LOCUS       NM_001106942            1615 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus caudal type homeo box 4 (Cdx4), mRNA.
ACCESSION   NM_001106942 XM_001055316 XM_228569
VERSION     NM_001106942.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Bei L, Huang W, Wang H, Shah C, Horvath E and Eklund E.
  TITLE     HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10
            transcription in myeloid cells
  JOURNAL   J Biol Chem 286 (21), 19047-19064 (2011)
   PUBMED   21471217
REFERENCE   2  (bases 1 to 1615)
  AUTHORS   Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M,
            van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M and
            Deschamps J.
  TITLE     Cdx and Hox genes differentially regulate posterior axial growth in
            mammalian embryos
  JOURNAL   Dev Cell 17 (4), 516-526 (2009)
   PUBMED   19853565
REFERENCE   3  (bases 1 to 1615)
  AUTHORS   van Nes J, de Graaff W, Lebrin F, Gerhard M, Beck F and Deschamps
            J.
  TITLE     The Cdx4 mutation affects axial development and reveals an
            essential role of Cdx genes in the ontogenesis of the placental
            labyrinth in mice
  JOURNAL   Development 133 (3), 419-428 (2006)
   PUBMED   16396910
REFERENCE   4  (bases 1 to 1615)
  AUTHORS   Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R and
            Rossant J.
  TITLE     Interaction between Oct3/4 and Cdx2 determines trophectoderm
            differentiation
  JOURNAL   Cell 123 (5), 917-929 (2005)
   PUBMED   16325584
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473969.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_228569.2, XM_001055316.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN13663604,
                              SAMN13663613 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..1615
                     /gene="Cdx4"
                     /gene_synonym="RGD1561529"
                     /note="caudal type homeo box 4"
                     /db_xref="GeneID:302400"
                     /db_xref="RGD:1561529"
     exon            1..684
                     /gene="Cdx4"
                     /gene_synonym="RGD1561529"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1037
                     /gene="Cdx4"
                     /gene_synonym="RGD1561529"
                     /codon_start=1
                     /product="homeobox protein CDX-4"
                     /protein_id="NP_001100412.1"
                     /db_xref="GeneID:302400"
                     /db_xref="RGD:1561529"
                     /translation="MYGSCLLEKEAGMYPGTLRNPGGGSTAGVGTSGGSGSPLPASNF
                     TAAPVYPHYMGYPHMSNMDPHGPSLGAWSSPYSPPREDWSTYPGPSSTMGTVPMNDMT
                     SSSPAFGSPDYSTLGPTGGAGGASNGGSLPDAASESLVSIDSGTSGGATSPSRSRHSP
                     YAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSELAVNLGLSE
                     RQVKIWFQNRRAKERKMIKKKISQFENSGGSVQSDSGSISPGELPNAFFTTPSAVRGF
                     QPIEIQQVIISE"
     exon            685..830
                     /gene="Cdx4"
                     /gene_synonym="RGD1561529"
                     /inference="alignment:Splign:2.1.0"
     exon            831..1615
                     /gene="Cdx4"
                     /gene_synonym="RGD1561529"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttagggtagg ataggaaggt tggagtagtc cgagccgccc agaggagctg gcagcacagc
       61 gagtgctgac ccattcattg atagcctctt gcatctcaaa ctcgggttgg cgctaagttt
      121 acagggtcct caggatggct tagggggcaa cttcttctat ccaagccacc atgtatggaa
      181 gctgcctttt agaaaaagaa gcgggaatgt acccaggcac tctcaggaac cctggaggag
      241 gcagcacagc cggagtgggc acctctgggg gcagtggtag tcctctgcct gcctccaact
      301 ttactgcagc cccagtttac ccacactaca tggggtatcc acatatgtcc aacatggatc
      361 ctcacgggcc ttcgctggga gcctggagct caccctacag tccgccccgg gaagactgga
      421 gtacataccc tgggccgtcc agcacaatgg gcacagtgcc catgaacgac atgacctcga
      481 gctccccagc tttcggctcc ccagactaca gcactctggg ccccactggc ggtgcaggcg
      541 gtgcaagcaa cggcggtagc ctgccagacg cggccagcga gtcactggtt tccatcgact
      601 caggcacctc tggcggcgcc acttctccca gcaggagccg ccacagcccc tacgcgtgga
      661 tgcgcaagac tgtgcaggtg accgggaaaa ccaggacaaa agaaaagtat cgtgtggtct
      721 acacggatca tcaaaggctg gagctggaaa aggaatttca ctgcaataga tacattacca
      781 tccggaggaa gtcagagctg gcagttaacc tgggcctttc tgagagacag gtgaaaatct
      841 ggtttcagaa tcgcagagcc aaggagagga agatgatcaa aaagaaaatc tcccagtttg
      901 agaacagtgg aggttccgtg caaagtgact ctggctccat cagccccgga gaactgccta
      961 atgctttctt caccactcca tctgctgtcc gtgggtttca gccaattgag atacagcagg
     1021 tcataatttc tgaatgaaac gggagcagag aaaccaacgc atccttcctg ttacagtgtc
     1081 tctttggcct ctaagataac agcagggcag ttgagatcgg atatacttcc ttataaggca
     1141 caattccaaa caagtagaca caccatgagt tggagatatt tcagaagact ctaatattaa
     1201 gaaaaatctt atttcatgct gtcaaatggg cactgggcag aaagctgtgc gatacgtttt
     1261 tctacttaaa gtctagattc aagagccctt gaaactttgt ttacaatttc agaaactcat
     1321 ttgttcctat gctcttgtgt ttgttatttg attctgagta tcttcctggt ctttttaggg
     1381 gataggagta aggtaagcat acatttctct atctggagac attgtttgga gggagtaatt
     1441 aaaaaaccac cagtcttttt aacaagctaa ctgtgtaaaa cagcatcaag aagtgattac
     1501 gaatctattg gttaattaca tgaagatcac ttttcccttt gaataatact cacttaccat
     1561 caattacctg gtcatagaat ttagaagatt tatttcaaat cgtgtcaaaa caatg
//
