LOCUS       NP_037087                745 aa            linear   ROD 27-APR-2025
DEFINITION  centromere protein I [Rattus norvegicus].
ACCESSION   NP_037087
VERSION     NP_037087.1
DBSOURCE    REFSEQ: accession NM_012955.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 745)
  AUTHORS   Mukhopadhyay,D., Arnaoutov,A. and Dasso,M.
  TITLE     The SUMO protease SENP6 is essential for inner kinetochore assembly
  JOURNAL   J Cell Biol 188 (5), 681-692 (2010)
   PUBMED   20212317
REFERENCE   2  (residues 1 to 745)
  AUTHORS   Slegtenhorst-Eegdeman,K.E., Post,M., Baarends,W.M., Themmen,A.P.
            and Grootegoed,J.A.
  TITLE     Regulation of gene expression in Sertoli cells by
            follicle-stimulating hormone (FSH): cloning and characterization of
            LRPR1, a primary response gene encoding a leucine-rich protein
  JOURNAL   Mol Cell Endocrinol 108 (1-2), 115-124 (1995)
   PUBMED   7758824
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X90355.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X90355.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132302, SAMN06680444
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..745
                     /organism="Rattus norvegicus"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq32"
     Protein         1..745
                     /product="centromere protein I"
                     /note="CENP-I; FSH primary response protein 1;
                     leucine-rich primary response protein 1;
                     follicle-stimulating hormone primary response protein; FSH
                     primary response 1; Follicle stimulating hormone primary
                     response gene 1 (Leucine - rich primary resonse gene 1)"
                     /calculated_mol_wt=85520
     Region          1..58
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q63517.1)"
     Region          8..515
                     /region_name="CENP-I"
                     /note="Mis6; pfam07778"
                     /db_xref="CDD:429654"
     Site            order(138,142,146,176..177,180,183..184,187,190..193,
                     212..214,218,221,224..229,251)
                     /site_type="other"
                     /note="pentamer interface [polypeptide binding]"
                     /db_xref="CDD:439352"
     CDS             1..745
                     /gene="Cenpi"
                     /gene_synonym="Fshprh1; LRPR1; RNALRP"
                     /coded_by="NM_012955.1:206..2443"
                     /db_xref="GeneID:25448"
                     /db_xref="RGD:2631"
ORIGIN      
        1 matprltrns qqqnrisqgs nsrqttlldw kvkdkagnsk svleesssle dsnhaddqte
       61 dalqtaveyf qkgpkkasls kdsvlekhlk tvenvawnng lapeaidill nvalsgkfgn
      121 alstrilkcm ipethiseds vvkavswlcv gkcsgntkvl fyrwlvamfd fidhkkqins
      181 lygfffvslq ddtlcpyvch llylltkken vkpfrarkll dlqakmgmqp hlqallslyk
      241 ffaptlisvs lpvrkkiffn nsknlwtpal lavklrnqgi fpeplklqlg ptsgrslkrk
      301 wnyhsvipav nsakkecrek mslfdylsnd rslpveqlqs fpqllenihc lelpsqmssv
      361 lnsslllhyv ncvkdesill rlsywlsqtl qeecvwynmn dyqqekefin fldmvirvqc
      421 flqegfysce aflykslplw dgfscrsqfl kllawipfss fseikpllld hlaplfftss
      481 iyfkcsllqc lkdllqnwll wlsteaqvqp mtdsplettl ggsmdsvsql ieyigwlsmv
      541 airlessstl lvhfildfye kvcdiyinyd lplvvlfppv vfhsaflsld atilnqlcyi
      601 myryrdnlta akkkdlvqka ksefsisski ckefnyylta lvhclwssrp fetgvyidpq
      661 iientgetqy khnlnfvhhp cllnyaasfl lqespeempv hlssirgkkw nwyldhlyse
      721 gfqglnlfik ssidhssvsk teknt
//
