LOCUS       NM_053899               1264 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus cell growth regulator with ring finger domain 1
            (Cgrrf1), mRNA.
ACCESSION   NM_053899
VERSION     NM_053899.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Kaneko,M., Iwase,I., Yamasaki,Y., Takai,T., Wu,Y., Kanemoto,S.,
            Matsuhisa,K., Asada,R., Okuma,Y., Watanabe,T., Imaizumi,K. and
            Nomura,Y.
  TITLE     Genome-wide identification and gene expression profiling of
            ubiquitin ligases for endoplasmic reticulum protein degradation
  JOURNAL   Sci Rep 6, 30955 (2016)
   PUBMED   27485036
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  AUTHORS   Madden,S.L., Galella,E.A., Riley,D., Bertelsen,A.H. and
            Beaudry,G.A.
  TITLE     Induction of cell growth regulatory genes by p53
  JOURNAL   Cancer Res 56 (23), 5384-5390 (1996)
   PUBMED   8968090
  REMARK    GeneRIF: CGR19 appears to be a primary response gene expressed to
            moderate levels in functional p53 cells.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053899.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U66471.1, FQ218613.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               JAXUCZ010000015.1  22568364-22568569
            207-346             JAXUCZ010000015.1  22576977-22577116
            347-524             JAXUCZ010000015.1  22582215-22582392
            525-672             JAXUCZ010000015.1  22582523-22582670
            673-780             JAXUCZ010000015.1  22588012-22588119
            781-1264            JAXUCZ010000015.1  22588327-22588810
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1264
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /note="cell growth regulator with ring finger domain 1"
                     /db_xref="GeneID:116679"
                     /db_xref="RGD:620803"
     exon            1..206
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..1101
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /note="cell growth regulatory gene 19 protein; cell growth
                     regulatory with ring finger domain"
                     /codon_start=1
                     /product="cell growth regulator with RING finger domain
                     protein 1"
                     /protein_id="NP_446351.2"
                     /db_xref="GeneID:116679"
                     /db_xref="RGD:620803"
                     /translation="MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVIL
                     RNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGVTLTTDCLEDSRLTCYWGC
                     SVQKLYEALQKHVYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSSTGV
                     EDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILA
                     QGQFYDLKQLFMSANNSATPSRDQSPADGSVEHSLLEKAGLAGAEVDPVEESSKDCVV
                     CQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEADKDILETS"
     exon            207..346
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
     exon            347..524
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
     exon            525..672
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
     exon            673..780
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
     exon            781..1264
                     /gene="Cgrrf1"
                     /gene_synonym="Cgr19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgggcgag tgaggaccta caaagtttgt ccgctccggg gcgccatacc agctcggttc
       61 ccggccggcc gggctggtcc gggcttagcc caggagaccc cgatggccgc agtgttcctg
      121 gttacgctct acgaatactc gccgctcttc tacatcgcgg tggtcttcac ctgcttcatc
      181 gtcaccaccg gcctggtatt aggatggttt ggctgggacg ttccagtaat tctgagaaac
      241 tcagaagaaa cccagttcag cacaagagct ttcaagaaac aaatgagaca agtgaagaat
      301 ccgttcggct tagagatcac taactcatcc gcagcttccc tagcaacagg tgtaaccttg
      361 acgacagact gcctggaaga cagtcgtctt acgtgctact gggggtgcag tgttcaaaag
      421 ctctatgaag ctcttcagaa gcacgtttac tgcttcagga taagcactcc gcaagccttg
      481 gaagaggcgc tgtacagtga ctatctccac cgagaacagt attttattaa aaagcacagc
      541 aaagaagaaa tatattgcca attaccaagc agtactgggg ttgaagactt tggtccagtg
      601 cccagatctc gctatccatt ggtagctctg ttgaccctcg ctgatgagga tgacagggaa
      661 atttatgaca ttatttccat ggtgtctgtc attcatattc ctgataagac ttacaaactt
      721 ccctgcagaa tattgtatca atatttaatc ctggctcaag gtcaatttta tgatcttaag
      781 caacttttca tgtctgcaaa taatagtgct actccctcca gagaccagtc tcccgcagac
      841 gggagtgtgg agcacagctt gttggagaag gcggggctgg ctggggctga agtggacccg
      901 gtggaggaga gcagcaaaga ctgtgtggtg tgccagaacg ggggtgtgaa ctgggtgctc
      961 ctgccttgcc ggcacgcctg cctgtgcgac agctgtgtgt gctacttcaa gcagtgtccc
     1021 atgtgccgcc agtttgtgca ggaatccttt gcactgtgtg gtcagaaaga ggcagacaag
     1081 gacatactag aaacttcctg aagaatcaca gccggagagt gtactttcta cacaagggca
     1141 gaacctcgtg tccttagagt caatcctaac agagtctgca gtcttacctg tcggagagag
     1201 ctctgtgtgc acttcatact tgtacagtac atggatgacg ggaataaagt cttcctgctc
     1261 agtg
//
