LOCUS       NM_001244761            1751 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus centromere protein L (Cenpl), transcript variant
            2, mRNA.
ACCESSION   NM_001244761
VERSION     NM_001244761.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1751)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
REFERENCE   2  (bases 1 to 1751)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC089893.1.
            
            Transcript Variant: This variant (2) lacks an alternate exon, which
            results in translation initiation at a downstream start codon,
            compared to variant 1. The encoded protein (isoform 2) is shorter
            than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089893.1, SRR8487231.116855.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1751              BC089893.1         1-1751
FEATURES             Location/Qualifiers
     source          1..1751
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q22"
     gene            1..1751
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /note="centromere protein L"
                     /db_xref="GeneID:289150"
                     /db_xref="RGD:1311868"
     exon            1..408
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /inference="alignment:Splign:2.1.0"
     exon            409..582
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /inference="alignment:Splign:2.1.0"
     CDS             412..1449
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /note="isoform 2 is encoded by transcript variant 2;
                     CENP-L"
                     /codon_start=1
                     /product="centromere protein L isoform 2"
                     /protein_id="NP_001231690.1"
                     /db_xref="GeneID:289150"
                     /db_xref="RGD:1311868"
                     /translation="MDTYDSQGPTSRRRTSNLKDYFVSATPLQKRLKLARRQSSVFPS
                     PSRRKIPQCSQLQEDIDPQKVAFLLHKQWTVYSLTPLYKFSYSNLKDYSRLLSAFIAA
                     EKQKGLAVEVGEDFNIKVIFSTLLGVKGTQRDPEAFLVQIRSESQSSREHRQDKVLWT
                     GWFCCVFGENLQETVSEDFTCLPLFLAHGAESNTSLIGGWFQKTFDCCFSPLAISAFN
                     LSWMAAMWTACKMDHYMATTEFFWSVPCSPQSLDISYAIHPEDAKALWDSVHKTPGEV
                     TQEEVDLFMNCLYSHFHRHFRIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVLA
                     YMTELAIFQIE"
     exon            583..834
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /inference="alignment:Splign:2.1.0"
     exon            835..1377
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1725
                     /gene="Cenpl"
                     /gene_synonym="RGD1311868"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagtgtgga gttgcgcctt tgcgaacgga ggtttcaagc ctacttatgg tctcaggaga
       61 gctccggaga agggtcttgg ggactcccgg tctttcgtgg gccgacgcca gcctccgaag
      121 actgaaggtc gcagagccgg gctgcttggg aagcgaacct gtctctccca gggtgaagtt
      181 gctggtgctg ctcgcgcccg agggaagcta ggttcccttc agggatcctt atgtctcttc
      241 tgaacccacc tggcattgct tcggctctct cttagccgtc atttcggccg ctttctttct
      301 tcttcttaaa aagccaaaac ctttcgtctc gacgtggtct tggagccaaa cttgaagaat
      361 gattcgtgaa tccggaatgg acgacagtgt cattacgaca taattttgac catggatact
      421 tatgattctc aaggaccaac ttctagacga aggacctcaa atcttaagga ctactttgtg
      481 agtgccaccc ctctgcagaa acgactgaag ttggccagga gacagagttc agtttttccc
      541 agtccatctc gaaggaaaat tccccagtgt tcacagttgc aggaagatat cgatcctcag
      601 aaggttgcat ttctcctcca caaacagtgg actgtatata gtttaactcc cctgtataaa
      661 ttctcctatt ctaatctcaa agactattct agacttctaa gtgcatttat tgctgccgaa
      721 aagcaaaaag gacttgctgt ggaagtggga gaagacttca atatcaaagt gattttctct
      781 actcttcttg gagtgaaagg gacgcaaagg gaccctgaag catttcttgt ccagattcgt
      841 tcagaatccc agtcatcacg tgaacacaga caagataaag tgttgtggac cggttggttc
      901 tgttgtgtat ttggagagaa ccttcaggag actgtctcag aagatttcac ctgtctaccc
      961 ttattccttg cacatggagc ggaatccaac acatccctaa tcggaggctg gtttcagaaa
     1021 acttttgact gttgctttag tcctttagca atcagtgcat ttaatctttc ctggatggct
     1081 gctatgtgga ctgcatgcaa aatggaccat tacatggcta ctactgaatt cttttggtct
     1141 gtgccctgta gcccacagag cttagatatt tcttatgcca tacatccaga ggatgcaaaa
     1201 gctttatggg acagtgtcca caaaacacct ggggaagtta cccaggagga ggtcgactta
     1261 tttatgaact gcctttattc acatttccat aggcatttca gaattcactt atcagccaca
     1321 agattggttc gcgtctcaac gtctgtagct tcggcacaca cggatgggaa aataaagatc
     1381 ctgtgtcata aataccttat tggtgtgttg gcatatatga cggaactggc tatttttcaa
     1441 attgaatgaa ttcttgtatg gactaattga tgcattgtaa acccttttga tcatttgctg
     1501 aattgctatg ctgagtggga cagtagaaga aatggagcac ttgttttctc aggatgcctt
     1561 cggagttgcc caggtggatc tggaacccag tagtggtagt gggtgagctg cattcctggg
     1621 cttgtgtacc catcatgtca ctgtggctgt gtcatgttat aaaagatggt gaattgttaa
     1681 tataaaagga tccaatttag tcaaataaac ttatctaaac tctgaaaaaa aaaaaaaaaa
     1741 aaaaaaaaaa a
//
