LOCUS       NM_001012055            2894 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cadherin 16 (Cdh16), mRNA.
ACCESSION   NM_001012055 XM_226203
VERSION     NM_001012055.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Koumarianou,P., Gomez-Lopez,G. and Santisteban,P.
  TITLE     Pax8 controls thyroid follicular polarity through cadherin-16
  JOURNAL   J Cell Sci 130 (1), 219-231 (2017)
   PUBMED   27780871
  REMARK    GeneRIF: Pax8 controls apical-basal follicular polarization and
            follicle formation through Cdh16.
REFERENCE   2  (bases 1 to 2894)
  AUTHORS   Cali,G., Gentile,F., Mogavero,S., Pallante,P., Nitsch,R.,
            Ciancia,G., Ferraro,A., Fusco,A. and Nitsch,L.
  TITLE     CDH16/Ksp-cadherin is expressed in the developing thyroid gland and
            is strongly down-regulated in thyroid carcinomas
  JOURNAL   Endocrinology 153 (1), 522-534 (2012)
   PUBMED   22028439
REFERENCE   3  (bases 1 to 2894)
  AUTHORS   Wendeler,M.W., Praus,M., Jung,R., Hecking,M., Metzig,C. and
            Gessner,R.
  TITLE     Ksp-cadherin is a functional cell-cell adhesion molecule related to
            LI-cadherin
  JOURNAL   Exp Cell Res 294 (2), 345-355 (2004)
   PUBMED   15023525
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081996.1.
            
            On Feb 11, 2005 this sequence version replaced XM_226203.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081996.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p14"
     gene            1..2894
                     /gene="Cdh16"
                     /note="cadherin 16"
                     /db_xref="GeneID:307614"
                     /db_xref="RGD:1311638"
     exon            1..105
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            106..186
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2634
                     /gene="Cdh16"
                     /codon_start=1
                     /product="cadherin-16 precursor"
                     /protein_id="NP_001012055.1"
                     /db_xref="GeneID:307614"
                     /db_xref="RGD:1311638"
                     /translation="MISAWLWLLCFSVIQTFTAEAQPTESLHTEVPENYGGNFPFYIL
                     KLPLPLGKDEGQIVLSGDSGTAAENTFAVDPDSGFLVATRALDREEKAEYQLQVTLES
                     EDGQVLWGPQLVTVHVKDENDQVPQFSQAIYRAQLSQGTRPGVPFLFLEVSDGDAPGT
                     TNSDLRFHILSQFPVQPLPDMFQLDPQLGALALSPDGSTTLDHALEEHYQLLVQVKDM
                     GDQPSGHQAMATLEISIVENSWTPLEPVHLAENLRVAYPHSIAQVHWGGGDVHYQLES
                     QPPGPFEVDAEGRIHVTMELDREAQAEYQLQVRAQNSRGEDYAEPLELQVVVMDENDN
                     APVCSPHDPTISIPELSPPGTEVARLSAEDLDAPGSPNSHIVYQLLSPEPEQGAENKA
                     FEIDSTSGSVTLGTAPLHAGQNILLQVLAVDLAGSEGGLSSTCEVAVMITDINNHAPE
                     FINSQIGPISLPEDVKPGSLVATLMATDADLEPAFRLMDFAIEEGDPTGIFDLSRESD
                     SNHVQLRLRKNLSYEEAPDHKVVVVVRNVEELVGPGPGPAATATVTILVERVIPPLKL
                     DQESYETSIPVSTPAGSLLLTIQPSDPMNRTLRFSLVNDSEGWLCIKEVSGEVYTAQS
                     LQGAQPGDTYTVLVEAQDTDEPEMSTSTTIVVHFLKASPVPALILASGPSRHLCTPRQ
                     DYGVVVNGVSEDPGLANRNGPYSFALGPNPTVQRDWRLQPLNDSHAYLTLALHWVEPG
                     EYTVPVVVHHDAQMWQLQVQVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGVLLGTLAA
                     IGFILILVFTHLALARKDLDQPADSVPLKTAV"
     exon            187..276
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            277..432
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            433..571
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            572..730
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            731..927
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1050
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1201
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1429
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1506
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1695
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1937
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2071
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2314
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            2315..2422
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2539
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
     exon            2540..2868
                     /gene="Cdh16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccaccttg ccttgcccca ccttgcccga tttgccagag cttcctgaag aaggatctgt
       61 ctctcctgga aactgaacca aggaagaggc tttgggcatc agtagagtct catttctgtg
      121 tcccttgggc ctgccttgac catgatctct gcctggctgt ggctactttg cttctctgtt
      181 attcagactt tcaccgctga agcccagcct acagaaagcc tgcatacaga agtccctgaa
      241 aactatggtg gaaatttccc tttttacata ctcaagctac cactaccctt agggaaggat
      301 gaaggtcaga ttgtcctatc aggagactcg ggcacagcag ctgaaaacac ctttgctgtg
      361 gatccagatt ctggctttct ggtggcaacg agggccctgg accgggagga aaaggcagag
      421 taccaactcc aggtcacctt ggagtctgag gatggacaag tcttgtgggg tccacagctt
      481 gtgactgtgc atgtgaaaga tgagaatgac caggtacccc aattctccca ggccatctac
      541 agagctcagc tgagccaagg caccaggcct ggggtcccct tcctcttcct ggaggtttct
      601 gatggggatg caccaggcac aactaactca gaccttcgat tccacattct gagccagttc
      661 ccagttcagc ctttaccaga catgttccag ctggaccctc aactaggggc tctggccctt
      721 agtcccgatg gaagcaccac cctagatcat gcccttgaag agcattacca gctattggta
      781 caggtcaaag acatgggcga ccagccttca ggccaccagg ctatggcgac cttggagatc
      841 tccatagtag agaacagctg gacacccctc gagcctgttc acttggcaga gaatctcaga
      901 gtggcatacc cgcacagcat tgcccaggtg cactggggtg gaggggatgt gcattatcag
      961 ctggagagcc agcctccagg accctttgaa gtggatgcag aggggaggat ccatgttacc
     1021 atggaactgg acagagaggc tcaggctgag taccagctcc aagtccgagc tcagaattcc
     1081 cgtggtgagg actatgcaga acccctggag ttgcaggtgg tggtgatgga tgaaaatgac
     1141 aatgcacctg tctgctcccc acatgaccca acaatcagca tccctgagct cagtccccca
     1201 ggaactgaag tggccaggct ctcagcagag gatttggatg cccccggatc acccaattcc
     1261 cacattgtgt atcagttgtt gagccctgag cctgagcagg gagctgaaaa caaagccttc
     1321 gagatagatt caacctcagg cagtgtaaca ctgggaactg ccccactcca tgctggccag
     1381 aatatcctgc ttcaggtgct ggctgttgac ttagcaggat cagagggagg cctcagtagc
     1441 acatgtgagg tggcagtcat gatcacagac atcaacaacc atgcccctga gttcatcaat
     1501 tcccagattg ggcctataag tcttcctgag gatgtaaagc ctgggtctct ggtggccaca
     1561 ctcatggcca ctgatgctga ccttgagcct gctttccgcc ttatggactt cgccattgaa
     1621 gaaggagacc caacagggat ctttgacctg tccagggagt cagactctaa ccatgtccag
     1681 ctcagactcc ggaagaacct cagctatgag gaagctcctg atcacaaggt ggtggtggta
     1741 gtgcggaatg tagaggaact ggtaggccca ggtccaggcc ctgcagccac agccacagtc
     1801 actatactgg tggaaagggt gataccaccc ctcaagttgg accaggagag ctatgagacc
     1861 agcatcccag tcagcacccc agctggctcc ctcctgctga ccatccagcc ctcggacccc
     1921 atgaacagaa ccctcaggtt ctccctggtc aatgattcag agggctggct ctgcatcaag
     1981 gaggtgtctg gggaagtata cacagcccag tccctgcagg gtgcccagcc tggagacaca
     2041 tacacagtgc ttgtggaggc ccaagacaca gatgagccag aaatgagcac ttccaccacc
     2101 attgtggtcc acttcctgaa ggcttctcct gtcccagcat tgattctggc ctccgggccc
     2161 agccgacacc tctgtacacc ccgccaagac tacggtgtgg ttgtgaatgg ggtcagtgag
     2221 gaccctggcc tggccaacag gaatggtccc tacagctttg ctcttggtcc caatcccact
     2281 gtgcagcggg attggcgcct ccagcctctc aatgattccc acgcctacct caccttggca
     2341 ttgcactggg tagagcctgg tgaatacacg gtacctgtgg ttgtccacca tgatgcccaa
     2401 atgtggcaac tccaagtcca agtgatcgtg tgtcgctgca atgtggaggg tcaatgcatg
     2461 cgcaaggtgg gtcgcatgaa gggaatgccc acgaagctgt cagcggtggg tgtcctcttg
     2521 ggcaccctgg cagcgatagg tttcatcctc attcttgtct tcacacacct ggccctggcg
     2581 aggaaggacc tggatcagcc ggcagacagt gtgcccctga agacagccgt gtgagtgatc
     2641 taagcagccc cagctgggag gtctacccca gctccatctg atctcacgga gaaaggaccc
     2701 agaacccaag atgcactggg gaccaagagt ccttcacctt gttggagtgg agacactgtc
     2761 accaggcatg tccccaaagc ctgagcactt actttacagg acgaccatgg taatactcca
     2821 aatggcagct ctttgtccag taataaaggc tcagagagct agactggaaa aaaaaaaaaa
     2881 aaaaaaaaaa aaaa
//
