LOCUS       NM_001399319            2794 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus centromere protein B (Cenpb), mRNA.
ACCESSION   NM_001399319 XM_006235055
VERSION     NM_001399319.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2794)
  AUTHORS   Amor-Dorado,J.C., Arias-Nunez,M.C., Miranda-Filloy,J.A.,
            Gonzalez-Juanatey,C., Llorca,J. and Gonzalez-Gay,M.A.
  TITLE     Audiovestibular manifestations in patients with limited systemic
            sclerosis and centromere protein-B (CENP-B) antibodies
  JOURNAL   Medicine (Baltimore) 87 (3), 131-141 (2008)
   PUBMED   18520322
REFERENCE   2  (bases 1 to 2794)
  AUTHORS   De La Fuente,R., Viveiros,M.M., Wigglesworth,K. and Eppig,J.J.
  TITLE     ATRX, a member of the SNF2 family of helicase/ATPases, is required
            for chromosome alignment and meiotic spindle organization in
            metaphase II stage mouse oocytes
  JOURNAL   Dev Biol 272 (1), 1-14 (2004)
   PUBMED   15242786
REFERENCE   3  (bases 1 to 2794)
  AUTHORS   Van Hooser,A.A., Ouspenski,I.I., Gregson,H.C., Starr,D.A.,
            Yen,T.J., Goldberg,M.L., Yokomori,K., Earnshaw,W.C., Sullivan,K.F.
            and Brinkley,B.R.
  TITLE     Specification of kinetochore-forming chromatin by the histone H3
            variant CENP-A
  JOURNAL   J Cell Sci 114 (Pt 19), 3529-3542 (2001)
   PUBMED   11682612
REFERENCE   4  (bases 1 to 2794)
  AUTHORS   Uren,A.G., Wong,L., Pakusch,M., Fowler,K.J., Burrows,F.J.,
            Vaux,D.L. and Choo,K.H.
  TITLE     Survivin and the inner centromere protein INCENP show similar
            cell-cycle localization and gene knockout phenotype
  JOURNAL   Curr Biol 10 (21), 1319-1328 (2000)
   PUBMED   11084331
REFERENCE   5  (bases 1 to 2794)
  AUTHORS   Onozuka,Y., Shibata,M., Yonezawa,H., Terauti,K., Miyachi,K. and
            Ueno,Y.
  TITLE     [Clinical significance of anti-centromere antibody and anti-CENP-B
            antibody in sera of patients with primary biliary cirrhosis]
  JOURNAL   Rinsho Byori 44 (9), 877-882 (1996)
   PUBMED   8911074
REFERENCE   6  (bases 1 to 2794)
  AUTHORS   Yen,T.J., Compton,D.A., Wise,D., Zinkowski,R.P., Brinkley,B.R.,
            Earnshaw,W.C. and Cleveland,D.W.
  TITLE     CENP-E, a novel human centromere-associated protein required for
            progression from metaphase to anaphase
  JOURNAL   EMBO J 10 (5), 1245-1254 (1991)
   PUBMED   2022189
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 6, 2022 this sequence version replaced XM_006235055.4.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR22582419.2187016.1,
                                        SRR22582424.283440.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2794              JAXUCZ010000003.1  138850003-138852796 c
FEATURES             Location/Qualifiers
     source          1..2794
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..2794
                     /gene="Cenpb"
                     /note="centromere protein B"
                     /db_xref="GeneID:362217"
                     /db_xref="RGD:1304794"
     exon            1..2794
                     /gene="Cenpb"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1997
                     /gene="Cenpb"
                     /note="centromere autoantigen B"
                     /codon_start=1
                     /product="major centromere autoantigen B"
                     /protein_id="NP_001386248.1"
                     /db_xref="GeneID:362217"
                     /db_xref="RGD:1304794"
                     /translation="MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLST
                     ILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKE
                     KALRIAEELGMDDFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATV
                     PSEGSGGSTPSWRTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPA
                     RQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQGGLPCDYTANSKGGVTTQALAK
                     YLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVK
                     GHYRQAMLLKAMAALEGQDPSGLQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGG
                     LNATITTSFKSEGEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEEEGGEGEEVGEEEE
                     EVEEEGEVDDSDEEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQEEAQCPTLHFLE
                     GGEDSDSDSDEEEEDEEEDEEDEEDEDDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFP
                     IDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS"
ORIGIN      
        1 gctgggcacg tcctgccgcc cgcgcctccc gcgccgctcg ccaccgcccg ccgccgcccc
       61 gcgagccgct ttgtctcggg cggggcgcgc ggagaggccg ccaggtgccc cccgccgcgg
      121 gcccgggccc cccgccccgg ggcggcgacg gcggtgccgg gccccggggc ggagggcgcg
      181 ccgggatggg ccccaagcgg cggcagctga cgttccggga gaagtcgcgg atcatccagg
      241 aggtggagga gaacccggac ctacgcaagg gcgagattgc gcggcgcttc aacatcccgc
      301 cgtccacgct gagcaccatc ctgaaaaaca agcgcgccat cctggcgtcg gagcgcaagt
      361 acggagtggc ctccacctgc cgcaagacca acaagctgtc cccgtacgac aagctggagg
      421 ggcttctcat cgcttggttc cagcagatcc gcgccgccgg cctgccggtc aagggcatca
      481 tcctgaaaga gaaggcgctg cggatagcgg aggagctggg catggacgac ttcactgctt
      541 ccaacggctg gctggatcgc ttccgcaggc gccacggcgt agtggcctgc agcggcgtga
      601 cccgttcccg ggcgcgaagc tctgcccctc gggccccagc ggcacctgct ggcccagcca
      661 cggtgccctc ggagggcagt ggtgggagca cacccagctg gcgcactcgg gaggagcagc
      721 cgccgtcggt ggctgagggc tacgcctcgc aggacgtgtt cagcgccacc gagaccagtc
      781 tgtggtacga ctttctgtcg gaccaggcct cagggctctg gggaggtgat ggaccggcgc
      841 gccaggccac ccagcgcctt agcgttttgc tatgcgccaa tgccgatggc agcgagaagc
      901 ttcctccact ggtcgcaggc aagtctgcca agccccgtgc aggccaaggt ggtctgccct
      961 gtgactacac tgccaactcg aagggtggag tcaccaccca ggcgctggcc aagtacttga
     1021 aagctctgga cactcgaatg gctgcagaat ctcgtcgggt ccttctgctg gctggccgtc
     1081 tggctgctca gtccttggac acctcgggcc tgcggcatgt gcagctggcc ttcttccctc
     1141 ctggcaccgt gcatccattg gagcgaggag tagtccaaca ggtgaagggc cactaccgac
     1201 aggccatgtt gctcaaggcc atggcagcac tcgagggcca ggatccctca ggcttgcaac
     1261 tgggcctagt ggaggccctg cactttgtgg ctgcggcctg gcaggcagtg gagccctcgg
     1321 acatagcaac ttgctttcgt gaggctggtt ttggaggtgg ccttaatgcc actatcacca
     1381 cttccttcaa gagtgaggga gaggaagagg aggaggagga agaagaggag gaggaggaag
     1441 aagaggaggg tgaaggggaa gaggaggagg aagaggaaga agaaggggag gaggaagaag
     1501 gaggggaagg agaggaggta ggagaagaag aggaggaggt agaagaggag ggtgaggttg
     1561 atgatagtga tgaagaggag gaggaagaaa gctcctctga gggtttagag gctgaagact
     1621 gggcccaggg agtagtggag gccagcggtg gttttggggg ttatagtgtc caggaagagg
     1681 cccagtgccc caccctccat ttcctggaag gaggagaaga ctctgactca gacagtgatg
     1741 aagaggagga agatgaagag gaggatgagg aggatgaaga agatgaggat gatgatgagg
     1801 atggtgatga ggtccctgta cccagctttg gggaggccat ggcttacttt gccatggtca
     1861 agaggtacct gacctccttt cccattgatg accgagtgca gagtcacatc cttcatttgg
     1921 aacatgatct ggtccatgtg actaggaaga accatgccag gcaggcggga gttcggggtc
     1981 ttggacatca aagctgagct cctggacata gctgtgctcc agcccagatg ggtgtcacct
     2041 gcccaaggca gagaactctg ggcagctgct ggagatggct ggagaaaccc agggctttca
     2101 gtaatgcttc gccaggctcc aggctccagg ctccgagaca ggcccagggg ctgaggtccg
     2161 cctcactgct attgcctctt tctcagaatc ctctttcctc cccattagtc cctgggctca
     2221 gggcactgga tgggtgggga gctgtctggt gctaccacac catgccatca gtgggctaga
     2281 ctacagcagc agccagggtt gggtcctgga agctcttggc cagagagtgc ctctccccct
     2341 gccacccaac caggtctttg gtcgggggat cccaaagcca ttctggaaag ggctccagag
     2401 gaaggtctag cctaggcccc cacaaaacta gcagcccccc tcctgcatct ctaggttatc
     2461 taaagaagca cagtgtaact tagggcaggc tcctgagcct gcctctgcct gccttccacc
     2521 tccccagatc cctttctctg gcccagtctt tggcccttgg ttttctttcc agattggagg
     2581 tttccaagag gccctccagg ggagtgagtg acagcaggca cctccaatct gggtagctgc
     2641 aggcctttgt gcctcatcct ctgcaggccc ccatcctggg cagaggggcc tggggctggg
     2701 cccagagtcc agccatccag gtgctccttt cccagtttga attcaataaa tctgtccact
     2761 ccccttttgt gggagtgaat gttttaacag ccaa
//
