LOCUS       NM_001399529            1230 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus centromere protein H (Cenph), transcript variant
            1, mRNA.
ACCESSION   NM_001399529 XM_008760701
VERSION     NM_001399529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1230)
  AUTHORS   Mukhopadhyay,D., Arnaoutov,A. and Dasso,M.
  TITLE     The SUMO protease SENP6 is essential for inner kinetochore assembly
  JOURNAL   J Cell Biol 188 (5), 681-692 (2010)
   PUBMED   20212317
REFERENCE   2  (bases 1 to 1230)
  AUTHORS   Sugata,N., Li,S., Earnshaw,W.C., Yen,T.J., Yoda,K., Masumoto,H.,
            Munekata,E., Warburton,P.E. and Todokoro,K.
  TITLE     Human CENP-H multimers colocalize with CENP-A and CENP-C at active
            centromere--kinetochore complexes
  JOURNAL   Hum Mol Genet 9 (19), 2919-2926 (2000)
   PUBMED   11092768
REFERENCE   3  (bases 1 to 1230)
  AUTHORS   Sugata,N., Munekata,E. and Todokoro,K.
  TITLE     Characterization of a novel kinetochore protein, CENP-H
  JOURNAL   J Biol Chem 274 (39), 27343-27346 (1999)
   PUBMED   10488063
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jan 10, 2022 this sequence version replaced XM_008760701.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV780426.1, FN803416.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               JAXUCZ010000002.1  33644089-33644242   c
            155-210             JAXUCZ010000002.1  33641309-33641364   c
            211-259             JAXUCZ010000002.1  33640202-33640250   c
            260-334             JAXUCZ010000002.1  33639754-33639828   c
            335-391             JAXUCZ010000002.1  33636919-33636975   c
            392-455             JAXUCZ010000002.1  33634603-33634666   c
            456-507             JAXUCZ010000002.1  33633994-33634045   c
            508-671             JAXUCZ010000002.1  33632689-33632852   c
            672-1230            JAXUCZ010000002.1  33630738-33631296   c
FEATURES             Location/Qualifiers
     source          1..1230
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..1230
                     /gene="Cenph"
                     /note="centromere protein H"
                     /db_xref="GeneID:681185"
                     /db_xref="RGD:1583506"
     exon            1..154
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..764
                     /gene="Cenph"
                     /note="isoform 1 is encoded by transcript variant 1;
                     centromere autoantigen H"
                     /codon_start=1
                     /product="centromere protein H isoform 1"
                     /protein_id="NP_001386458.1"
                     /db_xref="GeneID:681185"
                     /db_xref="RGD:1583506"
                     /translation="MEPLRERPVAGAEACGEERGPQASEERIMDRISLLLRLRAQTKQ
                     QLLEYKSVIDANEEKTPEQIMQEKQIEVKIEDLENEIEDVKSNFEVKSLALSRMKLSA
                     ALQNNLENMGPESSLLTDDMKHVMQLQKLIMKSQEESKELEKKLLDVRKKRLQLKQAS
                     RSKLLEIQTERNKQKEDVDKMENSEVVKAMKDKLQLEIKITTVIQHAFQGLILGSKTN
                     WAEDPTLRELVLQLEKNLTTL"
     exon            155..210
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            211..259
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            260..334
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            335..391
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            392..455
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            456..507
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            508..671
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
     exon            672..1230
                     /gene="Cenph"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caatttcgtg gcgggaagaa ctgctgcggt gtttctcctc tgcgatggag ccgctgcggg
       61 agaggcctgt ggccggggct gaggcctgcg gagaggagcg gggtccgcag gcctcggagg
      121 agcggatcat ggaccgcatc agcctgctgc tcagactgag agcacagaca aaacaacagc
      181 tcttggagta taagtccgtg atcgacgcaa atgaagaaaa aactccagaa cagatcatgc
      241 aagaaaaaca aattgaagtt aaaattgaag acctggagaa tgaaatagaa gatgtaaaaa
      301 gtaattttga agtgaaaagt ctcgcactga gcaggatgaa actttcagct gcccttcaga
      361 ataacttgga gaacatgggc cctgagagta gtctgctcac tgatgacatg aagcacgtga
      421 tgcagctaca gaagttaata atgaagtccc aggaggagtc taaggaactg gagaaaaagc
      481 tgcttgatgt cagaaagaag agactacaac taaaacaagc ttcaagaagt aagcttttag
      541 aaatacaaac agagaggaac aaacagaaag aggatgtgga caagatggag aattctgaag
      601 tggtaaaggc catgaaagac aagctacagt tggagataaa gatcactact gtcattcaac
      661 atgcattcca gggccttatt ttggggagta aaaccaactg ggcagaggat cctacactca
      721 gagagcttgt gctgcagctg gagaagaatc tcactacact gtaataagac tctcaccttg
      781 gcattttaaa atgggttttg tggccaatct gtcattccag gatcagagtt catgggaaat
      841 gtaaatagtg tttttagaac ctttctctgc ttcagtgttt ggatttcgag ttgatgctat
      901 ggcacggaat cttttgtttt aaatgtgctc agtaaagtga ctggcatact ctgcaggagt
      961 gtgaacgtcg aggccttgga aagaggcccc tgctcatgcc accactgaat gtgcacatct
     1021 ttgcagacgt tttcctggct gtccctcaga atatgcttat gcatctgtgc acactggctt
     1081 gtcagccaaa aattagaaca gcgtccgaag ggtaacgttg tgtttgtgaa gtaaggttct
     1141 tacttttttc tccttctcta tttagcatgc attttacttt tataagttaa ggaataaaaa
     1201 gaataaacat tactgtctta ttaactaaaa
//
