LOCUS       NM_001108310            3600 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus centrosomal protein 131 (Cep131), mRNA.
ACCESSION   NM_001108310 XM_001081778 XM_340945
VERSION     NM_001108310.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3600)
  AUTHORS   Airik R, Schueler M, Airik M, Cho J, Ulanowicz KA, Porath JD, Hurd
            TW, Bekker-Jensen S, Schroder JM, Andersen JS and Hildebrandt F.
  TITLE     SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is
            Required for Hedgehog Signaling
  JOURNAL   PLoS One 11 (5), e0156081 (2016)
   PUBMED   27224062
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3600)
  AUTHORS   Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L,
            Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ,
            Walsh CA and Reiter JF.
  TITLE     Centriolar satellites assemble centrosomal microcephaly proteins to
            recruit CDK2 and promote centriole duplication
  JOURNAL   Elife 4, e07519 (2015)
   PUBMED   26297806
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3600)
  AUTHORS   Chamling X, Seo S, Searby CC, Kim G, Slusarski DC and Sheffield VC.
  TITLE     The centriolar satellite protein AZI1 interacts with BBS4 and
            regulates ciliary trafficking of the BBSome
  JOURNAL   PLoS Genet 10 (2), e1004083 (2014)
   PUBMED   24550735
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3600)
  AUTHORS   Hall EA, Keighren M, Ford MJ, Davey T, Jarman AP, Smith LB, Jackson
            IJ and Mill P.
  TITLE     Acute versus chronic loss of mammalian Azi1/Cep131 results in
            distinct ciliary phenotypes
  JOURNAL   PLoS Genet 9 (12), e1003928 (2013)
   PUBMED   24415959
REFERENCE   5  (bases 1 to 3600)
  AUTHORS   Staples CJ, Myers KN, Beveridge RD, Patil AA, Lee AJ, Swanton C,
            Howell M, Boulton SJ and Collis SJ.
  TITLE     The centriolar satellite protein Cep131 is important for genome
            stability
  JOURNAL   J Cell Sci 125 (Pt 20), 4770-4779 (2012)
   PUBMED   22797915
REFERENCE   6  (bases 1 to 3600)
  AUTHORS   Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I,
            Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA
            and Andersen JS.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   7  (bases 1 to 3600)
  AUTHORS   Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA and Mann
            M.
  TITLE     Proteomic characterization of the human centrosome by protein
            correlation profiling
  JOURNAL   Nature 426 (6966), 570-574 (2003)
   PUBMED   14654843
REFERENCE   8  (bases 1 to 3600)
  AUTHORS   Aoto H, Tsuchida J, Nishina Y, Nishimune Y, Asano A and Tajima S.
  TITLE     Isolation of a novel cDNA that encodes a protein localized to the
            pre-acrosome region of spermatids
  JOURNAL   Eur J Biochem 234 (1), 8-15 (1995)
   PUBMED   8529672
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_340945.3, XM_001081778.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3600
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.3"
     gene            1..3600
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /note="centrosomal protein 131"
                     /db_xref="GeneID:360672"
                     /db_xref="RGD:1307745"
     exon            1..161
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            162..355
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..3388
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /note="5-azacytidine-induced protein 1; 5-azacytidine
                     induced 1; 5-azacytidine induced gene 1"
                     /codon_start=1
                     /product="centrosomal protein of 131 kDa"
                     /protein_id="NP_001101780.1"
                     /db_xref="GeneID:360672"
                     /db_xref="RGD:1307745"
                     /translation="MKGSRTISATPEGSPEGMDLSLIGLPLPMSQRPGSASAAKSIFR
                     SVSVATGSEPRKKALEATGPGGPRAINNLRRSNSTTQVNQSWTGSPRPAEPTDFLMLF
                     EGSTSGRRRVASFSKVSSEKGATWNVLDDQPRDFASPANSQSPSTLDSALGPRRKECS
                     LAPSFTANNRSNKGAVGNCVTTMVHNHYASSKKVSPPKSSNQTAPSLNNIVKAAAREG
                     GEGSDFGKPRKNFSSVSQSTRGTTGLLRRKEVTEEEAERFIQQVNQAAVTIQRWYRCQ
                     VQRRRTGAASLEHLLASKREGQRQRLGSGNLLDLHRQEEAARKKAREEKARQARQAAI
                     QELQQKRAQKAREVEHRPPKERPETRALEQPRPTQEPPSMPSSVTHPKANNAGASLYP
                     TGPADPCPPASESFPERQPSLEDKPQDAHSQVEAREDLAALASTRSKTRARATLDDLL
                     DTLKLLEEEPEPLLHPKAYRQDRYAWMDEEEDTNPLTADNLEKFGKLSAAPGPPDDGT
                     LLSEAKLQSIMTFLDEMEKSGQERPAPWRESLVLEAGPRSLELGSEGTTSVMRLKLEL
                     EEKKQAMVLLQRALAQQRDLATRRVKETEKELSRQLRQQKEQYEATIQRHLSFIDQLI
                     EDKKVLSEKCEAVVAELKQGDQRCRERVAQVQEQHELEIKKLKELMSATEKIRREKWI
                     NEKTKKIKEITVRGLEPEIQKLIAKHKQEVRRLRGLHEAELQQREEQAAQRHLRQAEE
                     LREHLEREREALGQQERERAQQRLEQHLEQEQRALEQQRRRLYTEVAEEKERLGQQAA
                     RQRVELEELRQQLEESSAALTRALRAEFERSREEQERRHQMELKALKDQLEAERQAWV
                     ASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAENRVKR
                     VRDKYETELSELEQSERKLQERCTELKGRLGEAEGEKERLQSLLRQKEKELDDLRVVN
                     TQMCSERASLAQVVRQEFAEQLAASQEETQRVKAELAELRARQQMELDEVHRRVKTAL
                     ARKEAAVNSLRKQHEAAEKRADHLEELLEQHKGPSLSSK"
     exon            356..450
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            451..565
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            566..687
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            688..801
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            802..948
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1066
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1183
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1337
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1432
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1615
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1792
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1918
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2044
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2161
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2264
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2466
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2467..2574
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2575..2692
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2767
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2910
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2911..3088
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3089..3252
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3253..3313
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3314..3600
                     /gene="Cep131"
                     /gene_synonym="Azi1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccaggctgg ttgctagccg ccgccgctcg cccctgcgga cagcgcttta ttgtcaccca
       61 cggcggaggc cgcgccagcc cggtggggcc ccggctggct ctgcagccgc gcccgccagg
      121 ccgagcccac gggccctgcg ccccaggctg ggtccgcgca gggctagcct ggtccaccat
      181 gaaaggttca cggaccatca gtgccactcc cgaaggcagt ccagaaggta tggacttgag
      241 tctgattggc ctccctctac ccatgtccca gcggcccggc agtgcctctg ccgcaaagtc
      301 tattttccgc tccgtgtctg tggccacagg cagtgagccg agaaaaaagg cactggaggc
      361 cactgggcct gggggccccc gagctatcaa caatcttcga agatccaaca gtactacgca
      421 ggtcaaccag tcatggaccg gctcccccag gccagcagag cccaccgact tcctaatgct
      481 ctttgagggt agcaccagtg ggagaagaag ggtggccagc tttagcaagg tgtccagcga
      541 gaagggagcc acgtggaatg tcttggatga ccagcctagg gactttgctt caccagccaa
      601 cagtcagagt cccagcaccc ttgactctgc cttgggccca cggaggaagg agtgttccct
      661 agcgcccagc ttcactgcta acaacaggag caacaaagga gctgtgggca actgtgttac
      721 caccatggtg cataaccact acgcctcctc aaagaaggtg tctcctccca agagctccaa
      781 ccagacagcc ccctccctca acaatattgt gaaggcagca gctcgtgagg gcggtgaggg
      841 cagcgacttt gggaagcctc ggaagaactt ctccagtgtc agtcagtcca ctcggggcac
      901 caccggcctg ctgaggagga aggaggtgac tgaggaggaa gctgagaggt tcatccagca
      961 ggtaaaccag gccgcagtca ccatccaacg ctggtaccgc tgtcaggtac agaggcgccg
     1021 aacaggagca gcaagcctcg agcacctgct ggcatccaag cgagaggggc agaggcaacg
     1081 gttgggaagt gggaaccttc tggacctgca ccggcaggag gaagcagcaa ggaagaaggc
     1141 ccgggaggag aaggctcgcc aggccaggca ggcagccatt caggaactgc agcagaaacg
     1201 agcccagaaa gcacgggaag tggagcacag gccacctaag gagagaccag agaccagggc
     1261 actggagcag cctcgaccca cccaggagcc gccctccatg cccagcagcg tcacacaccc
     1321 caaggccaac aatgctggtg ccagcctcta ccccacaggc cccgcagacc cctgccctcc
     1381 tgcctctgaa tcattcccag agcgacagcc atctctagag gacaagccac aggatgccca
     1441 ttcccaggtt gaagccagag aggacttggc agcgttggcc tcgaccagga gcaagaccag
     1501 ggccagagca accctagatg atcttctgga cacgctgaag ctgctggagg aggagcctga
     1561 gccgctgctt caccccaagg cctaccgtca ggacagatac gcctggatgg atgaggagga
     1621 ggataccaac cccctgactg cagacaacct ggagaagttt gggaaactca gtgcagcccc
     1681 tggccccccc gacgacggga ccctactctc cgaggccaag ctgcagagca tcatgacctt
     1741 cctggacgag atggagaagt cagggcagga gcggcccgca ccctggcggg agagcctggt
     1801 gctagaggcg ggcccaaggt ccctggaact ggggtctgag ggaactacgt ccgtgatgcg
     1861 gctgaagctg gagctagagg agaagaaaca ggccatggtt ctgctgcaga gagctctggc
     1921 gcaacagcgg gacctcgcca ctcgccgtgt taaggagaca gagaaggagc tgagccggca
     1981 gctgcggcag cagaaggagc agtacgaggc caccatccag cggcacttgt ccttcattga
     2041 ccagctgatc gaagacaaga aagtccttag cgagaagtgt gaggcggtgg tggctgagct
     2101 gaagcagggg gaccagcggt gtcgggagcg tgtggcacag gtgcaggagc agcacgaact
     2161 ggagatcaag aaactcaaag aactcatgag cgccaccgag aaaatccggc gtgagaagtg
     2221 gattaacgag aaaacgaaaa agatcaagga aatcacagtc agaggtctag agcctgagat
     2281 ccagaaacta attgccaagc acaagcagga ggtgaggagg ctcaggggcc tgcatgaggc
     2341 tgagctgcaa cagcgcgagg agcaggccgc acagcgccac ctgcgtcagg cagaggagct
     2401 gcgggagcac ctggagcggg agagggaggc gctgggccag caagagcggg agcgagccca
     2461 gcagaggttg gagcagcacc tggagcagga acagcgggcc ttggagcagc agcggcgacg
     2521 gctctacact gaggtggccg aggagaagga gcgactgggc cagcaggcag ccaggcagcg
     2581 ggtggagctg gaggagctga ggcagcagct ggaggagagc agtgcagccc tcactcgagc
     2641 cctgagagcc gagttcgaga ggagccgaga ggagcaggag cggaggcacc agatggagct
     2701 gaaggccctg aaggaccagc tggaagctga gagacaggcg tgggtggcca gctgtgccaa
     2761 gaaggaggaa gcatggctgc tgaccaggga acgtgagctg aaggaggaga tccgaaaagg
     2821 ccgagaccaa gagattgagt tggtcatcca ccggctggag gctgatatga ccttggctaa
     2881 ggaggagagc gagagagcag ccgagaaccg tgtgaaacgt gtgcgtgaca agtatgagac
     2941 cgagctctcg gagctggagc agtcggagcg caagcttcag gagcggtgca cagagctgaa
     3001 aggacgtctg ggagaggctg aaggggagaa ggagcggctg cagtctctac tacgccagaa
     3061 agagaaggaa ctggatgacc tgcgggtggt aaacacacag atgtgcagtg agcgggccag
     3121 cctggcccaa gtggtccgac aggagtttgc tgagcagctg gcagcctccc aggaggagac
     3181 ccagagggtg aaggcagagc tcgcagagct gcgggcccgt cagcagatgg agctagatga
     3241 ggtgcatcgg agggtgaaga cggctctagc gaggaaggag gcagccgtga acagtctccg
     3301 gaaacagcac gaggctgccg agaagcgggc ggaccacctg gaggagctgc tggagcaaca
     3361 caaagggcca tctttgagtt ccaagtgaca tctcccttgg gacgacaagc caagcctgag
     3421 gcagacgctc aggcctgtgg ctggtgtcca ggtcatgctc caagacacag ggctgagggt
     3481 aggacaacag ctggtgtgtg agaggcaccg tggagcccac tgcccaggac actactgtct
     3541 gcaagcctgc agctgttctg tagtaaaatg gttaggtggc ttttttaact gtttcatgtc
//
