LOCUS       NM_001108124            2519 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus centrosomal protein 57 (Cep57), mRNA.
ACCESSION   NM_001108124 XM_001073869 XM_235823
VERSION     NM_001108124.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2519)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   2  (bases 1 to 2519)
  AUTHORS   Momotani,K., Khromov,A.S., Miyake,T., Stukenberg,P.T. and
            Somlyo,A.V.
  TITLE     Cep57, a multidomain protein with unique microtubule and
            centrosomal localization domains
  JOURNAL   Biochem J 412 (2), 265-273 (2008)
   PUBMED   18294141
REFERENCE   3  (bases 1 to 2519)
  AUTHORS   Kim,Y.S., Nakanishi,G., Oudes,A.J., Kim,K.H., Wang,H.,
            Kilpatrick,D.L. and Jetten,A.M.
  TITLE     Tsp57: a novel gene induced during a specific stage of
            spermatogenesis
  JOURNAL   Biol Reprod 70 (1), 106-113 (2004)
   PUBMED   12954732
REFERENCE   4  (bases 1 to 2519)
  AUTHORS   Andersen,J.S., Wilkinson,C.J., Mayor,T., Mortensen,P., Nigg,E.A.
            and Mann,M.
  TITLE     Proteomic characterization of the human centrosome by protein
            correlation profiling
  JOURNAL   Nature 426 (6966), 570-574 (2003)
   PUBMED   14654843
REFERENCE   5  (bases 1 to 2519)
  AUTHORS   Bossard,C., Laurell,H., Van den Berghe,L., Meunier,S.,
            Zanibellato,C. and Prats,H.
  TITLE     Translokin is an intracellular mediator of FGF-2 trafficking
  JOURNAL   Nat Cell Biol 5 (5), 433-439 (2003)
   PUBMED   12717444
REFERENCE   6  (bases 1 to 2519)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB807650.1, BC168198.1 and BI291153.1.
            
            On Oct 1, 2011 this sequence version replaced NM_001108124.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168198.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 CB807650.1         53-61
            10-2077             BC168198.1         1-2068
            2078-2519           BI291153.1         1-442               c
FEATURES             Location/Qualifiers
     source          1..2519
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q12"
     gene            1..2519
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /note="centrosomal protein 57"
                     /db_xref="GeneID:315423"
                     /db_xref="RGD:1309884"
     exon            1..198
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..1653
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /note="translokin; centrosomal protein 57kDa"
                     /codon_start=1
                     /product="centrosomal protein of 57 kDa"
                     /protein_id="NP_001101594.2"
                     /db_xref="GeneID:315423"
                     /db_xref="RGD:1309884"
                     /translation="MAAASVSAASDSQFSSVLAEPSRSNGNMVHHSSSPYVLYPPDKP
                     FLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIRAEESVKTLSRETI
                     EYKKVLDEQIQERENSKNEESKHNQELASQLVAAENKCNLLEKQLEYMRNMIKHAEME
                     RTSVLEKQVSLERERQHDQSHVQSQLEKLDLLEQEYNRLTAMQALAEKKMQELESKLH
                     EEEQERKRMQARAAELQSGIEANRLIFEDRNTSCVSTSTRKIKKKKSKPPEKKGFRNN
                     FGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSRALCNDRVVNSVPLA
                     KQACSRGSKSKKSVAPPSSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQESPSEEL
                     KDNLECELEALVRRMEAKANQITKVRKYQAQLEKQSTDKQKELKGNKKTLDEEGNSSS
                     RSSVITRTTSKKDFTKQRPGEKSRKNLQLLKDMQTLQNSLQSSNVCWDY"
     exon            199..355
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            356..535
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            536..657
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            658..774
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            775..852
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            853..963
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1041
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1277
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1422
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..2503
                     /gene="Cep57"
                     /gene_synonym="3110002l15rik; RGD1309884"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atccttgtgg tttgtgagac cgaggctcct ataaggttca cagctcgccc gccctttcca
       61 tcggggactt ggattcggct tgccccaggc gtgcggctgt cgaatccggg ggaggggctc
      121 caggacggcg gcccgcgttg cgcaggtggg aagatggcgg cggcctcggt ctcggcggct
      181 tctgattctc agttttcgag cgtcctagct gaaccatcaa ggtctaatgg aaatatggtt
      241 catcattctt catcaccata tgtattgtat ccacctgata agcctttcct taacagcgat
      301 ctgagacgct ccccaaataa gcccacgttt gcctatccgg aaagcaacag cagagccata
      361 ttttctgctc ttaagaatct tcaagataag attcgacgcc tggaactgga aagaattcgg
      421 gcagaagaaa gtgtgaaaac cttgtctagg gagacaattg agtataagaa agtattggat
      481 gaacagatac aagagaggga gaactcaaag aatgaagaat caaagcacaa tcaagaactg
      541 gcatctcagt tggtagctgc agaaaataaa tgtaatcttt tagaaaaaca attggaatac
      601 atgcgaaata tgataaagca tgcagaaatg gagagaacat ctgtcttaga aaagcaggtt
      661 tcgctagaaa gagaacggca gcatgatcaa agccatgttc agagccagct ggaaaaactg
      721 gatcttcttg aacaggaata taacagactc accgcaatgc aggcccttgc agaaaaaaaa
      781 atgcaagagt tggagtccaa actccatgaa gaagagcagg aaaggaagcg tatgcaggct
      841 cgggcagcgg agttacagag tggtatagaa gcgaacagac ttatatttga agatagaaat
      901 acttcatgtg tttcaaccag cactagaaaa ataaagaaaa agaagtcaaa accaccagaa
      961 aagaaaggtt ttaggaacaa ctttggtgca cagccacatt acagattgtg cttaggtgat
     1021 atgccttttg ttgctggaac gtccaccagt cccagccatg ccgtggtagc caatgttcag
     1081 cacgtcttgc atctgatgaa gcatcacagc agagccctgt gcaatgaccg ggttgttaac
     1141 agtgtgccct tggcaaagca agcttgttca cgaggtagta agagtaagaa gtcagtggcg
     1201 cctccctcca gcagtgttaa cgaagaactt tcggatgtct tacagacgtt acaggatgaa
     1261 tttgggcaaa tgagctttga ccaccagcag cttactaaac tcatacagga atcacccagt
     1321 gaggagctga aagacaacct ggagtgtgaa ctggaggcat tagtgagaag aatggaagcg
     1381 aaggccaacc agataactaa agttcgaaag taccaagccc agctggagaa acaaagcaca
     1441 gataagcaga aggaactaaa aggtaacaag aagactcttg atgaagaagg aaacagcagc
     1501 agtcgttcat ctgtaatcac aaggaccaca agtaagaagg attttaccaa acagagacct
     1561 ggagaaaaaa gcaggaaaaa tcttcagtta ctgaaggaca tgcaaacctt acagaattca
     1621 ttacagagta gtaatgtgtg ttgggattac tgacaccagg tcatatgatg taccttactg
     1681 gtcataaaca atgtacttac tggaccatga gcagactttc caggtctcgt gcttgctaag
     1741 ctgccattac tggccggtgt tagggccagg cttcattaca gtgtgatgtg ctgtgcagca
     1801 caactaaatg gacatggagt tctgcagcag agaagccgca ttgtgtcttt gaacttgctg
     1861 gattcaaaca ctgcactttg taaacaaatg accagttttt tacttgtggg tgtgtttttt
     1921 aagtaggtat atatgtaaat tgggtttgaa aattcagaat atgagggtgt ccccatagtc
     1981 agtgcttgaa gtcttatttt taaatctccc cagagcatga agtgcccact actttccctt
     2041 ctccagatga ccattaaatg tactgttttc aagaggactt tgttttgctt tggtatttca
     2101 gacattgatc aatagtaaat ttactattaa agacccaaac attttaagtc agttccccat
     2161 gaaatatgtt acaatgtctt cataaaactc taaacagttg ttaatgaagt aaatgaaatt
     2221 ttggaataaa gaatgagaat ggggggtgtt ggaaaatgta cgcatttgca ggttttagac
     2281 agtacctgtt tgtaatcatg ttatgctaag cactgtttaa tttgactctt agagaacccc
     2341 atgctttttc catacagtat gagggtagta tgtgaactga atacacacat ctatcatgtc
     2401 aatgtgaatt attaattttg aatagatcga catgttaatc tttatgaatt tggtacttca
     2461 agtcaataaa gcaattttta aactttgctt aacagccacc taaaaaaaaa aaaaaaaaa
//
