LOCUS       XM_006237396            6701 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus chromodomain helicase DNA binding
            protein 4 (Chd4), transcript variant X1, mRNA.
ACCESSION   XM_006237396
VERSION     XM_006237396.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006237396.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006237396.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6701
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6701
                     /gene="Chd4"
                     /note="chromodomain helicase DNA binding protein 4;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 89 ESTs, 3 long SRA reads, 2
                     Proteins, and 98% coverage of the annotated genomic
                     feature by RNAseq alignments, including 231 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:117535"
                     /db_xref="RGD:620064"
     CDS             238..6108
                     /gene="Chd4"
                     /codon_start=1
                     /product="chromodomain-helicase-DNA-binding protein 4
                     isoform X1"
                     /protein_id="XP_006237458.1"
                     /db_xref="GeneID:117535"
                     /db_xref="RGD:620064"
                     /translation="MASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEDDPEEDLS
                     EAETPKLKKKKKPKKPRDPKIPKSKRQKKERLLLCRQLGDSSGEGPEFVEEDEEAALR
                     SDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGM
                     EDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFSTNNPF
                     KGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRKAKTKEGKGPNARRKPKG
                     SPRVPDAKKPKPKKVAPLKIKLGGFGSKRKRSSSEDDDLDVESDFDDASINSYSVSDG
                     STSRSSRSRKKLRTAKKKKKGEEEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAY
                     HMVCLDPDMEKAPEGKWSCPHCEKEGIQWEAKEDNSEGEEILEEVGGDPEEEDDHHME
                     FCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQKILIW
                     KWGQPPSPTPVPRPPDADPNTPSPKPLEGRPERQFFVKWQGMSYWHCSWVSELQLELH
                     CQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKNKDPKFAEMEERFYRYGIKPEWMMI
                     HRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEE
                     GRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFS
                     WAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWA
                     PDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELIT
                     IDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFH
                     LLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKADVFKNMPSKTEL
                     IVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAM
                     EAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEH
                     EGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDS
                     DWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVRPGLG
                     SKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQ
                     DETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRH
                     HYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRGVCGRPRPPPTGRSTRAVGPAHLPS
                     LPPDWQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVG
                     GNIEVLGFNARQRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRH
                     LCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPELAEV
                     EENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESTEGEKE
                     VKPTAPEVTVECAQPPAPAPAPASGPGPTPGPAPAPEDDKAPAEPPEGEEKVEKAEVK
                     ERAEEPMETESKGTTEVEKAEEKSAVDLTPIVVEDKEEKKEEEEKKEVLLQNGETPKD
                     LSDEKQKKNLKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAG
                     IINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQ
                     LRRAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQ
                     LEELLSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAPEPPPQQVAQQQ"
ORIGIN      
        1 ggcggggcct gtgcggtggg atttcccggc cggtgtttcg ggccctttaa gaggcgacgc
       61 cggagccgga gccattttcc ccccttcggc cgcggcgagg aggagccgga gcgggagtga
      121 caccggcgag acccagcgcg acctgaggcg gctctaggtg actcgggcca gtgtagaggg
      181 ccccaggccg caggcaggag cagctgggcc aattccctgg ccggggaacg gaaggggatg
      241 gcgtcgggcc tgggctcccc gtccccctgc tcagcgggca gtgaggagga ggatatggat
      301 gcacttctga acaacagcct gcccccaccc catccagaaa atgaggatga cccggaagag
      361 gatttatcag aagcagagac tccaaagctc aagaagaaga aaaaacctaa gaaaccccgg
      421 gaccctaaaa tccctaagag caagcgccag aaaaaggagc gtttactctt atgccggcag
      481 ctgggggaca gctctgggga ggggccggag tttgtggagg aggacgaaga ggcggctctg
      541 cgctcagaca gcgagggcag cgactatact cctggcaaga agaagaagaa gaagcttgga
      601 cccaagaaag agaagaagag caagtccaag cggaaggagg aggaggagga ggaagacgac
      661 gatgatgatt caaaggagcc taagtcgtct gcccagcttt tggaagactg gggcatggaa
      721 gacattgacc acgtgttctc agaggaggat taccgtacgc tcaccaacta caaggccttc
      781 agccagtttg tccgacccct aattgctgct aaaaacccca agattgctgt ctccaagatg
      841 atgatggtct tgggtgcaaa gtggagggaa ttcagtacca acaacccctt caaaggcagc
      901 tctggagcgt cagtggcggc tgcagctgca gcggctgtgg ctgtggtgga gagcatggtg
      961 acagctactg aagttgcccc tccccctccc cctgtggagg ttcctatccg caaggccaag
     1021 accaaggagg gcaaaggtcc caatgctcga aggaagccta aaggcagccc tcgagtgccg
     1081 gacgccaaga agcccaagcc caagaaagta gctcctctga aaatcaagct gggaggtttc
     1141 ggctccaaga ggaagagatc ctcgagtgag gacgatgact tagatgtgga gtccgacttc
     1201 gacgatgcca gtatcaatag ctattctgtc tcggatggct ctaccagccg cagcagtcgg
     1261 agccgcaaga agctccggac ggcgaagaag aagaagaaag gcgaggagga ggtgactgct
     1321 gtggatggtt atgagacaga ccaccaggac tattgcgagg tgtgccagca aggcggcgag
     1381 atcatcctgt gtgatacctg tccccgagcc taccatatgg tgtgcctgga cccagacatg
     1441 gagaaggccc ccgagggcaa gtggagctgc ccacactgtg agaaggaggg tatccagtgg
     1501 gaagctaagg aggacaattc tgagggtgaa gagattctgg aagaagttgg gggagaccca
     1561 gaagaggaag atgaccacca tatggaattc tgtcgagtct gcaaggatgg cggggaacta
     1621 ctatgctgtg acacctgccc ttcttcctac catatccact gtctgaaccc cccgctgcca
     1681 gagatcccaa atggcgaatg gctctgtccc cgctgtactt gtccagctct taagggcaaa
     1741 gtgcagaaga tcctaatttg gaagtggggc cagccaccat ctcctacacc agtgcctcgg
     1801 cctccagatg ctgatcctaa tactccatct cccaaaccct tggaggggcg gccagagagg
     1861 cagttctttg tgaaatggca aggcatgtct tactggcact gctcctgggt gtcagaattg
     1921 cagttggagc tgcactgtca ggtgatgttc agaaactacc agcggaagaa tgatatggat
     1981 gagccgcctt ctggggactt cggtggagat gaggagaaga gccgaaagcg aaagaacaag
     2041 gaccctaagt ttgcagagat ggaggagcgc ttctatcgct atggaataaa accggagtgg
     2101 atgatgatcc accggatcct caaccacagt gtggacaaga agggccacgt tcactattta
     2161 ataaagtggc gagacttacc ctacgatcag gcgtcttggg agagtgagga tgtggagata
     2221 caggactacg acctgttcaa gcagagctac tggaaccaca gggagttaat gaggggtgag
     2281 gaagggcgac ctggcaagaa gcttaagaag gtgaaattac ggaaactgga aaggcctccg
     2341 gagaccccaa ctgttgatcc cacagtgaag tatgagcgac agccggagta cctggatgcc
     2401 acaggtggaa ccctgcaccc ctaccaaatg gaaggcttaa actggctacg cttctcctgg
     2461 gctcagggta ccgataccat cctggctgat gaaatgggcc ttgggaaaac tgtgcagaca
     2521 gcagtcttcc tctattccct gtacaaggag ggtcactcca aaggcccctt cttagtgagc
     2581 gcgcctctgt ccaccatcat caactgggag cgagagtttg agatgtgggc tcctgatatg
     2641 tatgtggtga cctatgtggg tgacaaggac agccgtgcca tcatccggga aaatgagttc
     2701 tcctttgaag ataatgccat tcgtggtggc aagaaagcct cccgaatgaa gaaagaagca
     2761 tctgtgaaat tccatgttct gctgacatcc tatgagttga tcaccattga tatggccatc
     2821 ttgggttcta ttgactgggc ctgcctcatt gtggatgaag cccaccggct gaagaacaac
     2881 cagtctaagt tcttccgagt tttgaacggt tactcactcc aacacaagct gttgctaact
     2941 ggaactccat tacaaaacaa tctagaggaa ttgttccatc tgctcaactt tctcaccccc
     3001 gagaggttcc acaatttaga aggcttcttg gaagagtttg ctgacatcgc caaagaggac
     3061 cagattaaga aactacacga catgctgggg cctcacatgt tgcggcggct caaagctgat
     3121 gtcttcaaga acatgccctc caagacagaa ctgattgtgc gtgtggagct gagccctatg
     3181 caaaagaagt actacaagta cattctcact cggaattttg aggcacttaa tgctcgaggc
     3241 ggtggcaacc aggtttctct gctgaatgtg gtgatggatc ttaagaagtg ctgcaaccac
     3301 ccgtacctct tccctgtggc agcaatggag gcccctaaga tgcccaatgg tatgtacgac
     3361 ggcagtgccc tgatcagagc atctgggaaa ttgttgctgc tacagaagat gcttaagaac
     3421 ctgaaagagg gaggccatcg tgtgctcatc ttctcccaga tgaccaagat gttggacttg
     3481 ctagaggatt ttttagaaca cgaaggttat aaatatgaac gtattgatgg tggaatcact
     3541 gggaacatgc gtcaggaggc cattgatcgc ttcaatgcac cgggtgctca acagttctgc
     3601 ttcttgcttt ccactcgagc tgggggcctt gggatcaatc tggccactgc ggatacagtt
     3661 attatatatg actctgactg gaatccccat aatgacatcc aggcctttag cagagcccac
     3721 cgtattgggc agaataagaa ggtgatgatc taccggtttg tgactcgcgc atccgtggag
     3781 gagcgcatca cgcaggtggc aaagaagaag atgatgttga cacatttagt ggtgcggcct
     3841 ggcctgggct ccaagactgg ctcaatgtcc aaacaggagc ttgatgacat cctcaaattt
     3901 ggcaccgagg aactattcaa ggacgaagcc acggatggag gaggagacaa caaggaggga
     3961 gaagacagca gtgtcatcca ttatgacgat aaggccattg aacgactgct ggatcgaaat
     4021 caggatgaga ctgaagacac agaattgcag ggcatgaatg aatatttgag ttcattcaaa
     4081 gtggctcagt atgtggtacg ggaagaagaa atgggggagg aagaggaggt agaacgggaa
     4141 atcataaaac aggaagaaag tgtggatcct gactactggg agaaattgct gcggcaccat
     4201 tatgagcagc agcaagaaga tctagcccga aatctgggca aaggaaaaag aatccgtaaa
     4261 caggtcaact acaatgatgg ctcacaggag gaccgaggtg tgtgtggccg gccccgcccc
     4321 ccacccacgg gccgttccac tagagcagtg ggccccgctc atctgccctc tctccctcca
     4381 gattggcagg acgaccagtc cgacaaccag tccgattact cagtggcctc agaggaaggt
     4441 gatgaagact ttgacgaacg atcagaagct ccccgcaggc ccagtcgcaa gggcctgcgg
     4501 aatgataaag ataagccatt acctcctctg ctggcccgag ttggtgggaa tattgaagta
     4561 cttggtttta acgctcgtca gcgaaaagca tttcttaatg caattatgcg ctatggcatg
     4621 ccgcctcagg acgcctttac cactcagtgg cttgtgagag atcttcgagg caagtcagag
     4681 aaagaattta aggcttatgt gtcactcttc atgcgacatt tgtgtgagcc tggggcagat
     4741 ggggctgaga cttttgctga tggtgtccca cgagaaggcc tgtctcgcca acatgttctt
     4801 actagaattg gtgtcatgtc tctgattcga aagaaggttc aggagtttga acatgtcaat
     4861 gggcgctgga gcatgcctga actggctgaa gtggaggaaa acaaaaaaat gtctcagcca
     4921 ggttcaccct cgccaaagac tcctacacct tccacaccag gggacacaca gcccaatacc
     4981 cctgcacctg tgccacctgc tgaggatggg ataaaaatag aggaaaatag ccttaaagaa
     5041 gaagagagca cagaaggaga aaaggaagtt aaacctacag cccctgaggt gactgtggag
     5101 tgtgcacagc cccctgcccc tgcccctgcc cctgcctctg gccccggccc cacccctggc
     5161 cctgcccctg cccctgagga tgacaaggct cctgctgagc ctcctgaggg agaggagaaa
     5221 gtggaaaagg cagaggtgaa ggagagagca gaggagccca tggagacgga gtccaaaggt
     5281 actactgagg tggagaaagc ggaggagaag tctgcggtag acctgacccc gatcgtggtg
     5341 gaagacaaag aagagaagaa ggaggaagaa gagaaaaagg aggtgctgct tcagaacgga
     5401 gaaactccca aggatcttag tgatgagaag cagaagaaaa acctcaaaca gcgtttcatg
     5461 ttcaacattg cagatggcgg ttttaccgag ttgcactccc tttggcagaa tgaggagcgg
     5521 gcagccacgg tcactaagaa gacttatgag atttggcatc gccgccacga ctactggctg
     5581 ctggctggca ttataaacca cggctatgcc cggtggcagg acatccagaa tgacccacgg
     5641 tatgccatcc tcaatgagcc tttcaagggc gaaatgaatc gtggcaattt tctagagatc
     5701 aagaataaat ttctagctcg aagatttaag ctcttagaac aagccctggt gatcgaggag
     5761 cagctgcgaa gggcggctta cctgaacatg tcagaggacc cctctcatcc gtctatggcc
     5821 cttaacaccc gttttgctga ggtggagtgt ttggcagaaa gtcaccagca cctgtccaag
     5881 gagtcgatgg caggaaataa gccagccaat gcagtcttac acaaagtcct aaaacagctg
     5941 gaagaactgt tgagtgacat gaaggctgac gtgacacggc tcccagccac cattgcccgc
     6001 atccccccag ttgctgtgag gttacagatg tcagagcgga acattctcag ccgcctggca
     6061 aacagggcgc cagaacctcc cccacagcag gtagcccagc agcagtgaag acccagagtg
     6121 atgatccacc tctaccacta agcagtgacc ttcctcactt tctcttgtcc cggctgcccc
     6181 tgtgggccag agagaccctt gccttccttc tgcccgtctt ctgagttata aaggatcagc
     6241 cccgcctgcg cgcgcactgg gggcagggag ggagggagag gcaacggtgc ccctcctgct
     6301 ggagagacac gcagcagtag ctagcccagc gccgagcaag gagctggcgg gctggctgcc
     6361 ttctggaccc tggcttctcc ccaccgtgcg cctgttacaa actgttgtgg gttctgccag
     6421 gcttgaagaa aatgatctga atttcttcct ctttttggtt ttattttgtt ggtttacttt
     6481 gtgttttctc cttttggggg gtattcagag tgggccgggc ccctgggtga gacacagcta
     6541 cctctgttgg caccttttta ataccaggaa cccagcggct ccagccactg agcagctaaa
     6601 ataaagttgg aaaaaaaaaa aaaagaaaaa gaaccaaaag cataaaaaac cacagcaaat
     6661 ttcttgatga gaactgaaaa taaaagtttc cttgtatttt a
//
