LOCUS       NM_001024741            1958 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus chromatin assembly factor 1 subunit B (Chaf1b),
            mRNA.
ACCESSION   NM_001024741 XM_213664
VERSION     NM_001024741.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1958)
  AUTHORS   Reddy D, Bhattacharya S, Shah S, Rashid M and Gupta S.
  TITLE     DNA methylation mediated downregulation of histone H3 variant H3.3
            affects cell proliferation contributing to the development of HCC
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1868 (1), 166284 (2022)
   PUBMED   34626773
  REMARK    GeneRIF: DNA methylation mediated downregulation of histone H3
            variant H3.3 affects cell proliferation contributing to the
            development of HCC.
REFERENCE   2  (bases 1 to 1958)
  AUTHORS   Doe K, Nozawa K, Hiruma K, Yamada Y, Matsuki Y, Nakano S, Ogasawara
            M, Nakano H, Ikeda T, Ikegami T, Fujishiro M, Kawasaki M, Ikeda K,
            Amano H, Morimoto S, Ogawa H, Takamori K, Sekigawa I and Takasaki
            Y.
  TITLE     Antibody against chromatin assembly factor-1 is a novel
            autoantibody specifically recognized in systemic lupus
            erythematosus
  JOURNAL   Lupus 23 (10), 1031-1041 (2014)
   PUBMED   24836587
REFERENCE   3  (bases 1 to 1958)
  AUTHORS   de Tayrac M, Saikali S, Aubry M, Bellaud P, Boniface R, Quillien V
            and Mosser J.
  TITLE     Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four
            new markers in high-grade gliomas
  JOURNAL   PLoS One 8 (9), e73332 (2013)
   PUBMED   24039914
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1958)
  AUTHORS   Burgess RJ and Zhang Z.
  TITLE     Histone chaperones in nucleosome assembly and human disease
  JOURNAL   Nat Struct Mol Biol 20 (1), 14-22 (2013)
   PUBMED   23288364
  REMARK    Review article
REFERENCE   5  (bases 1 to 1958)
  AUTHORS   Mascolo M, Ilardi G, Romano MF, Celetti A, Siano M, Romano S, Luise
            C, Merolla F, Rocco A, Vecchione ML, De Rosa G and Staibano S.
  TITLE     Overexpression of chromatin assembly factor-1 p60, poly(ADP-ribose)
            polymerase 1 and nestin predicts metastasizing behaviour of oral
            cancer
  JOURNAL   Histopathology 61 (6), 1089-1105 (2012)
   PUBMED   22882088
REFERENCE   6  (bases 1 to 1958)
  AUTHORS   Mascolo M, Vecchione ML, Ilardi G, Scalvenzi M, Molea G, Di
            Benedetto M, Nugnes L, Siano M, De Rosa G and Staibano S.
  TITLE     Overexpression of Chromatin Assembly Factor-1/p60 helps to predict
            the prognosis of melanoma patients
  JOURNAL   BMC Cancer 10, 63 (2010)
   PUBMED   20178651
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1958)
  AUTHORS   Staibano S, Mascolo M, Mancini FP, Kisslinger A, Salvatore G, Di
            Benedetto M, Chieffi P, Altieri V, Prezioso D, Ilardi G, De Rosa G
            and Tramontano D.
  TITLE     Overexpression of chromatin assembly factor-1 (CAF-1) p60 is
            predictive of adverse behaviour of prostatic cancer
  JOURNAL   Histopathology 54 (5), 580-589 (2009)
   PUBMED   19309489
REFERENCE   8  (bases 1 to 1958)
  AUTHORS   Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem
            P, Lehrach H, Yaspo ML and Janitz M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 1958)
  AUTHORS   Tagami H, Ray-Gallet D, Almouzni G and Nakatani Y.
  TITLE     Histone H3.1 and H3.3 complexes mediate nucleosome assembly
            pathways dependent or independent of DNA synthesis
  JOURNAL   Cell 116 (1), 51-61 (2004)
   PUBMED   14718166
REFERENCE   10 (bases 1 to 1958)
  AUTHORS   Verreault A, Kaufman PD, Kobayashi R and Stillman B.
  TITLE     Nucleosome assembly by a complex of CAF-1 and acetylated histones
            H3/H4
  JOURNAL   Cell 87 (1), 95-104 (1996)
   PUBMED   8858152
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097460.1.
            
            On Jun 10, 2005 this sequence version replaced XM_213664.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097460.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132265
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1958
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1958
                     /gene="Chaf1b"
                     /note="chromatin assembly factor 1 subunit B"
                     /db_xref="GeneID:288242"
                     /db_xref="RGD:1307634"
     exon            1..52
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            53..241
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1834
                     /gene="Chaf1b"
                     /note="chromatin assembly factor 1, subunit B (p60)"
                     /codon_start=1
                     /product="chromatin assembly factor 1 subunit B"
                     /protein_id="NP_001019912.1"
                     /db_xref="GeneID:288242"
                     /db_xref="RGD:1307634"
                     /translation="MKVITCEIAWHNKEPVYSLDFQHAAACRIQRLASAGVDTAVRIW
                     KVEKGPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKEPE
                     QIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGNMMASASVDNTVIIWDVSK
                     GQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNVSKMLSGQGP
                     EGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESGENVTNTTYVFSREHLKR
                     PIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVSLPYRMVFAVASEDSV
                     LLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAVSSTDGYCSFVTFEKGELGVPLK
                     EKPVLGVRTPDTAKKTKNQNPQGSSPGSRSAEGTPSNRIQDPSSPCTTPSPTTQSPAP
                     PAIKDSPSAIPAGKSPLPRPSEEKTLQPAAQNMKAPQPRRVTLNTLQSWGKTAPRRIN
                     LTPLRADTAPNPLPSSGAAPSTEEVQPEVPGEPQDEPPELKRPKLEEQEGDTQSLSPD
                     ETSKSA"
     exon            242..374
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            375..492
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            493..596
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            597..693
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            694..778
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            779..872
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            873..942
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1034
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1197
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1629
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1721
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1933
                     /gene="Chaf1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgcgggaa gctgcgggca gtggcggctc tgagtggacc gagtcctagc agggtcgctg
       61 ttgaactctt tgctaacatt cccagcctcc ctttgcctgg cggagactct ggaggatgaa
      121 agtgatcacg tgtgaaatcg cctggcacaa caaggagcca gtgtacagcc ttgacttcca
      181 gcatgcggca gcctgtagga tccaaaggct ggcgtccgcg ggggtggaca ccgccgttag
      241 gatctggaag gtggagaagg ggccagatgg aaaagccatt gtggaattcc tctccaacct
      301 tgctcggcac accaaagctg tcaatgttgt acgcttttct ccaactgggg agattttagc
      361 atctggagga gacgatgccg tcatcctgct gtggaagatg aatgacagca aggagccgga
      421 gcagatcgcc tttcaggatg aagatgaggc tcagctgaac aaggagaact ggactgtggt
      481 aaaaaccctg aggggccact tagaagatgt gtatgatata tgctgggcaa ctgatgggaa
      541 tatgatggcc tctgcttctg tggataacac agttatcata tgggatgtca gtaaaggaca
      601 gaagatttcc attttcaacg agcataaaag ttacgtgcaa ggagtgacct gggatcctct
      661 gggtcaatat atcgcgaccc tgagttgtga cagggtgctg cgggtctata gcacccagaa
      721 gaaacgtgtg gctttcaacg tttcaaagat gctctctgga caagggcccg aaggagaggc
      781 gagaagtttc cggatgtttc acgatgacag catgaagtcg ttcttccgaa gactcagttt
      841 tactccagat ggatctttgc tcctcactcc agctggatgt atggagtctg gtgagaatgt
      901 gacaaacacc acttatgtgt tctccagaga acatctgaaa aggccgattg cccaccttcc
      961 atgccctggg aaagcgaccc ttgctgtccg atgctgtcct gtgtactttg aactgaggcc
     1021 agtggcagaa acagagaaag cgtcagagga gcccagcccc gagctggtga gtctgcccta
     1081 ccgtatggtg ttcgcagtgg cctcggagga ctctgtgctg ctgtatgaca cgcaacagtc
     1141 tttcccattt ggttatgtgt ctaacatcca ttaccatacc ctgagtgaca tttcctggtc
     1201 cagcgatggg gccttcctgg ctgtgtcctc cacggatggt tattgctcat tcgtgacctt
     1261 tgagaaaggt gaactaggcg tgcctttgaa ggagaagccg gttctgggcg taagaactcc
     1321 tgacacagca aagaaaacca agaaccagaa cccccaggga tcttcgccag gatccagatc
     1381 agccgaagga acccccagca acagaatcca ggaccccagc agcccctgta ccaccccctc
     1441 accaaccaca cagtctccag ccccgcccgc catcaaggac agtccctcag ccatccctgc
     1501 cggcaaaagc cccttgccac ggccttctga ggagaagacc ctgcagcctg ccgctcaaaa
     1561 catgaaagcc ccccaacccc gcagggtcac actgaacacg ctgcagtctt ggggcaagac
     1621 ggccccccgg agaataaatt taacaccgtt gagggcagac actgcaccaa atccactgcc
     1681 cagtagcggg gccgccccct ccacagaaga ggtccagcca gaggtgcctg gagagcccca
     1741 ggatgagcct cccgaactga agagacctaa gcttgaagaa caggaaggag acacccaaag
     1801 cctgagtcct gatgagactt ccaagtctgc ctgaggcctg ctcggctggg tatccatgtg
     1861 cagaggaggc caaagctcga aggctggtga tggtgatatt agagcggaat aaacactcgt
     1921 gaattggttc acaaaaaaaa aaaaaaaaaa aaaaaaaa
//
