LOCUS       NP_001100566             845 aa            linear   ROD 23-MAR-2023
DEFINITION  centrosomal protein of 97 kDa [Rattus norvegicus].
ACCESSION   NP_001100566 XP_001062300 XP_221540
VERSION     NP_001100566.1
DBSOURCE    REFSEQ: accession NM_001107096.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 845)
  AUTHORS   Kobayashi T, Kim S, Lin YC, Inoue T and Dynlacht BD.
  TITLE     The CP110-interacting proteins Talpid3 and Cep290 play overlapping
            and distinct roles in cilia assembly
  JOURNAL   J Cell Biol 204 (2), 215-229 (2014)
   PUBMED   24421332
REFERENCE   2  (residues 1 to 845)
  AUTHORS   Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I,
            Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA
            and Andersen JS.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   3  (residues 1 to 845)
  AUTHORS   Spektor A, Tsang WY, Khoo D and Dynlacht BD.
  TITLE     Cep97 and CP110 suppress a cilia assembly program
  JOURNAL   Cell 130 (4), 678-690 (2007)
   PUBMED   17719545
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_221540.2, XP_001062300.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132264 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     Protein         1..845
                     /product="centrosomal protein of 97 kDa"
                     /note="leucine-rich repeats and IQ motif containing 2;
                     centrosomal protein 97kDa"
                     /calculated_mol_wt=94064
     Region          17..37
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          18..242
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          38..59
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          60..81
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          82..103
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          104..125
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          126..149
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          150..171
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          172..196
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          540..>560
                     /region_name="IQCD"
                     /note="IQ (isoleucine-glutamine) motif containing D
                     (IQCD); cd23767"
                     /db_xref="CDD:467745"
     CDS             1..845
                     /gene="Cep97"
                     /gene_synonym="Lrriq2; RGD1307400"
                     /coded_by="NM_001107096.1:62..2599"
                     /db_xref="GeneID:304007"
                     /db_xref="RGD:1307400"
ORIGIN      
        1 mavarvdgal apgegsvvnw sgqglqklga nlpcdadvht lildknqiik lenlekckql
       61 iqlsvannrl vrmmgvaklt qlrvlnlphn sigcmeglkd lvhlewlnla gnnlktmeqi
      121 nscsalqhld lsdnnipqig dvskltalkt lllhgniits lrmapaylpr nlsilslaen
      181 eirdlneisf laslseleql simnnpcvma tpsipgfdyr pyivswclnl rvldgyvisq
      241 keslkaewly sqgkgrsyrp gqhvqlvqyl atvcplisal glqtaedakl ekilskqrfh
      301 qrqlmnqsqn eelspiaave trvprtpecs spvqdfqese pvlqinswvg sssnddqlya
      361 vknnflatth atrysrndlh lediqtdedk lncsllsses tfmpvasgls pvsptvelrl
      421 qginlgledd dgtdeftkgl ehqdldkdre kslwdsdvqm lkrkistegn eeagllpcpk
      481 ssiitallke dnhsltsggh svshtepnre evmspttsek fpcriftqrp valgqdkvtl
      541 qklnaaatkl qacwrgfytr nynpqakgvr yeirlrrmqe hivcltdevr rlrkerdeer
      601 vknfvqeeav rvlwnevral qawqqtveqr lvswhsdvpp isstlvspkp pllpqhqdps
      661 sdqnsdwlii eddapqeksv pdfpdsgfhs slteqvhclq dsldfekssv essensalgn
      721 sadtvkyvkd pdseataeeh sdcskessts eqdntllqqy lasvqqldda ddragpddma
      781 gdnkrllacs perlgasdse ahrasptlqe eisqtpenck lneevqgqpp ecdtafqvlq
      841 vgvtv
//
