LOCUS       NM_001191977            4478 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus CECR2, histone acetyl-lysine reader (Cecr2),
            mRNA.
ACCESSION   NM_001191977 XM_575657
VERSION     NM_001191977.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4478)
  AUTHORS   Thompson,P.J., Norton,K.A., Niri,F.H., Dawe,C.E. and McDermid,H.E.
  TITLE     CECR2 is involved in spermatogenesis and forms a complex with SNF2H
            in the testis
  JOURNAL   J Mol Biol 415 (5), 793-806 (2012)
   PUBMED   22154806
REFERENCE   2  (bases 1 to 4478)
  AUTHORS   Kooistra,M.K., Leduc,R.Y., Dawe,C.E., Fairbridge,N.A.,
            Rasmussen,J., Man,J.H., Bujold,M., Juriloff,D., King-Jones,K. and
            McDermid,H.E.
  TITLE     Strain-specific modifier genes of Cecr2-associated exencephaly in
            mice: genetic analysis and identification of differentially
            expressed candidate genes
  JOURNAL   Physiol Genomics 44 (1), 35-46 (2012)
   PUBMED   22045912
REFERENCE   3  (bases 1 to 4478)
  AUTHORS   Dawe,C.E., Kooistra,M.K., Fairbridge,N.A., Pisio,A.C. and
            McDermid,H.E.
  TITLE     Role of chromatin remodeling gene Cecr2 in neurulation and inner
            ear development
  JOURNAL   Dev Dyn 240 (2), 372-383 (2011)
   PUBMED   21246654
REFERENCE   4  (bases 1 to 4478)
  AUTHORS   Fairbridge,N.A., Dawe,C.E., Niri,F.H., Kooistra,M.K., King-Jones,K.
            and McDermid,H.E.
  TITLE     Cecr2 mutations causing exencephaly trigger misregulation of
            mesenchymal/ectodermal transcription factors
  JOURNAL   Birth Defects Res A Clin Mol Teratol 88 (8), 619-625 (2010)
   PUBMED   20589882
REFERENCE   5  (bases 1 to 4478)
  AUTHORS   Banting,G.S., Barak,O., Ames,T.M., Burnham,A.C., Kardel,M.D.,
            Cooch,N.S., Davidson,C.E., Godbout,R., McDermid,H.E. and
            Shiekhattar,R.
  TITLE     CECR2, a protein involved in neurulation, forms a novel chromatin
            remodeling complex with SNF2L
  JOURNAL   Hum Mol Genet 14 (4), 513-524 (2005)
   PUBMED   15640247
REFERENCE   6  (bases 1 to 4478)
  AUTHORS   Liu,L., Amy,V., Liu,G. and McKeehan,W.L.
  TITLE     Novel complex integrating mitochondria and the microtubular
            cytoskeleton with chromosome remodeling and tumor suppressor RASSF1
            deduced by in silico homology analysis, interaction cloning in
            yeast, and colocalization in cultured cells
  JOURNAL   In Vitro Cell Dev Biol Anim 38 (10), 582-594 (2002)
   PUBMED   12762840
REFERENCE   7  (bases 1 to 4478)
  AUTHORS   Tate,P., Lee,M., Tweedie,S., Skarnes,W.C. and Bickmore,W.A.
  TITLE     Capturing novel mouse genes encoding chromosomal and other nuclear
            proteins
  JOURNAL   J Cell Sci 111 (Pt 17), 2575-2585 (1998)
   PUBMED   9701556
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000004.1.
            
            On Jul 17, 2010 this sequence version replaced XM_575657.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               JAXUCZ010000004.1  155562789-155562914
            127-221             JAXUCZ010000004.1  155618272-155618366
            222-405             JAXUCZ010000004.1  155628393-155628576
            406-545             JAXUCZ010000004.1  155629928-155630067
            546-650             JAXUCZ010000004.1  155630785-155630889
            651-700             JAXUCZ010000004.1  155632856-155632905
            701-870             JAXUCZ010000004.1  155633900-155634069
            871-954             JAXUCZ010000004.1  155641712-155641795
            955-1108            JAXUCZ010000004.1  155649846-155649999
            1109-1238           JAXUCZ010000004.1  155651853-155651982
            1239-1276           JAXUCZ010000004.1  155653674-155653711
            1277-1368           JAXUCZ010000004.1  155653797-155653888
            1369-1495           JAXUCZ010000004.1  155654675-155654801
            1496-1800           JAXUCZ010000004.1  155655852-155656156
            1801-1926           JAXUCZ010000004.1  155657619-155657744
            1927-2770           JAXUCZ010000004.1  155657856-155658699
            2771-4196           JAXUCZ010000004.1  155661056-155662481
            4197-4308           JAXUCZ010000004.1  155664288-155664399
            4309-4478           JAXUCZ010000004.1  155665461-155665630
FEATURES             Location/Qualifiers
     source          1..4478
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..4478
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /note="CECR2, histone acetyl-lysine reader"
                     /db_xref="GeneID:500308"
                     /db_xref="RGD:1564182"
     CDS             1..4314
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /note="cat eye syndrome chromosome region, candidate 2
                     homolog; cat eye syndrome chromosome region, candidate 2
                     homolog-like"
                     /codon_start=1
                     /product="cat eye syndrome critical region protein 2"
                     /protein_id="NP_001178906.1"
                     /db_xref="GeneID:500308"
                     /db_xref="RGD:1564182"
                     /translation="MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEEL
                     EAALHRDDVDFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLRE
                     ASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFY
                     GTRMYKEDPVQGRSNGELSLSRESERQKNVSNVPGKTGKRRGRPPKRKKLQEEIISSE
                     KQEENSLTSDLQTRNGSRGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLS
                     EDFLPEICNMIAQKGKRPQRTKPELQHRFMSDHLSIKSTKLEETPMLTKIEKQKRKEE
                     EEERQLLLAVQKKEQEQMLKEERKRELEEKVKAVEDRAKRRKLREERAWLLAQGKELP
                     PELSHLDLNSPMREGKKTKDIFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPN
                     YYQIIKIPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGDSSEYTKMSENLE
                     RCFHRAMTKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSSGSHVWTRSRDTEGSSRK
                     QPPMENGGKSLPPARRAASSGDDQSSSSIQLPPERPAASGTFGSLQGSDPTNLHGSSR
                     IPEVPPGEPLQHPPFAIQAPVGISNHRGSRLSAPEEKMCGGLTHLSNMGSHVPSLQLG
                     QMNCNSQDGNIYPPAPFQAGFIPSRHGGTPARPPDFPESSEIPPSHIYHSYKYLNRVH
                     PAVWNGNHGTTNPGRLGPDEKPLVGPGASHHPHALGHMMDGRVMRQPIPPNQWTKQSS
                     FLPPGVPSSGYMQPPCKSAGHRLQPPPTPAPSPRFRGPSQALRGAQGGESMMDSPEMI
                     AMQQLSSRVCPPGVPYHPRQPTPPQLPGPFPQVAHSASVCVSAPKPALDNPGSTQEIS
                     ETQEPEGDRAEPVPGLEEKAASICSSEGLYLKQLPHPAPPLSASCTRQSSPHERETED
                     SQLKSDASDSADTYKASKNKNPWPLDNSYNSAAVQGALHGGRDLAIVTERGNLPENGV
                     VGEASPCRSEGKGLGGSGSEKPLCPRGKTLQETVPCTGQNATTPPCTDPNLMAGTVNQ
                     FSPLYMPGIEYSNSATHYPMSPSLQGLGSMMGAKSPGSQPQSFSPRSFQANGPHPGLF
                     PRYRPQQGMRYSYQPSSQPSYHPYQRTPYYTCPQGFSDWQRSLPSQRSPSGPPGSHPP
                     RPLFSDKNALTSLQGCETLNAALTSPTQMDAVAAKVVPPDGHNSGPEEEKMDESMERP
                     ESPKEFLDLDNHNAATKRQSSLSTNDYLYGAPPPPLSSGMTFGSSAFPPHSVMLQTGS
                     PYTPQRSASHFQPRAYASPVPAHPPPHPVATQPNGLSPEGPLYCCQEEGLGHFQAAMM
                     EQTGTGSGIRGSFQDAHRPPGLQMHPIQSQSLFPKTPAPAASPEQLPPHKAPTLPLDQ
                     S"
     exon            1..126
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            127..221
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            222..405
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            406..545
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            546..650
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            651..700
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            701..870
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            871..954
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1108
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1238
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1276
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1368
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1495
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1800
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1926
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            1927..2770
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            2771..4196
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            4197..4308
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
     exon            4309..4478
                     /gene="Cecr2"
                     /gene_synonym="RGD1564182"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtgcccgg aggaaggcgg cgcggccggg ctgggcgagc tccgctcctg gtgggaagtc
       61 ccggccatcg cgcacttctg ctcgctcttt cgcacggcgt tccgcctgcc ggacttcgag
      121 atcgaggagt tagaggcagc tcttcacaga gatgacgtgg attttatcag tgatctgatt
      181 gcctgcctgc ttcaaggctg ttaccagcga agagacatca cgcctcagac attccacagc
      241 tacctggaag atatcatcaa ctaccgttgg gagcttgaag aaggaaagcc caatcctctg
      301 agagaagcca gtttccaaga ccttcctctg cgtactcgag tggagatcct gcatcgcctc
      361 tgtgattacc ggcttgatgc ggatgatgtc tttgatcttc tcaagggtct ggatgcagac
      421 agtctccgag ttgaacctct aggtgaagac aattcaggtg ccctctattg gtacttttat
      481 gggacacgaa tgtacaaaga agacccagta caaggaaggt ccaatggaga actctctttg
      541 agcagggaaa gtgaaaggca aaaaaatgtc tcaaatgttc ctggaaaaac aggcaaaaga
      601 agaggaaggc ctccaaaacg aaaaaaacta caggaggaga ttatatccag tgaaaagcag
      661 gaagaaaact ccttgacatc tgacctacag acaagaaatg gatccagagg gccaggccaa
      721 ggtacttggt ggctcctgtg tcaaacagaa gaagaatgga gacaggtcac tgagagcttc
      781 cgagagagga cctctctcag agagcggcaa ctctacaagc tcctcagcga ggacttcctg
      841 cctgaaatct gcaacatgat tgcccagaag ggaaaacgtc cacagcgcac aaagccagag
      901 ttgcaacata ggtttatgtc tgaccacctg tccatcaaat ccaccaagct agaggagaca
      961 cccatgctca ccaagataga aaaacagaag cgcaaggagg aggaggaaga acgacagctc
     1021 cttcttgcag tgcagaagaa ggagcaagag cagatgttaa aggaggagag aaagcgggaa
     1081 ttggaggaaa aggtcaaggc agtggaagat cgagctaaga ggagaaagct cagggaagaa
     1141 cgagcgtggc tattggctca aggcaaggag ctacccccag aactttccca tttggacctg
     1201 aattctccca tgagggaagg aaagaagacc aaggacatct ttgaactgga tgacgatttc
     1261 acagccatgt ataaagttct agatgtggtg aaggctcaca aggattcctg gcccttcttg
     1321 gaacctgtgg atgaatctta tgcccccaac tattaccaga ttattaagat ccccatggat
     1381 atttcaagca tggagaagaa attaaatgga ggtttatatt gtaccaagga ggaatttgta
     1441 aatgacatga agaccatgtt cagaaattgc cgaaagtaca atggggacag tagtgaatat
     1501 accaagatgt ctgaaaattt agagcgttgt ttccatcggg ccatgacaaa acattttcct
     1561 ggtgaagatg gagacacaga tgaagaattt tggatcagag aggatgaaaa acgggaaaaa
     1621 aggaggagtc gggctggtcg aagtagtgga agccacgttt ggacgcgctc cagagacaca
     1681 gaagggtcca gcaggaaaca gccaccaatg gaaaatggag gaaaatcatt gcctccggca
     1741 cgccgagctg cctcctcagg ggatgatcag agtagcagtt ctatacaact ccctccagag
     1801 aggccagcag catcaggaac atttggctct ctacaaggat cagatcccac caacttacat
     1861 ggctcctctc gaatcccaga ggtaccccca ggagagccct tgcagcaccc gccctttgct
     1921 atacaggctc cagttggaat tagtaaccac cgagggtccc ggctcagtgc tccagaagag
     1981 aagatgtgtg gggggctgac acacctttcc aatatgggat cacatgtccc atccttgcag
     2041 cttgggcaga tgaattgtaa cagtcaagat ggaaacatat atccaccagc tccattccag
     2101 gcaggattta ttccttctcg gcatggtggg actccagccc gaccaccaga ctttcctgaa
     2161 agctctgaaa ttcctcccag tcacatttat cactcataca agtatctgaa tcgagtacac
     2221 cctgctgttt ggaatgggaa ccatggtact acaaaccctg gacgattggg gccagatgag
     2281 aagcccctcg tggggccagg agcctctcac caccctcatg cccttggtca tatgatggat
     2341 ggccgagtga tgagacaacc tatcccacca aaccagtgga ctaaacaatc aagctttcta
     2401 cctcccggag ttccttcctc ggggtatatg cagccaccct gtaagtctgc tggacatcga
     2461 ttgcagccac ctccaactcc agcaccaagt cctcggttca gaggaccctc ccaggccctg
     2521 cggggggcac aaggagggga atccatgatg gacagccctg agatgattgc catgcagcag
     2581 ctctcctccc gagtctgtcc cccgggtgtg ccttaccacc cccgccagcc cactcctccc
     2641 cagttacctg gtccctttcc gcaggtagct cattctgcat cagtatgtgt gtcagcgccc
     2701 aagcctgcac tagacaaccc tgggagtaca caggagatca gcgagacaca agagcctgag
     2761 ggtgaccgag cagagcctgt gcctggactt gaggagaaag cagcaagcat ttgttcttca
     2821 gaagggctat acctcaaaca gctacctcac ccagcacctc ccttgtcagc cagctgtacc
     2881 aggcaaagtt caccacatga aagggaaaca gaggactccc aactcaaaag tgatgcttca
     2941 gactctgcag acacttacaa agcatcaaag aataaaaatc cttggccttt ggacaatagc
     3001 tacaacagcg cagctgtgca aggagcgctc catggtggca gagacctcgc catagtgaca
     3061 gaaagaggga atctacctga aaatggggtt gttggtgagg catctccctg tagatcagag
     3121 gggaagggcc ttggtggtag cggttcagaa aagccactct gccccagggg taaaacattg
     3181 caagaaaccg ttccatgtac aggacagaat gcaactacac ctccttgcac agatcccaat
     3241 ttgatggcag gcactgtgaa ccagttttct cccttataca tgcctggcat agaatactct
     3301 aactcagcta cacattaccc tatgagtcca agcttgcaag gcttgggctc tatgatggga
     3361 gcaaagtccc caggatcaca gcctcagtcc ttctctccca ggagtttcca ggctaacggt
     3421 ccccatcctg gactctttcc ccggtaccgc ccccaacagg gaatgagata ttcctaccag
     3481 ccttcttctc agccttccta ccacccctat cagcggactc cttattatac atgtccacag
     3541 ggcttttctg attggcagag atctctccct tcccagagaa gcccaagtgg acccccaggg
     3601 agtcaccctc cacgtcccct cttctcagat aagaatgcct tgactagtct gcaaggttgt
     3661 gagacactaa atgctgcctt aacttcacca actcaaatgg atgcagtggc tgctaaagtt
     3721 gttccacctg atggacacaa ttctggtcca gaagaagaaa agatggatga atctatggag
     3781 aggccagaga gtcccaaaga atttttagat ctggacaacc ataatgcagc taccaagcgt
     3841 cagagctcac tgtccaccaa tgactatctc tatggagccc caccaccacc tctgagttca
     3901 gggatgactt ttggttcatc cgctttccca ccccacagtg tgatgctgca gacagggtct
     3961 ccgtacactc ctcagcggtc agccagtcat tttcagccca gggcatatgc atcccctgtg
     4021 cctgcccatc cacctcccca tccagtggct acccagccca atggcctctc tccagagggt
     4081 cccctctact gctgtcagga agagggctta ggtcactttc aggctgcgat gatggagcag
     4141 acgggcactg gaagcggaat aagaggctca tttcaagatg cacacagacc gccaggattg
     4201 caaatgcatc caatccagtc acagtcctta ttcccaaaga ccccggcacc tgcagcatca
     4261 ccagaacagt tgccaccaca taaggcccca acacttcctc tggatcagag ctagtccagg
     4321 gaggagctaa gccccaagga aatggacggc tgcatgtgaa gacagaaggc cggccaggag
     4381 gattggagga ataatgactg ttgtacatct ctgttctgtc atcctgctcc acctctttgc
     4441 tttgagtcaa gccatcttca gagctgaact gcataggc
//
