LOCUS       NM_001108701            4004 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus CCAAT/enhancer binding protein zeta (Cebpz),
            mRNA.
ACCESSION   NM_001108701 XM_001059054 XM_343002
VERSION     NM_001108701.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4004)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4004)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 4004)
  AUTHORS   Shakib K, Norman JT, Fine LG, Brown LR and Godovac-Zimmermann J.
  TITLE     Proteomics profiling of nuclear proteins for kidney fibroblasts
            suggests hypoxia, meiosis, and cancer may meet in the nucleus
  JOURNAL   Proteomics 5 (11), 2819-2838 (2005)
   PUBMED   15942958
REFERENCE   4  (bases 1 to 4004)
  AUTHORS   Yamamoto CM, Banaiee N, Yount NY, Patel B and Selsted ME.
  TITLE     Alpha-defensin expression during myelopoiesis: identification of
            cis and trans elements that regulate expression of NP-3 in rat
            promyelocytes
  JOURNAL   J Leukoc Biol 75 (2), 332-341 (2004)
   PUBMED   14634060
  REMARK    GeneRIF: demonstrated that proximity of the CAAT box and a putative
            polyoma enhancer-binding protein 2/core-binding factor PEBP2/CBF
            site was important for defensin NP-3 promoter activity.
REFERENCE   5  (bases 1 to 4004)
  AUTHORS   Alonso CR, Pesce CG and Kornblihtt AR.
  TITLE     The CCAAT-binding proteins CP1 and NF-I cooperate with ATF-2 in the
            transcription of the fibronectin gene
  JOURNAL   J Biol Chem 271 (36), 22271-22279 (1996)
   PUBMED   8703044
REFERENCE   6  (bases 1 to 4004)
  AUTHORS   Lum LS, Sultzman LA, Kaufman RJ, Linzer DI and Wu BJ.
  TITLE     A cloned human CCAAT-box-binding factor stimulates transcription
            from the human hsp70 promoter
  JOURNAL   Mol Cell Biol 10 (12), 6709-6717 (1990)
   PUBMED   2247079
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_343002.3, XM_001059054.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4004
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..4004
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /note="CCAAT/enhancer binding protein zeta"
                     /db_xref="GeneID:362686"
                     /db_xref="RGD:1304994"
     exon            1..167
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..3149
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /note="core-binding factor"
                     /codon_start=1
                     /product="CCAAT/enhancer-binding protein zeta"
                     /protein_id="NP_001102171.1"
                     /db_xref="GeneID:362686"
                     /db_xref="RGD:1304994"
                     /translation="MSADQEPLEFLAKNPWRPKEVTEDPDEEDEEDSDEAKNGFSLEE
                     VLRLGGTKQDYLMLATLDENEEVVDGGKKGTIDDLQQGELEAFIQNLNLAKYSKSLIE
                     EDEPEKKENTSKKEAKLPKVENKKQKAAEGKKKNKSVPEQHPESSTVFKAKRDKQPDA
                     FEFLERQALLLKPGGKWYDMEYSGEFSLEPQPWDVVSKYKALAEKLYEQEVGLFKNKT
                     SNQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHTLQFVETLLSLVRKKGSKQQC
                     LMALDTFKELLITDLLPDSRKLRLFSQRPLHKLEELSSGNKDSRDRRLILWYYEHQLK
                     HLVAEFVQVLETLSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVINKLGDPQNRI
                     ATKASHLLEVLLRKHPNMKGVVCGELERLLFRSNISPKAQYYAICFLNQMVLSHEESE
                     LANKLITLYFCFFRTCIKKKDIESKMLSAILTGVNRAYPYSQIGDDRVREQVDTLFKV
                     LHVVNFNTSVQALMLLFQVMNSQQTISDRYYTALYKKMLDPGLTTCSKQAMFLNLIYK
                     SLKADIMLRRVKAFVKRLLQVTCTQMPPFICGALYLVSEILKAKPDLRSQLDDHPESD
                     EENFVDVGDDSDDEKFTDADRETATDAVEEVEAKEAEPESSTETEKPKAASWVHFDNL
                     KGGKQIKTYDPFSRNPLFCGAEHTNLWELRKLSEHFHPSVALFAKTILEGNHIQYSGD
                     PLQDFTLMRFLDRFVYRNPKLHKGKENTDSVVMQPKRKHFMKNVRDLAVNSKEFLAKE
                     ESQIPVDEVFFYRYYKKVAVTKDKQKRNADEDSIEDVDDEEFENMIDTFEDDNCFTPG
                     KDDMDFASNMKKIKGAKDDLEDSESSDDELGDLDDDEVSLGSMNDEDFEIDEDGGTFM
                     DVSDDESDHVPEFGEASPKASTKKSKRKSEDDFDFAGSFQGQKKKKKSFNDSSLFVSA
                     EEFGHLLDENMGSKFDTTGMNAMANKDNASFKQLKWEAERDDWLHNRDVKSIIKKKKN
                     FRKKKAPQKPKRQRK"
     exon            168..1642
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1874
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2061
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2062..2150
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2204
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2307
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2308..2376
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2443
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2544
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..2602
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2603..2787
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2788..2874
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2875..2933
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3015
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
     exon            3016..4004
                     /gene="Cebpz"
                     /gene_synonym="Cbf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccagcctac aatgtcggcg gaccaggaac ctttagagtt ccttgccaag aatccctggc
       61 gtcccaaaga ggtgacagaa gatccagacg aggaagacga ggaggatagc gatgaggcca
      121 agaatggctt ctctctggag gaggtgttac gcctcggagg cacgaagcaa gattacctta
      181 tgctggctac tttggatgaa aatgaagaag tagtagatgg aggcaaaaag ggaaccatcg
      241 acgacctcca acaaggtgaa ttggaggcat ttattcagaa tctgaatttg gccaaatact
      301 cgaagtctct gattgaagag gatgaaccag agaaaaaaga aaacaccagc aaaaaagaag
      361 caaaactacc gaaggtagag aataagaaac agaaagcagc agaaggaaaa aagaaaaata
      421 aaagcgtacc agagcagcat cccgagagca gtaccgtctt caaagcgaag agggataaac
      481 agcccgatgc attcgaattt ctagagagac aggcgctgtt actcaagcct gggggcaagt
      541 ggtacgacat ggaatacagc ggtgagtttt ccttggaacc acagccttgg gatgtagtgt
      601 ccaagtacaa agccctggcc gagaagctgt acgagcagga agtcggctta ttcaagaata
      661 agacaagcaa tcaaaaggga ggctcctcca cctggatgaa ggcaatcgtg tcatcgggga
      721 cgctagccga caggatggca gccatgatcc ttctgatcca ggatgacgct gttcacacac
      781 tccagtttgt agaaaccctc ttgagccttg ttagaaagaa gggcagcaag cagcagtgcc
      841 tcatggcttt ggatacgttc aaggagctgc tcatcaccga ccttcttccg gacagtcgga
      901 agctccggct cttcagccag cgcccccttc acaaactgga agagctgtcc agtggcaaca
      961 aggactcaag agatagaaga ctgatcctgt ggtattacga gcaccaactg aagcacttgg
     1021 tagcagaatt tgttcaggtc ctcgagactt taagtcacga ttccctggta accaccaaaa
     1081 cccgagccct ggtagcggcc catgagcttc tctgtgataa acccgaggag gaaaaggctc
     1141 ttcttgtgca ggtgataaat aagctgggag accctcagaa cagaatcgcc accaaagctt
     1201 cccatctgct agaagtgttg ctgcggaagc atcccaatat gaagggagtc gtgtgtggag
     1261 aactagaacg gctactcttt cgctcaaata tcagccccaa agctcagtat tatgcaattt
     1321 gctttttaaa ccaaatggtc ctctcccatg aagaaagtga gctggctaac aaattaataa
     1381 ctctttattt ttgtttcttt cggacttgta tcaagaaaaa agacattgaa tcaaaaatgc
     1441 tcagtgccat tttaacaggc gtgaacagag cgtaccctta ctcccagata ggtgacgaca
     1501 gagtgaggga gcaggtggac actttattca aagtgttgca tgttgtaaat tttaatacta
     1561 gtgtgcaggc tttaatgcta cttttccagg taatgaattc tcagcagaca atatctgacc
     1621 gatactacac agctttatac aaaaagatgt tagatccggg gttgacgaca tgttccaagc
     1681 aagcgatgtt tcttaacctg atctacaaat ctttgaaagc tgacatcatg ctacgccggg
     1741 tgaaggcttt tgtgaagagg ttacttcagg ttacctgcac acagatgcca ccattcattt
     1801 gtggagcctt atatcttgtg tctgagattc ttaaagcaaa accagattta agaagccagc
     1861 tagatgatca tccggaatct gatgaagaaa acttcgttga cgtgggagat gacagtgacg
     1921 atgaaaagtt taccgatgca gacagagaaa cagcaacaga tgcggtggag gaagtggagg
     1981 cgaaggaggc tgagcctgag agcagcacag aaaccgagaa gccgaaggct gcttcctggg
     2041 tgcactttga caatttgaaa ggtggcaagc agataaagac atatgatcca ttcagtagaa
     2101 atcctttatt ctgtggagct gaacatacaa atctttggga gctcagaaag ctatctgaac
     2161 atttccaccc ttctgtggcc ctctttgcaa agactatcct tgagggaaat cacattcagt
     2221 attcagggga cccactgcag gatttcacac tcatgagatt cctggaccga tttgtatacc
     2281 gaaatccaaa gctacataaa ggcaaagaaa ataccgacag cgtggtgatg caacccaaaa
     2341 ggaagcactt tatgaagaat gtgcgggatc ttgctgtgaa tagtaaagag ttccttgcaa
     2401 aagaagaaag ccagatccca gtggatgaag tgttcttcta caggtattac aaaaaagttg
     2461 ctgtcactaa agacaaacag aaacggaatg cagatgaaga cagtatagaa gatgttgatg
     2521 atgaagaatt tgaaaatatg attgacacat ttgaagatga caactgcttc acgcctggaa
     2581 aggatgatat ggattttgcc agtaatatga aaaaaataaa aggagctaaa gatgacttgg
     2641 aagactcgga gagcagtgac gatgagctcg gtgacctgga tgacgacgag gtctccctag
     2701 gaagtatgaa tgatgaagac tttgaaattg atgaagatgg aggaacattc atggatgtgt
     2761 cagatgacga aagtgaccat gttccagaat ttggtgaagc cagccccaaa gccagtacta
     2821 agaaaagcaa gaggaagagt gaagatgatt ttgactttgc tgggtcattt caaggacaaa
     2881 agaaaaagaa gaaaagtttc aatgactcca gcctgtttgt ctctgctgaa gagtttggtc
     2941 atctgttgga tgaaaatatg ggctccaagt ttgatacgac tggcatgaac gccatggcta
     3001 acaaagacaa tgcaagtttc aaacagctca agtgggaagc tgagcgtgat gattggctcc
     3061 acaacagaga tgtgaaaagt atcatcaaga aaaagaagaa tttcaggaaa aagaaagccc
     3121 ctcagaaacc caaaagacaa aggaagtgac agcgtcagag tgaataataa gttaagatca
     3181 tacttaccct taatttttgc tatccaacca tttttgctga tctttttctc taaccccata
     3241 cattccagac tgttcaatgg atttgtaata aactgtggaa acaaggtgct gtcatttata
     3301 caattatgat aaagttaaac ttatattgaa aaaattcttc catattactt cataacaatg
     3361 aaagggacag cagggctcct tccctgctcg agctgtaacc actctcctga ccactgggag
     3421 ctgcttgttg aggcaccggg tgccatgctt aagttaggta catgacgtca ttgtggtcaa
     3481 ctcttaactg tccaggtagg cactggctct tccccagaga aagcagcatc tctgagaaca
     3541 cagcctttta cagcagtaac tggtttgtgc ccatccccat cttaggtctc actctggaat
     3601 ctgttcttaa ccactgagag aattaaaact ccagtttgca gggtggggta aataataact
     3661 tttgtggggt atttgtaaag tctgaaagtt aattaataaa aaaggtaatg aggattaaaa
     3721 caagagctaa ctgttctcat ctaagtaatt aggtgtgagt ccctactatg tggtcccagg
     3781 aggcaactag tgtcagaaaa taataacaaa ataatgtcac ttgctctaaa gttgtaaagt
     3841 accacagagt ttataggtta ttttacactt gaatttttac ttgagaaaaa acataccttc
     3901 caaaatgaag ggaaatgtct tgctcattgt ttgcctgaaa tctgatattt aaaaaaaaaa
     3961 aaaaaaaaac actgtattaa catattaaac cacaatttaa taat
//
