LOCUS       NM_001190369            1957 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus carboxylesterase 2 (Ces2), mRNA.
ACCESSION   NM_001190369 NM_001271303 XM_002725369
VERSION     NM_001190369.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1957)
  AUTHORS   Holmes,R.S., Glenn,J.P., VandeBerg,J.L. and Cox,L.A.
  TITLE     Baboon carboxylesterases 1 and 2: sequences, structures and
            phylogenetic relationships with human and other primate
            carboxylesterases
  JOURNAL   J Med Primatol 38 (1), 27-38 (2009)
   PUBMED   19187434
REFERENCE   2  (bases 1 to 1957)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474006.1.
            
            On or before Mar 21, 2022 this sequence version replaced
            NM_001271303.1, XM_002725369.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5756307, SAMEA5760400
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1957
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p14"
     gene            1..1957
                     /gene="Ces2"
                     /note="carboxylesterase 2"
                     /db_xref="GeneID:100910144"
                     /db_xref="RGD:6504334"
     exon            1..125
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1735
                     /gene="Ces2"
                     /EC_number="3.1.1.1"
                     /note="carboxylesterase-like"
                     /codon_start=1
                     /product="carboxylesterase 2 precursor"
                     /protein_id="NP_001177298.1"
                     /db_xref="GeneID:100910144"
                     /db_xref="RGD:6504334"
                     /translation="MPRNQLHSWLNAVLFGLLLLLIHVQGQDSPESSPIRTTHTGQVQ
                     GKLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEPPEPWSGVRDATSQPAMCLQNLD
                     ILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNLPVMVWIHGGALVVGMASM
                     YDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFG
                     GNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTV
                     AKLSGCEAMDSEALVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDF
                     HPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLM
                     EEYMGNTDDSQTLQIQYTEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNV
                     RPPHVKADHADEVPFVFGSFFSGMKLDFTEEERLLSRRMMKYWANFARQGNPNSEGLP
                     YWPALDHDEQYLQLDTHPAVDRALKARRLQFWTKTLPQKIEELNGAQKNHAEL"
     exon            126..336
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            337..478
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            479..612
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            613..871
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            872..970
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1111
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            1112..1192
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1337
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1475
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1548
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1957
                     /gene="Ces2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgaaacttg gtcattctag cagcacagac tcagaactga gagctgatca tgccacggaa
       61 ccaactgcat agctggctga atgctgtgct ctttgggctg ctgcttcttc ttattcatgt
      121 gcagggtcag gactcaccgg agtccagccc catcaggacc acacacactg gccaggtcca
      181 aggcaagctc gaccacgtga aggacactaa agctggtgtc cacaccttcc tgggaattcc
      241 ctttgccaag cctcctgtag gaccgctgcg ctttgcacct cctgagccac ctgagccatg
      301 gagtggtgtg agagatgcga cctcacagcc ggccatgtgt ctgcaaaatc ttgatattct
      361 ggatgaagta ggcctgctgg atatgaaaat gatactgtct tccatttcta tgtctgagga
      421 ctgcctgtat ctcaatgtct atgcaccagc ccatgcccgt gagggctcta acctgcctgt
      481 gatggtgtgg atccacggag gtgcgctggt tgtaggaatg gcttccatgt atgatggatc
      541 tctattgaca gtcaatgagg acttggtggt tgtcactatt cagtatcgtc tgggtgtcct
      601 gggctttttc agcactggag atgagcacgc cagaggcaac tggggatacc tggaccaagt
      661 ggctgcccta cgttgggtcc agcagaatat cgcccatttt ggaggcaacc ctaaccgtgt
      721 cactatcttt ggcgagtctg caggtggcac aagtgtgtct tcacatgtta tatcccccat
      781 gtctcaaggg ctcttccatg gtgccatcat ggagagtgga gtggccctgc tgcctgacct
      841 tatctctgaa acctctgaaa cggtctccac tacagtggcc aagctctctg gatgtgaggc
      901 tatggactca gaggccctgg tgcgctgcct gagagcgaag agtggagcag agattctggt
      961 cattaacaag gtcttcaaga tgatccccgc tgtggtggat ggagagttcc tacccaggca
     1021 tcccaaagag ctgttggcat ctgaggattt tcaccctgtc cccagcatca ttggtgttaa
     1081 cacagatgag tactgttgca ccattcctat ggtcatgggc actgctcaaa taataaagga
     1141 gctatccaga gagaacctgc aggctgttct aaaggataca gcagcacaaa tgatgcttcc
     1201 tcctgagtgt ggtgacctgc tcatggaaga gtacatgggg aacactgatg attcccagac
     1261 cctacaaata cagtacacag agatgatggg agacttcctg tttgtgatcc ctgcactcca
     1321 agtagcacac tttcagcgtt cccatgcccc tgtctacttc tatgagttcc aacatgcacc
     1381 cagctatttc aagaatgtca ggccacccca cgtgaaggct gaccatgctg atgaggttcc
     1441 ttttgtcttt gggtccttct tttcgggcat gaaacttgac ttcactgagg aggagaggct
     1501 gctgagcagg aggatgatga agtactgggc caactttgca agacagggga accccaacag
     1561 cgagggtcta ccctactggc ctgcattgga ccacgatgag cagtacctgc agttggacac
     1621 ccatcctgct gtggaccgag ccctgaaggc cagaaggctg cagttctgga ccaagactct
     1681 gccccagaag attgaggagc taaatggagc tcagaaaaac catgcagagc tgtagtgtct
     1741 ggtgaaagga acagagtgtg ggagtgaggg caggtgggat cattctgagt ttcaaagtct
     1801 aattttttgt tccaacactc agaatccttt ccaatcccaa tattttccct ttccaacatg
     1861 aatgagaagc cctccatgtg ttactcttta ttcttccgag caaactttaa ttggactcaa
     1921 taaaagttcc cataatagtg tggatatatg aatccta
//
