LOCUS       NM_001025050            1547 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cell division cycle associated 8 (Cdca8), mRNA.
ACCESSION   NM_001025050 XM_575906
VERSION     NM_001025050.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1547)
  AUTHORS   Wang,T., Dai,L., Shen,S., Yang,Y., Yang,M., Yang,X., Qiu,Y. and
            Wang,W.
  TITLE     Comprehensive Molecular Analyses of a Macrophage-Related Gene
            Signature With Regard to Prognosis, Immune Features, and Biomarkers
            for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and
            the LASSO Algorithm
  JOURNAL   Front Immunol 13, 843408 (2022)
   PUBMED   35693827
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1547)
  AUTHORS   Capalbo,L., Montembault,E., Takeda,T., Bassi,Z.I., Glover,D.M. and
            D'Avino,P.P.
  TITLE     The chromosomal passenger complex controls the function of
            endosomal sorting complex required for transport-III Snf7 proteins
            during cytokinesis
  JOURNAL   Open Biol 2 (5), 120070 (2012)
   PUBMED   22724069
REFERENCE   3  (bases 1 to 1547)
  AUTHORS   Parra,M.T., Gomez,R., Viera,A., Llano,E., Pendas,A.M., Rufas,J.S.
            and Suja,J.A.
  TITLE     Sequential assembly of centromeric proteins in male mouse meiosis
  JOURNAL   PLoS Genet 5 (3), e1000417 (2009)
   PUBMED   19283064
REFERENCE   4  (bases 1 to 1547)
  AUTHORS   Xia,F., Canovas,P.M., Guadagno,T.M. and Altieri,D.C.
  TITLE     A survivin-ran complex regulates spindle formation in tumor cells
  JOURNAL   Mol Cell Biol 28 (17), 5299-5311 (2008)
   PUBMED   18591255
REFERENCE   5  (bases 1 to 1547)
  AUTHORS   Vader,G., Kauw,J.J., Medema,R.H. and Lens,S.M.
  TITLE     Survivin mediates targeting of the chromosomal passenger complex to
            the centromere and midbody
  JOURNAL   EMBO Rep 7 (1), 85-92 (2006)
   PUBMED   16239925
REFERENCE   6  (bases 1 to 1547)
  AUTHORS   Sampath,S.C., Ohi,R., Leismann,O., Salic,A., Pozniakovski,A. and
            Funabiki,H.
  TITLE     The chromosomal passenger complex is required for chromatin-induced
            microtubule stabilization and spindle assembly
  JOURNAL   Cell 118 (2), 187-202 (2004)
   PUBMED   15260989
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079274.1.
            
            On Jun 25, 2005 this sequence version replaced XM_575906.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079274.1, SRR8487231.17980.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1547
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1547
                     /gene="Cdca8"
                     /note="cell division cycle associated 8"
                     /db_xref="GeneID:500545"
                     /db_xref="RGD:1566306"
     exon            1..222
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..995
                     /gene="Cdca8"
                     /note="cell division cycle-associated protein 8"
                     /codon_start=1
                     /product="borealin"
                     /protein_id="NP_001020221.1"
                     /db_xref="GeneID:500545"
                     /db_xref="RGD:1566306"
                     /translation="MAPKKRSSRGTRTNTLRSRKLASFLKDFDREVQVRTKQIESDRQ
                     TLLKEVENLYNIEVLRLPKALQVMKWLDYFALGGNRQALEEAATADRDITEINNLTAE
                     AIQTPLKSVKKRKVIEVDEAIKEEEEDEEEEGGGGGGRKSHKNLRSARVKRCPPSKKR
                     TQSIQGRSRSKRLSHDFVTPAMSRLEPSLVKPTPGMTPRFDSRVFKTPGLRTPAAKEQ
                     VYNISINGSPLADSKEISLSVPIGGGASLRLLASDLQRVDIAQLNPEALGNIKKLSSR
                     LAQICSSIRTGR"
     exon            223..351
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            352..392
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            393..465
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            466..578
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            579..643
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            644..736
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            737..863
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            864..950
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1513
                     /gene="Cdca8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcagagtt caggatacct agactccaac gactgaactt ccgctgctcc ccgaccactc
       61 acgccctctt tcccggtctc attcgctaac ccggcagctc ggcccctcgc tggacgcacc
      121 ctggtgtcat ggctcctaag aaacgcagca gccgcgggac caggaccaac acactgcgga
      181 gccggaagct cgcctccttc ctaaaggact tcgaccgcga ggtgcaagtt cgaaccaagc
      241 aaattgagtc cgacaggcag accctcctca aggaggtgga aaatctctac aacatcgagg
      301 tccttcggct ccccaaggcg ctgcaagtca tgaagtggct tgactacttt gccctaggag
      361 gaaacagaca ggccctggaa gaggcagcaa cagctgatcg agacatcaca gagataaaca
      421 atttaacagc tgaagctatt cagacacctt taaaatctgt taaaaagcga aaggtaatcg
      481 aggtggatga agccataaag gaagaggaag aagatgaaga agaagaagga ggaggaggag
      541 gaggaagaaa gagccataag aatcttcgat ctgcgagagt caaaagatgc cctccatcca
      601 agaagagaac ccagtctata caaggaagaa gcagaagcaa aaggttaagc catgactttg
      661 tgaccccagc tatgagcagg ctggagccat ctctggtgaa accaacccca ggcatgacac
      721 ctaggtttga ttccagggtc ttcaaaactc caggtctacg aaccccagcg gccaaggagc
      781 aggtttacaa catctctatc aacggcagcc ctctcgcaga cagcaaagag atctccctca
      841 gtgtgcccat aggtggcggt gcgagcttgc ggctattggc cagtgacttg cagagggtcg
      901 atattgctca gctgaatcca gaggccctgg gaaacattaa gaaactctcg agtcgccttg
      961 ctcagatctg cagcagcatc cggacaggcc gatgagagga cggcaaggca cacaggtggc
     1021 agcagggact gcagtggcag aacacacacc tgtgggtgcc tcacctgcca cacctgcagc
     1081 ggtgctttgc gtctctccaa cagctgtgat gtcgtgctgc acacttgtag ttagtgggaa
     1141 tttagatggg gaacacaggg ctagtggggg tctttgtgtg cttggtgtgg agtcactgag
     1201 aaccatccgt ggtttgagat cccaccgggg ctggacactg cttggagcac tgtggagggc
     1261 aagtgtaacc tttgccccgg gacccaggca ggctatgcag ccagcatagg gtgtgtggtc
     1321 cttgcaggtc taggcgcacg gctggctctc cctgttctgt tctgttgtta tttctgtcct
     1381 ctggacggga gtgcttcaga tgggttttct tttgctgagg gtcacacaca tcagtttctg
     1441 agcagttagc gtctcagccg actcgtccta tggaaagctt gctgttttca ataaatctta
     1501 gtttgctatc gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
