LOCUS       NM_001106588            1504 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain
            containing 3 (Chchd3), mRNA.
ACCESSION   NM_001106588 XM_001066573 XM_238346
VERSION     NM_001106588.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Guarani V, McNeill EM, Paulo JA, Huttlin EL, Frohlich F, Gygi SP,
            Van Vactor D and Harper JW.
  TITLE     QIL1 is a novel mitochondrial protein required for MICOS complex
            stability and cristae morphology
  JOURNAL   Elife 4, e06265 (2015)
   PUBMED   25997101
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  AUTHORS   Ott C, Dorsch E, Fraunholz M, Straub S and Kozjak-Pavlovic V.
  TITLE     Detailed analysis of the human mitochondrial contact site complex
            indicate a hierarchy of subunits
  JOURNAL   PLoS One 10 (3), e0120213 (2015)
   PUBMED   25781180
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1504)
  AUTHORS   Zerbes RM, van der Klei IJ, Veenhuis M, Pfanner N, van der Laan M
            and Bohnert M.
  TITLE     Mitofilin complexes: conserved organizers of mitochondrial membrane
            architecture
  JOURNAL   Biol Chem 393 (11), 1247-1261 (2012)
   PUBMED   23109542
  REMARK    Review article
REFERENCE   4  (bases 1 to 1504)
  AUTHORS   Liu H, Li Y, Li Y, Liu B, Wu H, Wang J, Wang Y, Wang M, Tang SC,
            Zhou Q and Chen J.
  TITLE     Cloning and functional analysis of FLJ20420: a novel transcription
            factor for the BAG-1 promoter
  JOURNAL   PLoS One 7 (5), e34832 (2012)
   PUBMED   22567091
REFERENCE   5  (bases 1 to 1504)
  AUTHORS   Darshi M, Mendiola VL, Mackey MR, Murphy AN, Koller A, Perkins GA,
            Ellisman MH and Taylor SS.
  TITLE     ChChd3, an inner mitochondrial membrane protein, is essential for
            maintaining crista integrity and mitochondrial function
  JOURNAL   J Biol Chem 286 (4), 2918-2932 (2011)
   PUBMED   21081504
REFERENCE   6  (bases 1 to 1504)
  AUTHORS   Zhao X, Leon IR, Bak S, Mogensen M, Wrzesinski K, Hojlund K and
            Jensen ON.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   7  (bases 1 to 1504)
  AUTHORS   Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A,
            Nicolaescu E, Lesage B and Bollen M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   8  (bases 1 to 1504)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   9  (bases 1 to 1504)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   10 (bases 1 to 1504)
  AUTHORS   Da Cruz S, Xenarios I, Langridge J, Vilbois F, Parone PA and
            Martinou JC.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473959.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066573.1, XM_238346.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ216356.1, FQ215338.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..1504
                     /gene="Chchd3"
                     /note="coiled-coil-helix-coiled-coil-helix domain
                     containing 3"
                     /db_xref="GeneID:296966"
                     /db_xref="RGD:1310325"
     exon            1..240
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..843
                     /gene="Chchd3"
                     /note="coiled-coil-helix-coiled-coil-helix
                     domain-containing protein 3, mitochondrial"
                     /codon_start=1
                     /product="MICOS complex subunit MIC19"
                     /protein_id="NP_001100058.1"
                     /db_xref="GeneID:296966"
                     /db_xref="RGD:1310325"
                     /translation="MGGTASTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGS
                     KSQRYSSVYGASVSDEELKRRVAEELALEQAKMESENQRRLKHARDLEREKAVANEQL
                     TRAILQERISSEENRTKVKHLARQLEEKDRMIRKQDAFYKEQLSRLEERSSEFYKVTT
                     EEYQKAAEEVESKFRRYEYHPVCADLQTKILQCYRQNTQQTLSCSALANQYMHCVNHA
                     KQNMLEKGG"
     exon            241..328
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            329..410
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            411..528
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            529..612
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            613..683
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            684..819
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
     exon            820..1504
                     /gene="Chchd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgccttc tccttgctct ttggggtcgt ggccttgctc ctacccggca agggaagcgt
       61 cctgggcttt cacgcgcaag tgtgcgcgtg ggtcctgacg tgctcgtagg tccacgctca
      121 ggtccacgct cagactctgc ggggacagaa gctggagcca tgggcgggac cgctagcacc
      181 cgccgggtca ccttcgaggc ggacgagaac gagaacatca cggtggtgaa gggcatccgg
      241 ctgtcagaga atgtgatcga ccggatgaag gagtcctctc catctggctc taagtctcag
      301 cgatattcca gtgtttatgg tgcttcagtt tctgatgaag aattgaaaag aagagtagcc
      361 gaggagctgg cattggaaca agccaaaatg gagtcggaaa accagagacg ccttaagcac
      421 gccagggacc tagaaagaga gaaagctgtg gccaatgagc agctgaccag agctatcctt
      481 caggaaagaa tatccagtga ggagaaccgc acaaaggtga agcatctggc tcggcagctg
      541 gaagagaaag atcgaatgat acggaagcag gatgcgttct acaaagagca gctgtccaga
      601 ctggaggaga ggagctcaga attctacaaa gttactaccg aggaatatca gaaagctgct
      661 gaagaggtgg agtccaagtt caggcggtat gaatatcatc cagtctgtgc agatctgcag
      721 accaaaatcc ttcagtgtta ccgtcagaac acccagcaga ccctcagctg ctctgctctg
      781 gccaaccaat acatgcactg tgtcaaccat gccaaacaga acatgctgga gaagggaggc
      841 taaagttacc ctgagaacat gcgaagctcc ttcaacgtta attccagagg tggaacattt
      901 tttttttcgt agtctgaaaa tgacccaatt aaagagaaga ccactaaaaa cagacaggca
      961 ctggaatgtg gactcaactg aatcataacg tgttttgatc aacagtttaa aaagccacgg
     1021 tttagatcag tcatcagaga acactgttaa gtgttaatga aactacaaaa tgaataaaag
     1081 agaaagaggt ccaccccacc tttttgttct ctgtttccaa cttctactga cataaagtgt
     1141 tctcttcact ccaggctcca gcatttagtg acttcaccct gagaaagctg ggaggaggga
     1201 cattaaatta tttcaaaata gagacagcaa gaaagcactg ggctagggca gcagtatcgg
     1261 gtggcctggg ctgtgaggct gggtgtgagc ctcttgctat gtaggagcta attccttgta
     1321 acttatgatg atcttccaag acagacagac aggagagaaa atgtacctct ttactggaat
     1381 aatgtttatg attgcaggta aaataaggta tttttgtcaa tataaaggca accttggctt
     1441 attcaaccaa gtagtgaata ctgacaactt cactcactat caataataaa tctattttct
     1501 gaca
//
