LOCUS       NP_001007700             416 aa            linear   ROD 07-OCT-2024
DEFINITION  choline/ethanolaminephosphotransferase 1 [Rattus norvegicus].
ACCESSION   NP_001007700 XP_227571
VERSION     NP_001007700.1
DBSOURCE    REFSEQ: accession NM_001007699.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 416)
  AUTHORS   Butler,P.L. and Mallampalli,R.K.
  TITLE     Cross-talk between remodeling and de novo pathways maintains
            phospholipid balance through ubiquitination
  JOURNAL   J Biol Chem 285 (9), 6246-6258 (2010)
   PUBMED   20018880
REFERENCE   2  (residues 1 to 416)
  AUTHORS   Kulinski,A., Rustaeus,S. and Vance,J.E.
  TITLE     Microsomal triacylglycerol transfer protein is required for lumenal
            accretion of triacylglycerol not associated with ApoB, as well as
            for ApoB lipidation
  JOURNAL   J Biol Chem 277 (35), 31516-31525 (2002)
   PUBMED   12072432
REFERENCE   3  (residues 1 to 416)
  AUTHORS   Wright,M.M. and McMaster,C.R.
  TITLE     PC and PE synthesis: mixed micellar analysis of the
            cholinephosphotransferase and ethanolaminephosphotransferase
            activities of human choline/ethanolamine phosphotransferase 1
            (CEPT1)
  JOURNAL   Lipids 37 (7), 663-672 (2002)
   PUBMED   12216837
REFERENCE   4  (residues 1 to 416)
  AUTHORS   Henneberry,A.L. and McMaster,C.R.
  TITLE     Cloning and expression of a human
            choline/ethanolaminephosphotransferase: synthesis of
            phosphatidylcholine and phosphatidylethanolamine
  JOURNAL   Biochem J 339 (Pt 2) (Pt 2), 291-298 (1999)
   PUBMED   10191259
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079471.1.
            
            On Nov 29, 2004 this sequence version replaced XP_227571.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079471.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..416
                     /product="choline/ethanolaminephosphotransferase 1"
                     /EC_number="2.7.8.2"
                     /EC_number="2.7.8.1"
                     /EC_number="2.7.8.22"
                     /note="1-alkenyl-2-acylglycerol choline
                     phosphotransferase"
                     /calculated_mol_wt=46368
     Region          1..20
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            18
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9Y6K0; propagated from
                     UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            40
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9Y6K0; propagated from
                     UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Region          43..411
                     /region_name="PRK10832"
                     /note="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase; cl00453"
                     /db_xref="CDD:469774"
     Site            89..108
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            116..133
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            144
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            151
                     /site_type="other"
                     /note="Increases basicity of active site His.
                     /evidence=ECO:0000250|UniProtKB:Q4KLV1; propagated from
                     UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            156..176
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            180..199
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            210..230
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            246..267
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            286..306
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            315..334
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            349..363
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     Site            368..388
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AXM5.1)"
     CDS             1..416
                     /gene="Cept1"
                     /coded_by="NM_001007699.1:231..1481"
                     /db_xref="GeneID:310773"
                     /db_xref="RGD:1359727"
ORIGIN      
        1 msghrstrkr cgdshpespv gfghmsttgc ilnklfqlpt pplsrhqlkr leehryqsag
       61 rslleplmqg ywewlvgrvp swiapnliti iglsinictt illvfycpta teqaplwayi
      121 acacglfiyq sldaidgkqa rrtnsssplg elfdhgcdsl stvfvvlgtc iavqlgtnpd
      181 wmffccfagt fmfycahwqt yvsgtlrfgi idvtevqifi iimhllavig gppfwqsmip
      241 vlniqmklfp alctvagtif sctnyfrvif tggvgkngst iagtsvlspf lhigsvitla
      301 vmiykksavq lfekhpclyi ltfgfvsaki tnklvvahmt ksemhlhdta figpallfld
      361 qyfnsfidey ivlwialvfs ffdlirycvs vcnqiashlh ihvfriktst ahsnhh
//
