LOCUS       NM_001398887            5825 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus centrosomal protein 135 (Cep135), mRNA.
ACCESSION   NM_001398887 XM_006250875
VERSION     NM_001398887.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5825)
  AUTHORS   Chang,C.W., Hsu,W.B., Tsai,J.J., Tang,C.J. and Tang,T.K.
  TITLE     CEP295 interacts with microtubules and is required for centriole
            elongation
  JOURNAL   J Cell Sci 129 (13), 2501-2513 (2016)
   PUBMED   27185865
REFERENCE   2  (bases 1 to 5825)
  AUTHORS   Hori,A., Morand,A., Ikebe,C., Frith,D., Snijders,A.P. and Toda,T.
  TITLE     The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome
            and ensures proper spindle length and orientation
  JOURNAL   Biochem Biophys Res Commun 468 (1-2), 39-45 (2015)
   PUBMED   26545777
REFERENCE   3  (bases 1 to 5825)
  AUTHORS   Zhu,M., Settele,F., Kotak,S., Sanchez-Pulido,L., Ehret,L.,
            Ponting,C.P., Gonczy,P. and Hoffmann,I.
  TITLE     MISP is a novel Plk1 substrate required for proper spindle
            orientation and mitotic progression
  JOURNAL   J Cell Biol 200 (6), 773-787 (2013)
   PUBMED   23509069
REFERENCE   4  (bases 1 to 5825)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   5  (bases 1 to 5825)
  AUTHORS   Kim,K., Lee,S., Chang,J. and Rhee,K.
  TITLE     A novel function of CEP135 as a platform protein of C-NAP1 for its
            centriolar localization
  JOURNAL   Exp Cell Res 314 (20), 3692-3700 (2008)
   PUBMED   18851962
REFERENCE   6  (bases 1 to 5825)
  AUTHORS   Kleylein-Sohn,J., Westendorf,J., Le Clech,M., Habedanck,R.,
            Stierhof,Y.D. and Nigg,E.A.
  TITLE     Plk4-induced centriole biogenesis in human cells
  JOURNAL   Dev Cell 13 (2), 190-202 (2007)
   PUBMED   17681131
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Dec 27, 2021 this sequence version replaced XM_006250875.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.51520.1,
                                           SRR26643293.56597.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               JAXUCZ010000014.1  31949820-31950050   c
            232-388             JAXUCZ010000014.1  31946736-31946892   c
            389-579             JAXUCZ010000014.1  31945008-31945198   c
            580-747             JAXUCZ010000014.1  31944203-31944370   c
            748-889             JAXUCZ010000014.1  31943208-31943349   c
            890-974             JAXUCZ010000014.1  31941366-31941450   c
            975-1103            JAXUCZ010000014.1  31937187-31937315   c
            1104-1319           JAXUCZ010000014.1  31935373-31935588   c
            1320-1385           JAXUCZ010000014.1  31931815-31931880   c
            1386-1524           JAXUCZ010000014.1  31928965-31929103   c
            1525-1748           JAXUCZ010000014.1  31926444-31926667   c
            1749-1901           JAXUCZ010000014.1  31923026-31923178   c
            1902-2054           JAXUCZ010000014.1  31921945-31922097   c
            2055-2132           JAXUCZ010000014.1  31918158-31918235   c
            2133-2284           JAXUCZ010000014.1  31914789-31914940   c
            2285-2400           JAXUCZ010000014.1  31908892-31909007   c
            2401-2555           JAXUCZ010000014.1  31908664-31908818   c
            2556-2611           JAXUCZ010000014.1  31908192-31908247   c
            2612-2780           JAXUCZ010000014.1  31907337-31907505   c
            2781-2891           JAXUCZ010000014.1  31905947-31906057   c
            2892-3077           JAXUCZ010000014.1  31905253-31905438   c
            3078-3287           JAXUCZ010000014.1  31895926-31896135   c
            3288-3490           JAXUCZ010000014.1  31894960-31895162   c
            3491-3595           JAXUCZ010000014.1  31894045-31894149   c
            3596-3720           JAXUCZ010000014.1  31890491-31890615   c
            3721-5825           JAXUCZ010000014.1  31884781-31886885   c
FEATURES             Location/Qualifiers
     source          1..5825
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..5825
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /note="centrosomal protein 135"
                     /db_xref="GeneID:305288"
                     /db_xref="RGD:1310726"
     exon            1..231
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            232..388
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..3698
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /note="centrosomal protein 135kDa"
                     /codon_start=1
                     /product="centrosomal protein of 135 kDa"
                     /protein_id="NP_001385816.1"
                     /db_xref="GeneID:305288"
                     /db_xref="RGD:1310726"
                     /translation="MTTAAERKYINIRKRLDQLGYRQTLSVDSLPLVEKLFSDLVHTT
                     ESLRQCRLSSVKAEKDSANFDFVLEPYKLENTRLNKENNELYLELMKLREYSDKHIKD
                     LKITLKKSSRETADLKFLNNQYVHKVRLLEKESKAKDEKIQQLQEKNLRAVVQTPGGR
                     KRNIAFRRQRMQIDEPAPPSEVSSYPVPQPEDPYIADLLQVADNRIQELQEEVHQLQE
                     KLAQMEKGVQDYSRQIELREREIERLSVAVDGGRSPDILSLETRNKTNEKLIAQLNIQ
                     VDFLQQANKELERRIQELMETKATVTTEVVNLSNRNEKLCQELTEIDQMAQQLERHKE
                     QVLETADRELGEAKKEIKRNLSEMRNLEEKMSKLQWELDVSNKEKERLNGELLLKSDL
                     ETVVHQLEQEKQRLNKKLQSFAVTERELTLEVERMRLEHGIKRRDKSPSRLDTFLKGI
                     EDERDYYKKELEKLQHLIQRRSCSVIYCAREKPPIIKCSEKGDCNSDIHLITRERDEL
                     QRMLERFEKYMEDIQSNVKLLTAERDRLSVLYKEAKEELSALRQESTGSLAPNNLVSC
                     IEKEKERALSDLRRITAEKEALREKLKNIQELNVVGKSELEKTIEHLTYINHQLENEK
                     YELQSKILIMKETIESLESKSKLQAQKLSHVTGDSSHQKTEMNSLRIVSEQLQRSLDD
                     CQHRLSIKRGELESAQEQIKALEQKLESLSHRMTMQSEETHAMKKTIGVMDKEKDFLQ
                     ETVDEKTEKIASLQDSLISKEKAITQLKVTVSECESSLNQLQETLTNRDREINSLRRQ
                     LDATHKELDDVGKSREISYKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVH
                     KYITEVSRWESLMAAKEKENKDLLDRFQMLHNRAEDWEIKAQQAEGENSSVRLELLSI
                     DTERRHLRERVELLEKEIQEHINAHHAYESQISSMAKAMSQLEEELRRHESEKATVLG
                     DVSSLRELCIKLDSGKDIMTHQLNSKGLELERAVAELENVKSESELLKKQLMTERQTI
                     NSLESLLATNRDKEFQSHLTSHEKDTEIQLLKEKLNLSESKLTTQSRETSMLRTKVTQ
                     LQTDYDNLKRLMSNEKYERERAIQELRRLGLPTSPLSSTLRSPMQSPEHINA"
     exon            389..579
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            580..747
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            748..889
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            890..974
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1103
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1319
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1385
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1524
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1748
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1901
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..2054
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2132
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2284
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2285..2400
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2401..2555
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..2611
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2780
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2781..2891
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..3077
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            3078..3287
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3490
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            3491..3595
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            3596..3720
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
     exon            3721..5825
                     /gene="Cep135"
                     /gene_synonym="RGD1310726"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgaggccga gagccgccat ctccgccggg cgcgcgcgcc gccactgtgg gtagctccgg
       61 tccgttaccg gggcaaccgc ggcgctccct ccttgtgggc cgcgaccgtc tctccgcgcc
      121 attttcaaac tgcgttcgtg tccgagccat tggccgcagc gggaggagac agcgaggacg
      181 gtgggtcccg agggcgatgc gcctcgggac ggggcggctg cggcagcaac gggctttaag
      241 tttggagtct gactgaaact ggttttggaa gcaagatgac tacagctgca gagagaaagt
      301 atattaacat taggaaaagg ttagaccagc tgggctaccg ccagaccctg tcagtggaca
      361 gtctgccttt ggtagaaaaa cttttcagtg atttggttca cacaacagaa agcctgcggc
      421 aatgcaggct gtcctcggta aaagcagaaa aggacagtgc caatttcgat tttgttctgg
      481 aaccttataa acttgaaaac acaagactga ataaggagaa taatgaattg tatctggagt
      541 taatgaagct gagagaatac tcagacaagc acattaaaga cttgaaaatc acactgaaga
      601 aatcctcacg agagacagct gatctgaagt ttctgaataa ccagtatgtc cacaaggtca
      661 gactcctgga gaaagagagc aaagctaagg acgaaaaaat ccagcagctt caagaaaaaa
      721 atctgcgtgc ggtagtacag actcctgggg gcaggaaaag aaacattgcg tttaggcgcc
      781 agcggatgca aatcgatgag ccagccccac cctcggaagt cagctcctac ccagttcctc
      841 aaccagaaga cccgtacatc gcggacctcc tgcaagtggc tgacaatagg attcaggagc
      901 tgcaggagga agtgcaccag ctgcaagaga aactagcgca gatggagaaa ggagtgcagg
      961 actacagcag gcagatcgaa ctaagagaac gagaaataga gcgactgtcc gttgctgtgg
     1021 atggcggccg ttcccctgac atcctgtctc tggagactag aaataaaacc aacgagaagc
     1081 ttattgctca gttaaatatc caggttgact tccttcaaca agctaataag gaactggaga
     1141 ggcgtatcca agagctcatg gagaccaagg cgacagtgac aactgaggtt gtgaacctaa
     1201 gcaacagaaa cgaaaagctc tgccaggaac taacagaaat cgaccagatg gcccagcagc
     1261 tggaaaggca caaggaacaa gtgctggaga cggcagacag ggagctcggg gaggcaaaga
     1321 aagagattaa aagaaacctc tctgaaatgc ggaaccttga ggaaaaaatg tcaaaactgc
     1381 aatgggaatt agatgtaagc aataaggaga aggagagact gaatggtgaa ctacttttaa
     1441 agtcagacct ggagacggtt gttcatcagc ttgaacaaga aaagcaaaga cttaacaaaa
     1501 aactgcagag ttttgcagtc acagaaagag aactgactct ggaggttgag aggatgaggc
     1561 tagaacacgg gataaaacgt cgagacaagt cgccctcccg tctagacaca tttctgaaag
     1621 gcatagagga cgagcgcgat tattacaaga aagagctgga gaaactgcag catctcatcc
     1681 agcgaagatc atgctctgtt atttactgtg ctcgggagaa acctcctata atcaaatgct
     1741 cagaaaaggg tgactgcaat tccgacattc atctgatcac aagagaaagg gatgagcttc
     1801 agcgcatgct agaaagattt gagaaataca tggaggatat acagtccaac gtgaaactgc
     1861 tgacggcaga aagggacaga ctaagtgtcc tgtataagga agcaaaggaa gagttatctg
     1921 cactaagaca ggagtccact ggttcactgg cccccaacaa tcttgtaagt tgtatagaaa
     1981 aggagaaaga acgcgcatta tctgacttaa gaagaattac agcagaaaag gaagctctga
     2041 gagaaaagtt gaaaaatatc caagaactga atgttgttgg aaaatcagaa ttagagaaga
     2101 ctattgaaca tttgacgtat attaatcacc agcttgaaaa tgaaaaatat gaattacaat
     2161 ctaaaatatt aataatgaaa gaaacaatag aatcattaga gagcaaatca aaactccaag
     2221 ctcaaaaact tagccatgtg actggtgact catctcatca gaaaacagag atgaactcgc
     2281 tcaggatagt gagtgagcag ctacagcggt cacttgatga ctgtcagcac cgactttcca
     2341 taaaaagagg tgaactcgaa tcagcccaag aacaaattaa agcgctggag cagaaactag
     2401 agtctctgag ccacaggatg acaatgcaaa gcgaagaaac tcatgcgatg aagaagacca
     2461 ttggcgtgat ggacaaagaa aaggactttc tccaggagac tgtggatgag aagacggaaa
     2521 agatcgccag cctgcaagac agcctcatta gtaaagaaaa agctattacc cagttgaagg
     2581 tcacagtctc ggagtgtgaa tcgtcactga accaactaca agaaactttg actaatcgag
     2641 accgagagat aaacagcctc cgtcgccagc ttgatgcaac tcacaaggaa cttgacgatg
     2701 ttgggaaatc tagagagatc tcttataagg aaaatagaag gttacaagat gacctggcca
     2761 caatggcgag agaaaaccag gagatctcac tggaactgga agcagcagtg caagagaaag
     2821 aagagatgaa gagcagggtt cacaagtata tcactgaggt gtcacgatgg gagagcctaa
     2881 tggccgcgaa ggaaaaagaa aacaaagact tgctagatag attccagatg cttcacaacc
     2941 gtgctgagga ctgggagatc aaagctcagc aagcggaggg ggagaacagc tcagtccgcc
     3001 tagagctgct gtctattgat acagagagaa ggcacctgcg agagcgggtg gagctcctgg
     3061 agaaggagat ccaggagcac ataaatgcac atcacgctta tgagtctcag atctcatcaa
     3121 tggctaaagc catgtctcag ttagaagaag agcttcgacg acatgagagt gagaaagcca
     3181 ccgtgttagg tgatgtgtcc tctctccgag aactctgcat taagctcgac tcaggcaaag
     3241 acattatgac ccaccagctg aattccaaag gccttgagct ggagcgggca gtagcagagt
     3301 tggagaatgt aaaatcagaa tcggagctgt taaaaaagca gctgatgact gagaggcaga
     3361 caattaacag ccttgagtcg ttgttagcta caaacagaga taaagaattc cagtcccacc
     3421 taacctccca cgagaaggac acagaaatcc agctgctgaa ggagaagtta aacctctcag
     3481 aaagcaaact aactacccaa agccgagaaa cctccatgct tcgaactaaa gtgacacagt
     3541 tgcagacaga ttatgataat ctgaaaaggc tgatgtcaaa tgagaagtac gaacgagagc
     3601 gagcaatcca agagctgcgc cgactcggtc ttcccacgtc gcctctgagc tccactctga
     3661 gatcgcccat gcagtctcct gagcatataa atgcatagtt atcggaaagg aatgcaccag
     3721 attatggttt tcagtgagtt tctacatgga ttttcataag aacacaggag taatgagata
     3781 tttgaagtac ttgttcctgc gaatcatgaa caatgacaca aattatacct ctgtcagcct
     3841 ttatttaaat cagtggatat ttatgtaaaa atgtttagtt ttaaagagcc ttatgtatat
     3901 tttcatatgt gaaaaaaaca gaatatgtat taatagctta agtgatgtga tatgtgaatc
     3961 tttattattc ccaactaaaa ttactcctta aaatgtgttt ataccatgaa ttaatttaac
     4021 gtgtttacat tatgttgtag taatctgtgc cttaatgaac cacactgtat gcatgtaact
     4081 actcttgcac tatgtagaca tgtttggttt tcatgcctgt ttggagccca aggcatgatg
     4141 aggtcagagc atgacccatt tgattctcct acgcgtggca tcaatccacg tgtgctgtcc
     4201 ttcgtacagg cagtctactt acgtctggtc tgttggcaga actcgttttt attattattt
     4261 ttttttatgt gaaagaaagg gttttaagtg agcttatggt tccagagagc caggagtcca
     4321 ccaagtgcac aaggcggcgg cagcaagcac acaacaggaa gcggagagtg aacaaacagg
     4381 aagtcaggag accctgtgtt ctccatcagc cctccccccg ggacacactt gctccagtaa
     4441 atctgcccct cttacacctc cccagacagc acccctcaca actggggcca agtgctcaag
     4501 gatctgagat atgggatatg tttctcattc agactacaat ttccaaaacc aaaaattcaa
     4561 ccgatagcat atcttttttc ttgaggtgtt tttgttattt ctgaaagttc agacctatta
     4621 gagatcaaca aactgagtta cctgtttgaa aaattactca tattctcatc aactttgaaa
     4681 atcttttcct ggatatagag ggaatccacc tagtgacttc attacagagc gctggatgaa
     4741 tgagtgcaag caggaaggac ggcagtggga ggcacgtcta tctatgtggg tcttacttgg
     4801 ctgtcttgtg gctctccaca tgatgcagtt ttttaagaat taagctaaaa tatattcaga
     4861 gttttgtaaa acaatcaaac aaaaatttgg agtgtatttt ttactaatta aattcttcag
     4921 tgtactagtc taaaacttca gaatatgaaa gcatatgaag taaatgtaga aaagtggttt
     4981 tgctaaaagc ccactgtgca tccgacaaca cctatttgtg gccttgagtc ctgcataact
     5041 tacccagtct ttcagaatag tgcgcagaca ccctcccctg gcatataaac cgagaacagc
     5101 tttttacaat tccactttca aggttagaac tccaaagaat ttaaggtgtg ccaaccccta
     5161 gacaagagca gaaatacaaa ataaaatgtc agatacaaat actaaccata taccaactgc
     5221 tcacatttga agaaaatcct ttaaaactag atctcatcat gactgaggaa gaacttaaaa
     5281 gtcagcatgg gcaggcaagg cagcttcccc ctggcttagc acagttgctc agtgtgaacg
     5341 tccctgaggg gcataggcct ccgagtaacc agggcacctt gcatgttccc gatgttccct
     5401 ttgcaagaat ttgctgcgta tttgagtata ggatgactta ctctcccacc atttttacaa
     5461 ttttatcatt ttatttcctt tgagtaaatt catgttttat agcaaaatac aaaaaaaaaa
     5521 aagaccattt acaacatcat ttggaaggtt ttgtaataga gacatgtgat aaaatatttg
     5581 tctccaccct ttctcccaaa gcaacagcaa ggcacactct cttaaatgtt cacttttagt
     5641 gttcgctgta atataaattt gttgccttca aactcgttat tttataacca tcatactaca
     5701 gtttttttaa agtgattatc atttaaaaac tgaatgttct ttttatagat gtttttactt
     5761 ttatcttaaa taattttaaa tcatggagtt tgattataga cttaccaata aacataccag
     5821 tcaat
//
