LOCUS       NM_001415927            3496 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus centrosomal protein 41 (Cep41), transcript
            variant 2, mRNA.
ACCESSION   NM_001415927 XM_006236229
VERSION     NM_001415927.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3496)
  AUTHORS   Ishikawa,H., Thompson,J., Yates,J.R. 3rd and Marshall,W.F.
  TITLE     Proteomic analysis of mammalian primary cilia
  JOURNAL   Curr Biol 22 (5), 414-419 (2012)
   PUBMED   22326026
REFERENCE   2  (bases 1 to 3496)
  AUTHORS   Lee,J.E., Silhavy,J.L., Zaki,M.S., Schroth,J., Bielas,S.L.,
            Marsh,S.E., Olvera,J., Brancati,F., Iannicelli,M., Ikegami,K.,
            Schlossman,A.M., Merriman,B., Attie-Bitach,T., Logan,C.V.,
            Glass,I.A., Cluckey,A., Louie,C.M., Lee,J.H., Raynes,H.R.,
            Rapin,I., Castroviejo,I.P., Setou,M., Barbot,C., Boltshauser,E.,
            Nelson,S.F., Hildebrandt,F., Johnson,C.A., Doherty,D.A.,
            Valente,E.M. and Gleeson,J.G.
  TITLE     CEP41 is mutated in Joubert syndrome and is required for tubulin
            glutamylation at the cilium
  JOURNAL   Nat Genet 44 (2), 193-199 (2012)
   PUBMED   22246503
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3496)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 3496)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 3496)
  AUTHORS   Andersen,J.S., Wilkinson,C.J., Mayor,T., Mortensen,P., Nigg,E.A.
            and Mann,M.
  TITLE     Proteomic characterization of the human centrosome by protein
            correlation profiling
  JOURNAL   Nature 426 (6966), 570-574 (2003)
   PUBMED   14654843
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 5, 2023 this sequence version replaced XM_006236229.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.22336.1,
                                           SRR26643295.17844.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                JAXUCZ010000004.1  60277935-60278022   c
            89-152              JAXUCZ010000004.1  60264966-60265029   c
            153-200             JAXUCZ010000004.1  60256377-60256424   c
            201-262             JAXUCZ010000004.1  60252303-60252364   c
            263-332             JAXUCZ010000004.1  60251192-60251261   c
            333-477             JAXUCZ010000004.1  60245991-60246135   c
            478-629             JAXUCZ010000004.1  60244056-60244207   c
            630-697             JAXUCZ010000004.1  60243564-60243631   c
            698-812             JAXUCZ010000004.1  60242451-60242565   c
            813-1028            JAXUCZ010000004.1  60241692-60241907   c
            1029-3496           JAXUCZ010000004.1  60238602-60241069   c
FEATURES             Location/Qualifiers
     source          1..3496
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..3496
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /note="centrosomal protein 41"
                     /db_xref="GeneID:500069"
                     /db_xref="RGD:1562034"
     exon            1..88
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1177
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /note="isoform 2 is encoded by transcript variant 2;
                     centrosomal protein of 41 kDa; testis specific gene A14;
                     testis specific, 14; testis-specific gene A14 protein;
                     centrosomal protein 41kDa"
                     /codon_start=1
                     /product="centrosomal protein of 41 kDa isoform 2"
                     /protein_id="NP_001402856.1"
                     /db_xref="GeneID:500069"
                     /db_xref="RGD:1562034"
                     /translation="MSARRHIGNPEYLTRRIPQNPRYQHVKSRLDTGNSMTKYIEKLE
                     EIKKNYRYKKDELFKRIKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDSDSATSEAD
                     TDIAAKTNGKGSPEEQSPSPVQFINSTGAGDASRSTLQSVISGVGELDVDKGLVKKEE
                     PSGKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAH
                     GKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQ
                     ALPFGSVRKRPGPKMPALPAENKWRFTPEDLKKIECYLEADQGPANNPSRLNQNNSAG
                     RDLKVPAGRGGQNLPTGCPTSHSNSRTLNSGHLQGKPWK"
     exon            89..152
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            153..200
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            201..262
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            263..332
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            333..477
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            478..629
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            630..697
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            698..812
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            813..1028
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..3496
                     /gene="Cep41"
                     /gene_synonym="Tsga14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agattagtgg caagacgtga ggctagaacc ccgagcgtgg tcggttggag caaatatgtc
       61 tgcccggagg cacattggga atcctgagta tctgaccaga cggataccac agaacccaag
      121 gtatcaacat gtcaagtcaa gactggatac tggaaacagc atgaccaaat acattgagaa
      181 gctagaagag attaaaaaaa attatagata caaaaaagat gaacttttca agagaataaa
      241 agttaccact tttgcccagc tggtcattca agttgcttcc ctgtcagatc aaacactgga
      301 agtgacagct gaggagatcc aaagactcga agacagtgat tctgcaacgt cagaggctga
      361 cactgacatt gctgccaaga ccaatgggaa agggagccct gaggaacagt cgcccagccc
      421 tgtccagttc atcaacagca cgggagcagg ggacgccagc cgctccactc tgcagagcgt
      481 catcagtggc gttggggaac tggatgtaga caaagggctc gtaaagaaag aagagcccag
      541 tggcaaagac aagccttatc ccgactgtcc cttcctgctg ctagatgtgc gtgacagaga
      601 ttcttatcag cagtgtcaca ttgtcggggc ctacagttac cccattgcaa ctctatccag
      661 gacaatgaac ccctattcaa acgatattct tgagtataaa aatgctcatg gcaagatcat
      721 catcttgtac gatgacgacg agaggctagc cagccaggca gccaccacca tgtgcgagcg
      781 cgggtttgaa aacctcttca tgctttccgg gggtctgaaa gtcttagctc agaagtttcc
      841 ggaaggactg gtcactggtt ccctgccagc ctcttgccaa caggcccttc cttttggttc
      901 tgtccggaaa cgacctggcc ccaaaatgcc agccctgcca gctgagaaca agtggagatt
      961 taccccagaa gacttaaaaa agatagaatg ttacctggaa gcggaccagg gaccagccaa
     1021 caaccctagc cgactgaacc agaataactc tgctggaaga gacttgaagg tgcctgccgg
     1081 ccggggtggc caaaacctgc ccaccggctg tcctaccagc cactcgaact cccgaacact
     1141 caacagtggt cacctgcaag gcaaaccctg gaagtgaagg cctgtgttgt ttagtcaaat
     1201 aaatgtcccc tccttttgga acccccaaca ctcccaactt ggtccttttc agaactgctg
     1261 tagggaaaca gccatgctac tcgggctgga ccaggcccac ttctcactgt cttagctccc
     1321 ttcccttcat tcaggaagga ttttgacagc tgaccacgaa agccagaggc ttgacaggca
     1381 ggctctagtt gctttcccta tttgtttaca caagattcat gtcttttgaa actgaatagg
     1441 aaaaaagaaa gatactttct tttaaataag gtccagcctg tttggtctgt aaccagtgtt
     1501 gttctttaaa taattcagtc acatctgctg ctgtgttctt cccagccagc ttttttcatt
     1561 cactgttgat ttctgaaaaa ttctccaggt gggcctggcc ttggccactg tccccagggg
     1621 cacagatgag ttcttggttc ctgcagccca caggccccac actgggccag gtggctggct
     1681 gagtcttagc tctctatgtg ctggcgctgc aggctctacg tgctgcaggc tctacgtgct
     1741 gcaggctcta cgtgctgcag gctctatgtg ctgcaggctc tgctgggcac ttgaagctga
     1801 ggggtgatcc gtgagcatgg gtccatctta ctggtttagc agaaaaactc tctgcaaaat
     1861 gatcccctcc ttaaatggtt tcccgggacc agaaagctgt gtgctcagct gtcctcacca
     1921 gaagacccca gtattctaca ggtctatgct gagaaccctg cccgggaggc cgctgcagct
     1981 gtccccttca ttatgagcct tatatcaatt aaaatttccc attgcctgat ttgagtcccg
     2041 cgatagtaga tggatagaaa tcacggtcat ttgaaagctt cactttgaca aggggacaca
     2101 caggtgagga ggactcgtga gtcctttgtc agggctgaca accccttaag cccttgctta
     2161 aaatacagta ttagtctaat tgagtaatta gtgcaatttc ctgcttgctt ttcattctca
     2221 cgactgagct gtgattagaa gtctgtgatt atagattctg gttttggccg gaatttcgaa
     2281 tcggcattaa ttgaattgct agatgactga catccattct atttaattgg gggaacaaaa
     2341 gacctcaggt aaggatgagg cccatgaagt cataggcaag gacgagcctt gttcattttt
     2401 atggtctgtg atcgtagctc tgataaggga ctgaagaata aattgtgcgc tttgtcatgg
     2461 caaccagctt ctgaaaagcc agctgaaaat tgcctatcct taggtagtta ttgctggtgg
     2521 gtaagattcg ccttagcagt acgatttctt caccacttta aaaaaaaaaa aaaaggaaaa
     2581 ggcttacagt atttctagca ctgaggctgt gtttgtaaga gaaataaatg taataaatat
     2641 ctcatggaga catatggaaa aataactcgg tcaacccagc cctggttcag aatgtgttta
     2701 ttcttctctc cttgatttcc aaagtgcaac attttccaat gctttagaaa tcaaacaaac
     2761 cagggacatt gttcagatgt caagccgtgc ccaaatttcc acaagattcg agaatcgtgt
     2821 ataaaattca gccaacgtac acatagcttt aatgaggagc ctgtcgtgtt tccccataga
     2881 tttattgcct gagaacttag ttcagccttt ttctaatgcc aaaatgcact ggctttttat
     2941 tttctttaca gcatagatag aaaaatgcaa atttttccac actcagcttt cccctagcat
     3001 ggagaagatt ttcagtcatc tttgacatat atacattttt aaggaaaatg cttttcctca
     3061 gtaagaaagt tctggtttgc cagtttaaca tcagctagtc aggaggtaga cctcttcacc
     3121 caattttgtt tcgaaagtct ctatcggttc ctgttctgca ttcctgcact gggtgttagt
     3181 gttagaaatg attgtatata cgtcgcagag tctgttccag cgaagctgtt agagtcgctg
     3241 tgtatttact ggtgtggtct agcaggctga atctattccc atgtgtttct ccatagctct
     3301 ttgccccgtt ggcaaggatt tcaaacttcc aagagagctg gtcccctctg cactcagtgt
     3361 tactctccga cgcggttgct tctcagcact gggctttacc agtttcttcc ttagattgtt
     3421 tcacatgtat tatttaaatg atcagtgata ctttgtgcaa ttatgaatgt tgaagattaa
     3481 agaacgtagt tactaa
//
