LOCUS       NM_138525               2696 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus cadherin-related family member 5 (Cdhr5), mRNA.
ACCESSION   NM_138525
VERSION     NM_138525.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2696)
  AUTHORS   Crawley,S.W., Shifrin,D.A. Jr., Grega-Larson,N.E., McConnell,R.E.,
            Benesh,A.E., Mao,S., Zheng,Y., Zheng,Q.Y., Nam,K.T., Millis,B.A.,
            Kachar,B. and Tyska,M.J.
  TITLE     Intestinal brush border assembly driven by protocadherin-based
            intermicrovillar adhesion
  JOURNAL   Cell 157 (2), 433-446 (2014)
   PUBMED   24725409
REFERENCE   2  (bases 1 to 2696)
  AUTHORS   Hinkel,I., Duluc,I., Martin,E., Guenot,D., Freund,J.N. and Gross,I.
  TITLE     Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor
            of growth and beta-catenin activity in colon cancer cells
  JOURNAL   Gastroenterology 142 (4), 875-885 (2012)
   PUBMED   22202456
REFERENCE   3  (bases 1 to 2696)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2696)
  AUTHORS   Goldberg,M., Peshkovsky,C., Shifteh,A. and Al-Awqati,Q.
  TITLE     mu-Protocadherin, a novel developmentally regulated protocadherin
            with mucin-like domains
  JOURNAL   J Biol Chem 275 (32), 24622-24629 (2000)
   PUBMED   10801787
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_138525.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF221952.1, BC098904.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-133               JAXUCZ010000001.1  205810960-205811092 c
            134-309             JAXUCZ010000001.1  205810704-205810879 c
            310-360             JAXUCZ010000001.1  205810298-205810348 c
            361-453             JAXUCZ010000001.1  205808082-205808174 c
            454-555             JAXUCZ010000001.1  205807842-205807943 c
            556-666             JAXUCZ010000001.1  205807622-205807732 c
            667-837             JAXUCZ010000001.1  205807363-205807533 c
            838-928             JAXUCZ010000001.1  205806737-205806827 c
            929-1026            JAXUCZ010000001.1  205806558-205806655 c
            1027-1227           JAXUCZ010000001.1  205806254-205806454 c
            1228-1341           JAXUCZ010000001.1  205806008-205806121 c
            1342-1426           JAXUCZ010000001.1  205805848-205805932 c
            1427-2002           JAXUCZ010000001.1  205805174-205805749 c
            2003-2163           JAXUCZ010000001.1  205803505-205803665 c
            2164-2696           JAXUCZ010000001.1  205802686-205803218 c
FEATURES             Location/Qualifiers
     source          1..2696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..2696
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /note="cadherin-related family member 5"
                     /db_xref="GeneID:171554"
                     /db_xref="RGD:620504"
     exon            1..133
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..2628
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /note="mucin and cadherin-like protein; GP100;
                     mu-protocadherin; mucin and cadherin like"
                     /codon_start=1
                     /product="cadherin-related family member 5 precursor"
                     /protein_id="NP_612534.1"
                     /db_xref="GeneID:171554"
                     /db_xref="RGD:620504"
                     /translation="MGAPALLWPPLLLPLLTVLFGHLPGTLAQAQVCSANQTVFTMNE
                     NTTVSGPLADIFVPEDQYVTLGQLSTPNAFKVEGNKLFLIVTPDYEENSLLEAVLECK
                     RGDTLVTQFRVFVAVLDINDNAPEFPFTIKEYNVSEDTRVNTIVIPETELKATDADKD
                     DILVYTLQEVTPNASKFFSLVGINSPALKLDQTLDYYKSPNMTFRLLARDTREENVIP
                     SHTATATVVLNVLPADLRTPWFLPCSFTDDYFCIQAQYHTVIPTGHKLPSPLILSPGP
                     IYAVDGDQAINQPIVYSIMMGNTDDTFIINKDDGNLTMAKSIPSPMTFTLVVRAEQAD
                     MARYSVTQAVVEARDVTGNPLQFSQSLYFGTVVLGSEAGTAVKDKTFPSEILRIQAQY
                     LGFPDLNSAVTYQVTNSSEFIMNKDILLTTVPMETERTIRIEVEANNTVTKDIATTIV
                     EIQVSEREPPSTESPTPPEAGGTTGPSSNTTLETPSTSGTSQGPATTSSGGSAGPFPP
                     AGTTLSPLTSAPTVPGGSPTLGISTSPQTATPGGDATQTPKPGTSQPMVPTPGASTSS
                     QPATPSGSSTQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPRPGTSQPMVPTPGA
                     STSSQPATPSGSTQTPKPGTSQPTTTGPISGVGELGDGQRFSTVDMAVLGGVLGALLL
                     LALIFLIILIHKHYRHRFTCCSGKAKEPQPSGYDNLTFLPDNKAKWSPTSNRKPEPGP
                     EPVQPPLRPPSPMSSSPTPPSSMPPSPQPKASGSPKTVQAGDSPSAVRSILTKERRPE
                     GEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDDDPDQKKSLRLGAV
                     ADNTYV"
     exon            134..309
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            310..360
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            361..453
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            454..555
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            556..666
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            667..837
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            838..928
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1026
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1227
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1341
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1426
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..2002
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2163
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2696
                     /gene="Cdhr5"
                     /gene_synonym="Mucdhl; Mupcdh"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagccggccg gacccttctt ccaggtgaca gctgccacca tgggggctcc ggccctcctg
       61 tggcctcccc tgctgttgcc attgctcacg gtgctgtttg gccaccttcc agggaccttg
      121 gcccaggctc aggtctgctc tgcgaaccag accgtgttta caatgaacga gaacaccact
      181 gtttctgggc cactggcgga catttttgtc ccagaagacc agtatgtgac cttgggacag
      241 ttgtccaccc ctaatgcctt taaggttgag ggcaataagc tgtttctcat cgtgactcca
      301 gattatgagg aaaactcttt gctggaggca gtcctggagt gtaagagagg agatactttg
      361 gtgacacagt tcagggtgtt tgtggctgtc ctggacatca atgacaatgc accagaattc
      421 ccctttacaa tcaaggaata taatgtatcg gaggacacca gagtgaatac gatcgtcatc
      481 cctgagacag agctgaaggc tacagatgct gacaaagatg acatcctagt ctacactctg
      541 caggaagtga cccccaatgc cagcaagttc ttctccctgg tgggcataaa ctcccctgct
      601 ctgaagttgg accagactct ggattactac aagagtccga acatgacctt caggctgctg
      661 gcacgggata ctagggaaga gaatgtaatt cccagccata cggccactgc caccgtggtc
      721 ttgaacgtgc tgccagctga cctacggacc ccctggttcc tgccgtgctc ctttacggat
      781 gactacttct gcattcaggc ccagtaccac acagttatcc ccacaggaca caaactgcca
      841 tcccctctca tcttgagtcc tggtcccatc tatgctgtgg acggagatca ggccattaac
      901 cagcctatcg tctacagcat tatgatggga aacacggatg acacatttat catcaacaaa
      961 gacgatggca acctcacgat ggccaaaagt atccccagcc ccatgacctt caccctggtg
     1021 gtcagggctg agcaggctga catggctcga tactcagtga ctcaggccgt tgtggaggct
     1081 cgagatgtca ctgggaaccc actccagttc tctcagagcc tgtactttgg cacggtggta
     1141 ctgggttctg aggctggcac agcagtgaag gacaagacct tcccttcaga gatcctgagg
     1201 atccaggctc agtacctagg cttcccggac ctcaactcgg ctgtcacata tcaagtcacc
     1261 aactcctcag aattcatcat gaataaggat atcttgctga ccactgtgcc tatggagaca
     1321 gaaagaacaa tccgcataga ggtagaagct aacaatactg tgactaaaga catagccacc
     1381 actattgtgg agatccaggt gtcagagcga gagccgccct ccacagagtc ccccacaccc
     1441 ccagaagctg gaggaacaac tgggccttca agtaacacca ctttggaaac cccctcgacc
     1501 tctgggacct ctcaaggacc tgccacaacc agctctgggg gaagtgctgg cccattccca
     1561 cctgcaggca caactctaag cccactcacc tctgccccaa ctgtacctgg ggggtcccct
     1621 actcttggaa tcagcacctc tccccagaca gctactcctg gtggggatgc aacacagacc
     1681 cccaaaccag gtacctctca gccaatggtc cccactccag gggctagcac ctcttctcag
     1741 ccagccacac ctagtggcag ctcaacccag acccccaaac caggaacctc tcagccaatg
     1801 gtccccactc caggggctag cacctcttct cagccagcca cacctagtgg cagctcaacc
     1861 cagaccccca ggccaggaac ctctcagcca atggtcccca ctccaggggc cagcacctct
     1921 tctcagccag ccacacctag tggctcaaca cagaccccca agccaggaac ctctcagccg
     1981 acaaccactg ggcccatatc aggagtaggc gagctgggtg atggccagag attttccacg
     2041 gtggacatgg cagtgttggg cggggtgcta ggggcactgc tgttgctggc cctcatcttc
     2101 ttgatcatcc tcatccataa gcactaccga catcggttca cttgctgctc tggcaaggca
     2161 aaggagccac agccaagtgg ctatgacaac ctgaccttcc tcccagacaa caaggccaag
     2221 tggtcaccca cctccaaccg gaagccagag ccgggccctg agcctgtcca gccgcccctc
     2281 cggcctccta gtcccatgtc ttccagtccc acgcccccca gctccatgcc tcctagccct
     2341 cagcccaaag cttccgggtc tcccaagaca gtccaggcag gggacagtcc ttcagccgtg
     2401 aggtctatcc tgactaagga gcggcggccg gagggggagg gcggctacaa ggctgtgtgg
     2461 ttcggcaagg acatcggggc agaggctgat gtggtggttc tcaacgaacc caccgccgac
     2521 gtggacagcg ccagtgcctc gggaagtgag gggagcgatg atgatgatga ccctgaccag
     2581 aagaagagtc tccgccttgg cgcagtcgca gacaacactt acgtctagct cagcgcccgg
     2641 actctccgcc ccaagccact cccctttcct cctctaatta aagtagcact ttcgaa
//
