LOCUS       NM_001271048            7309 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus centrosomal protein 295 (Cep295), mRNA.
ACCESSION   NM_001271048 XM_001069542 XM_343351
VERSION     NM_001271048.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7309)
  AUTHORS   Chang,C.W., Hsu,W.B., Tsai,J.J., Tang,C.J. and Tang,T.K.
  TITLE     CEP295 interacts with microtubules and is required for centriole
            elongation
  JOURNAL   J Cell Sci 129 (13), 2501-2513 (2016)
   PUBMED   27185865
REFERENCE   2  (bases 1 to 7309)
  AUTHORS   Izquierdo,D., Wang,W.J., Uryu,K. and Tsou,M.F.
  TITLE     Stabilization of cartwheel-less centrioles for duplication requires
            CEP295-mediated centriole-to-centrosome conversion
  JOURNAL   Cell Rep 8 (4), 957-965 (2014)
   PUBMED   25131205
REFERENCE   3  (bases 1 to 7309)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 7309)
  AUTHORS   Knorz,V.J., Spalluto,C., Lessard,M., Purvis,T.L., Adigun,F.F.,
            Collin,G.B., Hanley,N.A., Wilson,D.I. and Hearn,T.
  TITLE     Centriolar association of ALMS1 and likely centrosomal functions of
            the ALMS motif-containing proteins C10orf90 and KIAA1731
  JOURNAL   Mol Biol Cell 21 (21), 3617-3629 (2010)
   PUBMED   20844083
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CB704880.1,
            JAXUCZ010000008.1, CO382359.1, BF397648.1 and BM386844.1.
            
            [WARNING] On Oct 10, 2024 this sequence was replaced by
            NM_001271048.3.
            
            On Oct 7, 2014 this sequence version replaced NM_001271048.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-348               CB704880.1         1-348
            349-450             JAXUCZ010000008.1  20471465-20471566   c
            451-575             JAXUCZ010000008.1  20470243-20470367   c
            576-669             JAXUCZ010000008.1  20469315-20469408   c
            670-765             JAXUCZ010000008.1  20464840-20464935   c
            766-906             JAXUCZ010000008.1  20461743-20461883   c
            907-1090            JAXUCZ010000008.1  20459094-20459277   c
            1091-1198           JAXUCZ010000008.1  20458752-20458859   c
            1199-1423           JAXUCZ010000008.1  20456034-20456258   c
            1424-1516           JAXUCZ010000008.1  20454330-20454422   c
            1517-1620           JAXUCZ010000008.1  20454090-20454193   c
            1621-1755           JAXUCZ010000008.1  20453416-20453550   c
            1756-1853           JAXUCZ010000008.1  20453138-20453235   c
            1854-5202           JAXUCZ010000008.1  20449526-20452874   c
            5203-5362           JAXUCZ010000008.1  20448229-20448388   c
            5363-5506           JAXUCZ010000008.1  20447968-20448111   c
            5507-5659           JAXUCZ010000008.1  20447088-20447240   c
            5660-5778           JAXUCZ010000008.1  20444865-20444983   c
            5779-5881           JAXUCZ010000008.1  20444253-20444355   c
            5882-6024           JAXUCZ010000008.1  20442297-20442439   c
            6025-6169           JAXUCZ010000008.1  20441755-20441899   c
            6170-6240           JAXUCZ010000008.1  20441174-20441244   c
            6241-6960           CO382359.1         1-720
            6961-7292           BF397648.1         27-358              c
            7293-7309           BM386844.1         22-38               c
FEATURES             Location/Qualifiers
     source          1..7309
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q12"
     gene            1..7309
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /note="centrosomal protein 295"
                     /db_xref="GeneID:363018"
                     /db_xref="RGD:1311723"
     CDS             1..7173
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /note="KIAA1731-like protein"
                     /codon_start=1
                     /product="centrosomal protein of 295 kDa"
                     /protein_id="NP_001257977.2"
                     /db_xref="GeneID:363018"
                     /db_xref="RGD:1311723"
                     /translation="MTEVTRSGPWLSSRYPNGCWVTGRVQIPVCCEVRPHTLSDPLYL
                     KYSEMKRKVMNGKLRLSPNEEAFILKEDYERRRKLRLLQVREQERGIAFQIREDIKQR
                     RNQQVSHLAEELRAEWEEAQSQKIQNLEKLYLASLRHMGDGHQQAKENEPDLDALSRR
                     AAERKTKAEARHKEALKAQKKQKEMLMKQKTRHIKARKEAVLVEKERSAKMARLPPPV
                     PSPFENIDINRIPSLKTNRSTYHHISAFVSRQMGTKQPDAHLAAEEEARRVERLRKQA
                     AQERMEQSERAHARGSQAMKKIHLAQNQERLMEELKQLQREDLACKRQTAAQMPSQLL
                     ELPYRRSEMKEDWQRELEFAFEDVYSADRKVKGNLILHLKPEPLPTMSDQLQDEELDL
                     SMEQENEVPLATKTQQIPSRILLKRLLNKIRNQKSLWTIKSFSEDDNQVTASIISEIE
                     RKVPSTDSGTITTGETAVSFEQEQVMGSDRLMIESGPPSSEDKPLCYKSVTGKEQAMG
                     VSPPATTVAQSSVLLHPQEEAARLRMSARHKQIMEIEEQKQKQLELLEQIEQQKLRLE
                     TDCFQAQLEETRKQADHLEVRPAPVSHAMISDEERHRQMIRNYQYQLLQQNRLHKQTV
                     ETARKRLLEYQTVLKERCPSMSARSLIPDSVVSEPPQQAQKPAVASDYWDPSQRPKLS
                     PSKYQPVQPSQIPALDQNHIQVPRQGHIPQRQGETARAKQSVESQERQWQFSQVETQQ
                     RDYEFIFKDSHSLSRTSSYVRPQTLQAAGEVSKPLRAIICQTSDSQQISSEDSENISS
                     KPTEPSSSLPLMPECSSSSLSVKLESETIQKAFTTVNRSVISQMHGQPLSSSETGTTQ
                     QGDIRFLQGQLELQKKVLQERQEAQEKLLSCTQKELEEQTGIPVFFPSPVGNMFSSLP
                     SASAESGNIQTSSTKSDATVSSDSMDNPYSQPISLRQTNLEFLQEQFSVEKDNLQARR
                     EAQEVSFTHTQSKLDKIVRSEQTGSSWPQLVALESFSSLTSADTQSRKIQKPPLPTNK
                     KGLLPSQSEILSSQDGSSGFLQQTLPLQNTLKLLQEQLTIQRGMIQPRLNAQETLLLH
                     KERCSVDSKAGPVNSLSSAVAQHSEAGPQSLQELYSSKKENTVLSSHLITPEVQEESH
                     GSPQHSLPRQEHFASLQEQAHIQRVILGARKQIQEFAHKQNEFKKGLYSQQTGALSSP
                     SQGTGWEISQESLSVRSDSTDPLSHFKIPGFQERLVRALQPTFPLRDNLQEHQEWVDP
                     EKESFQFSPQTQENRSSQQTGFSSFTPSLRQPSCVSLPSVDSGITQHPLSTERDSKVT
                     SSHLQIPELQHRLLKISQLIQPQQDSLKALQEQLATSRTIIHSRQEALEETLREWKEK
                     IFPEQVGPFSPLMTQHSFASFPVSDIERAQELCSTNSEGAISSGYSEMLELPDRALGL
                     SCTALPQQGNLTVHPGHLHAQTNSFHSTEKAQEKLVFPRPCKLEEISAEHSIQPPHDD
                     LQALQQQLDVHREAIRSCQDIQEELLLQRLNKLEQRVSSKQISSSPLLSQVALPIANS
                     EGTLQSSPAKNDDTEMLRSHSEYLNFSQPLQDNVTEQLDLEVVFHKELLLHKQKSQTK
                     SESPEHSLPALFLPKEIEHPFIPLPFAETKSKSICESYLSEKEHAAPFNDAVIPRLQD
                     RLLSYFQPALTQQDSMSPQKQLNLQREALYSRQKAQEELLVQRQTALQQQVQKHRETL
                     KGFSNVSQTRAASGENDLEMQKTEQLTGWFPHIQGWPWGDSSQGSSSGDQPGAAAVHA
                     EHSGESLGKELSGRASKPPVSKVKCVFDLNQHELSTIQEVESPTSGRTSMPGKAEFYR
                     DRDPLRVSVSREQSYLGSPVAHDPFGCHQPSVQENSKSHDTAKAVKVKKSDIEDHALL
                     SHAISEEEEEEEACTNLSPLMKPDDEVETQEISQELLSSMTVSTGSFLSYEITDLSLT
                     DPVPAVDLDFPELEHLFPHLHRQLFKPLEPHLDLDLSSPGTSQEDRDFYQNSESSSEK
                     HVKALSTSTLCFTALTAGSHSPNSRLNQQLDVNLAHATTEGSEQSFQQLLPEFSSQES
                     QHTDLPSIYSIEARGTSQSMENQNYSEILQNKKKSIYFQPSTENLSPACSSSDTTLFD
                     QLHPQHSTPCGSVSSEGSVKQLEGREEMLGFEELSRRAVPMSQRLTEDENVVLPINPY
                     VGTVEMETSIQGSNSLSIQNEKPIQNVIKTETTKAVRNVCQLAQEEHMLKSESCPFRR
                     PIPVWETETGYGIMEEPDLTLLSTSDISITDTDLANLTIEDNEAQCSQAGAVQPSSSV
                     ETTFCGAASEPWADQPTVASSAIPGSLGEAFMKRKKTFMERSYQRQREIWNKTPLPQA
                     KVSKEKLSTKAVSGDETAKRNRSQCI"
     exon            1..118
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            119..249
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            250..450
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            451..575
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            576..669
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            670..765
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            766..906
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1090
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1198
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1423
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1516
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1620
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1755
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1756..1853
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..5202
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5203..5362
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5363..5506
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5507..5659
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5660..5778
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5779..5881
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            5882..6024
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            6025..6169
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            6170..6759
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            6760..6888
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            6889..6982
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            6983..7120
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
     exon            7121..7309
                     /gene="Cep295"
                     /gene_synonym="RGD1311723"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgacggaag taacgagatc ggggccatgg ctgtccagca ggtacccaaa cggctgctgg
       61 gtaactggca gggtgcagat tcctgtgtgc tgtgaggtcc gaccacacac gctgtcagat
      121 cctttatatt taaaatactc agaaatgaaa agaaaggtaa tgaatgggaa gctgagattg
      181 agtccaaatg aagaagcctt cattttgaag gaagattatg aacgaagacg gaaactaaga
      241 ttgctacagg ttcgagaaca agaaaggggc attgccttcc agataagaga agacataaaa
      301 cagaggcgaa accagcaggt ttctcatttg gctgaggagc taagggcaga atgggaagaa
      361 gcacaaagcc agaaaataca gaacttggaa aaactgtatt tggcaagttt aagacatatg
      421 ggagatggac atcaacaggc taaagaaaat gaacctgact tggatgctct ttctcggcgg
      481 gcagcagaaa gaaaaacaaa agcagaagcg aggcataaag aagccctaaa agcacagaaa
      541 aaacaaaaag aaatgttaat gaaacagaaa accaggcaca taaaagctcg aaaggaagca
      601 gtgcttgtgg aaaaagagag atctgctaaa atggccaggc tgccaccacc tgtcccgtcc
      661 ccctttgaga acattgacat aaacagaatt ccttcattga aaaccaaccg ttccacctac
      721 catcatattt ctgcctttgt gagtagacag atgggtacaa agcagccaga tgctcatttg
      781 gctgctgaag aagaagctag acgggtggaa agactacgaa aacaggcagc acaggagaga
      841 atggagcagt ctgaaagggc acatgcacga ggatcccaag ccatgaaaaa gatccacttg
      901 gcccaaaacc aggagcgatt gatggaagaa ctcaaacagc tgcagagaga ggacctggcc
      961 tgtaagaggc agacggcggc tcagatgccg tcacagctgc tggagctgcc atacagacgg
     1021 agtgagatga aggaggactg gcagcgggag ctggagtttg ccttcgaaga tgtgtacagt
     1081 gcagacagga aggtgaaagg aaacctgatt ttgcatctta agccagaacc attgcccaca
     1141 atgtctgatc agctccaaga tgaagaactg gacctttcaa tggaacaaga aaatgaagtg
     1201 cccttggcaa caaagaccca acagatccct tcaagaattc ttttgaaaag attattaaac
     1261 aagattcgaa atcaaaaatc tctctggaca attaaatcct tttcagagga tgacaatcag
     1321 gtgactgcta gcatcatcag tgagattgag agaaaagtac ccagcacgga ctcaggaacc
     1381 attaccacgg gggagacagc agtgtccttt gagcaggagc aagtcatggg cagtgatagg
     1441 ctgatgatag aatctggacc accgagtagt gaagacaagc cactttgcta caaatcagtt
     1501 accggaaagg aacaagcgat gggtgtgtct ccacctgcca caactgtggc tcagagttca
     1561 gtcctgcttc atcctcagga agaagcagcg agacttcgaa tgtcagcaag gcacaaacag
     1621 ataatggaga tagaagagca gaagcagaag cagttggaat tacttgaaca aattgagcaa
     1681 cagaagttaa ggttagaaac tgactgtttc caggctcaac tggaagagac aagaaagcaa
     1741 gctgatcatc ttgaggttcg ccctgctcca gtgtcacatg ctatgatttc tgatgaagaa
     1801 cgtcacaggc agatgattcg taactatcaa tatcagcttc tgcaacagaa caggttacat
     1861 aagcagactg ttgaaactgc caggaaacga ttactcgaat accaaactgt attaaaagaa
     1921 agatgcccat ccatgtcagc cagatcactg atacctgatt ctgttgtatc agagccacct
     1981 caacaagccc aaaagcctgc tgttgcctca gactattggg atccaagcca gagaccaaag
     2041 ctaagtccta gcaaatatca gcctgtgcaa ccctcacaga tccctgcatt agatcagaat
     2101 catattcagg ttccaagaca aggtcacatt ccacaaaggc aaggagaaac agctagagcc
     2161 aagcagtccg tggagtcaca ggaacgtcag tggcaattct ctcaggtgga aacacagcag
     2221 agagactatg agttcatttt taaagattct cattcacttt caaggacttc gtcttatgtt
     2281 aggccacaaa cgttacaggc tgctggagaa gtatctaaac cactgagggc aataatttgt
     2341 caaacttcag attcccaaca gatatcatca gaagatagtg aaaatatatc ttcaaagccg
     2401 actgaaccgt cttcttctct cccactgatg cccgaatgct cttccagtag tctctcagtt
     2461 aaactggaat ctgaaacaat tcaaaaagcc tttaccaccg taaaccggtc tgtaatcagt
     2521 caaatgcatg gtcagccctt gtcatcctca gagactggca caacccagca gggtgacata
     2581 aggtttcttc aaggacagtt agaactacag aaaaaagttc ttcaggaaag acaagaggct
     2641 caggaaaagc tgctttcatg cacacagaaa gaactggaag agcagactgg tatcccagta
     2701 ttcttccctt caccagttgg aaatatgttt tcttcactgc cctctgcctc agctgaatca
     2761 ggaaacatcc agacatcttc aacaaaaagt gatgctactg tttcctcaga cagtatggac
     2821 aacccatatt cacaacccat ctcattacgg caaactaatt tagaatttct ccaagagcag
     2881 ttcagtgttg agaaggataa ccttcaggct aggcgggaag cccaggaggt ctcgtttaca
     2941 catacacaga gtaagctgga taaaattgta cgttctgaac agactggatc ttcttggcca
     3001 caactggtgg ctctggagtc atttagttca ctaacatcag ctgatacaca atctagaaaa
     3061 atccagaaac cacctttacc tacaaacaag aaagggctac tcccaagcca gtctgaaatc
     3121 ttaagctctc aggatggatc ttcaggtttt ctacagcaga ccctacctct ccagaatact
     3181 ttaaaattgc ttcaagaaca gctgactata cagaggggta tgattcagcc tagacttaat
     3241 gctcaagaga cgttactttt acataaagaa agatgctcag tagacagtaa agctgggcca
     3301 gtaaactccc tctcctctgc agttgctcag cattcagaag ctgggcctca gagtctccag
     3361 gaactgtatt catctaagaa agaaaataca gttctctcca gtcatttgat caccccagag
     3421 gttcaagagg agtctcatgg ctctccacag cacagcctgc caagacaaga acattttgca
     3481 tcactgcagg aacaggcaca tattcagagg gttatacttg gtgctagaaa acaaattcag
     3541 gaatttgctc acaaacaaaa tgaatttaaa aagggactct attctcaaca gactggcgcc
     3601 ttgtcttctc catcccaagg aactggatgg gaaatatccc aggagtctct atcagtcaga
     3661 agtgatagta cagatccctt aagccatttt aagattccag gatttcagga acgactagtt
     3721 agggccttac aacctacatt ccctctacga gataatttgc aggagcacca agaatgggta
     3781 gacccagaaa aagagagctt tcaatttagt cctcaaactc aggaaaatcg atcttctcaa
     3841 cagacaggct tttcgtcctt cacaccctca ttaagacaac catcgtgtgt gtccttgcca
     3901 tctgttgact ctggtataac acagcatcct ctctcaacag agagggacag taaagtaaca
     3961 tcaagccatc ttcagatacc agaacttcag catagacttt tgaagatatc ccagcttatc
     4021 cagcctcagc aagacagttt gaaggccctt caagaacaat tagctacatc tagaacaatc
     4081 atccactcta gacaagaagc tcttgaagaa acactaagag aatggaagga aaaaatattc
     4141 ccagagcagg ttggtccatt ttctccactg atgacacagc attcatttgc ttcattccct
     4201 gtttctgaca ttgaaagagc acaagaactg tgttcaacca acagtgaagg tgccatatct
     4261 tcaggttatt ctgagatgct ggagttgcct gatagggcat tgggtttatc gtgtactgct
     4321 ctacctcagc agggtaatct gactgtacat ccaggacacc ttcatgcaca aacaaattcc
     4381 tttcattcta ctgaaaaagc ccaagaaaaa ttggtgtttc ccagaccctg taaacttgaa
     4441 gagatatctg ctgagcattc catccagcct cctcatgacg acttacaggc acttcaacag
     4501 cagttagatg tgcacaggga agccattaga tcctgccagg acatacaaga ggaactgctt
     4561 ttgcaaaggt taaataaatt ggagcaaagg gtatcttcca aacagattag ttcttctcca
     4621 ttgttgtccc aggtagcact gcccattgcc aattctgaag ggaccttaca gtcttcccca
     4681 gccaaaaacg atgatactga gatgcttagg tcccacagtg agtatctgaa cttttcacag
     4741 cctctgcagg ataatgtgac agagcagttg gacttagaag tggtatttca taaagaactg
     4801 ctattacaca aacaaaagag ccaaaccaaa agtgaatctc ctgagcattc cctccctgct
     4861 ttgtttctgc ctaaggaaat agaacatcca ttcattccat taccttttgc agaaactaaa
     4921 tcgaaaagca tttgtgaatc gtatttatct gaaaaggagc atgcagctcc ttttaatgat
     4981 gctgtgatcc caagattgca ggacagactt ttaagttatt tccagcctgc cttaactcag
     5041 caagatagca tgagtcctca gaagcagctg aatcttcaaa gagaagcttt gtactctagg
     5101 caaaaggccc aggaagaatt gcttgtgcag agacagacag ccttacagca gcaagtccag
     5161 aaacacagag agactctgaa aggtttctct aatgtcagtc agacaagggc tgcctcaggt
     5221 gaaaatgact tggaaatgca gaagacagaa cagctcacag ggtggtttcc tcacatccaa
     5281 ggctggcctt ggggagactc aagtcagggg agctctagtg gtgaccagcc aggtgcagca
     5341 gctgtccatg ctgagcacag tggtgagagt ctgggcaaag aactgagtgg aagagcctca
     5401 aagccacctg tctccaaagt gaaatgtgtt tttgacttaa accagcatga gcttagtact
     5461 atacaggaag tagagtcacc aacaagtggc aggacttcca tgccaggaaa agcagagttt
     5521 tatcgagacc gagacccatt aagggtctca gtaagcagag aacaaagtta cctggggagc
     5581 ccagtggcac atgacccatt cggttgtcac caaccatccg tccaagagaa cagcaaaagc
     5641 catgacactg ctaaagcagt taaagtcaag aaatctgata ttgaggatca tgcactattg
     5701 agtcatgcta tctcagaaga agaggaggaa gaggaagcgt gtacaaatct cagtccactt
     5761 atgaagccag acgatgaggt tgaaacacaa gagatttctc aggagctatt atcttcaatg
     5821 actgtttcta ctggaagctt cttaagttat gaaatcacag atttgagcct cacagatcca
     5881 gttccagctg tggaccttga ctttcccgaa ttggaacacc tatttccaca cttgcatcgt
     5941 cagctcttta aacccttaga accacatcta gatcttgacc tatcatcccc tgggacttct
     6001 caagaagaca gagactttta ccagaactca gaatcttcat ctgaaaaaca cgttaaggcg
     6061 ttgtccacaa gtacactctg tttcacagcg ctgacagctg gctcgcattc tcctaactca
     6121 agactgaacc agcaactgga cgttaacctg gctcatgcta caactgaggg atctgaacaa
     6181 tcttttcaac agcttctacc agaattctct tcacaggaaa gccaacatac tgatctacca
     6241 agtatttaca gcattgaagc aagaggtact tcccaaagca tggaaaatca gaactattct
     6301 gaaatactac aaaataagaa aaaaagtatc tatttccagc cctcgacaga gaatttgagt
     6361 ccagcctgca gttcatctga tactactcta tttgatcagt tacacccgca gcacagcact
     6421 ccatgtggtt ctgtctccag tgagggctca gtcaaacaat tagaaggcag agaagaaatg
     6481 ctgggttttg aagaactgtc aagaagagca gttccaatgt cacagagact cactgaagat
     6541 gaaaatgtag ttttacctat aaacccatat gtaggaacag tggagatgga aacttcaatt
     6601 caggggtcta attcattgag tattcaaaat gaaaagccca ttcagaatgt aattaaaact
     6661 gaaactacaa aagctgtaag aaatgtatgt cagctagcac aagaagaaca catgttgaaa
     6721 tctgagtcct gtccattccg gagacctatt ccagtgtggg aaacagaaac tggttatggc
     6781 ataatggaag aaccagatct cactctattg agtacgagtg acatcagcat cactgacaca
     6841 gatcttgcaa acttaaccat tgaagacaat gaagcacagt gttctcaggc aggtgcagtg
     6901 cagccttcgt cttcagtgga aaccaccttt tgtggagctg catcagagcc ttgggcggac
     6961 caacccacag tggcatcttc agctatacca ggtagtttgg gggaagcatt catgaaaaga
     7021 aaaaagacat ttatggaacg atcctaccag agacagagag agatctggaa taaaactccg
     7081 ctccctcaag ccaaagtatc caaagagaag ctatctacaa aggctgttag tggagatgaa
     7141 acagcaaaga gaaacaggag ccagtgtata taagtatgaa gacaagctgt ttttctacag
     7201 aaagcacaag tcaagccaaa aatacatact gacttcctac aaattgtgtt aagggttctt
     7261 ttttaatgta taaaattatt tattgtcaat aaatttttat ttaagtggt
//
