LOCUS       NM_001395607            3830 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus centrosomal protein 85 (Cep85), mRNA.
ACCESSION   NM_001395607 XM_008764155
VERSION     NM_001395607.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Chen,C., Tian,F., Lu,L., Wang,Y., Xiao,Z., Yu,C. and Yu,X.
  TITLE     Characterization of Cep85 - a new antagonist of Nek2A that is
            involved in the regulation of centrosome disjunction
  JOURNAL   J Cell Sci 128 (17), 3290-3303 (2015)
   PUBMED   26220856
  REMARK    Erratum:[J Cell Sci. 2015 Oct 15;128(20):3837. PMID: 26471995]
REFERENCE   2  (bases 1 to 3830)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jul 21, 2021 this sequence version replaced XM_008764155.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.23065.1,
                                           SRR26643287.14535.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               JAXUCZ010000005.1  151687736-151687860 c
            126-196             JAXUCZ010000005.1  151672046-151672116 c
            197-349             JAXUCZ010000005.1  151666828-151666980 c
            350-1044            JAXUCZ010000005.1  151661338-151662032 c
            1045-1178           JAXUCZ010000005.1  151658871-151659004 c
            1179-1296           JAXUCZ010000005.1  151658318-151658435 c
            1297-1482           JAXUCZ010000005.1  151656297-151656482 c
            1483-1635           JAXUCZ010000005.1  151651785-151651937 c
            1636-1790           JAXUCZ010000005.1  151651178-151651332 c
            1791-1884           JAXUCZ010000005.1  151648679-151648772 c
            1885-1935           JAXUCZ010000005.1  151647890-151647940 c
            1936-2043           JAXUCZ010000005.1  151644294-151644401 c
            2044-2272           JAXUCZ010000005.1  151642523-151642751 c
            2273-3830           JAXUCZ010000005.1  151640316-151641873 c
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3830
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /note="centrosomal protein 85"
                     /db_xref="GeneID:362622"
                     /db_xref="RGD:1311520"
     exon            1..125
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            126..196
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2433
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /note="coiled-coil domain-containing protein 21;
                     coiled-coil domain containing 21; centrosomal protein
                     85kDa; centrosomal protein of 85 kDa-like"
                     /codon_start=1
                     /product="centrosomal protein of 85 kDa"
                     /protein_id="NP_001382536.1"
                     /db_xref="GeneID:362622"
                     /db_xref="RGD:1311520"
                     /translation="MAMQEKYPSDRSPHTASPGSNVIQKGSSLGTEWQTPVISEAFRS
                     RFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGAS
                     PAKPSPTPSGPSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLSRDFMYLPSAAGENGI
                     QQSWFPAVGHEREGEMRKFDVSSMESTLNQPAMLETLYSDPHYRAHFPTPRPDTNKDA
                     YKVLPESKKAPGSGAVFERNGPHASNSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHP
                     GEQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFTPSLPTLEPAQWISILNSNE
                     HLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENT
                     FLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKG
                     RDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTE
                     LQGRVAELETMLEDTQAACREKEVQLESLRQREAQFSSARHSFQDKQSLEEASGESLK
                     VEMESQQKECDSLRKIVERQQLKLEQLHSQVQSQKQELAQEEGISQALREEAQRRETA
                     LQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSSGSPDAAQLAYELHQELASCL
                     QDLQAVCSIVTQRAQGHSPNLSLLLGIHSTPHPGTQLDLQKPDVIRRKLEEVQQLRHD
                     IEDLRTSLSDRYAQDMGENCATQ"
     exon            197..349
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            350..1044
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1178
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1296
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1482
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1635
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1790
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1884
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..1935
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2043
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2272
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..3830
                     /gene="Cep85"
                     /gene_synonym="Ccdc21; RGD1311520"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcgacttga cgggcgtgga acggccgtta gacgacctga ggagcggatt cgccgctcgt
       61 gcggacgtgg tggccgcctt cagtatccca gagtgagggg gttcgccgct cgctctcagg
      121 tccgattgtc tcaggtaacc gatggccatg caagaaaaat acccaagtga taggtctcct
      181 cacactgctt caccgggttc caatgtgatt caaaaaggca gttctctggg aaccgaatgg
      241 cagacaccag ttatctcaga ggcttttcgg agccgcttca gccgctgctc aagcatagct
      301 gacagtgggg acacagccat tggaacatca tgctcagaca ttgcagagga tttttgcagc
      361 tcaagtggca gcccttcctt ccagccaatc aaaagccaca taaccattcc aacagcccat
      421 gtgatgcctt ccactttggg ggcctctcct gccaaaccaa gccctactcc ttccgggcct
      481 tcttctgcta aactcccttt gtcaggattg actgaaggtg tggggatgac cagaaatgga
      541 gacttcggtg cggtgaagcg ttctccgggc ctctcaagag attttatgta cctccctagt
      601 gctgctggag aaaatgggat tcagcagtcc tggtttccag cagtgggcca tgaaagagag
      661 ggggagatga ggaagtttga tgtttccagt atggagtcta cccttaacca gccagccatg
      721 ctagagacat tatattcaga tccacattac cgagcccatt tccccacccc gagaccggat
      781 accaataagg atgcatacaa agtgttgccg gagtccaaga aggcaccagg cagtggtgca
      841 gtatttgagc ggaatggacc acatgctagc aacagtgggg tgctcccttt gggactccag
      901 cctgctcctg ggctttccaa gtcactatcc tctcaggttt ggcaaccaag tcccgaccct
      961 tggcatcctg gagaacaatc ctgtgaactc agtacttgtc gacagcagtt ggaattgatt
     1021 cggttacaga tggaacaaat gcagcttcaa aatggagcaa tctgtcacca tcctgctgct
     1081 ttcactccat cactgcccac cttagagcca gcacagtgga tcagcatctt gaacagtaat
     1141 gaacatctcc tgaaggagaa ggagcttctc attgacaagc agaggaaaca tatctctcag
     1201 ctggagcaga aagtgcgaga gagtgaactg caagtccaca gtgcactttt gggccgccct
     1261 gccccctttg gggatgtctg cttgttgagg ctacaggagt tgcagcgaga gaacactttc
     1321 ttacgggcac agtttgcaca gaagacagaa gccttgagca aagagaagat ggagcttgaa
     1381 aagaaactgt ctgcttcaga agttgaaatt cagctcatca gggagtctct caaagtgaca
     1441 ctgcagaagc attcggaaga ggggaagaag caggaggaaa gggttaaagg tcgtgataaa
     1501 catatcaata atttgaaaaa gaaatgtcag aaggaatcag agcagaaccg ggagaagcag
     1561 cagcggattg aaaccttgga gcgctatctc gctgacctgc ccaccctaga agaccatcag
     1621 aaacagacgg agcagcttaa ggacgctgaa ttgaagaaca cagaactgca agggagagtg
     1681 gcagagctgg agactatgct ggaggacaca caggccgcct gcagggagaa ggaggttcag
     1741 ctggaaagtc tgagacaaag agaagcgcaa ttctcctctg ctagacatag ctttcaagat
     1801 aaacagtctt tggaggaagc cagtggtgaa agcctcaaag tggaaatgga atcccagcag
     1861 aaggaatgtg attccctccg aaagatcgtg gagaggcaac agctgaagtt ggagcagctg
     1921 cactcgcagg tccagagcca aaagcaagaa ctggcacaag aagaaggaat aagccaggcg
     1981 ttgagagagg aggcccagcg gagggagaca gccctgcagc agatgcgcac agccgtgaag
     2041 gagctctcag tgcaaaatca ggacctgatt gagaagaatc tgacactgca agagcacttg
     2101 cgccaggccc agccagggtc ctcgtcaggg tccccagacg ccgcccagct ggcatatgag
     2161 ctgcaccagg aactggccag ttgccttcaa gacctgcaag ctgtctgcag cattgtgacc
     2221 cagagggccc agggccacag tcctaacctc tctctgctcc taggcattca ctccacccct
     2281 cacccaggga cacagctaga tctgcagaag ccagatgtga tcaggaggaa actggaagag
     2341 gttcagcagc ttcgccatga cattgaggac ttaaggacca gcctgtcaga cagatatgcc
     2401 caggacatgg gagaaaactg tgccacacag tgaggagtgc cagggagggc ctaggctgct
     2461 gctagccccg ccagaaggtt ccttccctga cagttctgcc ttttgctgct gcacccagag
     2521 ggagagcctg tatctggggc cagggttgtg agaagcctgc ctgttttgcc gtactctggc
     2581 tttgccttat tggcttatgt ttcgcctgtt aagtcactct taaaggccga gttactaatt
     2641 aaccgttttg cagatttcaa ctgataacgt tctcacgagt tgttcccagc tccagtctgc
     2701 catgagaagc agacaggctg cttgcctccc ttcatcctct gggatggacc cctgttcatt
     2761 cctacccatc ccttggtcct actgatgctg tagtgagaga ggcctcaagg gttaagtagg
     2821 agtagcgacc tttgagaatt ctcaggccca ttgtatcagc cttcctggga actcagctgg
     2881 cttctgggtt ctctcaggta cctgcttcct cagggctctt gttcccacag aggcctcagg
     2941 gttttgtacc ccacagcaaa gtccctactg tgcctagtgg cttgggacta gcagggctct
     3001 tgagcctgcc tgctgtgccg tcttttacag gaagctcttc ctagctgccg tttgtctgtc
     3061 cctagaaccc tgggcgtgtg ggcatgcgct tgggtcttct cttctatggc tgccctgtgg
     3121 ttcccgcata agcccacagg gcagctgtca ctgctcgctc cttcctaaga ctggggtctg
     3181 tagctgctct gaattgtgcc tctcatttgg ggtttggagg gtttcctttt cctgctctga
     3241 ccttgagcgt tcagagcacc tagtgtgggt cagcactaag gtgaaacagt cttgagtgtt
     3301 tcctggtgtt ttgtgtttct ctagagcctt tgacccttaa cttcatggtt tttcttgcct
     3361 tccgatttaa ggattgtctc ggttttatct ggttgttggg ccagccctca acctcctcta
     3421 gtttggagct aatacgggct ccatatgtat gaggagcaga atagtcgtgg gggtgcagag
     3481 gcagccatga caggacttct gctaagcctg tgggctgtta aaagcactct ggacctccag
     3541 ggcctaagtg ggcctcttta caagtgtttt aacaagttta tgttttattt atggagtggc
     3601 ttacctttca gagtagccac acccagttga ctatcccctc agcctctggg ctgctgcctc
     3661 ctagaaacag agcttcctgg ttggtctccc ccatgtcatg tggagcccag cctccatgct
     3721 cacgggtact ttcttggtaa agtttataaa gttatttata tgaatctttg ttatgttgac
     3781 tggttttatt gcctattttg attacagaat aaaacgttta acaaatgctg
//
