LOCUS       NM_145082               4919 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus centrosomal protein 104 (Cep104), mRNA.
ACCESSION   NM_145082 XM_001076921 XM_575968
VERSION     NM_145082.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4919)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   2  (bases 1 to 4919)
  AUTHORS   Babcock,K.K., Chen,X., Eggeman,K.T., Kumar,K.N., Decedue,C.J. and
            Michaelis,E.K.
  TITLE     A synaptic membrane glycine-, glutamate- and
            thienylcyclohexylpiperidine-binding protein: isolation and
            immunochemical characterization
  JOURNAL   Neurochem Int 29 (5), 507-519 (1996)
   PUBMED   8939461
REFERENCE   3  (bases 1 to 4919)
  AUTHORS   Kumar,K.N., Babcock,K.K., Johnson,P.S., Chen,X., Ahmad,M. and
            Michaelis,E.K.
  TITLE     Cloning of the cDNA for a brain glycine-, glutamate- and
            thienylcyclohexylpiperidine-binding protein
  JOURNAL   Biochem Biophys Res Commun 216 (1), 390-398 (1995)
   PUBMED   7488117
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA924538.1, BI289406.1, CB544954.1, JAXUCZ010000005.1, U53513.1,
            CV797293.1, CB792008.1, CO390283.1, FM108776.1, DV722335.1 and
            CK843167.1.
            
            On or before May 22, 2010 this sequence version replaced
            XM_575968.4, XM_001076921.2, NM_145082.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data from several strains because no single
            transcript was available for the full length of the gene. The
            extent of this transcript is supported by transcript alignments and
            orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.1321335.1,
                                           SRR26360186.630141.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-475               AA924538.1         1-475
            476-692             BI289406.1         20-236              c
            693-990             CB544954.1         152-449
            991-1149            JAXUCZ010000005.1  169826845-169827003
            1150-1365           JAXUCZ010000005.1  169827869-169828084
            1366-1560           JAXUCZ010000005.1  169829585-169829779
            1561-2986           U53513.1           138-1563
            2987-3453           CV797293.1         16-482              c
            3454-3654           CB792008.1         236-436
            3655-4163           CO390283.1         141-649
            4164-4167           FM108776.1         454-457
            4168-4529           DV722335.1         1-362
            4530-4919           CK843167.1         1-390               c
FEATURES             Location/Qualifiers
     source          1..4919
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..4919
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /note="centrosomal protein 104"
                     /db_xref="GeneID:246295"
                     /db_xref="RGD:708505"
     exon            1..208
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            209..359
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     CDS             247..3021
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /note="glycine-, glutamate-,
                     thienylcyclohexylpiperidine-binding protein; gly-, L-Glu
                     and TCP-binding protein; glycine-, glutamate- and
                     thienylcyclohexylpiperidine-binding protein"
                     /codon_start=1
                     /product="centrosomal protein of 104 kDa"
                     /protein_id="NP_659550.2"
                     /db_xref="GeneID:246295"
                     /db_xref="RGD:708505"
                     /translation="MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPKFCQFPQ
                     EIVLQMVERCRIRKLQLLAHQYMISSKVEFYISESLPEYLVPYQAERFRRLGYVSLCD
                     NEKTGCKARELKSVYVDAVGQFLKLIFHQNHANKYNVYNQVALVAINIIGDPADLGDE
                     SNTTCREKLIDHYLGHSPHNPEDPALDGTFAGRSDYISPLDDLAFDMYQDPEVAQIIR
                     RLDERKREAAKKERYDHAKKLKQAIADLQKVGERLGRYEVEKRRAVEKEDYDLAKEKK
                     QQMARYRAQVYEQLELHGLLQGEPEMQRPFALPLQPLASPSSPQHWKAVSSLPRTEEL
                     AAEDTCAGPILQEKPLASSPRHSAVDRSPPAAGPAPRSHVEALPYDERPLPVTRKQLE
                     EPSAEPEVREADSDVRRRGVSAEPEPLTEKALREASSAIDTLGEALVAGAYSKMWSCR
                     EDALLALYKRLMEMPVGTQKGFVKNMLRASVFLIRRAIKDIVTSVFQASLKLLKMIIT
                     QYIPKHKLGKLDTTYCVERAIPLLLARTGDSSARLRVMALNFIQEMALFKEVRSLQLI
                     PSYLVQPLKTNASVHLAMSQVDLLARLLRDLGTEGSGFTVDNVMKFAVSALEHRVYEV
                     RETAVRIILDMYRQHPALTLEHLPPDDSTTRRNLLYKAIFEGFAKIDGRPTEAEGKTQ
                     KRVVTKEAEKQKKEETKALQGLSAAPRETQAGVQEKENEAVKLKNQDPQGRKAAPPDT
                     PEIPDNHYLDNLCIFCGERNESFTEEGLDLHYWKHCLMLTRCDHCRQVVEISSLTEHL
                     LTECDKRDGFGKCPRCSEAVPKEELPRHIKTKECNPAKSEKVANRCPLCHENFAPGEE
                     AWKVHLMGSAGCTMNLRKTHILCKAPAPQQGKGPMASKSGTSAPKVGSKIPTPKGGLS
                     KSSSRTHTRR"
     exon            360..533
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            534..672
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            673..735
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            736..821
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            822..990
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1149
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1365
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1560
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1728
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1902
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2079
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2286
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2394
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2431
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..2498
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2499..2607
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2608..2746
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2814
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2815..2905
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..4902
                     /gene="Cep104"
                     /gene_synonym="GlyBP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcggt cttcagcagg cacccggggc ggagtctccc tgacacctgg ccttggaggg
       61 acgcggctag tgcctgctcc aggcctctcg gccgcgcagt cagccttagt gtgcggaatc
      121 aggttcgagc ttcgccttgt cctcttctgc atgcgttact gaacaggacc agttgccacg
      181 agactgaagg ctgtaactct ggccccggaa gtcttccctg ctctctggac agcaagtgtg
      241 tgcagaatgc cccacaagat tggatttgta gtggtcagct cctctggaca tgaagatggc
      301 ttcagcgccc gggaactaat gatccacgca ccaactgtca gtgggtggag gtcaccaaaa
      361 ttctgccagt ttccacaaga gatcgttctg cagatggtgg agcggtgcag aataaggaag
      421 ctgcagctgc tggctcacca gtacatgatc tccagcaaag tcgagttcta catcagtgag
      481 agcctgcccg agtacttggt gccataccaa gcagagcgct tccgcagact gggctatgtc
      541 tccctctgtg acaatgaaaa gacaggctgc aaagcccggg aactcaagtc tgtttatgtg
      601 gacgctgtgg ggcagtttct taaactcatt tttcaccaaa accacgccaa caagtacaac
      661 gtatataatc aggtggcttt ggttgcaata aatatcattg gagaccctgc agatttgggc
      721 gatgaaagca atactacctg tagggagaag ctgatcgacc actacctggg ccacagtccc
      781 cacaatcctg aggacccagc cctagatgga acttttgctg ggagatctga ttatatctct
      841 ccactcgatg acttggcgtt tgacatgtac caagaccctg aagtcgccca gatcatccgc
      901 aggctggatg aaaggaagcg ggaagcagcc aagaaggagc gctatgacca tgcaaagaaa
      961 ctgaagcaag ccatcgctga cttgcagaag gtcggtgagc gcctcgggcg ctatgaggtg
     1021 gagaagcgcc gtgcggtgga gaaggaagac tatgacctgg ccaaggagaa gaaacagcag
     1081 atggctcgct accgtgccca ggtgtacgag cagctggagc tacatggcct tctgcagggc
     1141 gagccagaga tgcagagacc gttcgccctg cccctccagc cccttgcatc tcccagcagt
     1201 ccccagcact ggaaggcagt gtcctcactc cctcgcacag aagagctggc agctgaagac
     1261 acatgtgctg gccccatcct ccaggagaag cccttggcat cttctcctcg gcattcagca
     1321 gtggatcggt ccccacctgc tgcaggccct gccccaagga gccatgtgga agccctgccc
     1381 tatgatgaac ggcctcttcc tgtcactcgc aagcagttgg aggaaccatc tgcagagcca
     1441 gaagtgagag aggcagacag tgatgtccgg agacggggtg tctcagcgga gccagagccc
     1501 ttgacagaga aggctttgag agaagccagc tctgccatcg acaccttagg cgaagccttg
     1561 gtggctgggg cctattctaa gatgtggtcc tgtcgagaag atgcactgct ggcattgtac
     1621 aagaggctga tggagatgcc tgttggaacc cagaagggat ttgtgaaaaa catgctcaga
     1681 gcatctgtct ttctcatcag aagagccata aaggacattg taacctcagt ctttcaggct
     1741 tcactgaaac tgctgaagat gataattaca cagtatattc ccaagcacaa gctgggcaaa
     1801 cttgacacaa cgtactgtgt ggagagagct atcccccttt tacttgccag aactggagac
     1861 tcctctgccc gcctccgtgt catggccttg aatttcatcc aggaaatggc cttgtttaag
     1921 gaggtgaggt ctctccagct cattccgtct tacttggtgc agccgctgaa gaccaatgct
     1981 tccgttcatc tggcaatgag ccaggtggac ctcctggccc ggctgctgag agacctgggc
     2041 actgagggct caggcttcac cgtggacaat gtgatgaagt ttgcagtgag cgccctggag
     2101 cacagggtat atgaggtgcg agagacagca gtcagaatca ttctggacat gtacagacag
     2161 cacccagccc tcaccctgga gcaccttcct ccagacgaca gcaccacacg caggaacctt
     2221 ctctacaaag ccatatttga ggggtttgct aagatagatg gcaggccgac cgaggctgaa
     2281 ggcaagaccc agaaaagagt agtcacaaaa gaagcagaaa aacaaaagaa agaagagacg
     2341 aaggctctac agggcctgtc agcagcacca agagagaccc aggctggagt ccaggagaag
     2401 gagaatgagg ctgtgaagct caagaatcaa gaccctcaag gaaggaaagc tgccccacct
     2461 gacactccag aaatcccaga taaccactat ttggataatc tgtgcatctt ttgtggggag
     2521 aggaatgagt ccttcacaga agagggcctg gacctccact actggaaaca ctgcctcatg
     2581 ctgaccagat gcgaccactg caggcaggtg gttgagatat ccagcctgac tgaacacctg
     2641 ctgacagagt gtgacaaaag ggacgggttt gggaagtgcc cccgctgcag tgaggctgtc
     2701 cccaaggagg agcttcctag gcacatcaaa actaaggaat gcaaccctgc caagtcggag
     2761 aaggtggcaa accgctgtcc cctgtgtcat gagaactttg ctcctggaga agaggcatgg
     2821 aaggttcatc tgatgggctc tgctggctgc acaatgaacc tgcgcaagac acacattctc
     2881 tgcaaggctc cagccccgca gcaagggaaa ggcccaatgg cgtcgaagtc aggcacctca
     2941 gcacccaagg ttggaagcaa gatccccacc ccaaagggag gcctcagtaa gagttccagc
     3001 aggacacaca caagacggtg acagagtttt cagttctgtc tccgccaggg gctgtgcaag
     3061 gttccctgtt ctaagccagt atgttggcat ggtgatgcag ggctctgtgc ccaccgtccc
     3121 ttggcctctt gtgtcctagt gtctactgtc acaagaacag tacatgatat gaccaaagag
     3181 ccctttccaa tgtggccgca gttctgggcc ctctgtcagt gctcagaatg ccacaggcac
     3241 agcacccacc cccttactac tgagaagacg caccccagac ttggagctca ctggtgtgag
     3301 cacacattgg gctttgcaca gggctaagtt ggctttggtg gccctagaag actacagcaa
     3361 gccacactgg gcctgctgtg ctgtctctcg tggtcctgtc tgccaggttg tcacactata
     3421 tacagcgaca aacaataaag gaaatcaagc aaagacagcc actctaagag caggtccctc
     3481 ctacgcacac agcccgatgc tcactgtgta cctgtccctg tggcccccct gacagccctg
     3541 ccttgatgcc ttccctcggt gggtgcagag ccctgaatga atggatgctg gatgatgtgt
     3601 cctggttacc ctacatgcac ctgaccacaa cccacctgca agcctcagtt ttccttatgg
     3661 caaaattaat gccttccaca tttgcctagc ccacaaagat gtcacacata ccttgctggc
     3721 ccagagctct gtcacatccc gtgatgtaac tgaacccaca ttcccaaatc cttcatagtg
     3781 cccgctcaca agtgcttcac tgatcagtga cacagacctc agaacacagc tgtcagcggc
     3841 tcacccgtgt cctcatccct cctgtcaccg ttcctgcttc ctgaggaact gtccctttga
     3901 aatgtctagg attgagaaca tgaatattat aaaattaggg catatttctt taaaattccc
     3961 aaccatgtga accaagctcc ataaagatgt gtgtgtgccc gagcagcacc ctgggcgcta
     4021 acctcgtgga ctcacccctg cttttggcaa atggctccca ctgtgcttgg ctcagagtat
     4081 caagtggaac aggatctatc aagaggaggc tcctgtcaga gcagaggcct ttagtgtcaa
     4141 gaaaacaggg caggactaag aaagcaaagc tgggcgccaa gggatgataa ggtggccctt
     4201 caggtcagag atgctggcat tgtttcctaa cctgccttaa agtacagacg ataatggaga
     4261 gttaacctca gaactagaca gaagtacata cctgtaatgt ttctatctgt tgtaaccctg
     4321 agatgctgta aatcccttca tttttaaccc agcatggtgg ctcacccctg tactcctagc
     4381 acttgggagg ctgaagttag aagctcagag ggaagcctgg gctacagagt gagaccggct
     4441 cagaataaga cagagcaaca aagagtactt catttttagc tctcatgttt tgcctgttac
     4501 agaatcatga gtttctgcag aggtgactgg caggcagtat tggcagccac aaagctccac
     4561 atcactgtgc ttgattcagg gaaggagcta cgtaccccca gcccttcata atatctaagt
     4621 ggatcactcc tcaaaccttc acgtatgcta cattgtggat atttaatatt tatttatatt
     4681 attttcataa aagattctac ttaatttaaa agaattgtgt catatctgat actaaaatac
     4741 aaatgtaaat acctctaatg aaaatttgca actttttaat gttttaacat agttttctat
     4801 ttgtctttat ttcaggtata gaataatata tttttattgt tgctgtttga gggtttatgt
     4861 gctaatttgc cttgtgtaca ctaataccgt aaagatcact caaaaaaaaa aaaaaaaaa
//
