LOCUS       NM_001107465            6568 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chromodomain helicase DNA binding protein 1
            (Chd1), mRNA.
ACCESSION   NM_001107465 XM_001056703 XM_238731
VERSION     NM_001107465.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6568)
  AUTHORS   Pilarowski,G.O., Vernon,H.J., Applegate,C.D., Boukas,L., Cho,M.T.,
            Gurnett,C.A., Benke,P.J., Beaver,E., Heeley,J.M., Medne,L.,
            Krantz,I.D., Azage,M., Niyazov,D., Henderson,L.B., Wentzensen,I.M.,
            Baskin,B., Sacoto,M.J.G., Bowman,G.D. and Bjornsson,H.T.
  TITLE     Missense variants in the chromatin remodeler CHD1 are associated
            with neurodevelopmental disability
  JOURNAL   J Med Genet 55 (8), 561-566 (2018)
   PUBMED   28866611
REFERENCE   2  (bases 1 to 6568)
  AUTHORS   Rodgers,M.J., Banks,D.J., Bradley,K.A. and Young,J.A.
  TITLE     CHD1 and CHD2 are positive regulators of HIV-1 gene expression
  JOURNAL   Virol J 11, 180 (2014)
   PUBMED   25297984
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6568)
  AUTHORS   Patel,D.J. and Wang,Z.
  TITLE     Readout of epigenetic modifications
  JOURNAL   Annu Rev Biochem 82, 81-118 (2013)
   PUBMED   23642229
  REMARK    Review article
REFERENCE   4  (bases 1 to 6568)
  AUTHORS   Huang,S., Gulzar,Z.G., Salari,K., Lapointe,J., Brooks,J.D. and
            Pollack,J.R.
  TITLE     Recurrent deletion of CHD1 in prostate cancer with relevance to
            cell invasiveness
  JOURNAL   Oncogene 31 (37), 4164-4170 (2012)
   PUBMED   22179824
REFERENCE   5  (bases 1 to 6568)
  AUTHORS   Grasso,C.S., Wu,Y.M., Robinson,D.R., Cao,X., Dhanasekaran,S.M.,
            Khan,A.P., Quist,M.J., Jing,X., Lonigro,R.J., Brenner,J.C.,
            Asangani,I.A., Ateeq,B., Chun,S.Y., Siddiqui,J., Sam,L.,
            Anstett,M., Mehra,R., Prensner,J.R., Palanisamy,N., Ryslik,G.A.,
            Vandin,F., Raphael,B.J., Kunju,L.P., Rhodes,D.R., Pienta,K.J.,
            Chinnaiyan,A.M. and Tomlins,S.A.
  TITLE     The mutational landscape of lethal castration-resistant prostate
            cancer
  JOURNAL   Nature 487 (7406), 239-243 (2012)
   PUBMED   22722839
REFERENCE   6  (bases 1 to 6568)
  AUTHORS   Dey,P., Ponnusamy,M.P., Deb,S. and Batra,S.K.
  TITLE     Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates
            histone methylation and chromatin remodeling in pancreatic cancer
  JOURNAL   PLoS One 6 (10), e26926 (2011)
   PUBMED   22046413
REFERENCE   7  (bases 1 to 6568)
  AUTHORS   Bartke,T., Vermeulen,M., Xhemalce,B., Robson,S.C., Mann,M. and
            Kouzarides,T.
  TITLE     Nucleosome-interacting proteins regulated by DNA and histone
            methylation
  JOURNAL   Cell 143 (3), 470-484 (2010)
   PUBMED   21029866
REFERENCE   8  (bases 1 to 6568)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   9  (bases 1 to 6568)
  AUTHORS   Chen,Y.X., Yan,J., Keeshan,K., Tubbs,A.T., Wang,H., Silva,A.,
            Brown,E.J., Hess,J.L., Pear,W.S. and Hua,X.
  TITLE     The tumor suppressor menin regulates hematopoiesis and myeloid
            transformation by influencing Hox gene expression
  JOURNAL   Proc Natl Acad Sci U S A 103 (4), 1018-1023 (2006)
   PUBMED   16415155
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474033.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001056703.1, XM_238731.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..6568
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..6568
                     /gene="Chd1"
                     /note="chromodomain helicase DNA binding protein 1"
                     /db_xref="GeneID:308215"
                     /db_xref="RGD:1306794"
     exon            1..208
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..5291
                     /gene="Chd1"
                     /EC_number="3.6.4.12"
                     /codon_start=1
                     /product="chromodomain-helicase-DNA-binding protein 1"
                     /protein_id="NP_001100935.1"
                     /db_xref="GeneID:308215"
                     /db_xref="RGD:1306794"
                     /translation="MNGHSDEESVRNGSGESSQSEDDSGSASGSGSGSSSGSSSDGSS
                     SQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAML
                     RKQTQQPQQQRPASSNSGSEEDSSSSEDSDASSSDVKRKKHNDEDWQMSGSGSPSQSG
                     SDSESEDERDKSSCDGTESDYEPKNKVKSRKPQNRSKSKSGKKILGQKKRQIDSSEDE
                     DDEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQTEDEEFETIERFM
                     DCRVGRKGATGATTTIYAIEADGDPNAGFEKSKEPGDVQYLIKWKGWSHIHNTWETEE
                     TLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERI
                     IAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFK
                     DCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGL
                     GKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSR
                     NMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLL
                     YKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYA
                     SLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSK
                     GSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRL
                     RERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRRQALDHFNAEGSEDF
                     CFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKG
                     SVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAE
                     ELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDI
                     ELEPERNSKNWEDIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRS
                     RSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERL
                     DAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTERAGGRLGKVKGPTFRISG
                     VQVNAKLVIAHEDELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIG
                     IYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEA
                     QRLSGAGGSKRRKTRAKKNKAMKSIKVKEEIKSDSSPLPSERSEEEDDNVNDSKPESK
                     DRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEK
                     GLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLH
                     KLYKHAIKKRQESQQNSDQNSNVPTTHVIRNPDMERLKENTNHDDSSRDGYSSDRHLS
                     QCHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHREWDHYRQDSRYYSDREKHRKLDD
                     HRSREHRPSVEGSLKDRCHSDHRSHSDHRMHSDHRSSTEHTHHKSSRDYRYLSDWQLD
                     HRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSSRKT"
     exon            209..410
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            411..524
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            525..589
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..739
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            740..1008
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1234
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1335
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1514
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1642
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1859
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1949
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2140
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2329
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2330..2492
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2645
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2717
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2718..2867
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2868..3016
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3113
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3114..3209
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3210..3386
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3387..3547
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3548..3589
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3590..3720
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3721..3859
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3860..4010
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4011..4133
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4134..4262
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4263..4403
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4404..4582
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4583..4679
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4680..4734
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4735..4945
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
     exon            4946..6568
                     /gene="Chd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccccaggtg acatagagag ggggccctgg aaacccgtgg atgttgaaga aaattcatct
       61 ttgaactttt gatattcgag gaaatcggca ttcatactcg tcttttatta ttctgaggag
      121 atttgtgttt tatttaaaac ttgttgatct ttacaatgaa tggacacagt gatgaagaaa
      181 gtgttagaaa tggcagcgga gaatcaagtc agtcagaaga tgattctggg tcagcatcag
      241 gctctggatc tggctcaagc tctggcagca gcagtgatgg gagcagcagc cagtctggga
      301 gcagcgactc tgattctggt tctgactccg gaagtcaatc agagtctgag tcagacacat
      361 cccgagagaa caaagttcaa gcaaaaccac caaaagttga tggagctgag ttttggaaat
      421 ctaaccccag tattctggct gttcagagat ctgcaatgct taggaagcag acacagcagc
      481 ctcagcagca gcgcccagct tcatctaata gtggatccga agaggattcc tctagcagtg
      541 aagactcaga cgcctcgtcc agcgatgtca agaggaaaaa gcataacgat gaagattggc
      601 aaatgtctgg gtctggatct ccatctcagt ctggttcaga ctcagaatct gaagacgaga
      661 gagataaaag tagctgtgat gggacagagt ctgattatga gccaaaaaac aaagtcaaaa
      721 gcagaaaacc tcagaataga tctaagtcaa aaagtgggaa aaaaattctt ggacagaaaa
      781 agaggcagat tgattcgtct gaggatgaag atgatgagga ctacgataat gataaacgaa
      841 gctctcgacg ccaggccacc gtcaatgtga gctacaagga ggatgaagag atgaaaactg
      901 actctgatga cctgctggag gtctgcggag aggacgtccc tcagacggag gatgaggagt
      961 ttgagaccat agaaaggttt atggattgca gagttgggcg gaaaggagct actggtgcta
     1021 ctacaaccat ttatgctatt gaagcagatg gtgacccaaa tgcaggattc gaaaaaagca
     1081 aagagccggg agacgtccag tatttaatta agtggaaagg gtggtcgcac atccataaca
     1141 cgtgggagac ggaagaaacc ctcaagcagc agaacgttag agggatgaaa aagttggata
     1201 attataagaa aaaagatcag gagacaaaac gatggctgaa aaatgcttct ccggaagatg
     1261 tggaatatta caactgccag caagagctta ccgatgacct ccacaaacag taccagatag
     1321 tggagcgcat aattgctcat tccaatcaga agtcagcagc tggtcttcct gattactatt
     1381 gcaaatggca ggggcttccc tactctgagt gcagctggga ggacggagcg ctcatttcca
     1441 aaaagttcca gacgtgtatc gatgagtatt ttagcaggaa tcagtcaaaa actacacctt
     1501 ttaaagattg caaagtactg aaacaaagac caagatttgt agctctgaag aaacaaccat
     1561 cctatattgg aggacatgag ggtttagaat tgagagacta tcagctgaat ggtttaaact
     1621 ggcttgctca ctcttggtgc aaaggaaata gttgcatact tgctgatgaa atgggccttg
     1681 gaaaaacgat acagaccatc tcatttttga actatttgtt tcatgaacat cagttatacg
     1741 gaccttttct actagttgtc ccgctctcca ctctgacttc ctggcaaagg gaaattcaga
     1801 cgtgggcgtc tcagatgaat gctgtggttt atttaggtga cattaacagc agaaacatga
     1861 taagaacgca cgaatggatg catccccaga ccaaacggtt aaagtttaac atacttttaa
     1921 caacgtatga aattttattg aaggataagg cattccttgg tggtctgaat tgggcattta
     1981 taggtgttga tgaagcacat cgattaaaaa atgatgattc ccttctatat aaaactttaa
     2041 ttgatttcaa atctaatcac cgcctcttaa tcactggaac tcctctgcag aactccctga
     2101 aagagctctg gtcattgctg catttcatta tgccagaaaa gttttcttca tgggaagatt
     2161 ttgaggaaga acatggtaaa ggcagagaat atggttatgc aagcctccac aaggagcttg
     2221 agccatttct gttacgcaga gttaagaaag atgtggaaaa atctcttcct gccaaggtgg
     2281 agcagatttt aagaatggaa atgagtgctt tacagaaaca atattacaag tggattttaa
     2341 ctaggaatta caaagccctc agcaaaggtt ccaagggcag tacctcaggc tttttgaaca
     2401 ttatgatgga gctaaagaaa tgttgtaacc attgctacct cattaaacca ccagataata
     2461 acgaattcta taataaacag gaggccttac aacacttaat ccgtagtagt ggaaaattaa
     2521 ttcttctaga caagctgttg attcgtctaa gagaaagagg caatcgagtc ctcatttttt
     2581 ctcagatggt gcggatgtta gatatacttg cagaatattt gaagtatcgc caattcccct
     2641 ttcaaagatt agatggatca ataaaagggg agctgaggag acaagctcta gaccacttta
     2701 atgcggaggg gtcagaggat ttctgctttt tgctctctac ccgagctggg ggtttaggca
     2761 ttaacttagc ctctgctgac actgttgtta tattcgattc ggattggaat ccacaaaatg
     2821 atcttcaggc tcaagctaga gctcatcgaa ttgggcagaa gaaacaggtg aatatatatc
     2881 gcttggttac aaagggatcc gttgaagaag atattcttga aagggccaaa aagaaaatgg
     2941 tcttggatca tcttgtgatt caacgaatgg ataccactgg gaagacagtg ttgcacacag
     3001 gctccgctcc atcaagttct acccccttca ataaagagga attatcagcc attttaaagt
     3061 ttggtgctga ggagcttttt aaggagcctg aaggagaaga gcaggagccc caggagatgg
     3121 atatagatga aatcttgaag agagctgaga ctcacgaaaa tgagccaggc ccgctgactg
     3181 tcggggatga gctgctctcc cagtttaagg ttgccaattt ttcaaatatg gatgaagatg
     3241 acattgaatt ggaacctgaa agaaattcaa agaactggga ggacatcatt ccagaagagc
     3301 aaagacgacg gttagaagag gaggagagac aaaaggagct ggaagaaatt tatatgctcc
     3361 cgagaatgag aaactgtgca aagcagataa gtttcaatgg aagtgaaggg cggcggagta
     3421 gaagcagaag atactcggga tctgatagtg attcaatctc ggaaaggaag cggccgaaga
     3481 aacgtgggcg accacgcacc atccctcggg agaacattaa aggctttagt gatgcggaga
     3541 ttaggcggtt tatcaagagc tataagaaat ttggtggccc tctggagagg ttagatgcaa
     3601 ttgctcgaga tgctgaattg gttgataaat cggaaacaga cctcagaaga ctaggagaac
     3661 tggtgcataa tggttgtgtt aaagctttaa aagatagttc ttcgggaaca gagcgagcag
     3721 gtggcagact tggaaaggtg aaggggccaa cgttccgaat atccggagta caggtgaatg
     3781 cgaagctggt cattgctcac gaggacgagc tgataccttt gcataagtcc attccctcag
     3841 acccggagga gaggaagcag tatacaatcc catgccatac aaaggctgct cacttcgata
     3901 tagactgggg caaagaggat gactcgaatt tattaattgg tatctatgaa tatggctatg
     3961 gaagctggga aatgattaaa atggatccag acctcagctt aacacacaag attcttccag
     4021 atgatcctga taaaaaacca caagcaaaac agttacagac tcgagcagac tacctcatca
     4081 aactacttag cagagatctt gcaaaaaaag aggctcagag gctttctggt gcgggaggct
     4141 caaagaggag aaaaacaaga gctaaaaaga ataaagcaat gaagtccatc aaagtcaaag
     4201 aggaaataaa gagtgactca tcgcccctgc cttcagagag gtctgaggag gaggacgata
     4261 acgtgaatga ctccaagcct gaaagtaaag accgctccaa aaagtctgtg gtgtctgatg
     4321 ctcccgtcca catcactgca agtggagagc cagtccccat agctgaagag tctgaagagc
     4381 tggatcagaa gacattcagt atttgtaaag aaagaatgag accggtgaag gcagctttga
     4441 aacaacttga caggcctgag aagggccttt cggaaagaga gcagctggaa cacactagac
     4501 agtgtttaat caagatcggc gaccatatca ctgaatgttt gaaggagtat tccaatcctg
     4561 agcaaattaa gcagtggaga aaaaacctgt ggatttttgt ttctaagttt actgaatttg
     4621 atgcaaggaa attacataaa ttatataagc atgctattaa aaaacgacaa gaatctcagc
     4681 aaaacagtga ccagaatagc aatgttccta ccactcatgt gattaggaat ccagacatgg
     4741 aaaggttaaa agagaataca aatcacgatg acagcagcag ggacggctac tcttcggaca
     4801 gacacttatc tcagtgccat gatcatcaca aggaccgcca tcagggagac tcttataaaa
     4861 agagtgactc tcggaagaga ccctactcct catttagcaa cggcaaagac catcgcgagt
     4921 gggatcacta caggcaagac agtaggtact atagtgacag agagaaacac agaaaactgg
     4981 atgaccacag gagtcgagag cacaggccaa gtgtggaagg cagcttaaag gacaggtgtc
     5041 attctgacca ccgatctcac tcggaccatc ggatgcattc agaccatcgc tccagcactg
     5101 agcacacaca ccataagtct tccagggatt ataggtacct ctcagattgg cagctggacc
     5161 accgagctgc cagcagtggc cctaggtctc ctttagatca gaggtctcca tatggctcca
     5221 ggtccccatt tgaacattca gctgaacaca gaagtacacc tgaacacacc tggagtagtc
     5281 ggaagacata acagatactg atggttttgt ctttctggac ttcattttag ccatagatca
     5341 taaaccaaca cagtaattgc cttacatgac ttgaaagata caaacagctc ttctatctat
     5401 cggtagcagt attgttactt ctttccagga cgcaaggtct attatcccaa cagaagagaa
     5461 gatattttta tatttaagga ttatgctgca ctgtactgca atactgtagt accttttttt
     5521 ctttttttaa agaaatggaa aatgtttact ataccaggga cctcagcact gccctcccgt
     5581 gtaggctgta taaaactgtt tatacgtcag tgattttaga ctgactccat ttaaattatg
     5641 tttgtatatg aactttactc tgacctgtga tcatgtttca ggaaggaatg aaagagaggt
     5701 cttttcttaa taaagaaaaa tcgctcaagg actttgttca ctttccaaag ctacttgttt
     5761 acattgtaca ctgcgaccac cttgccgctt cccgtcacaa gcttgaatat ttaaatcctg
     5821 tactgaagtc tgtaagatag ccgggaactt cctgtttgtg attattatta tgccttttta
     5881 cagaagaaga tggctgtaaa ttattgtaaa tgtataaatg agctttcctt ccttaccctt
     5941 ctcaggcttc ttctgactgt tcctttccct accaactcag gccttcttat taaaaaaaaa
     6001 aaaatcagtg taataacact ctttaatgat ttgtctcgat ggaatcattg tttagaatgt
     6061 aaaaatgggg aaaggggcca cttattcatt tcgtcctctt tttatattga atatttttgt
     6121 tagatacatg ttttacccct cctttttaaa gtcaattttg tgtttgtagt ttttacagaa
     6181 gaagaagtgg tgagggttac atgtgagata gaaacttgat gctctgggaa agtttgcaga
     6241 tgcatttggt ttaaaagggt aggtgtgtga acactttcaa aatccagact ggccaaacgt
     6301 tcttgtgagt ccatttgttt tccctctcac gtgggcaata atgtcaaatg tgctatgcag
     6361 ccaggctaac attttagacg gacttgattg actttttaat ataaactgtt acagtgcaca
     6421 ctgattgtac ataaaacctt atatatgaca aattaaattc taagaaaaag gatatgtggg
     6481 ctcctggagt ttctgctgca tccttgtttc ctcaagcatt taatcttttg ttttaagtaa
     6541 ctgctgccag aaagaaaggt gttttggt
//
