LOCUS       NM_001007746            2044 bp    mRNA    linear   ROD 12-APR-2024
DEFINITION  Rattus norvegicus cilia and flagella associated protein 418
            (Cfap418), transcript variant 1, mRNA.
ACCESSION   NM_001007746 XM_342802
VERSION     NM_001007746.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2044)
  AUTHORS   Sharif,A.S., Yu,D., Loertscher,S., Austin,R., Nguyen,K.,
            Mathur,P.D., Clark,A.M., Zou,J., Lobanova,E.S., Arshavsky,V.Y. and
            Yang,J.
  TITLE     C8ORF37 Is Required for Photoreceptor Outer Segment Disc
            Morphogenesis by Maintaining Outer Segment Membrane Protein
            Homeostasis
  JOURNAL   J Neurosci 38 (13), 3160-3176 (2018)
   PUBMED   29440555
REFERENCE   2  (bases 1 to 2044)
  AUTHORS   Estrada-Cuzcano,A., Neveling,K., Kohl,S., Banin,E.,
            Rotenstreich,Y., Sharon,D., Falik-Zaccai,T.C., Hipp,S., Roepman,R.,
            Wissinger,B., Letteboer,S.J., Mans,D.A., Blokland,E.A., Kwint,M.P.,
            Gijsen,S.J., van Huet,R.A., Collin,R.W., Scheffer,H., Veltman,J.A.,
            Zrenner,E., den Hollander,A.I., Klevering,B.J. and Cremers,F.P.
  CONSRTM   European Retinal Disease Consortium
  TITLE     Mutations in C8orf37, encoding a ciliary protein, are associated
            with autosomal-recessive retinal dystrophies with early macular
            involvement
  JOURNAL   Am J Hum Genet 90 (1), 102-109 (2012)
   PUBMED   22177090
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079168.1.
            
            On Nov 29, 2004 this sequence version replaced XM_342802.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK478606.1, DY318669.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2044
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q13"
     gene            1..2044
                     /gene="Cfap418"
                     /note="cilia and flagella associated protein 418"
                     /db_xref="GeneID:362483"
                     /db_xref="RGD:1549749"
     exon            1..262
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..734
                     /gene="Cfap418"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C8orf37 homolog"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 418
                     isoform 1"
                     /protein_id="NP_001007747.1"
                     /db_xref="GeneID:362483"
                     /db_xref="RGD:1549749"
                     /translation="MAKDLDELLDEVETKFCRLDPLRLDLGERPKGGSGGGGTHSGDR
                     NGAQEKDTLRSTETFKKEDDLDSLINEIFEEPNFDKKSFQKFKSKSSSNTSVRAPIQG
                     LSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCVACDFQIVSYNDYMWDKSCDYLFFR
                     NNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQADHELRWVCGKH"
     exon            263..350
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
     exon            351..418
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
     exon            419..484
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
     exon            485..580
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
     exon            581..2021
                     /gene="Cfap418"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatgggggca ggggacccgc tcgcgggcgc gacggtttct cacgttgcct tggagaccac
       61 ccgccagcct ggctccagag ggaaagacgt gtctgtccaa gatggcgaag gacctggacg
      121 agcttctgga tgaagtcgag accaagttct gcagactcga ccccttgagg ctggacctgg
      181 gtgagcggcc caaaggcggc agcggcggcg gcggcacgca cagcggcgac cggaacggag
      241 cccaggagaa agacactctc agatcaacag aaacatttaa aaaggaagat gatctcgaca
      301 gtcttattaa tgaaatattt gaggagccta actttgacaa aaaatctttt caaaaattta
      361 aatctaaatc ttcaagtaac acatctgtca gagctcccat tcaaggcctc agtaaaagtt
      421 gcagtcctgt gtatctcagt ggaagcgcca ttccatgtgg gattggaaca aatacttcac
      481 agagagcatg tgaccgactg cgttgtgtag cctgtgactt ccagatagtg agctacaatg
      541 actatatgtg ggacaagtca tgtgattacc tgttcttcag aaacaacatg ccagaattcc
      601 acaaactcaa aacaaagttg atcgagaaga agggagcacg ggcatatgcc tgccagtgta
      661 gctggagaac tgtggaagag ctcactgacc tgcaggcaga ccatgagctc cgctgggtct
      721 gtggtaaaca ctgaatgcag accattcagg ttccaatagc tgcactggga agaacatgtt
      781 ccacgcacca aacttgggca ccagtacacg gcagtattgt gccctttggg aagaggcaac
      841 aagttttgtg taacttcaca cacttttgaa gaccaaatgg actgggaaag acatatgtac
      901 tgtgacacct tggcattctt ccttttgaca tggacatttt acttagaagg ttaaaatatc
      961 tgtgttcacc agtctgtctc cttttaagga ttgaaacttt gacattttgt gcaaatttac
     1021 agctttcccg cagcaactgc catactgact gctaatccac tccatacggt cctcgtgtat
     1081 cattgtcatt aaagagggca gaggggtcat tgtgtatgag tgttcatggc tcttcctttt
     1141 ctgatccatc attatcagag accataaggt ggacatgaca aaaaagtaga tgacattagt
     1201 tactgagggg ttgtcaagag tgcagggaac attgtaaccc tttctcacat atatctcttc
     1261 ttgcctcacc aactcaactc agtattgtgt gtaatagtaa taatgatgtt ccagttttag
     1321 cacatttccc tcctttgctc atcgaaatat caaaagttgt tagttttcta ttagcaaaca
     1381 tctgtttata aaagattttt gatgcaactg aagtcactaa aatcttacaa ataagtcact
     1441 gctaggcttt tcaagtatct tccgcaactc tacgtgagca gcggtacgat ggcgttcaga
     1501 tgacctgcag actttctaat agtatccggt cggtccattc tttattgaaa tatagagaac
     1561 aaatgggtag tcattgggct cccgtgatat cactgagatg ggaggaaccg tatcatagta
     1621 acatgcatta cctcagttta tgtcccagcc ccatgtgtgc ctacttcctg agtgcgagtt
     1681 agtgtgggac acagggcact ctgaaagggt gcacatatga tctgactggt tttctcttaa
     1741 ctccattctc aacaccaagc aaagcctctg atggctgaag gtttcctcct aggctcgggg
     1801 tctcgctcag caatagcgtg tgcattgcgt gcatgaggcc ctcagtttat tcctgtagac
     1861 aaaagaagac aaagaggcaa gcttttcctg actctgacac atttgtgtac tgaaaaacct
     1921 ttaattgcag caaaagagat ctcaaagtag ctgatgcttg aatttttgta tgtagataga
     1981 tttacaagtt ttctttcaat aaacctattt actcctcaaa aaaaaaaaaa aaaaaaaaaa
     2041 aaaa
//
