LOCUS       NM_012525               2290 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus carcinoembryonic antigen gene family 4 (Cgm4),
            mRNA.
ACCESSION   NM_012525 XM_214842
VERSION     NM_012525.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2290)
  AUTHORS   Rebstock,S., Lucas,K., Thompson,J.A. and Zimmermann,W.
  TITLE     cDNA and gene analyses imply a novel structure for a rat
            carcinoembryonic antigen-related protein
  JOURNAL   J Biol Chem 265 (14), 7872-7879 (1990)
   PUBMED   2335509
REFERENCE   2  (bases 1 to 2290)
  AUTHORS   Kodelja,V., Lucas,K., Barnert,S., von Kleist,S., Thompson,J.A. and
            Zimmermann,W.
  TITLE     Identification of a carcinoembryonic antigen gene family in the
            rat. Analysis of the N-terminal domains reveals
            immunoglobulin-like, hypervariable regions
  JOURNAL   J Biol Chem 264 (12), 6906-6912 (1989)
   PUBMED   2708349
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB706316.1, CV118170.1, CB804911.1, CB766157.1, CB786391.1,
            BI285964.1, BI283810.1 and AA818022.1.
            
            On May 21, 2005 this sequence version replaced XM_214842.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097366.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN09345330 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                CB706316.1         1-37
            38-774              CV118170.1         2-738
            775-946             CB804911.1         238-409
            947-1238            CB766157.1         127-418
            1239-1501           CB786391.1         190-452
            1502-1736           BI285964.1         18-252              c
            1737-2280           BI283810.1         12-555              c
            2281-2290           AA818022.1         1-10                c
FEATURES             Location/Qualifiers
     source          1..2290
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2290
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /note="carcinoembryonic antigen gene family 4"
                     /db_xref="GeneID:24257"
                     /db_xref="RGD:1307652"
     exon            1..285
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1634
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /codon_start=1
                     /product="carcinoembryonic antigen gene family 4
                     precursor"
                     /protein_id="NP_036657.1"
                     /db_xref="GeneID:24257"
                     /db_xref="RGD:1307652"
                     /translation="MTVRRQMEASSVFPFKGCTPCQGFLLTASLLTCWLLTTAQVNIE
                     SVPFNVVEGENVLLLVHNLPENLIAFAWYRGLRKIGVYILNTEVSVTGPMYSGRETVY
                     SNGSLCIRNVTQKDTGFYTLRTVNTRGETVSTTSLYLYVYTSLFICGRPFNPAKLTIE
                     SVPPSVAEGGSVLLLVHNLQDELRGFFWYKGASMSSNHEIARYRTAKNSSVPGPAHSG
                     RETVYSNGSLLLQNVTRNDTGFYTLRTLKRHQKMELAHVQLQVDTSLSSCCDPLTSAQ
                     LTIDPVPRHAAEGESVLLRVLNLPEDFQVFCWYRGVSTFQVFKIAEYSRARNSITKGP
                     AESRTERVYTNGSLLLQDVTEKDTGLYTLQMIDSSFNIETAPVQITVHKPVTQPFLRV
                     TESTVTVQSAVVFTCFSDNTGISIRWLFKNHYLQPTERITLSPSKCQLHINPVRKEDA
                     GEYRCEVFNPVSSKTSLPVSLVVRNE"
     exon            286..630
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /inference="alignment:Splign:2.1.0"
     exon            631..990
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1350
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..2283
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2245..2250
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
     regulatory      2249..2254
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
     polyA_site      2278
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
                     /experiment="experimental evidence, no additional details
                     recorded"
     polyA_site      2283
                     /gene="Cgm4"
                     /gene_synonym="Cea; CEA4; CEA5; Cear; CGM4AA; Psg16"
ORIGIN      
        1 aaagagagaa aagttggagg gatgcagggc agcactgagg gtagaaagga ctgagcagtg
       61 ccttggaccc gaccccacta cccacagctc actggattct gggaagtgct cctgcctgag
      121 aggaaactca gttcagaagg aggaaggaca gcagaggcca gctgccttgt tggagttgaa
      181 ggtcttctcc tcagagcaag aacatgacag tgagaagaca gatggaggca tcctctgtgt
      241 ttcccttcaa ggggtgtacc ccctgccaag ggttcctcct cacagcctcc cttctaacct
      301 gttggctcct gactactgcc caggtcaaca ttgaatcggt gccattcaat gtggttgaag
      361 gggaaaacgt ccttcttctt gtccacaatc tgccagagaa tctcatagcc tttgcctggt
      421 atagagggct gaggaaaatt ggagtataca tactgaacac tgaagtaagt gtgacggggc
      481 caatgtacag cggtagagag acagtgtaca gcaatggttc cctgtgtatc cgcaatgtca
      541 cccagaagga cacaggattc tacactctac gaacagtcaa cacacgtgga gaaactgtat
      601 caacaacatc cttgtacctc tatgtgtaca cctctctttt catctgtggg cgtcctttta
      661 accctgccaa gctcactatt gaatcagtgc cgcccagtgt tgctgaaggg ggaagcgttc
      721 ttctcctcgt tcacaatctc caggacgagc ttcgagggtt tttctggtac aaaggggcgt
      781 ctatgtctag caaccatgag atagcccgat acagaacagc aaagaattca agtgtgccag
      841 gccctgccca cagtggtaga gagacggtgt acagcaatgg atccctcctg ctccagaatg
      901 tcacccggaa tgacactggg ttctacaccc tacgcactct gaaaagacat cagaaaatgg
      961 aattggcaca cgtgcaactt caggtggaca cctccctttc ctcatgctgt gaccctctca
     1021 cctctgccca actcacgata gatccagtgc cacggcatgc ggctgaaggg gaaagcgtcc
     1081 ttctccgtgt tcttaatctg ccagaagact ttcaagtttt ttgctggtac agaggggtat
     1141 ctaccttcca ggtctttaaa attgcagaat atagcagagc caggaattcc atcaccaagg
     1201 ggcctgcaga aagcagaaca gagagagtgt acaccaacgg atccctgctg ctccaggacg
     1261 tcactgagaa agacacgggc ttgtacactc tacaaatgat agacagtagt ttcaacattg
     1321 aaacagcacc tgtccaaatc accgtgcaca agcctgtgac acagcctttc ctgagagtca
     1381 cggagagcac agtgacagta cagagcgcag tggtcttcac ttgcttctcg gacaacactg
     1441 ggatctccat ccgttggctc ttcaagaatc attatctgca gcccacagag aggatcacac
     1501 tgtccccatc taagtgccaa ctccacataa atcctgtcag gaaggaggat gctggagagt
     1561 atcgatgtga ggtcttcaac ccagtcagct caaagaccag tctcccagtc agtctggttg
     1621 tgaggaatga gtgacccctc ctctcatgct acagcagaag ggaggcattc ctttgtcaat
     1681 ggggtacaaa atggatgcaa tttccacagt aaaaattgtc agtaactggt catgtacctc
     1741 cagcatggtg gctcctgcct gtagttctga cacaacaagg tacagaagaa caggccaaaa
     1801 ggaacaggtg cccaaaggaa aatagagaca tcgatacagt aaacagtatt gcaactgtgt
     1861 taagacatta ggttgtggat tgaatgtatc acgaaccccg agaatctatg gcaactagta
     1921 tcaggagtct ccaaactttg gatgttccat gtgccctgtt aacatggtcc agtgtttgca
     1981 cagcgacaaa tatgcactca tatgctccaa tagtttcacc caaacccaaa gctggacccc
     2041 agtcacccat gggaagtgcg aaagatggca gaaaggactg accatttttc tcagtgcaca
     2101 taactggcta ctagatagtt ttgatccaca gtttctttga tgcacagaat tgaaatcctt
     2161 tgtgtaaaag ccaactggaa tgtttgtatc ctaagggtgg caggcacaac gtgaccttgc
     2221 acacaattct tttctgtatg cataaataaa taaatataat atagatgata tataaaaata
     2281 taaaaaaaaa
//
