LOCUS       NM_001394861            2605 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus centrosomal protein 89 (Cep89), mRNA.
ACCESSION   NM_001394861 XM_006228881
VERSION     NM_001394861.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2605)
  AUTHORS   Ye,X., Zeng,H., Ning,G., Reiter,J.F. and Liu,A.
  TITLE     C2cd3 is critical for centriolar distal appendage assembly and
            ciliary vesicle docking in mammals
  JOURNAL   Proc Natl Acad Sci U S A 111 (6), 2164-2169 (2014)
   PUBMED   24469809
REFERENCE   2  (bases 1 to 2605)
  AUTHORS   Sillibourne,J.E., Hurbain,I., Grand-Perret,T., Goud,B., Tran,P. and
            Bornens,M.
  TITLE     Primary ciliogenesis requires the distal appendage component Cep123
  JOURNAL   Biol Open 2 (6), 535-545 (2013)
   PUBMED   23789104
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2605)
  AUTHORS   Tanos,B.E., Yang,H.J., Soni,R., Wang,W.J., Macaluso,F.P.,
            Asara,J.M. and Tsou,M.F.
  TITLE     Centriole distal appendages promote membrane docking, leading to
            cilia initiation
  JOURNAL   Genes Dev 27 (2), 163-168 (2013)
   PUBMED   23348840
REFERENCE   4  (bases 1 to 2605)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On May 7, 2021 this sequence version replaced XM_006228881.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.1543.1,
                                           SRR26643288.2100.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-136               JAXUCZ010000001.1  97195137-97195272
            137-243             JAXUCZ010000001.1  97199402-97199508
            244-402             JAXUCZ010000001.1  97202838-97202996
            403-583             JAXUCZ010000001.1  97204766-97204946
            584-689             JAXUCZ010000001.1  97208278-97208383
            690-718             JAXUCZ010000001.1  97210334-97210362
            719-761             JAXUCZ010000001.1  97212414-97212456
            762-980             JAXUCZ010000001.1  97213815-97214033
            981-1123            JAXUCZ010000001.1  97214338-97214480
            1124-1174           JAXUCZ010000001.1  97217123-97217173
            1175-1258           JAXUCZ010000001.1  97217608-97217691
            1259-1362           JAXUCZ010000001.1  97219780-97219883
            1363-1478           JAXUCZ010000001.1  97222643-97222758
            1479-1659           JAXUCZ010000001.1  97226247-97226427
            1660-1827           JAXUCZ010000001.1  97226806-97226973
            1828-1969           JAXUCZ010000001.1  97227868-97228009
            1970-2059           JAXUCZ010000001.1  97231355-97231444
            2060-2229           JAXUCZ010000001.1  97233686-97233855
            2230-2605           JAXUCZ010000001.1  97236640-97237015
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2605
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /note="centrosomal protein 89"
                     /db_xref="GeneID:292811"
                     /db_xref="RGD:1311730"
     exon            1..136
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..2470
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /note="coiled-coil domain containing 123; centrosomal
                     protein 89kDa"
                     /codon_start=1
                     /product="centrosomal protein of 89 kDa"
                     /protein_id="NP_001381790.1"
                     /db_xref="GeneID:292811"
                     /db_xref="RGD:1311730"
                     /translation="MLLSFRRNRRSQFNHIIHGFLPAASIAPKPAVPRTPPPRSPNPS
                     PERPRSALAAAILATTLTGQTVAIPQPRQRSRSESDASQVEKDSFIEPYATTSELRLR
                     QSWQNEPKRTSLPSFETLGYREDEDAETQVSSSCRESESTTWKDVGDGRGAAYAVPLR
                     RQVSSSQKLVRKGDASEQDWLSDSSSSSSTPQDTQQKDVKPSVPNLEDEKVPLCKKTP
                     PSPDVAGRIHQRYTKITKEKFDELKEETVHLYTANQALSLELSTLRQAMKDLQLKLKI
                     VEKDNRKLKETEKASSQEVVTPELLCLRKQSQDLVDENEGLKMIIHRLNVELSRYQTK
                     FRPLSEEESSYIEGLPSKGPTPPWLVDIKYLSPLLLAYEDRMKEKDKLSTALEEEMKT
                     FRLRVQEVVRENEGLHQELTKRSPVTIEEWRQLQTQAELVLDENKLLIEQLEIQQTKA
                     KDTQQAHLRDVSKLTKQLVLLEAKTQSQEKQLMESKEQLESLEARCRELKTQLDSKIA
                     PDVHTSIVNELKSQLQKEEEKDSAEMEELMGKLTALQVQKKSLLLEKSSWATSNRALE
                     AELELTRKANRRYQKKIGVLRKQVEKAMGKEMSAHQYLANLVGLAENVTKERDSLKYL
                     AQCLEIEKHGVLNKILKGNIRLGRLEERVKGYKKQAALKLGDIHHRLMEQQDDFAGKA
                     AQYQKEVKHLHHMLQRKQEVLDEALQQKRNMEGELEMVLESTAKENRRMRGLLQAALQ
                     RKGIQCATAPQDTCLSRLSQGDLLIGHDFSYGDVQLPATRVCQSLGESVA"
     exon            137..243
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            244..402
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            403..583
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            584..689
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            690..718
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            719..761
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            762..980
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1123
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1174
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1258
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1362
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1478
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1659
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1827
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1969
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2059
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2229
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
     exon            2230..2605
                     /gene="Cep89"
                     /gene_synonym="Ccdc123; RGD1311730"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccgcggga gctagactgt ggggagctgt gcaggctgcg gggctgtctt ccagccagtc
       61 cagcaccagg cgcctcagcc cgcagccctc agccaggatg ctcctcagct tccgcaggaa
      121 ccgccggagc cagttcaacc acatcatcca tggcttcctc cctgcagcca gcattgctcc
      181 gaagccagct gtgccacgca caccccctcc ccgaagcccc aacccctctc cagagaggcc
      241 cagatctgct ctggctgcag ccatcctggc aaccaccttg actggacaga cagttgccat
      301 tcctcagcct cgccagagat cccggtctga gagtgatgcc tcccaagttg aaaaggacag
      361 cttcatcgag ccatatgcca ccacctcaga gctgaggctt cggcaaagct ggcagaatga
      421 gccgaaaagg acttccttgc cgtcctttga gacgttgggc taccgggagg atgaagatgc
      481 tgaaacacag gtgtccagca gctgcaggga gtcggagtcc accacctgga aggatgtggg
      541 agacggcaga ggtgcagcgt acgctgtgcc tctcaggcgt caggtatcgt cgtcacaaaa
      601 gctggtgaga aaaggtgatg cttctgagca agactggctt tcagactcct cctcctcctc
      661 ctccacaccg caggacactc aacagaaaga tgttaagccc tctgttccga atctagagga
      721 tgagaaagta ccactgtgta aaaagacccc tccctctcca gatgtagctg gtagaataca
      781 tcaaagatat acaaaaataa ccaaagaaaa gtttgacgag ttaaaagaag aaacagtgca
      841 tctttacact gcaaaccaag ccctcagcct tgaactgagc actctgagac aggcaatgaa
      901 ggacttacag ctgaagctca agatagtgga aaaagacaac aggaagctga aggaaacaga
      961 aaaggcctcc tctcaggaag tagtcacacc tgaattgctt tgcttaagga agcaaagcca
     1021 agacctggtg gatgagaacg agggcctgaa gatgattatc catcgcctga atgtagaact
     1081 cagtcgctac cagacaaaat tccggccttt gtctgaggaa gagagttcct atattgaagg
     1141 cctcccatct aagggcccca cacccccctg gttggtggat ataaagtacc tctcacccct
     1201 gttgctggct tatgaagaca gaatgaaaga aaaggacaaa ctcagcaccg ccctggagga
     1261 ggaaatgaaa acctttagac tgcgagtcca agaagtggtg agggaaaatg aaggcttgca
     1321 ccaagagtta actaagagaa gccccgtcac catcgaggaa tggaggcagc ttcagactca
     1381 agcagagctg gttctagatg agaacaagct cttgatagag cagttggaga tccagcaaac
     1441 gaaagccaag gacacccagc aggcgcacct ccgggacgtt tctaagctga ctaaacaact
     1501 tgtgctcctg gaggcaaaga ctcagagcca ggaaaagcag ctcatggaaa gcaaggagca
     1561 gctggagagc ttggaggcca gatgccgaga gctcaagaca cagctggata gcaagatcgc
     1621 accagacgtc cacacatcaa ttgtcaatga actaaaaagc cagttgcaaa aggaagaaga
     1681 gaaagacagt gctgagatgg aggagctgat gggaaagctg acagccctgc aggtgcagaa
     1741 gaagagcctg cttctggaga agagcagctg ggccaccagc aacagagcac tagaggctga
     1801 gctggagctc acacgcaagg ccaacaggcg ataccaaaag aagattggtg tcctcagaaa
     1861 gcaggtagaa aaggccatgg ggaaggagat gtccgctcac cagtacctgg caaacctggt
     1921 gggcttggca gagaatgtca ccaaggaacg agacagtctt aagtatttgg ctcagtgttt
     1981 agagatcgag aagcacgggg tcctcaacaa aatcctgaaa ggcaacattc gcctgggcag
     2041 gctggaggaa agggtaaagg ggtacaagaa gcaggcggca ctgaagctgg gggacatcca
     2101 tcaccgcctg atggagcagc aggacgactt tgctggcaaa gcagcccagt accagaagga
     2161 ggtgaagcac ctgcaccaca tgctgcagag gaagcaggag gtcctggatg aggcactgca
     2221 gcagaaaaga aatatggaag gtgagcttga aatggtcctg gagtccactg ccaaggagaa
     2281 cagacggatg cggggccttc tccaggccgc cctgcagagg aaaggcatac agtgcgccac
     2341 agctcctcaa gacacttgct tgagccgcct ctctcaggga gacctgctaa ttggccatga
     2401 tttcagctat ggtgacgtgc agcttcctgc taccagagtc tgccagagtc tgggggagtc
     2461 tgtggcatag atctcctgtc tgaggtgtct gcctcctgca ggctggtggg tgacttctct
     2521 ccccatgcgg gccaatgtga caaggaggcc catggaagcc actgagtgtc acaggcaaga
     2581 atgaaataaa cctgcccagg catca
//
