LOCUS       NM_013154               1139 bp    mRNA    linear   ROD 23-JUL-2024
DEFINITION  Rattus norvegicus CCAAT/enhancer binding protein delta (Cebpd),
            mRNA.
ACCESSION   NM_013154
VERSION     NM_013154.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Chen,N., Xu,Y., Liu,Y., Zhao,H., Liu,R. and Zhang,Z.
  TITLE     CEBPD aggravates apoptosis and oxidative stress of neuron after
            ischemic stroke by Nrf2/HO-1 pathway
  JOURNAL   Exp Cell Res 440 (1), 114127 (2024)
   PUBMED   38857839
  REMARK    GeneRIF: CEBPD aggravates apoptosis and oxidative stress of neuron
            after ischemic stroke by Nrf2/HO-1 pathway.
REFERENCE   2  (bases 1 to 1139)
  AUTHORS   Lipponen,A., El-Osta,A., Kaspi,A., Ziemann,M., Khurana,I., Kn,H.,
            Navarro-Ferrandis,V., Puhakka,N., Paananen,J. and Pitkanen,A.
  TITLE     Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA
            methylation regulate chronic transcriptomics changes after
            experimental traumatic brain injury
  JOURNAL   Acta Neuropathol Commun 6 (1), 17 (2018)
   PUBMED   29482641
  REMARK    GeneRIF: Four upregulated transcription factors Pax6, Tp73, Cebpd,
            and Spi1, appeared as potent regulators of chronic post-traumatic
            brain injury (TBI) gene expression. They regulate molecular
            networks contributing to post-injury secondary damage, including
            apoptosis and inflammation, strengthening the feasibility of
            therapeutically targeting these molecular networks even after the
            acute post-TBI period.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1139)
  AUTHORS   McCarthy,T.L. and Centrella,M.
  TITLE     Androgen receptor activation integrates complex transcriptional
            effects in osteoblasts, involving the growth factors TGF-beta and
            IGF-I, and transcription factor C/EBPdelta
  JOURNAL   Gene 573 (1), 129-140 (2015)
   PUBMED   26187065
  REMARK    GeneRIF: DHT activated AR inhibits gene transactivation by
            C/EBPdelta, and transgenic C/EBPdelta expression inhibits AR
            activity
REFERENCE   4  (bases 1 to 1139)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   5  (bases 1 to 1139)
  AUTHORS   Arguello,A.A., Ye,X., Bozdagi,O., Pollonini,G., Tronel,S.,
            Bambah-Mukku,D., Huntley,G.W., Platano,D. and Alberini,C.M.
  TITLE     CCAAT enhancer binding protein delta plays an essential role in
            memory consolidation and reconsolidation
  JOURNAL   J Neurosci 33 (8), 3646-3658 (2013)
   PUBMED   23426691
  REMARK    GeneRIF: C/EBPdelta plays a critical role in both memory
            consolidation and reconsolidation.
REFERENCE   6  (bases 1 to 1139)
  AUTHORS   Sekine,O., Nishio,Y., Egawa,K., Nakamura,T., Maegawa,H. and
            Kashiwagi,A.
  TITLE     Insulin activates CCAAT/enhancer binding proteins and
            proinflammatory gene expression through the phosphatidylinositol
            3-kinase pathway in vascular smooth muscle cells
  JOURNAL   J Biol Chem 277 (39), 36631-36639 (2002)
   PUBMED   12145301
  REMARK    GeneRIF: CEBPB and CEBPD regulate PI3K inflammatory gene expression
REFERENCE   7  (bases 1 to 1139)
  AUTHORS   Carmona,M.C., Iglesias,R., Obregon,M.J., Darlington,G.J.,
            Villarroya,F. and Giralt,M.
  TITLE     Mitochondrial biogenesis and thyroid status maturation in brown fat
            require CCAAT/enhancer-binding protein alpha
  JOURNAL   J Biol Chem 277 (24), 21489-21498 (2002)
   PUBMED   11940593
REFERENCE   8  (bases 1 to 1139)
  AUTHORS   Penner,G., Gang,G., Sun,X., Wray,C. and Hasselgren,P.O.
  TITLE     C/EBP DNA-binding activity is upregulated by a
            glucocorticoid-dependent mechanism in septic muscle
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 282 (2), R439-R444 (2002)
   PUBMED   11792653
REFERENCE   9  (bases 1 to 1139)
  AUTHORS   Kolyada,A.Y., Johns,C.A. and Madias,N.E.
  TITLE     Role of C/EBP proteins in hepatic and vascular smooth muscle
            transcription of human NHE1 gene
  JOURNAL   Am J Physiol 269 (6 Pt 1), C1408-C1416 (1995)
   PUBMED   8572170
REFERENCE   10 (bases 1 to 1139)
  AUTHORS   Kageyama,R., Sasai,Y. and Nakanishi,S.
  TITLE     Molecular characterization of transcription factors that bind to
            the cAMP responsive region of the substance P precursor gene. cDNA
            cloning of a novel C/EBP-related factor
  JOURNAL   J Biol Chem 266 (23), 15525-15531 (1991)
   PUBMED   1714459
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAHX01070471.1
            and M65149.1.
            
            On Feb 13, 2007 this sequence version replaced NM_013154.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                AAHX01070471.1     5667-5697
            32-1139             M65149.1           1-1108
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1139
                     /gene="Cebpd"
                     /gene_synonym="C/EBPd; CELF"
                     /note="CCAAT/enhancer binding protein delta"
                     /db_xref="GeneID:25695"
                     /db_xref="RGD:2328"
     exon            1..1139
                     /gene="Cebpd"
                     /gene_synonym="C/EBPd; CELF"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..839
                     /gene="Cebpd"
                     /gene_synonym="C/EBPd; CELF"
                     /note="c/EBP delta; transcription factor CELF; C/EBPdelta;
                     CCAAT/enhancer binding protein (C/EBP), delta;
                     C/EBP-delta"
                     /codon_start=1
                     /product="CCAAT/enhancer-binding protein delta"
                     /protein_id="NP_037286.1"
                     /db_xref="GeneID:25695"
                     /db_xref="RGD:2328"
                     /translation="MSAALFSLDSPARGAPWPTEPAAFYEPGRVGKPGRGPEPGDLGE
                     PGSTTPAMYDDESAIDFSAYIDSMAAVPTLELCHDEIFADLFNSNHKAAGAGSLELLQ
                     GGPTRPPGVGSIARGPLKREPDWGDGDAPGSLLPAQVAVCAQTVVSLAAAAQPTPPTS
                     PEPPRGSPGPSLAPGPVREKGAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQE
                     MQQKLVELSAENEKLHQRVEQLTRDLASLRQFFKELPSPPFLPPTGTDCR"
ORIGIN      
        1 caacttggac gccaggccca gccgacgccg ccatgagcgc cgctcttttc agcctagaca
       61 gcccagcacg cggcgcaccc tggcccacag agcccgcggc cttctacgag ccaggcaggg
      121 tgggcaagcc aggacgaggg ccggagcctg gggatctggg ggagccgggc tccacgaccc
      181 ctgccatgta tgacgacgag agcgccatcg acttcagcgc ctacattgat tccatggctg
      241 ccgtgcccac cctagagttg tgccacgacg agatcttcgc cgacctcttc aacagcaatc
      301 acaaagcggc cggcgcgggc agcctggagc tgctgcaggg cggccctacg cgacccccgg
      361 gtgtggggtc aatcgccagg ggcccgctga agcgcgaacc cgactggggc gacggcgacg
      421 cgccgggctc cctgctgccg gcgcaagtgg cagtgtgcgc gcagacagtg gtgagcttgg
      481 cggccgcggc acagcccaca ccacccactt cgcccgagcc tcctcgaggc agccctggac
      541 cgagccttgc gcctggcccc gtccgagaga agggcgccgg caagaggggt ccggaccggg
      601 gcagccctga gtaccggcag cgacgcgagc gcaacaacat cgctgtgcgc aagagccggg
      661 acaaggccaa gcgccgcaac caggagatgc agcagaagct ggtggagctg tcggccgaga
      721 acgagaagct gcatcagcgt gtggagcagc tcacccggga cctggccagc ctccggcagt
      781 tcttcaaaga gctgcccagc ccgcctttcc tgccgcccac cggcaccgac tgccggtaac
      841 gcgcggtgtg ggccttagag actccgaacg accgatacct cagaccccga cggcggggag
      901 cagacgccgc ccgaattgct acagtttctt gggcactgga ctgcgagaga agctatatga
      961 atccccctta aattattttt ttataatggt agcgttttct acgtcttatt accattgcag
     1021 ctaaggtaca ttgtagaaaa gacttttccg acagactttt gtagataaga ggaagagact
     1081 gcgcatgctt tttatattca tttttacagt atttgtaaga ataaagaagc atttaaatt
//
