LOCUS       NM_053572               4275 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cadherin-related family member 1 (Cdhr1), mRNA.
ACCESSION   NM_053572 XM_346480
VERSION     NM_053572.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4275)
  AUTHORS   Duncan,J.L., Roorda,A., Navani,M., Vishweswaraiah,S., Syed,R.,
            Soudry,S., Ratnam,K., Gudiseva,H.V., Lee,P., Gaasterland,T. and
            Ayyagari,R.
  TITLE     Identification of a novel mutation in the CDHR1 gene in a family
            with recessive retinal degeneration
  JOURNAL   Arch Ophthalmol 130 (10), 1301-1308 (2012)
   PUBMED   23044944
REFERENCE   2  (bases 1 to 4275)
  AUTHORS   Ostergaard,E., Batbayli,M., Duno,M., Vilhelmsen,K. and Rosenberg,T.
  TITLE     Mutations in PCDH21 cause autosomal recessive cone-rod dystrophy
  JOURNAL   J Med Genet 47 (10), 665-669 (2010)
   PUBMED   20805371
REFERENCE   3  (bases 1 to 4275)
  AUTHORS   Yang,Z., Chen,Y., Lillo,C., Chien,J., Yu,Z., Michaelides,M.,
            Klein,M., Howes,K.A., Li,Y., Kaminoh,Y., Chen,H., Zhao,C., Chen,Y.,
            Al-Sheikh,Y.T., Karan,G., Corbeil,D., Escher,P., Kamaya,S., Li,C.,
            Johnson,S., Frederick,J.M., Zhao,Y., Wang,C., Cameron,D.J.,
            Huttner,W.B., Schorderet,D.F., Munier,F.L., Moore,A.T., Birch,D.G.,
            Baehr,W., Hunt,D.M., Williams,D.S. and Zhang,K.
  TITLE     Mutant prominin 1 found in patients with macular degeneration
            disrupts photoreceptor disk morphogenesis in mice
  JOURNAL   J Clin Invest 118 (8), 2908-2916 (2008)
   PUBMED   18654668
REFERENCE   4  (bases 1 to 4275)
  AUTHORS   Rattner,A., Smallwood,P.M., Williams,J., Cooke,C., Savchenko,A.,
            Lyubarsky,A., Pugh,E.N. and Nathans,J.
  TITLE     A photoreceptor-specific cadherin is essential for the structural
            integrity of the outer segment and for photoreceptor survival
  JOURNAL   Neuron 32 (5), 775-786 (2001)
   PUBMED   11738025
REFERENCE   5  (bases 1 to 4275)
  AUTHORS   Nakajima,D., Nakayama,M., Kikuno,R., Hirosawa,M., Nagase,T. and
            Ohara,O.
  TITLE     Identification of three novel non-classical cadherin genes through
            comprehensive analysis of large cDNAs
  JOURNAL   Brain Res Mol Brain Res 94 (1-2), 85-95 (2001)
   PUBMED   11597768
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053572.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB053449.1, SRR26360190.298072.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               JAXUCZ010000016.1  12883325-12883579   c
            256-351             JAXUCZ010000016.1  12882674-12882769   c
            352-497             JAXUCZ010000016.1  12881658-12881803   c
            498-548             JAXUCZ010000016.1  12880585-12880635   c
            549-638             JAXUCZ010000016.1  12879325-12879414   c
            639-725             JAXUCZ010000016.1  12877257-12877343   c
            726-842             JAXUCZ010000016.1  12875938-12876054   c
            843-986             JAXUCZ010000016.1  12874732-12874875   c
            987-1065            JAXUCZ010000016.1  12874305-12874383   c
            1066-1166           JAXUCZ010000016.1  12872949-12873049   c
            1167-1370           JAXUCZ010000016.1  12871040-12871243   c
            1371-1523           JAXUCZ010000016.1  12870436-12870588   c
            1524-1688           JAXUCZ010000016.1  12868538-12868702   c
            1689-1756           JAXUCZ010000016.1  12867934-12868001   c
            1757-1985           JAXUCZ010000016.1  12867115-12867343   c
            1986-2243           JAXUCZ010000016.1  12866252-12866509   c
            2244-4275           JAXUCZ010000016.1  12863696-12865727   c
FEATURES             Location/Qualifiers
     source          1..4275
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..4275
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /note="cadherin-related family member 1"
                     /db_xref="GeneID:93662"
                     /db_xref="RGD:620420"
     exon            1..255
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     CDS             201..2780
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /note="protocadherin-21; prCAD; photoreceptor cadherin;
                     MT-protocadherin"
                     /codon_start=1
                     /product="cadherin-related family member 1 precursor"
                     /protein_id="NP_446024.1"
                     /db_xref="GeneID:93662"
                     /db_xref="RGD:620420"
                     /translation="MRRGPQVALVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSL
                     PEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDRERED
                     EIEAIISISDGLNLVAEKVVIVVTDANDEAPRFLQEPYNILVPENTPAGSSIFKVQAE
                     DKDTGSGGSVTYFLQSLHSSKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGG
                     RLRGADVVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDR
                     GKPNHILYRLLNESDGLFEINETSGAISVLQSPAQLRREVYELHVQVTEVNSSGSPAA
                     QSTVPVIIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGA
                     NAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKSLTFKLLAIEVNTP
                     EKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVPGGSNVVAVTAVDPDTGPWGKV
                     QYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVT
                     LLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDID
                     AHTGEIRLKNSIRSLEALHNITPSGEYSWSLQVQAKDRGSPSFSTTALLKIDITDTER
                     LSRSSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRV
                     LRRRPSPAPHTVRIEWLKFRRAKAASKFILKEDPPNENCNNSRVGVTVPPRAPALPPP
                     PKMASSTVAQQTVPTVSGSLTPQPSQQLPTPKPLGGPAQSSLVSELKQKFEKKSLGNK
                     AYV"
     exon            256..351
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            352..497
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            498..548
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            549..638
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            639..725
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            726..842
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            843..986
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1065
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1166
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1370
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1523
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1688
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1756
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1985
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2243
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
     exon            2244..4275
                     /gene="Cdhr1"
                     /gene_synonym="Pcdh21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagccatcca gctgtgcgga ttcgagagca ctgtcatccg cttagcgcct tcgcaccacc
       61 cgcgctccct ccctccctcc actgccaccg ccaccgtcac ccacaacgtc gcctctgctc
      121 tcctaccgag ctcagggcat gctccgaggt ccagctcccg gcctcggcag tggccaggct
      181 ttcgaccctt ccgcggagac atgaggcgtg gcccacaggt tgccctggtc ctggggctgc
      241 tgtgcattta cctagcccag gccaactttg cccctcactt ctttgacaat ggagtgggca
      301 gcaccaacgg aaacatggcc ctgttcagcc tcccagaaga cactcctgta ggttctcatg
      361 tgtacacgct aaatgggact gaccctgagg gagaccctat ctcctaccat atcagctttg
      421 accccagcac tagaagtgtc ttttctgttg accccaattt tggaaacatc accctggtgg
      481 aagagctgga cagagagaga gaggatgaga tagaagccat catcagcatc tccgacggcc
      541 tgaacctggt ggcagagaaa gttgtgatag tggtgacaga tgccaatgat gaagcaccca
      601 ggttcctcca ggagccttac aacatcctgg ttccagagaa cacacctgct gggagcagca
      661 tctttaaggt acaggcagag gacaaggaca caggctctgg aggcagtgtc acctacttcc
      721 ttcagagcct acactcctcc aagttcaccg tagaccgtca cagcggggtg ctgcgactcc
      781 aggctggggc cacactggac tatgagaagt cgagggctca tttcatcact gtggttgcca
      841 aggatggtgg gggcaggctt cgaggagctg atgtggtgtt ctcagccacc acgactgtca
      901 ccatcaatgt ggaagatgtt caggacacag cccctatatt cgtgggtaca ccctactatg
      961 gttatgtgta cgaagacacc cttccgggct cagaggtgct gacggtggtt gccatagatg
     1021 gagaccgagg caaacccaac cacatcctct ataggctctt gaatgagagt gatggactct
     1081 ttgaaattaa tgagacatct ggagccatct ccgtccttca gagccctgcc cagctccgaa
     1141 gagaggtgta tgagcttcat gtacaggtga cagaggtcaa ctcttcagga agcccagctg
     1201 ctcagtccac agtcccagtg atcatcagga tcgtggacct caacaaccac cctccaacct
     1261 tctatggaga gagcgggccc cagaacaagt ttgaactatc tatgtttgag cacccgcccc
     1321 agggggaaat cctccgtgga ctcaagatca ctgtcaatga ctctgaccag ggagccaatg
     1381 ccaaattcaa cttacggctg gtgggacctg gaggcatctt tcgagtggtg ccacagacag
     1441 tcctgaatga agcccaagtg accatcatag tggaaaactc agctgccatt gactttgaaa
     1501 agtctaagtc gttaaccttc aagctcctgg ccattgaagt gaacaccccg gagaagttca
     1561 gctccacagc agacattgtg atccagcttc tggacaccaa tgataatgtt cccaagttca
     1621 cctctcacta ctacatcgcc aggatcccag agaatgttcc agggggctcc aatgtggtgg
     1681 ctgtcacagc tgtggatcca gatacaggac catggggcaa agtccagtat tccatttatg
     1741 ggaccggatc agacctcttc ttgattcacc catccactgg gcttatctac actcagccct
     1801 gggccagcct ggatgctgag ggcacttcga ggtacaactt ttatgtgaag gcagaagaca
     1861 tggatgggag gtacagcctg gctgaggtgt ttgtcactct gttggatgtc aatgaccact
     1921 acccccagtt tgtacagagt gtccaggaga agacgatggt gctggggacc ccactgaaaa
     1981 ttgaggccac agaccaggat gcagaggaac caaacaactt ggtcgactac tccattaccc
     2041 gtgcagagcc agtcaacgtg tttgacatag atgcacacac aggggagatc aggctcaaga
     2101 attccatccg ctccttggag gccctacaca acattacacc cagcggggaa tactcatggt
     2161 ccctacaggt gcaggccaag gaccgaggat ctccatcttt cagcacaaca gccttactca
     2221 agatcgacat cacagacaca gagaggctgt ccagaagctc catggctgcc ttcctgattc
     2281 agaccaagga caatcccatg aaggccgtgg gtgtactggc tggtgtcatg gccattgttg
     2341 tggccataac cgtcctcatc tccacagcca ccttctggcg taacaagaag tctaacaagg
     2401 tcctgcctgt gcggcgtgtg ctccgtagaa ggcccagccc tgcaccccac acagtacgaa
     2461 tagaatggct caaattccgg agggccaagg ctgcttccaa gtttatactc aaagaggatc
     2521 ctcccaatga gaactgcaat aacagcagag tgggagtcac ggtgccccca agagctccag
     2581 ctctcccacc gccccccaaa atggcatcca gtacagtggc ccaacagaca gtgcctactg
     2641 tctctggatc ccttacccca cagccatccc aacagttacc cacacccaaa cccctgggag
     2701 gccctgctca gtcttctttg gtgtcagagc tcaagcaaaa gtttgagaag aagagtttag
     2761 gtaacaaggc ttatgtctag agtgtgcccc ataatttttc tcttccttcc cccaatactg
     2821 accctgaagg tcacccctat tttgtataac gttgtaacac tgtatacagg gctctgcaaa
     2881 gggctttggg tgagggatgc ctcagactga tttggcaaat acatacccac tgttcaattc
     2941 cttggcatag ctataatgct ctctattcgt cagagaatag aagcgcataa ggagtcaagt
     3001 ctgtgcattt ctacccacca accctacatc ccacaatcac tggagtcctt ctggggcctt
     3061 gtcatcctta gttgagaaga agggcccctg agcatgaata acaagactgg caagagtcta
     3121 gatctccaag cttcagccaa caagcaggtc gaaggaggct ggttctcaac taaagttgaa
     3181 agtcagtgag ctttgtggga tgcagagaca caaatacagg caaagaaaag gactgaaacg
     3241 ctctgaaagc tggtgctgac tgtgtccgaa gccagtgaac aatagaatta gcatccagat
     3301 aagaggtgta aagtgagctc ttcctagact gagagcagaa atctccagcc tcccctgaag
     3361 agaccaggca aggtggtagg tgtacatcag atttgagctc agagaatgca tccattttga
     3421 tccagccctt ctcgtatcac gtgaccttgc ggataaagtt taaactccta ttgtcttctt
     3481 ccttgtccgt gagatgaaga aagcaaaccc taagaaagca gctttaagca agtgcgaagc
     3541 agcaggatta caaagtattt gttggaagcc agttctctgg ctacatctca tgaagaaagt
     3601 attaacaccc aggagggact atgttgagtc acagcctgat aatggctttc ccctaactca
     3661 cacagcttcc cttccgtccc cactttcctc cacgtcactg tcacaaagaa ccagaatcag
     3721 gcagtaagct ccagtccaag ttattttgac tcagacaggg aaatgaatct cctagggtta
     3781 ttggctccgt gcacacagta aatcggtggc agggattggt ctgagagctt ctattccaca
     3841 ctctttctct cattggaata tatcttattt atatgcgata ctcccgaaga gggaaatcct
     3901 gcaaactgga agattctggt gttcttttga gaaaacatta aggaaatata tatatactca
     3961 ctctatgaag ctctctagaa ttccacagtt atggatgtgg tcagagtgta tgaacatgtg
     4021 tttttcttga tctcccccac cccctatccc cagtctgtgt ttggaggtgt tacacagacg
     4081 tgtggatgtt cagagtcctg atctgtaggt ctgtagtcac tggcccgcac agtattgagg
     4141 gacaggcact aacctgctaa agaccagcct ggaaattgct gcgctggatc gtttgctacc
     4201 acagggagtt cagcatctga taatatgttg ctaacctctt ctgtaaatgg taaataaaat
     4261 ctattattca aagga
//
