LOCUS       NM_001014000            2280 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus CDKN2A interacting protein (Cdkn2aip), mRNA.
ACCESSION   NM_001014000 XM_224846
VERSION     NM_001014000.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Cheung,C.T., Singh,R., Kalra,R.S., Kaul,S.C. and Wadhwa,R.
  TITLE     Collaborator of ARF (CARF) regulates proliferative fate of human
            cells by dose-dependent regulation of DNA damage signaling
  JOURNAL   J Biol Chem 289 (26), 18258-18269 (2014)
   PUBMED   24825908
REFERENCE   2  (bases 1 to 2280)
  AUTHORS   Hasan,M.K., Yaguchi,T., Minoda,Y., Hirano,T., Taira,K., Wadhwa,R.
            and Kaul,S.C.
  TITLE     Alternative reading frame protein (ARF)-independent function of
            CARF (collaborator of ARF) involves its interactions with p53:
            evidence for a novel p53-activation pathway and its negative
            feedback control
  JOURNAL   Biochem J 380 (Pt 3), 605-610 (2004)
   PUBMED   15109303
REFERENCE   3  (bases 1 to 2280)
  AUTHORS   Wadhwa,R., Sugihara,T., Hasan,M.K., Duncan,E.L., Taira,K. and
            Kaul,S.C.
  TITLE     A novel putative collaborator of p19ARF
  JOURNAL   Exp Gerontol 38 (3), 245-252 (2003)
   PUBMED   12581788
REFERENCE   4  (bases 1 to 2280)
  AUTHORS   Hasan,M.K., Yaguchi,T., Sugihara,T., Kumar,P.K., Taira,K.,
            Reddel,R.R., Kaul,S.C. and Wadhwa,R.
  TITLE     CARF is a novel protein that cooperates with mouse p19ARF (human
            p14ARF) in activating p53
  JOURNAL   J Biol Chem 277 (40), 37765-37770 (2002)
   PUBMED   12154087
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085832.1.
            
            On Apr 20, 2005 this sequence version replaced XM_224846.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085832.1, CK603813.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q11"
     gene            1..2280
                     /gene="Cdkn2aip"
                     /gene_synonym="RGD1305302"
                     /note="CDKN2A interacting protein"
                     /db_xref="GeneID:306455"
                     /db_xref="RGD:1305302"
     exon            1..594
                     /gene="Cdkn2aip"
                     /gene_synonym="RGD1305302"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..2056
                     /gene="Cdkn2aip"
                     /gene_synonym="RGD1305302"
                     /note="collaborator of ARF"
                     /codon_start=1
                     /product="CDKN2A-interacting protein"
                     /protein_id="NP_001014022.1"
                     /db_xref="GeneID:306455"
                     /db_xref="RGD:1305302"
                     /translation="MAQEVSEYLSQNPRVAAWVETLRCEGETDKHWRHRREFLLRNAG
                     DLVPATEETADAESGARSRQLQQLVSFSMAWANHVFLGCRYPQKVMDKILSMAEGIKV
                     TDAPIHTTRDELVAKVKKRGISSSNEGVEEPSKKRSIEGKNNSSVERDHGKKSAKTDR
                     SAQQENSSGSKGSSTKSESSGTSARSNSGVSHQNSSTSEGDRSVCSQSSSNSSQVTSA
                     GSGKASEPEAPDKHGSASFVSSLLKSSLNSHVTKSTDSRQHSGSPRKNALEGSSVSVS
                     QSSSEIEVPLLGSSGSSEVELPLLSCKSSSETASSGLTTKASSEANISSSVSKNSSSS
                     GTSLLMPKSSSTNTSLLTSQVAASLLASKSSSQSSGSVASKSTSLGSMSQLASKSSSQ
                     SSTSQLPSKSTSQSSESSVKFTCRKLTNEDIKQKQPFFNRLYKTVAWKLVAVGGFSPN
                     VNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGK
                     SKENAKAVASREALKLFLKKKVVVKICKRKYRGNEIEDLVLLDEESRPVNLPPALKHP
                     QELL"
     exon            595..725
                     /gene="Cdkn2aip"
                     /gene_synonym="RGD1305302"
                     /inference="alignment:Splign:2.1.0"
     exon            726..2255
                     /gene="Cdkn2aip"
                     /gene_synonym="RGD1305302"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcctgcccc tcagtcgcct cggctccgcc tcagccgggc gcgccctccg accgaggtgg
       61 gcgcaaccgc tgagtcgccg gcggctgggc gctgcaaagc atcctgggag aacgcgctcg
      121 cgccggaagg gcgcgcgagt gcgcggcggc agcgaggtta taaaagggag cgagccagcg
      181 gcaggcggaa gtgggcggtt cgtcggcgcc ttgttctgtt gtttggtgtt tgggcttctg
      241 gaggggcgtt ctcgggaggg ccgccggtgc aggccgcgct gacagggccg ctcgccgctc
      301 cgccctgtgc gctcgcgctc tcctcgtctc gcagggtccc aacatggcgc aggaggtatc
      361 cgagtacctg agccagaacc cgcgagtagc cgcctgggtg gagacccttc gctgcgaggg
      421 cgagacggac aaacactggc gccaccgccg ggagtttctg cttcgcaatg ccggggacct
      481 ggtccccgcg accgaggaga ctgcggacgc ggaaagcgga gcccgcagtc ggcagctaca
      541 gcagctcgtc tccttctcca tggcctgggc aaaccatgtc ttcctagggt gccggtaccc
      601 tcaaaaagtt atggataaaa ttcttagtat ggctgaaggc atcaaagtga cagatgctcc
      661 aatccatacc acacgagacg aactggttgc caaggtgaag aaaagaggga tatcgagtag
      721 caatgaaggg gtagaagagc catccaaaaa acgatccata gaaggaaaaa acaattcttc
      781 agttgagcga gatcatggga aaaaatctgc caaaacagat cgttcagctc agcaagaaaa
      841 cagttcagga tccaaggggt cgtccaccaa atcagagagt agtgggacct cagctcggag
      901 caactctggt gtctcccatc agaatagttc cacaagtgaa ggcgatagat ctgtttgcag
      961 ccaaagcagc agcaattcct ctcaggtaac atcagcaggg tctggaaaag cttctgagcc
     1021 agaagctcca gataaacatg gttcagcatc ctttgtttct tcactgttaa aatccagtct
     1081 gaatagtcat gtgacgaaat ccactgattc cagacagcat agtggatcac ctagaaagaa
     1141 tgctttggaa ggttcttcag tttcagtttc tcagagcagc tcagagattg aggtgccctt
     1201 gttgggttcc tccggaagct cagaagtaga gttgccatta ctgtcttgta agtctagttc
     1261 agagacagct tcgagtgggt taacaaccaa agctagttca gaggcaaaca tttcatcatc
     1321 agtttctaaa aacagttcct catcaggcac ctctttacta atgcccaaga gcagttcaac
     1381 aaatacatca ctactgactt ctcaggtagc tgcatcactg ttagcttcca aaagcagctc
     1441 ccagagcagt ggatctgtgg cttccaaaag cacttcctta ggaagcatgt ctcagctagc
     1501 ttctaagagt agttctcaga gtagcacttc acagttgcct tctaaaagta cctcacagtc
     1561 cagtgagagt tctgtcaaat tcacttgtcg gaagttaacc aatgaagaca taaagcagaa
     1621 gcagcctttc ttcaatagac tgtataagac agtggcgtgg aagttggtag cagttggtgg
     1681 ctttagcccc aatgtgaatc atggcgagct gctaaatgca gctattgagg ctctgaaagc
     1741 aacactagat gtgttttttg tcccactgaa agaactggca gatctgcctc aaaataagag
     1801 ctctcaagaa agtattgtat gtgaattgag gtgtaaatcg gtgtatttgg gcactggctg
     1861 tgggaaaagc aaagaaaatg caaaagcagt cgcatcaaga gaggcactta agttatttct
     1921 caagaagaag gtggtggtaa agatctgtaa aaggaagtac agaggcaatg agatagaaga
     1981 tctagtactc ctcgatgaag aatcaagacc tgtaaactta cctccagcac tgaaacatcc
     2041 tcaagaatta ctgtgattcc ccaaggtatc actgcatcca gtacctgggg tttgaagaga
     2101 aaaactggct tttatatgaa acactggctt tcacagattt tatattgctt ttttccagtt
     2161 ttgcagaaaa tttaaattct agttctcttc attaaagtag agctgtaaat aatttatgaa
     2221 tgacagtgca tattaaaggg tatacactga cagcaaaaaa aaaaaaaaaa aaaaaaaaaa
//
