LOCUS       NM_001100506            1522 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus cyclin-dependent kinase 18 (Cdk18), mRNA.
ACCESSION   NM_001100506 XM_001059896 XM_213886
VERSION     NM_001100506.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1522)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1522)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
REFERENCE   3  (bases 1 to 1522)
  AUTHORS   Hirose,T., Tamaru,T., Okumura,N., Nagai,K. and Okada,M.
  TITLE     PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly
            expressed in terminally differentiated neurons
  JOURNAL   Eur J Biochem 249 (2), 481-488 (1997)
   PUBMED   9370357
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC082045.1.
            
            On or before Aug 4, 2007 this sequence version replaced
            XM_213886.4, XM_001059896.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082045.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1522
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..1522
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /note="cyclin-dependent kinase 18"
                     /db_xref="GeneID:289019"
                     /db_xref="RGD:1309523"
     exon            1..133
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..1365
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /EC_number="2.7.11.22"
                     /note="serine/threonine-protein kinase PCTAIRE-3; PCTAIRE
                     protein kinase 3; cell division protein kinase 18;
                     PCTAIRE-motif protein kinase 3"
                     /codon_start=1
                     /product="cyclin-dependent kinase 18"
                     /protein_id="NP_001093976.1"
                     /db_xref="GeneID:289019"
                     /db_xref="RGD:1309523"
                     /translation="MNKMKNFKRRLSLSVPRPETIEESLTEFTEQFNQLHTQRNEDGR
                     DEPGQLSPGVQYQQRQNQRRFSMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLT
                     RMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGA
                     PCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHN
                     VKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSN
                     EVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLL
                     GTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGINLLTSLLLYESKSRMS
                     AEAALSHPYFQSLGERVHQLDDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSI
                     F"
     exon            134..213
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            214..339
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            340..396
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            397..511
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            512..606
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            607..669
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            670..793
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            794..914
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1012
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1118
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1161
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1252
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1330
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1486
                     /gene="Cdk18"
                     /gene_synonym="PCTAIRE3; Pctk3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgctgatca tgaacaagat gaagaacttc aaacgaaggc tttccctgtc agtgccccgc
       61 ccagagacca ttgaggagtc attgaccgag ttcaccgagc agttcaacca gctccacact
      121 cagaggaatg aggacggcag ggacgaacct gggcagctgt ctccgggcgt gcagtatcag
      181 caacggcaga accagcgccg attctccatg gaggacctca acaagaggct ctctctgccc
      241 atggatatcc gcctgcccca ggaattcctg cagaagctac agctggagaa cccagggctg
      301 cccaaaccac tcacccgaat gtcccgccgt gcctccctgt cagatatcgg cttcgggaaa
      361 ctggaaacat acgtgaaact ggacaaactg ggggagggca cctatgccac cgtcttcaag
      421 ggacgcagca agttgacaga gaacctcgtg gccctgaagg agatccggtt ggaacatgag
      481 gaaggggcac cctgcactgc tattcgagag gtgtctctgc tgaaggacct gaaacatgcc
      541 aatattgtga ccctgcatga cctcattcac acagatcggt ccctcaccct ggtgtttgag
      601 tacctggaca gtgacctgaa acagtaccta gaccactgcg ggaacctcat gaacatgcac
      661 aacgtcaaga tttttatgtt ccagctgctc cggggtctgg cctattgcca ccgccgcaag
      721 atcctacacc gggacctgaa gccccagaac ctgctcatca atgagagggg ggaactgaaa
      781 ctggctgact ttggcctggc ccgggccaaa tcagtgccta caaagaccta ctccaatgag
      841 gtggtgaccc tctggtacag gcccccagac gtgctgctgg gatccacgga gtactccacc
      901 cccatcgaca tgtggggcgt gggctgcatc ctctatgaga tggccaccgg caagcccctc
      961 ttcccaggct ccactgtcaa ggaggagttg cacctcatct tccgtctcct ggggacacct
     1021 acagaagagt cgtggccagg tgtgacatcc atctccgagt ttcgagccta caacttcccc
     1081 cggtacctac cgcaaccgct gctcagccac gctcccaggt tggatactga aggcatcaac
     1141 ctcctgacca gcctcctcct gtatgaatcc aagagtcgca tgtcagcaga ggcggcccta
     1201 agtcacccct acttccagtc tctcggggaa cgagtacacc agctcgatga cactgcctcc
     1261 atcttctccc tgaaggagat ccagctccaa aaggacccag gctatcgtgg ccttgccttc
     1321 cagcacccag ggcgagggaa gagccggcga cagagcatct tctgagctac ccacccggct
     1381 gcacgttgag ggacgagagg ccactcggaa catgaattca ggaagtgtgg ggcctgtgtg
     1441 gccatcagag ggctgaacaa tgaatgcctg tggccagtct ggaggaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaaaaaaaa aa
//
