LOCUS       XM_039106868            7995 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus centrosomal protein 250 (Cep250),
            transcript variant X1, mRNA.
ACCESSION   XM_039106868
VERSION     XM_039106868.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_001427194.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7995
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7995
                     /gene="Cep250"
                     /note="centrosomal protein 250; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 15
                     ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 176
                     samples with support for all annotated introns"
                     /db_xref="GeneID:311573"
                     /db_xref="RGD:1562262"
     CDS             256..7542
                     /gene="Cep250"
                     /codon_start=1
                     /product="centrosome-associated protein CEP250 isoform X1"
                     /protein_id="XP_038962796.1"
                     /db_xref="GeneID:311573"
                     /db_xref="RGD:1562262"
                     /translation="METGSPGLNMKPQSLQLVLEEQVLALQQQMAQNQAASWRKLKNS
                     QEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEATGGLIPQRWESVEEPNLEQLLIRL
                     EEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRM
                     EQEFFKGYLRGEHGRLLSVWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTC
                     CLRLTLRAQSRDSSGSGRSDESEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLE
                     KAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQ
                     EEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLV
                     HSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAG
                     QTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEK
                     LEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEE
                     VAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLE
                     QENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAE
                     LRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERA
                     ALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTI
                     IQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEV
                     NRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQAD
                     SALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQA
                     QLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEK
                     VREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQE
                     GQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQL
                     QLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPT
                     PWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLV
                     QRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSR
                     LRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARS
                     ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEV
                     QELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQK
                     LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLAL
                     ELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHS
                     TRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTL
                     QTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDK
                     EKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKE
                     QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQA
                     HVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQ
                     RCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEAL
                     QEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREG
                     EIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQ
                     EKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQL
                     LLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLE
                     RESEQQRLQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVG
                     EKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAG
                     SLEARETMNSSPTQQDGRGSQRGSSDSMLMVELQREVALLRAQLALERKQRQDYIARS
                     VQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETKKLDESLNQSLTSPAPFLHPSLDT
                     TQNTHR"
ORIGIN      
        1 ttagctcggc tgggcggccc ccacaaaagg gcgggagttt ggaggggcgg ggcctggcct
       61 cctggctgag agacgctcag ggcctggcct gcgggctgct gcagcggcct cggttgctgc
      121 ggaccgctac gagatctccg agaaccgacc gtggtgagct caagaggacg tctaagacac
      181 atacagcaat ggttagacac cctcctgcaa tcaacccata gctacacagg aactgcggat
      241 ttgttctgtg agcccatgga gacaggaagc cctgggttga acatgaagcc ccagtcacta
      301 cagctggtgc tggaggagca ggtgctggcc ctgcagcagc agatggcaca gaaccaggct
      361 gcctcctggc ggaagctgaa gaactcccaa gaggcccaga agaggcaagc aaccctcgtg
      421 aggaagcttc aggccaaggt tttacagtac cggagctggt gccaagacct ggagaagcgg
      481 ctagaagcca ctggaggact aatccctcag cggtgggaaa gtgtagaaga gccaaacctg
      541 gaacagctgc tgatccgact ggaggaggag cagcagaggt gtgagagcct agtggaggtg
      601 aacacagagc ttcggctgca catggagaaa gccgatgtgg taaataaagc cctgcaggag
      661 gatgtggaga aactgacagt ggactggagc cgggcccgag acgagttaat gaggaaggag
      721 agccaatggc ggatggagca ggagttcttc aagggctatt tgagaggtga acatggtcgt
      781 cttctcagtg tgtggcgaga ggtggtaacc ttccgacgtc acttcctgaa aatgaagtca
      841 gctactgaca gagatctgac agagctaaag gccgagcacg caaggctttc ggggtcgctg
      901 ctgacctgct gtctgcgctt gaccctgaga gcacagtctc gggactccag tgggtctggg
      961 cgatcagatg agagtgagcc agcccagctg ctgctgcttg tagctaagac ccaggcgctg
     1021 gagaaggaag cccatgagaa gagccaagag ttaatgcagc tcaagagtca aggggatctg
     1081 gagaaggcag agctccagga tcgagtgaca gaactctctg ctctgctaac ccagtctcag
     1141 aaacaaaaca aagattacga agagatggta aaggccctaa gaggaacaat ggagatcctg
     1201 gagacaaacc atgcagagtt aatggaacat gaggcatctc tcagcaggaa tgctcaagag
     1261 gaaaagttgt ctttgcagca cgtgatcaag gatataaccc aggccctggc ctcagtggaa
     1321 gaagaggaca ctgtgaccca aaccccaggt tctgagaact cattgcagtc agactataat
     1381 gacctttccc agtttgattc ccaggaccca aacaaggctc ttactctggt acattccgtg
     1441 ctgactcgga gacagcaggc tgtgcaggac ctcaggcagc agctttcagg ctgccaggag
     1501 gctatgagct tcctgcagca gcagcacaat cagtgggagg aagagggcaa ggccctgagg
     1561 gaaaggctac aaaagctcac tggggagcgt gatgctctgg caggccagac tgtggacctt
     1621 cagggagagg tggactctct cagcaaggag cgggagctgc ttcagacagc caggggtgag
     1681 ctgcagcagc aactagaggt gctggaacag gaggcatggc gactgcgaag agtgaatgtg
     1741 gagctgcagc tgcaggggga ctctgctcaa ggggagaagc tggagcagca ggaggagctg
     1801 cacttggctg tccgtgagag ggagcgcctt caggagacac tggtgggcct ggaagccaag
     1861 cagtcagaat cactaagtga gctgatcgcc cttcgagaag ccctggaatc aagtcgccta
     1921 gcaggagagt tactgaagca ggagcaagag gaagtggctg cagccttggc cagggcagaa
     1981 cagtccattg tggagctatc gagttcggag aacagcctga aggcagaggt agctgatctc
     2041 cgagctgccg ctgtcaagct tggggcctta aatgaggcct tggctttaga taaagttgcg
     2101 ctgaaccagc agcttctcca gttggagcag gagaaccagt ctatgtgcag cagagtggag
     2161 gccgcagagc agttgagaag tgctttgcag gtggacctgg cagaggccga aaggagcagg
     2221 gaagccctgt gggaagagaa gactcacctg gagactcagc tgcggaaggc agaggagaca
     2281 ggcgctgagc tacaggcaga actcaggggc gcccgagaag agaaggaaga acttaaagag
     2341 aagttaaatg aggcacatca ccagcaagaa gcagctacag ctcagctaca gcagctgcat
     2401 caggatgcag aaaggcagga agaagcactg gccagggcag gccaggagaa ggaagcccta
     2461 gtacgggaga gggcagctct tgaggttcgc ctgcaggctg tggagcggga ccgacaggac
     2521 ctcgccgaac aagttctggg gcttaggtca gccaaggagc aactggaggg caatctgttt
     2581 gaggcccaac agcaaaattc tgtgatacag gtcaccaaga gtcagctgga ggtccagatt
     2641 caaactatta ttcaagccaa ggaagtaatt caaggagaag tgaaatgcct gaagctggaa
     2701 ttggatactg agcggagcca tgcagagcag gagcgggatg cagtcgccag gcagctagcc
     2761 caagctgagc aagaggggca agcagctctg gagcgacaga aggtggccca cgaggaggag
     2821 gtgaacaggc tccaagagaa atgggagaag gagcgtgcct tgctgcagca gaagctggat
     2881 aagaccctgg aaaccctaga aagggagaga acagagctgg aaatgaagct gagagagcag
     2941 catacagaaa cggaagctct ccgtgcacag agggaagagg aacgaaccca ggctgacagc
     3001 gctctgtacc aaatgcagct agaaacagag aaggagagag tatccctcct agagacgctg
     3061 ctacagaccc agaaggagct ggcagatgct agccaacagc tggaaaggct gaggcaggac
     3121 atgaaggttc agaagttaaa ggagcaggag accactggca tgctgcaggc ccagcttcgg
     3181 ggggcacagc aagagctgaa ggaggcaatc cagcagcaca gggacgacct tgctgccttc
     3241 cagaaggaca agatagacct gcagaagcag gtagaagact taacatctca gctggtaacc
     3301 cataatgact cccagaggct ggtgaaacaa gagattgaag agaaggtgag agaggctcag
     3361 gaatgtagcc ggattcagaa ggaactggag aaagagaaag ccagcctgac tctgtcactg
     3421 gtggaaaagg aaaaaagact ccttgtttta caagaagctg actctgttcg acagcgggag
     3481 ctggtctcct tgcgccagga catccaggag gcccaggaag ggcaaagaga gctcggtgta
     3541 caggtggagc tcctgaggca ggaggtgaag gaaaaggagg ctgactttgt ggcccgggaa
     3601 gcacagttgc tggaggagtt ggaggcctca cggattgcag agcggcaagt gcgagcgtct
     3661 ctgtgggccc aggaagccaa ggcagcccaa ctgcagctgc agctgcgcag cactgaggcc
     3721 cagctagagg cgctggttgc agaacagcag ccagagaacc aggcgcaggc acagctgagg
     3781 agcctctact ctgtcctgca gcaggccctg gggtctgcat gtgagaggcg gcctgagctg
     3841 aggggtggag gtgattctgt tcctactccg tggggctctg atccagatca gaacggagct
     3901 tcgagactct taaaaagagg gcccctcctg actgcactgt cagctgaggc tgtggcactg
     3961 gctctccaga agcttcatca ggacttgtgg aaggctcagc aggcccggga tgacctaagg
     4021 gaccaggtcc agaagctggt gcagcgcctg actgacacgg aggcccagaa gagccaggtc
     4081 cactcggagc tgcaagacct gcagagacag ctctcacaga gccaggaaga gaaatccaag
     4141 tgggaaggga aacagaactc cctggagtct gagctaaggg acttgcacga gaccatggca
     4201 tccttacaga gccgcctacg gcaggcagag ctacaaaaaa tggaagctca gaatgatcga
     4261 gaattgcttc aggcatccaa ggagaagctg tctgcccagg tagagcatct gcaagcatgt
     4321 gtgacagaag cccgggctca ggcaagtgca gctggtgtcc tggaagaaga tctgcgaacg
     4381 gctcgttctg cgcttaaact gaaaaacgag gagatcgaga gtgaacggga gcgagcccag
     4441 gctttgcagg agcagggtga actgaaggtg gctcagggga aagccttgca ggagaatcta
     4501 accctgctgg cacagaccct gtctaacaga gaacgggagg tcgagacgtt gcaggctgag
     4561 gttcaggaac tggaaaagca gcgggaaatg cagaaggctg ctctggagct gctctccctg
     4621 gacctgaaga agcgcagtcg ggaggtagac ctgcaacagg aacagattca ggagctagaa
     4681 caatgcaggt ctgtcttgga acaccttccc atggccgtcc aagagcggga gcagaagctg
     4741 agtgtgcagc gggaccagat cagagaactg gagaatgacc gggaggccca gaggactgcc
     4801 ttggaacacc agcttctgga ccttgagcag aaggctcaag tgattgagtc ccagagggga
     4861 cagattcagg atctgaaaaa gcaactgggg acactggagt gcctggccct ggaactggag
     4921 gaaagccatc gcaaagtgga gggccagcag aaggtgatca cagaactgga gggccagagg
     4981 gaactgcaga gggtggctct aacccacctc acactggacc tggaagaacg gagccaggag
     5041 ctgcagacac aaagcagcca gctccatgag ctggagaacc atagcacccg tctggcaaaa
     5101 gagctgcagg agagggacca ggaggtgatg tctcaacgcc agcagattga ggagctacaa
     5161 aagcagaaag aacagctgac tcaggaccta gagaggaaag gccaagagct ggtgctgcag
     5221 aaggaaagga ttcaggttct ggaagatcag aggacgctgc agaccaagat cttagaagag
     5281 gacctagaac agatcaagca ttccctgaga gaacgtggcc aggagctggc ctctcagtgg
     5341 cagctgatgc aggagcgggc agaggatgga aagagcccga gtaaagccca gcgagggagc
     5401 ctggagcatt tgaagctgat cctgcgtgat aaggagaagg aggtggagtg ccagcaggag
     5461 cgcatccagg aacttcagga gcacatgggc cagctggaac agcagctcca ggggctgcac
     5521 aggaaggtgg gtgagacgag cctgctcctg acccatcgag agcaagagac ggcaaccctg
     5581 cagcagcgcc tccaggaagc caaggaacag ggggagctga gagagcaggt gcttcagggt
     5641 cagctggagg aggcgcagag agctctggcc cagagggacc atgaactaga ggccctccgg
     5701 caggaacagc agcagacccg gggccaggag gaaagcatga agcagaagac aagtgctctg
     5761 caggccgcgc tggagcaggc gcatgtgaca ctgaaggagc gtcaggggga gctggaagaa
     5821 caccggggac aggtgcaaag gctccaggaa gaactaatag tagagggacg gcaggtacgg
     5881 gccctggagg aggtgttggg agacctaaga gcggagtctc gggaacacga gaagaccgtg
     5941 ctggcccttc agcaacggtg tgctgaacag gcccaggaac atgaggcaga agccaggacc
     6001 ctgcaggaca gctggctgca ggcccaggcc acactcgcag aacaggagca agagctagag
     6061 gctctgcgag cagaaaacca gtattcccgc caacaggagg aggctgcatt tggccaggca
     6121 gaggctcttc aggaggccct cagtaaagcc caagccaccc tgcaggagaa agagcagagg
     6181 ctccttgagc aggctgaatt gagctgcact cttgaggcca gcactgccac cttgcaagct
     6241 acactggaca cctgccaggc acgcgcccgg cagctggaag aggccttgag ggttcgggaa
     6301 ggtgagatcc agacccaggc tctccaacac caggaggcta tgcagcacct ccagcaggaa
     6361 ctttgccaga aggaagaaga tctgaggcaa caggatgagc agaggcagct actagagaag
     6421 gctgtggccc agaggagtca agaaaatgga atccaggaga agcaaagtct ggagcaagag
     6481 aaagaagagg aaacacgggg acttcttgag agcctaaagg agctacagct gactgtagcc
     6541 caaaaggaag aagagattct gatgctgagg gaggcccagc aaaggcagaa tcaggaggcc
     6601 tcttccccaa gccacaggtc cttcccagcc gagaagccat ctctacaact gctcctagcg
     6661 cagcaggatc tggagcggct gcagaatgcc ctaaggcaaa cagaggccag ggagattgaa
     6721 tggagggaga aggctcaggg cttggccctg tccctggccc aaagcaaggc cagcatcagc
     6781 agtctgcagg agatagccat gttcctacaa gcctctgtcc tagagcggga atcagaacaa
     6841 caaagactgc aggaggagtt ggtactcagc agacaggctc tggaagagca gcagtcacgt
     6901 ggcccacact catccagcag agcagaccag gggcccaaag ctggacagga cacagagccc
     6961 ggagaggtaa tagaggctga gcccagtcct ggagtggggg agaaggaaca gttaagacag
     7021 aggcttgaac gtctgcagca agcggtggca gagctggaag ttgaccggag caagctgcag
     7081 tgccacaatg cgcagctgcg gaccaccttg gagcaggtgg agcgagagcg gaggaagctg
     7141 aagagggatt ctttgcgtgc atcacgggca gggtcgctgg aggccagaga aacaatgaat
     7201 tcatccccaa cacagcagga tgggagagga agtcagaggg ggtcctcgga cagcatgctt
     7261 atggttgagc ttcaaagaga ggtagccctg ctgcgagccc aactggcctt ggagcgaaag
     7321 cagaggcagg actacatcgc acgatccgtg cagaccagcc gtgagctagc aggcctgcat
     7381 cacagcctgt ctcactccct cctcaccgtg gcccaggccc ctgaggccac tgttctggag
     7441 gccgagacga aaaagctgga tgagtctctg aatcagagtc tgacatcccc agcgccattc
     7501 ctacatccca gtctggacac tactcaaaat acccacaggt agtagccata ggcagggcag
     7561 gacacaagcc aggtggtaca tcagacgact gcagagggtc acagcccccg acccagctac
     7621 agatttgcca aaggcaagat ttagctgtta cccaacctga gatacccagc cagccgacag
     7681 tcccaggaag aaaacaagaa ccttccaggc tggagaagag tccagttcac atgggagcga
     7741 gccaagtcac atttccttgc taacctactg ttacccaaga agtgccttgc cctgactaca
     7801 gggcatctgt tgtctttcta cccgatgaag cagccatgat ctacactaag cctgaagacc
     7861 caacaacatg tgggtattcc gtcctgggca ggagcagcct gaatgtatgg aataagggag
     7921 cgtccccggc cacttgtctt cggtgtctcc cttcccttcc ttcccttcaa cagtaaatcc
     7981 taggtctttg catta
//
