LOCUS       XM_039098134            1848 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus carboxylesterase 3a (Ces3a), mRNA.
ACCESSION   XM_039098134
VERSION     XM_039098134.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq; corrected model.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051354.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039098134.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            frameshifts          :: corrected 4 indels
            internal stop codons :: corrected 2 genomic stop codons
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-247               JACYVU010000313.1  10037756-10038002
            248-282             JACYVU010000313.1  10039152-10039186
            283-283             "N"                1-1
            284-378             JACYVU010000313.1  10039187-10039281
            379-379             "N"                1-1
            380-405             JACYVU010000313.1  10039282-10039307
            406-406             "N"                1-1
            407-452             JACYVU010000313.1  10039308-10039353
            453-549             JACYVU010000313.1  10039461-10039557
            550-551             "NN"               1-2
            552-579             JACYVU010000313.1  10039558-10039585
            580-713             JACYVU010000313.1  10039743-10039876
            714-869             JACYVU010000313.1  10040511-10040666
            870-972             JACYVU010000313.1  10040772-10040874
            973-1062            JACYVU010000313.1  10041285-10041374
            1063-1200           JACYVU010000313.1  10041470-10041607
            1201-1281           JACYVU010000313.1  10043371-10043451
            1282-1429           JACYVU010000313.1  10044181-10044328
            1430-1579           JACYVU010000313.1  10045319-10045468
            1580-1655           JACYVU010000313.1  10045589-10045664
            1656-1848           JACYVU010000313.1  10045740-10045932
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1848
                     /gene="Ces3a"
                     /note="carboxylesterase 3a; The sequence of the model
                     RefSeq transcript was modified relative to its source
                     genomic sequence to represent the inferred CDS: inserted 5
                     bases in 4 codons; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 7 Proteins, and 20%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:689754"
                     /db_xref="RGD:1588734"
     CDS             157..1848
                     /gene="Ces3a"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: inserted 5 bases in 4 codons;
                     substituted 2 bases at 2 genomic stop codons"
                     /codon_start=1
                     /transl_except=(pos:958..960,aa:OTHER)
                     /transl_except=(pos:964..966,aa:OTHER)
                     /product="LOW QUALITY PROTEIN: carboxylesterase 3"
                     /protein_id="XP_038954062.1"
                     /db_xref="GeneID:689754"
                     /db_xref="RGD:1588734"
                     /translation="MTNMGTTVRAGSSVLLWVIYLFLVFPTTVTGPKVPQPEMDTPXG
                     HVQGQQVGVKNTEHVVNVFLSIPFAQAPLGXLQFSVPLPXQPWEGVRVASTNLPMCLQ
                     DVERMNSSRFTPNEKHLIFPISEDCLILSXEITAGTKRLVMVWIHGESLEVGSATAQD
                     GSALAAYGGVVVVTVQYHLRIFGFLSTGDKHMPSNRGFLDVVAALCWIQGNIAPFGGE
                     PNCVTVFGNSAGGSIVSSLVLSPMFAGLSHRAISQSGVITTRMMKEMNTXPXARNFAN
                     SVACSSGSPAELVQCLLQKEEKDLIQKNVNVSYIINDSFPQRPEKILTDRQLPTVPYL
                     LGVTNHEFGWLILRIWNILDKLEHLSPEDLLDISRPFLALMEVPPEIMPTVIDQYLDN
                     GSDESATKYAFQELLGDITLIIPILNFSKYLQDAGCPVLLYEFQNTPNSFAKFKSAWV
                     KAEHASENSFVFGGPFLIEESSLLAFPEATEEEKQLSLTMIAQWSQSHTGNPNGKELP
                     PWPQLNQLEQYLEVGLEPQTGVKLKKGRLQFWTETLPRKIQEWHRQQRRRNLEEL"
ORIGIN      
        1 agaaggtcct gtactgggag caggcagagc acagcatact taattccata gctggtcacc
       61 atccaatcgg gacagaccag gttaattttc acaagataag agtcactata aggtcaagtc
      121 ctctccagct ttccacagct tcttccatag ttggttatga caaatatggg gacaacggta
      181 cgagctgggt ccagtgtcct actctgggtg atctatctgt tcctggtatt tcctaccaca
      241 gtcactggac ccaaagtccc tcagcctgaa atggataccc ctntgggtca tgttcaaggc
      301 cagcaggtag gtgtgaagaa tacagagcac gtggtaaatg tcttcctgag cattcccttt
      361 gctcaggcac cactaggant gcttcagttc tcggttccac tcccancaca gccctgggaa
      421 ggtgtgagag ttgccagcac caatctccca atgtgtctgc aggatgtaga gagaatgaac
      481 agcagcagat tcacccccaa cgaaaagcac ctaatcttcc ctatttctga ggactgcctg
      541 atcctcagcn ntgagatcac tgcagggacc aaaaggctgg tcatggtatg gatccatggg
      601 gaatctctgg aagttggctc cgccaccgct caggacggat cagccctggc tgcctatggg
      661 ggtgtggtag tcgtcactgt ccagtatcac cttaggatct ttggcttcct cagcactggg
      721 gataagcaca tgccaagcaa cagggggttc ctggatgtgg tggctgctct gtgctggatc
      781 caggggaaca tagccccctt tgggggtgaa cccaactgtg tcactgtctt cggtaattct
      841 gctggtggct ctatcgtctc atccctggtc ctgtctccaa tgtttgctgg gctctcccac
      901 agagccatat cccagagtgg ggttatcacc accaggatga tgaaagagat gaacacatag
      961 ccttaagctc ggaactttgc caattctgtg gcctgtagtt ctggatcccc agctgagctg
     1021 gtacagtgtt tgctgcagaa ggaagaaaag gatcttatac agaaaaatgt gaacgtttcc
     1081 tatatcatta atgactcctt cccacaaagg ccagagaaga tcctcacaga tcggcaactc
     1141 cccactgtgc cctacctcct gggagtcacc aaccatgagt ttggctggct catactcagg
     1201 atctggaata tcctggataa gttggaacat ttgagcccgg aggacctatt agatatttca
     1261 aggcctttct tggcccttat ggaagtgccc cctgagatca tgcccactgt catagatcaa
     1321 tacctagaca atggctcaga tgaatcagct acaaagtatg ccttccagga attgctgggt
     1381 gatatcacac tcatcattcc tatcttgaac ttctcaaaat accttcaaga tgctgggtgc
     1441 cctgttctct tgtatgagtt ccagaataca cccaattctt ttgcgaagtt caagtcagcc
     1501 tgggtgaagg ctgaacatgc atctgagaat tcctttgttt ttggaggtcc tttcctcatt
     1561 gaagagagct ccctcctggc cttcccagag gccacagagg aagagaagca gctgagccta
     1621 accatgatag cccagtggag ccagtcgcac acagggaacc ccaatggcaa ggagctacct
     1681 ccttggcccc aattaaacca gttagaacaa tacttggagg ttggtctaga accacagact
     1741 ggggtgaagc taaagaaggg tcggctacag ttctggacag agacactgcc cagaaaaatt
     1801 caagaatggc accggcagca gaggagaagg aatctggagg agctctga
//
