LOCUS       NM_001134792            2715 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus complement factor H-related 4 (Cfhr4), mRNA.
ACCESSION   NM_001134792 XM_573464
VERSION     NM_001134792.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2715)
  AUTHORS   Bastos-Amador,P., Royo,F., Gonzalez,E., Conde-Vancells,J.,
            Palomo-Diez,L., Borras,F.E. and Falcon-Perez,J.M.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
REFERENCE   2  (bases 1 to 2715)
  AUTHORS   Hellwage,J., Eberle,F., Babuke,T., Seeberger,H., Richter,H.,
            Kunert,A., Hartl,A., Zipfel,P.F., Jokiranta,T.S. and Jozsi,M.
  TITLE     Two factor H-related proteins from the mouse: expression analysis
            and functional characterization
  JOURNAL   Immunogenetics 58 (11), 883-893 (2006)
   PUBMED   17028856
REFERENCE   3  (bases 1 to 2715)
  AUTHORS   Ren,G., Doshi,M., Hack,B.K., Alexander,J.J. and Quigg,R.J.
  TITLE     Isolation and characterization of a novel rat factor H-related
            protein that is up-regulated in glomeruli under complement attack
  JOURNAL   J Biol Chem 277 (50), 48351-48358 (2002)
   PUBMED   12374811
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Sep 7, 2008 this sequence version replaced XM_573464.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF436847.2, SRR26643286.36490.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               JAXUCZ010000013.1  54042058-54042179   c
            123-299             JAXUCZ010000013.1  54024969-54025145   c
            300-482             JAXUCZ010000013.1  54012882-54013064   c
            483-659             JAXUCZ010000013.1  54011560-54011736   c
            660-833             JAXUCZ010000013.1  54007311-54007484   c
            834-1016            JAXUCZ010000013.1  54005885-54006067   c
            1017-1196           JAXUCZ010000013.1  54005620-54005799   c
            1197-1373           JAXUCZ010000013.1  53991916-53992092   c
            1374-1556           JAXUCZ010000013.1  53989592-53989774   c
            1557-1766           JAXUCZ010000013.1  53988426-53988635   c
            1767-1949           JAXUCZ010000013.1  53985429-53985611   c
            1950-2715           JAXUCZ010000013.1  53973301-53974066   c
FEATURES             Location/Qualifiers
     source          1..2715
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..2715
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /note="complement factor H-related 4"
                     /db_xref="GeneID:498241"
                     /db_xref="RGD:1564614"
     exon            1..122
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..2149
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /note="complement factor H-related protein; complement
                     factor H-related protein-like"
                     /codon_start=1
                     /product="complement factor H-related 4 precursor"
                     /protein_id="NP_001128264.1"
                     /db_xref="GeneID:498241"
                     /db_xref="RGD:1564614"
                     /translation="MRFYSIWLLANILLITSLSTAKGEEECVLHYVENGYSLFLERKF
                     VQDQSVKVNCYKGFNLPNGQDTITCTESGWTPQPICIPSETCSKSDIEIDNGFFSESD
                     LTYAVNRKTRYVCKQGYTTANGERSGSITCLQTGWSAQPSCIKSCDVPVFENAKSKND
                     STWFKLNDKLDYECHIGYENKYKHTKGSIMCTTDGWSDKPSCYEIECSIPILDPRLVV
                     YPRKIKYTVGDLLKFSCRPGHRVGPDSVQCYDFGWSPSFPTCKGQVRSCGQYPELLNG
                     EIKGTKKAEYSHGDVVEYDCKPRFLLKGPNKIQCVDGKWTTLPTCVEEKRTCGDIPAL
                     EHGSVKFSVPPYHHGDSVEFTCAETFTMIGQRSVSCISGRWAQLPRCVATVQLEKCKA
                     PRLAVIGANKLEKDGLNHNSSISYKCRGSQKYGYSICINGRWDPEPTCTRKEKAFCPP
                     PPQIPNAQVIDTTVKYLDGEKVSVLCQDGYLTQGPEEMVCKHGRWQSLPRCTAKITCS
                     QPPKIDHGSIKLPRLSDAGRDAIDSSSHEHGTTFSYVCDDGFRISKENGVTCHMGKWS
                     SPPRCVESTGKCGPPPTIENGDITSLSLPVYAPLSSVEYQCQSFYKMQGSKKITCKNG
                     EWEEPPKCLHACVLTEEIMRRQNIIPKRTKNKKIYIQSGDYVEFVCLTAYQKAQGSPE
                     FRTQCIDGHINYPTCSK"
     exon            123..299
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            300..482
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            483..659
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            660..833
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1016
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1196
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1373
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1556
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1766
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1949
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2715
                     /gene="Cfhr4"
                     /gene_synonym="RGD1564614"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcagtttcc cagaagctcc accacacctg gagtcttagt ctttagaaga tgaggttcta
       61 tagcatatgg ctcttagcaa atattctcct aatcacatca ctttctactg ctaaagggga
      121 agaggaatgt gttttgcatt atgtggaaaa tggttattct ttattcttgg aaagaaaatt
      181 tgtacaagat cagtctgtca aagtcaactg ttataaaggc ttcaaccttc caaatggtca
      241 ggatacaatt acatgtacag agagtggctg gacacctcaa cccatatgca tcccttctga
      301 gacatgctca aagtcagata tagaaattga taatggattt ttttctgaat ctgatttaac
      361 atatgctgta aatagaaaaa cacgatatgt gtgtaaacag ggatatacaa cagcaaatgg
      421 agaaagatcg ggatcaatca cttgcctaca aactggatgg tctgctcaac cttcttgcat
      481 taagtcttgt gatgtgcctg tgtttgagaa tgctaaatct aaaaatgata gcacatggtt
      541 taaactcaat gacaaattag attatgaatg tcacattgga tatgaaaata aatataagca
      601 taccaaaggc tccataatgt gtactactga tggatggtct gataaaccct catgttatga
      661 aattgaatgc agcattccca tattagaccc acgcttagtt gtttatccca ggaaaataaa
      721 atatacagtt ggagatttgt tgaaattctc ttgccgacca ggacacagag ttggaccaga
      781 ttcagtgcaa tgctatgact ttggatggtc ccctagtttt ccgacatgta aaggtcaagt
      841 aagatcatgt ggtcaatatc ctgaactact caatggggaa ataaagggaa caaagaaagc
      901 tgaatacagc catggtgacg tggtggagta tgattgcaaa cctagatttc tactgaaggg
      961 acccaataaa atccagtgtg ttgacgggaa gtggacaacc ttgccgacat gcgttgagga
     1021 gaaaagaaca tgtggagaca ttcctgcact tgagcatggc tctgtcaagt tttctgtccc
     1081 tccctaccac cacggagatt cagtggagtt tacttgtgca gaaaccttca caatgattgg
     1141 acagagatca gtttcttgca ttagtgggag gtgggcccag cttcctcgat gtgttgcaac
     1201 agtacaactt gagaagtgta aagcaccgag actggctgta ataggggcaa ataaactcga
     1261 gaaggatgga ttgaatcata actctagcat cagttacaaa tgtagaggaa gtcagaagta
     1321 tggatattca atctgcatta atggaagatg ggatcctgaa ccaacctgta caagaaaaga
     1381 gaaagcattc tgccctcctc ccccacagat tccaaatgcc caagtgattg ataccacagt
     1441 gaaatacttg gatggagaga aagtatctgt tctttgccaa gatggttacc taactcaggg
     1501 cccagaagaa atggtgtgta aacatggaag gtggcagtcg ttaccacgct gcacggcaaa
     1561 aattacatgt tcccagcccc ctaaaataga ccacggatct attaagttac ccagattgtc
     1621 agatgcagga agagatgcaa ttgactccag cagtcatgaa cacggaacca cattcagcta
     1681 tgtctgtgat gatggcttca gaatatctaa ggaaaatggg gtaacctgcc acatgggaaa
     1741 atggagctct ccgcctcgat gtgttgaatc aacagggaaa tgtgggcctc ctccaactat
     1801 tgaaaatgga gacatcacct ccttgtcatt accagtatat gcaccgttat catcagttga
     1861 atatcaatgc caatccttct ataaaatgca gggcagcaag aaaataacct gcaaaaatgg
     1921 agagtgggaa gagccaccaa aatgtttaca tgcatgtgta ttaacagaag aaattatgag
     1981 aagacagaac ataattccca agaggacaaa gaataaaaag atttatatcc agtcagggga
     2041 ttatgttgaa tttgtgtgtc taactgcata tcaaaaggca caaggatcac ctgagtttcg
     2101 tacacagtgc attgatggtc acatcaatta tcccacctgc tcaaaataag ttacaactct
     2161 tagtagactt cataaatgat catttgtttt gaaaggtgtg taaactattg ctaacacagt
     2221 ttcaaattac atttggaata ttaacatatt tcttccataa gtgcaaagtt ctgttgacga
     2281 atggtgatta atttggacat gagagacagc tgccacaaat gcaaaagcag agcattggaa
     2341 actcctgatc caaaagggat ttgtctagcc tcaaatcaat gacagaatta gatgcaactg
     2401 ctttagtgtc tgtttctatc cagcactttc ttaagttgct ccaatcatga tgctaccttt
     2461 gtatctcaat ctctgattca cagtgaatgg aagatgtatt gtctcagtct tcaaattagt
     2521 attagttcac aaacatgtaa caactgaatt gacagattta acactataaa tgaatacacg
     2581 taagtgttac ataattcttt tgtagtgata ataaatctaa aaagtatttg tacataaatt
     2641 tctaaaataa tgatatggcc catggaaact ttcagatggt tatagaatta aattaaaata
     2701 caactgggta tacga
//
