LOCUS       NM_001106608            1078 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain
            containing 6 (Chchd6), mRNA.
ACCESSION   NM_001106608 XM_001072660 XM_001072693 XM_216212
VERSION     NM_001106608.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Guarani,V., McNeill,E.M., Paulo,J.A., Huttlin,E.L., Frohlich,F.,
            Gygi,S.P., Van Vactor,D. and Harper,J.W.
  TITLE     QIL1 is a novel mitochondrial protein required for MICOS complex
            stability and cristae morphology
  JOURNAL   Elife 4, e06265 (2015)
   PUBMED   25997101
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1078)
  AUTHORS   Ott,C., Dorsch,E., Fraunholz,M., Straub,S. and Kozjak-Pavlovic,V.
  TITLE     Detailed analysis of the human mitochondrial contact site complex
            indicate a hierarchy of subunits
  JOURNAL   PLoS One 10 (3), e0120213 (2015)
   PUBMED   25781180
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1078)
  AUTHORS   Zerbes,R.M., van der Klei,I.J., Veenhuis,M., Pfanner,N., van der
            Laan,M. and Bohnert,M.
  TITLE     Mitofilin complexes: conserved organizers of mitochondrial membrane
            architecture
  JOURNAL   Biol Chem 393 (11), 1247-1261 (2012)
   PUBMED   23109542
  REMARK    Review article
REFERENCE   4  (bases 1 to 1078)
  AUTHORS   An,J., Shi,J., He,Q., Lui,K., Liu,Y., Huang,Y. and Sheikh,M.S.
  TITLE     CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of
            mitofilin and mitochondrial cristae morphology
  JOURNAL   J Biol Chem 287 (10), 7411-7426 (2012)
   PUBMED   22228767
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001072660.1, XM_001072693.1, XM_216212.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ219980.1, SRR8487227.345644.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1078
                     /gene="Chchd6"
                     /note="coiled-coil-helix-coiled-coil-helix domain
                     containing 6"
                     /db_xref="GeneID:297436"
                     /db_xref="RGD:1304561"
     exon            1..180
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..879
                     /gene="Chchd6"
                     /note="coiled-coil-helix-coiled-coil-helix
                     domain-containing protein 6, mitochondrial"
                     /codon_start=1
                     /product="MICOS complex subunit Mic25"
                     /protein_id="NP_001100078.1"
                     /db_xref="GeneID:297436"
                     /db_xref="RGD:1304561"
                     /translation="MGSSESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQP
                     SAGEQLAPGPGPECSVPVPTVPQPTIPVLTVPSPSVCGPAEGTYKAPQGDFKVSRAEN
                     SDGQQSSAVKEDLKKFQQEQLAVQDELVKVARKEKEATEKHLKASLPKKKATHEQQQS
                     DRLTRELKNREAELSRRDTFYKEQQERIQEKNAELYKLSSQQFHEAASKAESTIKPRR
                     VEPVCSGLQAQILRCYRDHLHEVLLCSDLAKAYQHCVSTARKG"
     exon            181..373
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            374..443
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            444..582
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            583..666
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            667..737
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            738..873
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1078
                     /gene="Chchd6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtcccgagt gacgagcgca ggccgctgag cagcgtcatc ccggttgctg tggagccggc
       61 tcgcgtggcc gtacgccttg cccgcctcct gtcatgggca gctcagagag cgccgaggcc
      121 cgaagggtgt ccttcgagat ggatgaggag gagcgggtcc gggtgctgca gggcatccgg
      181 ctgtccgaaa gtgttgtgaa ccgcatgaag gattgcagcc agccttcagc aggggaacag
      241 ctggctcctg gtcctggtcc tgagtgctcc gttcctgtgc ccactgtccc tcaaccaacc
      301 attccagtgc ttactgttcc ttcaccctct gtatgtgggc ccgcagaagg cacctataaa
      361 gcccctcagg gagactttaa agtgtccagg gcagagaata gtgatggcca gcagtcctca
      421 gcagtgaagg aggatctcaa gaagttccaa caggagcagc tggcagtcca ggatgagctg
      481 gtcaaggtgg caagaaagga gaaagaggca actgagaagc acttgaaggc atccctgccc
      541 aagaagaagg ccacccacga gcagcagcag tcagatcgcc taaccaggga actgaagaac
      601 agagaggccg agctcagccg ccgtgacact ttctacaagg agcagcagga acgcatccaa
      661 gagaagaatg ctgagctgta taaactgtct tctcaacaat tccacgaggc ggcttcaaaa
      721 gcagagagca caataaagcc ccgcagagtg gagcctgtat gctctggcct acaggcccag
      781 atcctccgct gctaccgtga ccatctgcat gaggtacttc tatgctccga cctggccaag
      841 gcataccagc actgtgtgag caccgcccgc aagggctgag gagcagcatc cttcctggag
      901 ccttgaagaa gggaccgatc atgagaccac agaccatggt ccccatgccc tgcagtctct
      961 gactgagcac ccatatgcct ctgagcatgg ggctgccatg ctcaagaaac agtatgtgct
     1021 actgatggaa aacaaataaa gcagatgtct ttgtttgcag tcattcactc attggcac
//
