LOCUS       NM_138865               1676 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus centrosomal protein 19 (Cep19), mRNA.
ACCESSION   NM_138865
VERSION     NM_138865.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1676)
  AUTHORS   Kanie,T., Abbott,K.L., Mooney,N.A., Plowey,E.D., Demeter,J. and
            Jackson,P.K.
  TITLE     The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate
            Intraflagellar Transport at the Ciliary Base
  JOURNAL   Dev Cell 42 (1), 22-36 (2017)
   PUBMED   28625565
REFERENCE   2  (bases 1 to 1676)
  AUTHORS   Nishijima,Y., Hagiya,Y., Kubo,T., Takei,R., Katoh,Y. and
            Nakayama,K.
  TITLE     RABL2 interacts with the intraflagellar transport-B complex and
            CEP19 and participates in ciliary assembly
  JOURNAL   Mol Biol Cell 28 (12), 1652-1666 (2017)
   PUBMED   28428259
REFERENCE   3  (bases 1 to 1676)
  AUTHORS   Mojarad,B.A., Gupta,G.D., Hasegan,M., Goudiam,O., Basto,R.,
            Gingras,A.C. and Pelletier,L.
  TITLE     CEP19 cooperates with FOP and CEP350 to drive early steps in the
            ciliogenesis programme
  JOURNAL   Open Biol 7 (6) (2017)
   PUBMED   28659385
REFERENCE   4  (bases 1 to 1676)
  AUTHORS   Shalata,A., Ramirez,M.C., Desnick,R.J., Priedigkeit,N.,
            Buettner,C., Lindtner,C., Mahroum,M., Abdul-Ghani,M., Dong,F.,
            Arar,N., Camacho-Vanegas,O., Zhang,R., Camacho,S.C., Chen,Y.,
            Ibdah,M., DeFronzo,R., Gillespie,V., Kelley,K., Dynlacht,B.D.,
            Kim,S., Glucksman,M.J., Borochowitz,Z.U. and Martignetti,J.A.
  TITLE     Morbid obesity resulting from inactivation of the ciliary protein
            CEP19 in humans and mice
  JOURNAL   Am J Hum Genet 93 (6), 1061-1071 (2013)
   PUBMED   24268657
REFERENCE   5  (bases 1 to 1676)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Feb 10, 2021 this sequence version replaced NM_138865.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF146738.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-278               JAXUCZ010000011.1  82191755-82192032   c
            279-356             JAXUCZ010000011.1  82187871-82187948   c
            357-550             JAXUCZ010000011.1  82186846-82187039   c
            551-1676            JAXUCZ010000011.1  82182868-82183993   c
FEATURES             Location/Qualifiers
     source          1..1676
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..1676
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /note="centrosomal protein 19"
                     /db_xref="GeneID:192229"
                     /db_xref="RGD:621352"
     exon            1..278
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /inference="alignment:Splign:2.1.0"
     exon            279..356
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /inference="alignment:Splign:2.1.0"
     exon            357..550
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /inference="alignment:Splign:2.1.0"
     CDS             385..912
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /note="testis specific protein"
                     /codon_start=1
                     /product="centrosomal protein of 19 kDa"
                     /protein_id="NP_620220.2"
                     /db_xref="GeneID:192229"
                     /db_xref="RGD:621352"
                     /translation="MRSPVYPELHETMKYIAKKCGVRFQPPAMILIYENEAEGKSRQR
                     IMPVRNFSKFSDCTRAAEQLKNNPRHKSYLEQVSLKQLEKLFVFLRGSLQGQSLAETM
                     EQIQRETTIDPEEDLNKLDDKELAKRKSIMDELFEKNQKRKDDPSFVYDVEVEFPQDE
                     QLLSCSWDTASVDEF"
     exon            551..1676
                     /gene="Cep19"
                     /gene_synonym="RGD621352"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaacgatctt tggggcgccc tggcgggccc tggacccgac gagctgcttt aggaccgcat
       61 tcgccgcgct cagccccgct tcctgtcctc aaccggatgc gtgcgggccg ggccccctgc
      121 cgctgaattc accccatggt tactcctgta ggctatggct gtcgccgctt cctgcagggt
      181 caggctccac ctcgcctcaa agtcgatcta agtgctcctc tgtgcaaggc gataggatgg
      241 aaaccatccc ctcactgctg ttcagatttt cacgtcctac atgtactaag agcttaatga
      301 aaatggacac acttcctgcc ttcctagagc aaatagaata acagggagga tacatggaaa
      361 ttgttgcaca gctgtcctat ctgtatgaga tctccagttt accctgagtt acacgagacg
      421 atgaaataca ttgccaagaa gtgtggagtt aggttccagc ctccggccat gatcttgatt
      481 tatgagaatg aagctgaagg aaagagccgc cagcgcatca tgcctgtccg aaacttttcg
      541 aagttctcag attgcaccag agctgctgaa caattaaaga ataacccacg gcacaagagt
      601 tacctggaac aggtgtccct gaagcagctg gagaagctgt ttgttttttt acgaggttcc
      661 ctacaggggc agagcctggc agaaacaatg gaacagatcc agcgggaaac aaccattgat
      721 cccgaggaag acctgaacaa actggacgac aaggagctcg ccaaaaggaa gagcatcatg
      781 gatgagcttt tcgagaaaaa tcagaagaga aaggatgacc ccagttttgt gtatgacgtg
      841 gaggttgagt tccctcagga tgagcagctg ctgtcctgca gctgggacac agcatccgtc
      901 gatgagttct gagactacgc cacgtttcca caaagaagga agagcggttc tagaaaacac
      961 tgagacacga atgatccgta aaaccaagac acttaacatg tcctacacag ccctatgaga
     1021 aacacagaaa cacaagatag gaatctgcaa tctaaagaga aagtaactcg agaacttgta
     1081 aaaaggtatt ttattatatt actcaggaaa aagctaagag ccaggtattt gatgaaggct
     1141 gtagaaaggt caatacctgc ttgaccttga aatgctacag atgtatttta tagaaatcga
     1201 gatgaagcaa agggggaagg gggaagtaaa gagacaagaa ataggaaaat ctgggaaagg
     1261 gtgagtaatt atagtttgac aagactagaa ttaacctgtg ctcattagga ccctgtgtgc
     1321 attaactctg gggtagacag gaatacctat aaatgcaaaa tgtctcacag ctacaagtac
     1381 atgtggcaga aggcaggcaa gtctactccg cgatcaggaa atgtgttcta acgttactct
     1441 gaaacccaga gccacttcct gtgaaagact ggtttgtaca atgggaagtc tgcccacaat
     1501 gagcgatagg tgctgctgtt cagacctgtt cgtaagttta gttgtgcaaa gatcgcagcc
     1561 tcacaaggcc tctgtgtgca gatgtgtttg ttcttactag aatgttatct gattgataga
     1621 aatcatatgt tttctacaag gaaaccatta cgcatcgaat aaagccgtga atgcaa
//
