LOCUS       NM_001106711            1300 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus centromere protein A (Cenpa), mRNA.
ACCESSION   NM_001106711 XM_001069485 XM_216657
VERSION     NM_001106711.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Roulland,Y., Ouararhni,K., Naidenov,M., Ramos,L., Shuaib,M.,
            Syed,S.H., Lone,I.N., Boopathi,R., Fontaine,E., Papai,G.,
            Tachiwana,H., Gautier,T., Skoufias,D., Padmanabhan,K., Bednar,J.,
            Kurumizaka,H., Schultz,P., Angelov,D., Hamiche,A. and Dimitrov,S.
  TITLE     The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic
            Fidelity
  JOURNAL   Mol Cell 63 (4), 674-685 (2016)
   PUBMED   27499292
REFERENCE   2  (bases 1 to 1300)
  AUTHORS   Kim,I.S., Lee,M., Park,K.C., Jeon,Y., Park,J.H., Hwang,E.J.,
            Jeon,T.I., Ko,S., Lee,H., Baek,S.H. and Kim,K.I.
  TITLE     Roles of Mis18alpha in epigenetic regulation of centromeric
            chromatin and CENP-A loading
  JOURNAL   Mol Cell 46 (3), 260-273 (2012)
   PUBMED   22516971
REFERENCE   3  (bases 1 to 1300)
  AUTHORS   Liu,L., Li,Y., Zhang,S., Yu,D. and Zhu,M.
  TITLE     Hepatitis B virus X protein mutant upregulates CENP-A expression in
            hepatoma cells
  JOURNAL   Oncol Rep 27 (1), 168-173 (2012)
   PUBMED   21956590
REFERENCE   4  (bases 1 to 1300)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   5  (bases 1 to 1300)
  AUTHORS   Chan,Y.W., Fava,L.L., Uldschmid,A., Schmitz,M.H., Gerlich,D.W.,
            Nigg,E.A. and Santamaria,A.
  TITLE     Mitotic control of kinetochore-associated dynein and spindle
            orientation by human Spindly
  JOURNAL   J Cell Biol 185 (5), 859-874 (2009)
   PUBMED   19468067
REFERENCE   6  (bases 1 to 1300)
  AUTHORS   De La Fuente,R., Viveiros,M.M., Wigglesworth,K. and Eppig,J.J.
  TITLE     ATRX, a member of the SNF2 family of helicase/ATPases, is required
            for chromosome alignment and meiotic spindle organization in
            metaphase II stage mouse oocytes
  JOURNAL   Dev Biol 272 (1), 1-14 (2004)
   PUBMED   15242786
REFERENCE   7  (bases 1 to 1300)
  AUTHORS   Craig,J.M., Earle,E., Canham,P., Wong,L.H., Anderson,M. and
            Choo,K.H.
  TITLE     Analysis of mammalian proteins involved in chromatin modification
            reveals new metaphase centromeric proteins and distinct chromosomal
            distribution patterns
  JOURNAL   Hum Mol Genet 12 (23), 3109-3121 (2003)
   PUBMED   14519686
REFERENCE   8  (bases 1 to 1300)
  AUTHORS   Van Hooser,A.A., Ouspenski,I.I., Gregson,H.C., Starr,D.A.,
            Yen,T.J., Goldberg,M.L., Yokomori,K., Earnshaw,W.C., Sullivan,K.F.
            and Brinkley,B.R.
  TITLE     Specification of kinetochore-forming chromatin by the histone H3
            variant CENP-A
  JOURNAL   J Cell Sci 114 (Pt 19), 3529-3542 (2001)
   PUBMED   11682612
REFERENCE   9  (bases 1 to 1300)
  AUTHORS   Uren,A.G., Wong,L., Pakusch,M., Fowler,K.J., Burrows,F.J.,
            Vaux,D.L. and Choo,K.H.
  TITLE     Survivin and the inner centromere protein INCENP show similar
            cell-cycle localization and gene knockout phenotype
  JOURNAL   Curr Biol 10 (21), 1319-1328 (2000)
   PUBMED   11084331
REFERENCE   10 (bases 1 to 1300)
  AUTHORS   Muro,Y., Azuma,N., Onouchi,H., Kunimatsu,M., Tomita,Y., Sasaki,M.
            and Sugimoto,K.
  TITLE     Autoepitopes on autoantigen centromere protein-A (CENP-A) are
            restricted to the N-terminal region, which has no homology with
            histone H3
  JOURNAL   Clin Exp Immunol 120 (1), 218-223 (2000)
   PUBMED   10759786
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_216657.2, XM_001069485.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC166997.1, EV774954.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..1300
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /note="centromere protein A"
                     /db_xref="GeneID:298850"
                     /db_xref="RGD:1563607"
     exon            1..176
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..496
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /codon_start=1
                     /product="histone H3-like centromeric protein A"
                     /protein_id="NP_001100181.1"
                     /db_xref="GeneID:298850"
                     /db_xref="RGD:1563607"
                     /translation="MVGRRKPGTPRRRPSSPAPGPSQPATDSRRQSRTPTRRPSSPAP
                     GPSRRSSGVGPQALHRRRRFLWLKEIKNLQKSTDLLFRKKPFGLVVREICGKFSRGVD
                     LYWQAQALLALQEAAEAFLVHLFEDAYLLSLHAGRVTLFPKDVQLARRIRGIEGGLG"
     exon            177..283
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /inference="alignment:Splign:2.1.0"
     exon            284..361
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /inference="alignment:Splign:2.1.0"
     exon            362..512
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /inference="alignment:Splign:2.1.0"
     exon            513..1300
                     /gene="Cenpa"
                     /gene_synonym="RGD1563607"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accctcgcgt ccagccatgg tcgggcgccg caagccaggg accccgagga ggcgaccctc
       61 tagtccggcg cccggaccct ctcagccagc cacggactcg cgtcgccagt cgaggactcc
      121 gacgaggcgg ccctccagtc cggcgcccgg accctcgcga cggagctccg gagtaggccc
      181 tcaggcacta cacagaagac ggagattcct gtggcttaag gaaataaaga acctgcaaaa
      241 gagcacagac ctcttgttta ggaagaagcc tttcggcctc gtggtaagag aaatatgtgg
      301 gaaattcagc cgtggtgtgg atttatattg gcaagctcag gccttgttgg cccttcaaga
      361 ggcagcagaa gcgtttctcg ttcacctctt tgaggacgcc tatctcctct ccttacatgc
      421 tggccgagtc acgcttttcc ccaaagatgt gcagctagcc aggaggatcc gaggcattga
      481 gggaggactc ggctgagctg ccagtgcgat gtacaatacc tggaatcttt tggagctgca
      541 gccaaacagc agtgtctgag gcactgcctg gatattgctg gttttgagca gtggctacac
      601 gatgcccttt aagattgtgg cttttgcctg tgacagagga agaagaggcc atctgcctcg
      661 cccatggaca cgaatgagtg tttgcagacc aaaggtcaac ttggtttgtg aattgctcaa
      721 ccacattact gtttgcgggt ttcagaccca tgaggtctgc catgttatga ggggtattga
      781 tattttattc ttcctgtacc atgtgcatct tttatcctgt gtctttgtac tttttaaata
      841 taagggagaa gtttttgagt aaaatgttag aatctgttgt atggaaagcc ctggcagtcc
      901 cgcccgccat acaaatgtct gccttccaga ttgccctcac gctgcctgtc agcaaacatg
      961 gagcttttca aaacttaagt agcgttacat acacagtctt ctcttccttc ccttcaaggc
     1021 tgggacttga atccaatgtc ttatacatgc caaacatgga ctgtaatgtt gaactgcatc
     1081 cacagcctga aatatatagt ctttctggtt cctaccagta aattcctatg gaaaccatcc
     1141 agaaagtctc tcttagaagt agacagttta tccttagctg taaatcacat acaatgtatc
     1201 ataccagttt tgggatttta caacatgttt tccgtatttt ttacaggtta tctttagttt
     1261 atttgaggag aaataataaa aaaataattt cttagtgaga
//
