LOCUS       NM_001107063            2831 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus CDC42 effector protein 4 (Cdc42ep4), mRNA.
ACCESSION   NM_001107063 XM_001081647 XM_221077
VERSION     NM_001107063.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2831)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2831)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2831)
  AUTHORS   Trost,M., English,L., Lemieux,S., Courcelles,M., Desjardins,M. and
            Thibault,P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   4  (bases 1 to 2831)
  AUTHORS   Hirsch,D.S., Pirone,D.M. and Burbelo,P.D.
  TITLE     A new family of Cdc42 effector proteins, CEPs, function in
            fibroblast and epithelial cell shape changes
  JOURNAL   J Biol Chem 276 (2), 875-883 (2001)
   PUBMED   11035016
REFERENCE   5  (bases 1 to 2831)
  AUTHORS   Joberty,G., Perlungher,R.R. and Macara,I.G.
  TITLE     The Borgs, a new family of Cdc42 and TC10 GTPase-interacting
            proteins
  JOURNAL   Mol Cell Biol 19 (10), 6585-6597 (1999)
   PUBMED   10490598
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001107063.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161986.1, SRR26360194.2513886.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                JAXUCZ010000010.1  99296248-99296342   c
            96-2831             JAXUCZ010000010.1  99271750-99274485   c
FEATURES             Location/Qualifiers
     source          1..2831
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..2831
                     /gene="Cdc42ep4"
                     /note="CDC42 effector protein 4"
                     /db_xref="GeneID:303653"
                     /db_xref="RGD:1311567"
     exon            1..95
                     /gene="Cdc42ep4"
                     /inference="alignment:Splign:2.1.0"
     exon            96..2831
                     /gene="Cdc42ep4"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..1252
                     /gene="Cdc42ep4"
                     /note="CDC42 effector protein (Rho GTPase binding) 4"
                     /codon_start=1
                     /product="cdc42 effector protein 4"
                     /protein_id="NP_001100533.1"
                     /db_xref="GeneID:303653"
                     /db_xref="RGD:1311567"
                     /translation="MPILKQLVSGSVNSKRRSRADLTAEMISAPLGDFRHTMHVGRGG
                     DAFGDTSFLTSKTGEPDGESLDEQATSSKLSLLSRKFRGSKRSQSVTRGDREQRDMLG
                     SLRDSSLFVKNAMSLPQLNEKEATEKDSSKLPKSLSSSPVKKADTRDGSPKSPHRNGA
                     TGPHSPDPLLDEQAFGDLMDLPVMPKVSYGLKHAESILSFHIDLGPSMLGDVLSIMDK
                     DQWGSEEEGEEEGGIYRVKEGPGGIVQGPPMLEASPRGRQESKASWDHASMLPHHALE
                     DDGWAAVAPSPSSARSVGSHTTRDSSSLSSYTSGVLEERSPAFRGPDRVGAAPPRQPD
                     KEFSFMDEEEEDEIRV"
ORIGIN      
        1 cgctgccatg ggtcgccagc cttgccgagg cgccaagcac actgagggga gcacacagcc
       61 gcacctggtc cgtgctcggg gagctggggg ccgagccctc tgattgccct gtctaccctt
      121 tgcacttgct ggacttgaga tctgacccca cacctgcctg ttgccttggg agtgcccagc
      181 tccccccaca gccagcaaga tgcccattct caaacagctg gtgtccggct ctgtgaactc
      241 aaagcgacgc tcacgcgcgg acctcacagc ggagatgatc agtgccccac tgggtgactt
      301 ccgccacacc atgcatgtgg gccggggtgg ggatgccttt ggggacacct ccttcctcac
      361 tagcaagacg ggcgaacctg atggcgagtc cttggatgaa caggccacat cgtccaaact
      421 cagcctcctg tcccggaagt tccggggcag taaacgttca cagtctgtga ccagagggga
      481 ccgggagcag agagacatgc tgggctccct gcgggactca tcactgtttg tcaagaatgc
      541 catgtccctg cctcagctca atgagaagga agccactgag aaggactcca gcaagttacc
      601 caagagcttg tcatccagcc ctgtgaagaa ggcagatacg agagatggta gcccaaagag
      661 tccccatcgg aacggggcca cagggcccca ctcacctgac ccactccttg atgagcaggc
      721 ctttggggac ctgatggacc tacccgtcat gcccaaagtc agctacggcc tgaagcatgc
      781 tgagtcgatc ctgtccttcc acattgacct ggggccctcc atgctgggag atgtcctcag
      841 catcatggac aaggaccagt ggggctcgga ggaggaggga gaggaggaag gcggcattta
      901 ccgtgtcaaa gaaggccccg gtggcattgt ccaggggccc cctatgctgg aggcatctcc
      961 tcgagggagg caggaaagca aggccagctg ggaccatgcc tccatgctgc cccaccacgc
     1021 tctggaggat gacggttggg cagcggtcgc ccccagcccc agctcagcac gcagcgtggg
     1081 cagccatacc acacgggaca gcagttccct gtccagctac acctcaggcg tccttgagga
     1141 gcgcagccca gctttcagag gcccagacag ggtgggggct gctcccccaa ggcagccaga
     1201 caaggaattc tccttcatgg atgaggaaga ggaagacgag atccgagttt gaggctggac
     1261 agaaagttga aagtagcttc cacagctctg ggctgcatct tttccctgct gctgctgcct
     1321 tcactatgac ctttgacctt acttgtaggt gcagctaagc ctcatcggag tggaccctgg
     1381 acctcaggga ttgggatgcc cagggagtag catgagtact ggtgcctggc ggcctgactc
     1441 tgacctgtcc gtccttcccg caccagcttg ggacagagcc gagtctgcag gaatccattc
     1501 tcttccgggc cccttgcttc cagcctggcc tcagatggat gccagatgtt gtgagttcct
     1561 gctgcaatgg cagagcccca ggtgtggcct catggacact tggttccctt ttgttcacct
     1621 catgtctggt gcctaccagg gaggtaatgc agcaggaggc aggggtgccc acatattcgg
     1681 gctcctcctt cctccaccct tgcctcctta ctggaagcct ggtgctcttt gaggttcagc
     1741 tacagctggg ggacaacttc aactattaca ctaaatgcag cctttcccag gggccaggac
     1801 aggatggggc agagaaggaa cgccctgctc ccagcttttt gtggtctcaa gaaggacccc
     1861 ccacccccct cagcaacact agaaacagga aaggggccag cttggccggc ccgtgggtgt
     1921 gtttgttcct tgttgctatg tttaaacctg aatagagcac tgtcagaatc ccccaccaga
     1981 agagcgactg tcttggtggc agagtgactg ttatctgacc tgagttgggg tgtacaggcc
     2041 ctgcccagtg tttgtccctg aaccccccac ctccatagct gttaatggct gaatgaggaa
     2101 agttctggaa tatgatgctt aaataatgca ttatatccca gtgtgatgtg tgctttggct
     2161 cgttagtgtc ctctccttgg gttaagggcc aggcttagca aaaacacgaa acaaaacagg
     2221 accatatttg atttggattc cagggaaatg aacgtgggtt tttgtttgtt tggttttggc
     2281 tttttgaggt acagtctcac tctgtagccc aagccagcct caagctcctg caagcctccc
     2341 tttccctagg agctggggtt acaagtgtgc accacagttc ctggctcttt gtttttctga
     2401 aatctgtttt gctcggctcc tgtaactcta cccagaacaa gggtagaggc tgggacctga
     2461 gccctgggga ggtggtagct cattactttt ctgtgctggg agcaggctga cacactccct
     2521 ggtcaagcat agccagtggg aatctgggga gagagcaagc taaattacaa gcagagtctg
     2581 gccagatgat gaccagccat gggttgctct gcttccagag gcctccttct gatcctgaaa
     2641 tgctcactgg gctcctgact ggtgctccta cgcaggtagg cactgacaga actgcagagc
     2701 tgtgtctcta gccagcagca cacacacacc cctctcctaa atctacctgg ttggttctag
     2761 actctaaact ttgtattttt ttccatgaca ttgataaagc agtaagaaaa tattaaaatt
     2821 tcctcctagc a
//
