaaga
     8041 aaacaaaggg ggacaacccc accccagagc ctgcttctgt gtgtgagagg gagccaggca
     8101 gtgatcagaa ctgcaccgag tccagtgtca ctgtgtcccc agagagagaa cacgtggcac
     8161 aggccaggga agaggggctc aaagactcta acgatgatac caattagaac tttttcattt
     8221 aagaaattat tgtgacttgt aagtttctta tcccataaag gtttgttact tccctcactt
     8281 ccccttcata agaacctgtg ttttcatcag taatattacc tacctaccta atttcctgtc
     8341 tgaggactat ggtaacatgt taatagttgc agggtcttgc cacttcgtta gataagtgtc
     8401 acctgcctag tctaggagac acagaattct ttattttatc cggttcattc cagcaatcac
     8461 agttgataca gagcttggtg acatgccccc ttctccttct ctttcaagtc ccactctcct
     8521 gaggaagaaa tggcagaaga aagctggcta gggattcact gtggggccaa agagcaaaga
     8581 cgaaagtgag caactgaata aggaggacag gtcgaggaaa ccaaaaggca cacaatagga
     8641 agtgtccatg tgtactttcg tagttcaggc gtccctattt tatcatggtc actgagtagt
     8701 ttagtctaca gcatgtaaac caatggctca agtgcacaga ctgatggctg ctttcaaaga
     8761 gggaccttcc aggtagtaat agagttcccc ctcttaagca agaagaaata ctggccagct
     8821 aggcagtaca cctgtcatct ctgccgaatc tgagacactt cagcgcctcg agttactgca
     8881 gcaactggga gggcgctgct cagggcccat gggtgctgct ggcactcatg tcccctctta
     8941 agaaacctgc tggacttcat tttgtgctct tttcacccag agccaggcct tttggagcct
     9001 aggaaggtaa tcactcagca cttgctagat tctgccgtca gcctagcgtg tcaaaacacc
     9061 atcttttaca ttgcaactgt gaagttttgt ccctctccat tttctctcta ctcggactgt
     9121 atcttaagag ttgggcccaa attccaaatt gtcagtcagg caaggttctg ttagtcagca
     9181 gcgtgctctc tccagctctg tgttgaaaaa ctgagcaaga gagcccactt ggctgcgctt
     9241 ctgcttccgg ttttctttcc cctcaccctc acatcatgtc cctcctgatg gtctcctccg
     9301 tggacagctc ctgctgagac ttgaaccagc caagcccagt tctctagggc acaggctcag
     9361 gggctggaca ggtggtgggt gtcccgagta ccaggttcac ttcggtgtca cagttgactg
     9421 tgtttatttt tactgtttct gttacagttt tgctaattta tcagaaggtc cgaaagtttg
     9481 gcatgctatt tcagtttgca ttatttattt atgatgattt ttgtcattgt cttttataca
     9541 tttggggtta taaattatgt aaatgttaaa atgagcatct caaagaagtc tgttaaattg
     9601 tgaccgggaa aaaaagccaa tcaggtgtat tttcaaaacg gagagtccca gttttatgaa
     9661 tcatagatat aaactagaaa ttctattact gatctataag aaagaatcca agaactgaat
     9721 aaatgatatt taatggcgtc tttgtagtgt agaaggtctg tgatgctgat aacagatttc
     9781 ttagaaatgc tgttcactgt tgaactaaca ttctgctcag ttctgcctcc agtggaagca
     9841 gacagggctt ttcagctgtt aaatcctaaa aatcaatata atttatttat gtaaaagaaa
     9901 cacgcaatca atatattttt gaacctttta agtactaatt ttctttttat caagtagaaa
     9961 aaaatgtatt tgccctaaat ccttaaaata caaatgctat ataaaaactc ctgtatcttg
    10021 aaagccttac tgcaaatgag cattatagac acccagcaga gtctgctctt cctgttgtct
    10081 cctgtgttgt ttcatgtgga gagctcctct ccccagctcc cacttaaacc tccgagtagg
    10141 tcacagggtt cagtgtggac ctggcttaac caccagcatg cgcacccctt gctatatctt
    10201 accaaacctg tatgttagct cttgggtgtt taggcttctg ttgactgctg ttgtgatact
    10261 gtttgcaaaa tgaacttgac actgtggact atttgctctg taagacatac gtgctgctta
    10321 ggattatttt aacgttccga gagcaaaagc caaatttaaa ctctcttcag caaacttgag
    10381 cctcttcatc taattccatg tcactcacag ccataacttc ccttggtcat tcttcaccca
    10441 tgtctcacgt aataaattgt ctgtggtctt ga
//
